Previous Testing Proposals
Previous Testing Proposals
| Triethoxy(vinyl)silane | 201-081-7 | 78-08-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with trimethoxy(vinyl)silane (EC 220-449-8) Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with trimethoxy(vinyl)silane (EC 220-449-8) |
23/04/2018 23/04/2018 |
07/06/2018 07/06/2018 |
Details | |
| Amines, polyethylenepoly-, tetraethylenepentamine fraction | 292-587-7 | 90640-66-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with TETA (CAS 90640-67-8) and HEPA (68121-73-7) Reproductive toxicity (pre-natal developmental toxicity ) |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
| 3,6,9,12-tetraazatetradecamethylenediamine | 223-775-9 | 4067-16-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with structural analogues TETA (CAS 90640-67-8) and HEPA (CAS 68121-73-7). Reproductive toxicity (pre-natal developmental toxicity) |
22/11/2017 22/11/2017 |
08/01/2018 08/01/2018 |
Details | |
| sodium toluene-4-sulphonate | 211-522-5 | 657-84-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate (EC 215-090-9) | 16/12/2016 | 30/01/2017 | Details | |
| potassium 4-cumenesulfonate | 629-764-9 | 164524-02-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate (EC 215-090-9) | 16/12/2016 | 30/01/2017 | Details | |
| sodium p-cumenesulphonate | 239-854-6 | 15763-76-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium xylene sulphonate | 24/04/2015 | 12/06/2015 | Details | |
| Sodium toluene-4-sulphonate | 211-522-5 | 657-84-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with sodium (xylenes and 4-ethylbenzene) sulphonate Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate |
22/06/2017 22/06/2017 |
07/08/2017 07/08/2017 |
Details | |
| potassium 4-cumenesulfonate | 629-764-9 | 164524-02-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with sodium (xylenes and 4-ethylbenzene) sulphonate Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate |
22/06/2017 22/06/2017 |
07/08/2017 07/08/2017 |
Details | |
| Sodium p-cumenesulphonate | 239-854-6 | 15763-76-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Sodium (xylenes and 4-ethylbenzene) sulphonate Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with sodium cumene sulphonate |
22/06/2017 22/06/2017 |
07/08/2017 07/08/2017 |
Details | |
| Silver | 231-131-3 | 7440-22-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with silver(1+) acetate (CAS number 563-63-3) | 27/09/2017 | 13/11/2017 | Details | |
| zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) | 224-235-5 | 4259-15-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |
| Zinc bis[O-(6-methylheptyl)] bis[O-(sec-butyl)] bis(dithiophosphate) | 298-577-9 | 93819-94-4 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |
| Zinc O,O,O',O'-tetrakis(1,3-dimethylbutyl) bis(phosphorodithioate) | 218-679-9 | 2215-35-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Testing proposed according to a plan for the ZDDP category Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Testing proposed according to a plan for the ZDDP category. Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Testing proposed according to a plan for the ZDDP category.“ |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |
| Zinc bis(O,O-diisooctyl) bis(dithiophosphate) | 249-109-7 | 28629-66-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |
| Zinc bis[bis(tetrapropylenephenyl)] bis(hydrogen dithiophosphate) | 234-277-6 | 11059-65-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |
| Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) | 230-257-6 | 6990-43-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |
| Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Bu) esters, zinc salts | 270-478-5 | 68442-22-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category" Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |
| Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts | 283-392-8 | 84605-29-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing Proposed according to a plan for the ZDDP category" Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing Proposed according to a plan for the ZDDP category" |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |
| Phosphorodithioic acid, mixed O,O-bis(sec-Bu and 1,3-dimethylbutyl) esters, zinc salts | 272-238-5 | 68784-31-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing Proposed according to a plan for the ZDDP category" Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“ Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing Proposed according to a plan for the ZDDP category" |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |
| Propylidynetrimethanol, propoxylated | 500-041-9 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with analogue substance Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with analogue substance Sub-chronic toxicity (90-day): oral || Note: testing proposed with analogue substance |
05/07/2018 05/07/2018 05/07/2018 |
20/08/2018 20/08/2018 20/08/2018 |
Details | |
| C14-16 (even numbered) and C16 (branched) saturated and unsaturated aliphatic hydrocarbons | 700-762-0 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with an analogue substance. Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with an analogue substance. Sub-chronic toxicity (90-day): oral || Note: testing proposed with an analogue substance. |
01/10/2018 01/10/2018 01/10/2018 |
15/11/2018 15/11/2018 15/11/2018 |
Details | |
| 2,4,6,8,10-pentamethylcyclopentasiloxane | 228-204-7 | 6166-86-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (EC 219-137-4) | 25/05/2020 | 09/07/2020 | Details | |
| 2,4,6,8,10-pentamethylcyclopentasiloxane | 228-204-7 | 6166-86-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (CAS 2370-88-9; EC 219-137-4; HD4) Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (CAS 2370-88-9; EC 219-137-4; HD4) |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
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Details |
| (6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | 261-491-7 | 58909-56-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
10/08/2018 10/08/2018 10/08/2018 |
24/09/2018 24/09/2018 24/09/2018 |
Details | |
