Previous Testing Proposals
Previous Testing Proposals
Previous Testing Proposals
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
Further instructions
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
There are currently no ongoing consultations.
| 2,2,6,6-tetramethyl-4-oxopiperidinooxy | 220-778-7 | 2896-70-0 | Sub-chronic toxicity (90-day): oral | 03/04/2023 | 22/05/2023 | Details | |
| 3-((C12-18)-acylamino)-N-(2-((2-hydroxyethyl)amino)-2-oxoethyl)-N,N-dimethyl-1-propanaminium chloride | 427-370-1 | 164288-56-6 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 03/04/2023 | 22/05/2023 | Details | |
| 4,4'-methylenedi-2,6-xylenol | 226-378-9 | 5384-21-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 03/04/2023 | 22/05/2023 | Details | |
| Dioctadecyl 3,3'-thiodipropionate | 211-750-5 | 693-36-7 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 03/04/2023 | 22/05/2023 | Details | |
| Dodecyl methacrylate | 205-570-6 | 142-90-5 | Sub-chronic toxicity (90-day): oral | 03/04/2023 | 22/05/2023 | Details | |
| N-butyl phenyl ether | 214-426-1 | 1126-79-0 | Long-term toxicity to fish | 03/04/2023 | 22/05/2023 | Details | |
| Octylphosphonic acid | 225-218-5 | 4724-48-5 | Sub-chronic toxicity (90-day): oral | 03/