| 3-acetoxymethylen-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | 213-485-0 | 957-68-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
10/08/2018 10/08/2018 10/08/2018 |
24/09/2018 24/09/2018 24/09/2018 |
Details | |
| Reaction products of pentaerythritol, propoxylated and 1-chloro-2,3-epoxypropane with hydrogen sulfide | 701-196-7 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
| Amines, tallow alkyl, dodecylbenzenesulfonates | 268-766-0 | 68139-94-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/11/2015 30/11/2015 30/11/2015 |
14/01/2016 14/01/2016 14/01/2016 |
Details | |
| Reaction products of a polyol of pentaerythritol and propylene oxide, epichlorohydrin and hydrogen sulfide | 615-735-8 | 72244-98-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant Reproductive toxicity (pre-natal developmental toxicity) |
11/11/2016 11/11/2016 |
03/01/2017 03/01/2017 |
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Details |
| 1,1,3,3-tetramethylbutyl peroxyneodecanoate | 257-077-0 | 51240-95-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant | 01/09/2017 | 16/10/2017 | Details | |
| Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts | 272-723-1 | 68909-93-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: substance to be tested is Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0; CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Reproductive toxicity (pre-natal developmental toxicity) || Note: substance to be tested is Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0; CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Sub-chronic toxicity (90-day): oral || Note: substance to be tested is Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0; CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |
| Tetrahydrothiophene 1,1-dioxide | 204-783-1 | 126-33-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) / Testing proposal is based on concern identified by the registrant. | 23/04/2018 | 07/06/2018 | Details | |
| Alkenes, C13-14, hydroformylation products, distn. residues | 292-429-7 | 90622-29-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with Alkenes, C11-12, hydroformylation products, distn. residues (EC 292-427-6) | 02/11/2018 | 17/12/2018 | Details | |
| Sulphamidic acid | 226-218-8 | 5329-14-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with ammonium sulphamate (pH consideration) | 23/04/2018 | 07/06/2018 | Details | |
| trisodium 2-(2-sulfoethoxy)ethane-1-sulfonate ethenesulfonate | 700-978-5 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) Note: testing proposed with Sodium ethylenesulphonate (EC No. 221-242-5) | 03/05/2023 | 19/06/2023 | Details | |
| Shale oils | 269-646-0 | 68308-34-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with Shale oils, heavy fractions (Registration No 01-2119756217-35-0000)” Sub-chronic toxicity (90-day): oral “|| Note: testing proposed with Shale oils, heavy fractions (Registration No 01-2119756217-35-0000)” | 14/03/2016 | 28/04/2016 | Details | |
| Shale oils, light | 923-592-0 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with Shale oils, heavy fraction (Registration No 01-2119756217-35-0000)||” Sub-chronic toxicity (90-day): oral “|| Note: testing proposed with Shale oils, heavy fraction (Registration No 01-2119756217-35-0000)||” | 14/03/2016 | 28/04/2016 | Details | |
| [1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide | 218-664-7 | 2212-81-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with [1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide CAS: 25155-25-3)” | 25/05/2020 | 09/07/2020 | Details | |
| O,O,O-triphenyl phosphorothioate | 209-909-9 | 597-82-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: Testing proposal is based on concern identified by the registrant.” | 03/02/2016 | 21/03/2016 |
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Details |
| Alkanes, C12-14-iso- | 271-369-5 | 68551-19-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Hydrocarbons, C7-C9, isoalkanes (EC 921-728-3)
|| Note: testing proposed with Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane (EC 224-506-8) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Hydrocarbons, C7-C9, isoalkanes (EC 921-728-3)
|| Note: testing proposed with Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane (EC 224-506-8) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Hydrocarbons, C7-C9, isoalkanes (EC 921-728-3)
|| Note: testing proposed with Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane (EC 224-506-8) |
23/11/2020 23/11/2020 23/11/2020 |
07/01/2021 07/01/2021 07/01/2021 |
Details | |
| Hexene | 246-768-2 | 25264-93-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Hex-1-ene (EC 209-753-1)
|| Note: testing proposed with Octadec-1-ene (EC 112-88-9)
|| Note: testing proposed with Hexadecene (EC 248-131-4)
|| Note: testing proposed with Alkenes, C8-10, C9-rich (EC 271-212-0)
|| Note: testing proposed with Nonene, branched (EC 306-492-6) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Hex-1-ene (EC 209-753-1)
|| Note: testing proposed with Octadec-1-ene (EC 112-88-9)
|| Note: testing proposed with Octadecene (EC 248-205-6)
|| Note: testing proposed with Alkenes, C8-10, C9-rich (EC 271-212-0)
|| Note: testing proposed with Nonene, branched (EC 306-492-6) |
23/11/2020 23/11/2020 |
07/01/2021 07/01/2021 |
Details | |
| Fuels, diesel, co-processed with hydrocarbons derived from thermally cracked waste plastics | 951-495-3 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with - Gas oils (petroleum), light vacuum (EC 265-059-9) - Fuel oil, no. 4 (EC 270-673-5) - Distillates (petroleum), light hydrocracked (EC 265-078-2) - Fuels, diesel (EC 269-822-7) |
24/08/2020 24/08/2020 |
08/10/2020 08/10/2020 |
Details | |
| Dimethyl(propyl)amine | 213-139-9 | 926-63-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Ethyldimethylamine (EC 209-940-8) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Ethyldimethylamine (EC 209-940-8) |
18/02/2021 18/02/2021 |
05/04/2021 05/04/2021 |
Details | |
| Reaction mass of Ethanaminium, 2-hydroxy-N,N-dimethyl-N-[2-[(1-oxooctadecyl)oxy]ethyl]-, chloride and Ethanaminium, N,N-dimethyl-2-[(1-oxohexadecyl)oxy]-N-[2-[(1-oxooctadecyl)oxy]ethyl]-, chloride | 951-974-7 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Ethanaminium, 2-hydroxy-N-(2-hydroxyethyl)-N,N-dimethyl-, esters with C16-18 and C18-unsatd. fatty acids, chlorides (EC 620-174-7) | 23/11/2020 | 07/01/2021 | Details | |
| Distillates (petroleum), straight-run middle | 265-044-7 | 64741-44-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Distillates (petroleum), heavy straight-run (EC 272-817-2) | 23/11/2020 | 07/01/2021 | Details | |
| Distillates (petroleum), full-range straight-run middle | 272-341-5 | 68814-87-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Distillates (petroleum), heavy straight-run (EC 272-817-2) (CAS 68915-96-8) | 21/01/2021 | 08/03/2021 | Details | |
| Diethylamine | 203-716-3 | 109-89-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Dimethylamine (CAS 124-40-3) | 21/09/2020 | 05/11/2020 | Details | |
| Choline hydroxide | 204-625-1 | 123-41-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Choline chloride (EC 200-655-4) | 25/05/2020 | 09/07/2020 | Details | |
| Barium sulfate | 231-784-4 | 7727-43-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Barium chloride (EC 233-788-1) | 17/06/2020 | 03/08/2020 | Details | |
| Residues (petroleum), thermal cracked vacuum | 295-518-9 | 062-05-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Asphalt (CAS 8052-42-4) | 25/06/2019 | 09/08/2019 | Details | |
| 2,2'-(C16-18 (evennumbered, C18 unsaturated) alkyl imino) diethanol | 620-540-6 | 1218787-32-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,2'-(Octadec-9-enylimino) bisethanol, CAS No 25307-17-9 | 14/03/2016 | 28/04/2016 |
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Details |
| 1-ethoxy-2-(2-methoxyethoxy)ethane | 213-690-5 | 1002-67-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
25/05/2020 25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 09/07/2020 |
Details | |
| Dipotassium bis[μ-[tartrato(4-)-O1,O2:O3,O4]]diantimonate(2-) , stereoisomer | 234-293-3 | 11071-15-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) |
25/05/2020 25/05/2020 |
09/07/2020 09/07/2020 |
Details | |
| p-tert-butylstyrene | 217-126-9 | 1746-23-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. | 25/05/2020 | 09/07/2020 | Details | |
| Platinum, 1,3-diethenyl-1,1,3,3-tetramethyldisiloxane complexes | 701-315-2 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. | 25/05/2020 | 09/07/2020 | Details | |
| 2-methylpropene | 204-066-3 | 115-11-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: substance belongs to a category and testing is proposed with the Substance (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: substance belongs to a category and testing is proposed with the Substance (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) Sub-chronic toxicity (90 day): inhalation
|| Note: substance belongs to a category and testing is proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) |
16/12/2020 16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 01/02/2021 |
Details | |
| 2-butene | 203-452-9 | 107-01-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: substance belongs to a category and testing is proposed with 2-methylpropene (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: substance belongs to a category and testing is proposed with 2-methylpropene (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) Sub-chronic toxicity (90 day): inhalation
|| Note: substance belongs to a category and testing is proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) |
16/12/2020 16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 01/02/2021 |
Details | |
| But-1-ene | 203-449-2 | 106-98-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: substance belongs to a category and testing is proposed with 2-methylpropene (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: substance belongs to a category and testing is proposed with 2-methylpropene (EC 204-066-3) and Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) Sub-chronic toxicity (90 day): inhalation
|| Note: substance belongs to a category and testing is proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC 306-004-1) |
16/12/2020 16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 01/02/2021 |
Details | |
| Heptanal | 203-898-4 | 111-71-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Heptanoic acid (CAS No. 111-14-8) |
25/11/2019 | 09/01/2020 | Details | |
| Asphalt | 232-490-9 | 8052-42-4 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
[note whilst the registrant has selected the drop down of a RaX TPE – it is not a RaX TPE – registered substance is being tested]” |
25/06/2019 | 09/08/2019 | Details | |
| Naphtha (petroleum), steam-cracked middle arom. | 271-138-9 | 68516-20-1 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: This substance belongs to a category. Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: This substance belongs to a category. Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Sub-chronic toxicity (90-day): oral
|| Note: This substance belongs to a category. Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) |
22/04/2021 22/04/2021 22/04/2021 |
07/06/2021 07/06/2021 07/06/2021 |
Details | |
| Extracts (petroleum), heavy naphtha solvent | 265-099-7 | 64741-98-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with this substance and with Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with this substance and with Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Sub-chronic toxicity (90-day): oral
|| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with this substance and with Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) |
22/04/2021 22/04/2021 22/04/2021 |
07/06/2021 07/06/2021 07/06/2021 |
Details | |
| Solvent naphtha (petroleum), heavy arom. | 265-198-5 | 64742-94-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) Sub-chronic toxicity (90-day): oral
|| Note: This substance belongs to a category (“Low Benzene Naphthas”). Testing proposed with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) and Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction (EC 270-728-3) |
22/04/2021 22/04/2021 22/04/2021 |
07/06/2021 07/06/2021 07/06/2021 |
Details | |
| Distillates (petroleum), cracked stripped steam-cracked petroleum distillates, C8-10 fraction | 270-728-3 | 68477-39-4 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: The substance belongs to a category (“Low Benzene Naphthas”). Testing is proposed with this substance and with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: The substance belongs to a category (“Low Benzene Naphthas”). Testing is proposed with this substance and with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) Sub-chronic toxicity (90-day): oral
|| Note: The substance belongs to a category (“Low Benzene Naphthas”). Testing is proposed with this substance and with Extracts (petroleum), heavy naphtha solvent (EC 265-099-7) |
22/04/2021 22/04/2021 22/04/2021 |
07/06/2021 07/06/2021 07/06/2021 |
Details | |
| Vanadium oxide sulphate | 248-652-7 | 27774-13-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with sodium metavanadate (EC 237-272-7) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with sodium metavanadate (EC 237-272-7) |
01/04/2022 01/04/2022 |
16/05/2022 16/05/2022 |
Details | |
| Reaction mass of dibutyl adipate and dibutyl glutarate | 936-196-8 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Reaction mass of dimethyl adipate, dimethyl glutarate and dimethyl succinate (EC 906-170-0) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Reaction mass of dimethyl adipate, dimethyl glutarate and dimethyl succinate (EC 906-170-0) |
16/12/2020 16/12/2020 |
01/02/2021 01/02/2021 |
Details | |
| Phthalic acid | 201-873-2 | 88-99-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with phthalic anhydride (EC no. 201-607-5) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with phthalic anhydride (EC no. 201-607-5) |
21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 |
Details | |
| Zinc O,O,O',O'-tetrakis(1,3-dimethylbutyl) bis(phosphorodithioate) | 218-679-9 | 2215-35-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with, zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5) |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
| Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts | 272-723-1 | 68909-93-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with the substance, with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with the substance, with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5) |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
| zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) | 224-235-5 | 4259-15-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with the substance and with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with the substance and with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8) |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
| Zinc bis(O,O-diisooctyl) bis(dithiophosphate) | 249-109-7 | 28629-66-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), and Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5) |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
| Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Bu) esters, zinc salts | 270-478-5 | 68442-22-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) and another relevant read-across member of the ZDDP category Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), and Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5) |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
| Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts | 283-392-8 | 84605-29-8 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) and another read-across member from ZDDP category Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with the substance, with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5) and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed the substance, with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6) and Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5) |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
| m-xylene | 203-576-3 | 108-38-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with p-xylene (EC 203-396-5) | 18/02/2021 | 05/04/2021 | Details | |
| o-xylene | 202-422-2 | 95-47-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with p-xylene (EC 203-396-5) | 22/04/2021 | 07/06/2021 | Details | |
| 1-Dodecene, dimer with 1-decene, hydrogenated | 604-766-2 | 151006-58-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-decene, dimer (EC 917-709-4) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-Dodecene, Dimer (EC 814-509-8) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-Dodecene, dimer, hydrogenated (EC 604-768-3) |
01/07/2021 01/07/2021 01/07/2021 |
16/08/2021 16/08/2021 16/08/2021 |
Details | |
| Branched hexatriacontane | 417-070-7 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-decene, dimer (EC 917-709-4), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9), 1-Dodecene, Dimer (EC 814-509-8 ), Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Dodecene, dimer, hydrogenated (EC 604-768-3) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) |
26/08/2021 26/08/2021 26/08/2021 |
11/10/2021 11/10/2021 11/10/2021 |
Details | |
| Barium hydroxide | 241-234-5 | 17194-00-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Barium chloride dihydrate (EC 600-412-6) | 16/12/2020 | 01/02/2021 | Details | |
| Phosphorodithioic acid, mixed O,O-bis(sec-Bu and 1,3-dimethylbutyl) esters, zinc salts | 272-238-5 | 68784-31-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with another ZDDP read-across category member depending on the outcome of the other testing proposals Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
| Zinc bis[O-(2-ethylhexyl)] bis[O-(isobutyl)] bis(dithiophosphate) | 247-810-2 | 26566-95-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with another ZDDP category member to be determined based on outcome of other testing proposals Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6) |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
| Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide | 271-794-6 | 68608-66-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Alkylamidoamine glycinate majority C12, 14 (amphoacetate) EC 931-291-0
|| Note: Testing proposal is based on concern identified by the registrant Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Alkylamidoamine glycinate majority C12, 14 (amphoacetate) EC 931-291-0.
|| Note: Testing proposal is based on concern identified by the registrant |
19/10/2020 19/10/2020 |
03/12/2020 03/12/2020 |
Details | |
| Carboxylic acids, di-, C4-6 | 271-678-5 | 68603-87-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with adipic acid (EC 204-673-3) | 21/10/2021 | 07/12/2021 | Details | |
| Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Bu and pentyl) esters, zinc salts | 273-527-9 | 68988-45-4 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with a read-across member of the ZDDP category(identity of test material not yet decided) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), and Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6) |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
| Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Bu and iso-Pr) esters, zinc salts | 288-917-4 | 85940-28-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with a read-across member of the ZDDP category Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), Zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1) |
21/12/2021 21/12/2021 21/12/2021 |
04/02/2022 04/02/2022 04/02/2022 |
Details | |
| Propanol, oxybis-, polymer with 1,1'-methylenebis[4-isocyanatobenzene] | 701-040-8 | 59952-43-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |
| 1,3-Butanediol, reaction products with 1,1'-methylenebis[4-isocyanatobenzene], propylene glycol and tripropylene glycol | 941-496-7 | 1689576-89-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |
| 1-isocyanato-2(or 4)-(4-isocyanatobenzyl)benzene and their reaction products with [(methylethylene)bis(oxy)]dipropanol and butane-1,3-diol and propylene glycol | 701-029-8 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |
| 2,2'-methylenediphenyl diisocyanate | 219-799-4 | 2536-05-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |
| o-(p-isocyanatobenzyl)phenyl isocyanate | 227-534-9 | 5873-54-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |
| 1,1'-methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with butane-1,3-diol, 2,2'-oxydiethanol and propane-1,2-diol | 701-173-1 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |
| Reaction mass of 2,5,8,11-tetraoxatridecan-13-ol and 2,5,8,11,14-pentaoxahexadecan-16-ol | 915-389-0 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC no. 203-962-1) | 01/04/2022 | 16/05/2022 | Details | |
| 2-(2-(2-ethoxyethoxy)ethoxy)ethanol | 203-978-9 | 112-50-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1) | 21/10/2021 | 07/12/2021 | Details | |
| 3,6,9,12-tetraoxotridecanol | 245-883-5 | 23783-42-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1) | 21/10/2021 | 07/12/2021 | Details | |
| 1-Dodecene, dimers | 814-509-8 | 62132-67-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with 1-decene, homopolymer, hydrogenated (EC 500-183-1), 1-Decene trimer, hydrogenated and tetramers (EC 614-695-9) and 1-decene, dimer, unhydrogenated (EC 917-709-4) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with the Substance, 1-decene, homopolymer, hydrogenated (EC 500-183-1), and 1-Decene trimer, hydrogenated and tetramers (EC 614-695-9) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with 1-Decene trimer, hydrogenated and tetramers (EC 614-695-9) and 1-Dodecene, dimer, hydrogenated (EC 604-768-3) |
18/03/2021 18/03/2021 18/03/2021 |
03/05/2021 03/05/2021 03/05/2021 |
Details | |
| A mixture of isomers of branched tetracosane | 417-060-2 | 151006-61-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with 1-decene, dimer (EC 917-709-4), Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9), 1-Dodecene, Dimer (EC 814-509-8 ) and Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-Dodecene, dimer, hydrogenated (EC 604-768-3) |
01/07/2021 01/07/2021 01/07/2021 |
16/08/2021 16/08/2021 16/08/2021 |
Details | |
| 1,1'-Methylenebis(4-isocyanatobenzene) and its oligomeric reaction products with [(methylethylene)bis(oxy)]dipropanol | 701-124-4 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |
| 2,2'-(octadecylimino)bisethanol | 233-520-3 | 10213-78-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,2'-(octadec-9-enylimino)bisethanol EC 246-807-3 | 16/12/2020 | 01/02/2021 | Details | |
| Formaldehyde, oligomeric reaction products with aniline and phosgene | 500-079-6 | 32055-14-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC 202-966-0) | 01/04/2022 | 16/05/2022 | Details | |
| Alcohols, C13-15-branched and linear | 287-625-4 | 85566-16-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Isotridecan-1-ol (EC 248-469-2) | 16/12/2020 | 01/02/2021 | Details | |
| Octasodium 2,2'-[1,4-phenylenebis[imino(6-chloro-1,3,5-triazine-4,2-diyl)imino(1-hydroxy-3,6-disulphonatonaphthalene-2,8-diyl)azo]]bisnaphthalene-1,5-disulphonate | 275-108-6 | 71002-20-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant | 16/12/2020 | 01/02/2021 | Details | |
| (R)-p-mentha-1,8-diene | 227-813-5 | 5989-27-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/05/2020 | 09/07/2020 | Details | |
| 1,1'-(ethane-1,2-diyl)bis[pentabromobenzene] | 284-366-9 | 84852-53-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 24/02/2020 | 09/04/2020 | Details | |
| 1,1'-isopropylidenebis(p-phenyleneoxy)dipropan-2-ol | 204-137-9 | 116-37-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/03/2018 | 11/05/2018 | Details | |
| 1,2,3,4-tetrahydronaphthalene | 204-340-2 | 119-64-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/03/2018 | 11/05/2018 | Details | |
| 1-butylpyrrolidin-2-one | 222-437-8 | 3470-98-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/01/2022 | 11/03/2022 | Details | |
| 1-Hexanol, 2-ethyl-, manuf. of, by-products from, distn. residues | 271-832-1 | 68609-68-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/03/2018 | 11/05/2018 | Details | |
| 2,2'-(octadec-9-enylimino)bisethanol | 246-807-3 | 25307-17-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 01/09/2017 | 16/10/2017 |
|
Details |
| 2,2'-[hexane-1,6-diylbis(oxymethylene)]dioxirane | 618-939-5 | 933999-84-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/10/2017 | 11/12/2017 |
|
Details |
| 2,2'-[oxybis(methylene)]bis[2-ethylpropane-1,3-diol] | 245-509-0 | 23235-61-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/03/2018 | 11/05/2018 | Details | |
| 2,2,2',2'-Tetrakis(hydroxymethyl)-3,3'-oxydipropan-1-ol | 204-794-1 | 126-58-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 01/04/2022 | 16/05/2022 | Details | |
| 2,2-bis[[(1-oxopentyl)oxy]methyl]propane-1,3-diyl divalerate | 239-937-7 | 15834-04-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 21/10/2019 | 05/12/2019 | Details | |
| 2,3-epoxypropyl neodecanoate | 247-979-2 | 26761-45-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |
| 2,4,4-trimethylpentene | 246-690-9 | 25167-70-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 15/07/2022 | 29/08/2022 | Details | |
| 2,4,6,8-tetramethylcyclotetrasiloxane | 219-137-4 | 2370-88-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/05/2020 | 09/07/2020 | Details | |
| 2,5-Furandione, dihydro-, mono-C15-20-alkenyl derivs. | 272-221-2 | 68784-12-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |
| 2,6-dimethyloct-7-en-2-ol | 242-362-4 | 18479-58-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 01/09/2017 | 16/10/2017 |
|
Details |
| 2-(2-(2-methoxyethoxy)ethoxy)ethanol | 203-962-1 | 112-35-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 21/10/2019 | 05/12/2019 | Details | |
| 2-Butyne-1,4-diol, polymer with 2-(chloromethyl)oxirane, brominated, dehydrochlorinated, methoxylateddehydrochlorinated, methoxylated | 614-503-3 | 68441-62-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
| 2-chloropropane | 200-858-8 | 75-29-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/03/2018 | 11/05/2018 | Details | |
| 2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate | 239-701-3 | 15625-89-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/10/2022 | 12/12/2022 | Details | |
| 2-piperazin-1-ylethylamine | 205-411-0 | 140-31-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 01/09/2017 | 16/10/2017 |
|
Details |
| 3-((C12-18)-acylamino)-N-(2-((2-hydroxyethyl)amino)-2-oxoethyl)-N,N-dimethyl-1-propanaminium chloride | 427-370-1 | 164288-56-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 03/04/2023 | 22/05/2023 | Details | |
| 3-methoxy-3-methylbutan-1-ol | 260-252-4 | 56539-66-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 30/09/2021 | 15/11/2021 | Details | |
| 3-methyldecane; benzene; cyclooctane; nonane | 941-364-9 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 05/07/2018 | 20/08/2018 |
|
Details |
| 4,4'-methylenedi-2,6-xylenol | 226-378-9 | 5384-21-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 03/04/2023 | 22/05/2023 | Details | |
| 4,4'-methylenediphenyl diisocyanate | 202-966-0 | 101-68-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/11/2021 | 10/01/2022 | Details | |
| 6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol | 204-327-1 | 119-47-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |
| [1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide | 246-678-3 | 25155-25-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 27/05/2019 | 11/07/2019 | Details | |
| A mixture of: cis-tetrahydro-2-isobutyl-4-methylpyran-4-ol; trans-tetrahydro-2-isobutyl-4-methylpyran-4-ol | 405-040-6 | 63500-71-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/06/2015 | 10/08/2015 | Details | |
| Adipic acid | 204-673-3 | 124-04-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 18/02/2021 | 05/04/2021 | Details | |
| Alcohols, C12-14, ethoxylated | 500-213-3 | 68439-50-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/10/2022 | 12/12/2022 | Details | |
| Alcohols, C18-22, distn. residues | 641-136-6 | 1160164-88-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |
| Alkenes, C11-12, hydroformylation products, distn. Residues | 292-427-6 | 90622-27-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
| Alkenes, C6-11 (branched), hydroformylation products, distn. residues, heavy cracked fraction | 701-314-7 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 31/01/2023 | 17/03/2023 | Details | |
| Alkenes, C7-9, hydroformylation products, distn. residues, heavy cracked fraction | 308-482-7 | 98072-31-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 02/11/2018 | 17/12/2018 | Details | |
| Amines, polyethylenepoly- | 268-626-9 | 68131-73-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 01/09/2017 | 16/10/2017 | Details | |
| Amines, polyethylenepoly- | 268-626-9 | 68131-73-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 22/11/2017 | 08/01/2018 | Details | |
| Amines, polyethylenepoly-, tetraethylenepentamine fraction | 292-587-7 | 90640-66-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 01/11/2015 | 16/12/2015 | Details | |
| Asphalt, oxidized | 265-196-4 | 64742-93-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/06/2019 | 09/08/2019 | Details | |
| Barium chloride | 233-788-1 | 10361-37-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/03/2018 | 11/05/2018 | Details | |
| Benzenamine, N-phenyl-, reaction products with 2,4,4-trimethylpentene | 270-128-1 | 68411-46-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/10/2017 | 11/12/2017 |
|
Details |
| Benzoic acid, 2-hydroxy-, mono-C14-18-alkyl derivs., calcium salts (2:1) | 931-276-9 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |
| Bis(2-(2-butoxyethoxy)ethoxy)methane | 205-598-9 | 143-29-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/03/2018 | 11/05/2018 | Details | |
| Bis(4-chlorophenyl) sulphone | 201-247-9 | 80-07-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
| bis(α,α-dimethylbenzyl) peroxide | 201-279-3 | 80-43-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 10/05/2022 | 27/06/2022 | Details | |
| bis(α,α-dimethylbenzyl) peroxide | 201-279-3 | 80-43-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 16/12/2020 | 01/02/2021 | Details | |
| Butane-1,4-diol | 203-786-5 | 110-63-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 22/04/2021 | 07/06/2021 | Details | |
| C,C'-azodi(formamide) | 204-650-8 | 123-77-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/11/2021 | 10/01/2022 | Details | |
| Calcium cyanamide | 205-861-8 | 156-62-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
| Citral | 226-394-6 | 5392-40-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
| Decahydronaphthalene | 202-046-9 | 91-17-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |
| Dichloromethylbenzene | 249-854-8 | 29797-40-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 22/06/2017 | 07/08/2017 |
|
Details |
| Diethyl ether | 200-467-2 | 60-29-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 02/11/2018 | 17/12/2018 | Details | |
| Dimethoxymethane | 203-714-2 | 109-87-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/03/2018 | 11/05/2018 | Details | |
| Dimethyl sulfoxide | 200-664-3 | 67-68-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 31/01/2023 | 17/03/2023 | Details | |
| Dimethylamine | 204-697-4 | 124-40-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
| Dioctadecyl 3,3'-thiodipropionate | 211-750-5 | 693-36-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 03/04/2023 | 22/05/2023 | Details | |
| Ethanol, 2,2'-iminobis-, N-C12-18-alkyl derivs. | 276-014-8 | 71786-60-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/06/2019 | 09/08/2019 |
|
Details |
| Ethylenediamine, salt with phosphoric acid | 238-914-9 | 14852-17-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 27/01/2020 | 12/03/2020 | Details | |
| Extracts (petroleum), residual oil solvent | 265-110-5 | 64742-10-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 06/06/2023 | 21/07/2023 | Details | |
| Fatty acids, C14-C18 and C18 unsaturated, amides with 2,2’-iminodiethanol | 948-052-1 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 21/01/2021 | 08/03/2021 | Details | |
| Geraniol | 203-377-1 | 106-24-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/10/2017 | 11/12/2017 |
|
Details |
| Heptanoic acid | 203-838-7 | 111-14-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 24/07/2019 | 09/09/2019 | Details | |
| hexadecyltrimethoxysilane | 240-464-3 | 16415-12-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/05/2020 | 09/07/2020 | Details | |
| Hexahydro-4-methylphthalic anhydride | 243-072-0 | 19438-60-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
| Hydrocarbons, C14-C16, n-alkanes, <2% aromatics | 921-535-4 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 02/11/2018 | 17/12/2018 | Details | |
| Hydrocarbons, C16-C18, isoalkanes,<2% aromatics | 948-766-3 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2019 | 15/04/2019 | Details | |
| Hydroxycyclohexyl phenyl ketone | 213-426-9 | 947-19-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 17/09/2019 | 01/11/2019 | Details | |
| inorganic phosphorus salt | 428-310-5 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/03/2018 | 11/05/2018 | Details | |
| Isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol | 246-771-9 | 25265-77-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 22/09/2022 | 07/11/2022 | Details | |
| Isononanoic acid, C16-18 (even numbered)-alkyl esters | 601-141-6 | 111937-03-2 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 18/06/2018 | 02/08/2018 | Details | |
| Isotridecan-1-ol | 248-469-2 | 27458-92-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 16/12/2020 | 01/02/2021 | Details | |
| Linalyl acetate | 204-116-4 | 115-95-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 17/06/2020 | 03/08/2020 | Details | |
| Magnesium, bis(2-hydroxybenzoato-O1,O2)-, ar,ar'-di-C14-18alkyl derivs | 931-371-5 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |
| Melamine | 203-615-4 | 108-78-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 17/05/2016 | 01/07/2016 |
|
Details |
| Menthol | 201-939-0 | 89-78-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 01/09/2017 | 16/10/2017 | Details | |
| Methyl 4-[[(2,5-dichlorophenyl)amino]carbonyl]-2-[[2-hydroxy-3-[[(2-methoxyphenyl)amino]carbonyl]-1-naphthyl]azo]benzoate – bulk and nano forms | 263-272-1 | 61847-48-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 03/10/2023 | 17/11/2023 | Details | |
| n-methyl-n-[c18-(unsaturated)alkanoyl]glycine | 701-177-3 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 21/10/2021 | 07/12/2021 | Details | |
| N-vinylformamide | 236-102-9 | 13162-05-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 01/11/2015 | 16/12/2015 | Details | |
| Nickel | 231-111-4 | 7440-02-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2019 | 15/04/2019 | Details | |
| Octene, hydroformylation products, high-boiling | 271-237-7 | 68526-89-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |
| p-xylene | 203-396-5 | 106-42-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 18/02/2021 | 05/04/2021 | Details | |
| Phenol, 2-methoxy-, reaction products with 2,2-dimethyl-3-methylenebicyclo[2.2.1]heptane, hydrogenated | 275-062-7 | 70955-71-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/08/2021 | 11/10/2021 | Details | |
| Phenol, isopropylated, phosphate (3:1) | 273-066-3 | 68937-41-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/03/2018 | 11/05/2018 | Details | |
| Polysulfides, di-tert-dodecyl | 270-335-7 | 68425-15-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 18/03/2021 | 03/05/2021 | Details | |
| potassium 4-isopropylbenzenesulphonate | 629-764-9 | 164524-02-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/06/2015 | 10/08/2015 | Details | |
| Potassium cyanate | 209-676-3 | 590-28-3 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |
| Propanamide, 2-hydroxy-N,N-dimethyl- | 609-066-0 | 35123-06-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 18/03/2021 | 03/05/2021 | Details | |
| Propanamide, 2-hydroxy-N,N-dimethyl- | 609-066-0 | 35123-06-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 21/10/2021 | 07/12/2021 | Details | |
| Propylidynetrimethyl trimethacrylate | 221-950-4 | 3290-92-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/04/2019 | 10/06/2019 | Details | |
| Reaction mass of 1-methyl-4-(1-methylethylidene)cyclohexyl acetate and p-menth-1-en-8-yl acetate | 904-693-9 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 04/09/2023 | 19/10/2023 | Details | |
| Reaction mass of 2,2'-{methylenebis[(2,6-dimethyl-4,1-phenylene)oxymethylene]}dioxirane and 1,3-bis{4-[3,5-dimethyl-4-(oxiran-2-ylmethoxy)benzyl]-2,6-dimethylphenoxy}propan-2-ol and 3,3'-{methylenebis[(2,6-dimethyl-4,1-phenylene)oxy]}bis(1-{4-[3,5-dimethyl-4-(oxiran-2-ylmethoxy)benzyl]-2,6-dimethylphenoxy}propan-2-ol) | 941-357-0 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 21/10/2019 | 05/12/2019 | Details | |
| Reaction mass of 4-tert-butylphenyl diphenyl phosphate and bis(4-tert-butylphenyl) phenyl phosphate and triphenyl phosphate | 700-990-0 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 22/09/2022 | 07/11/2022 | Details | |
| Reaction Mass of Benzyl (1R,1S) 2,2,4-trimethyl-1-[(2-methylpropanoyl)oxy]pentan-3-yl benzene-1,2-dicarboxylate and Benzyl (3R,3S) 2,2,4-trimethyl-3-[(2-methylpropanoyl)oxy]pentyl benzene-1,2-dicarboxylate | 701-008-3 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 27/05/2019 | 11/07/2019 | Details | |
| Reaction mass of propylidynetrimethanol and 2-ethylpropane-1,3-diol and 5-ethyl-1,3-dioxane-5-methanol | 904-153-2 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 18/02/2021 | 05/04/2021 | Details | |
| Reaction products of di-, tri- and tetra-propoxylated propane-1,2-diol with ammonia | 618-561-0 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 28/02/2018 | 16/04/2018 | Details | |
| Reaction products of diphenylamine with nonene, branched | 701-385-4 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 01/04/2022 | 16/05/2022 | Details | |
| Residues (petroleum), vacuum | 265-057-8 | 64741-56-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/06/2019 | 09/08/2019 | Details | |
| sodium cumenesulphonate | 239-854-6 | 15763-76-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 16/12/2016 | 30/01/2017 | Details | |
| Sodium dihydrogenorthophosphate | 231-449-2 | 7558-80-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 01/09/2016 | 17/10/2016 |
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Details |
| sodium toluene-4-sulphonate | 211-522-5 | 657-84-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 30/09/2015 | 16/11/2015 | Details | |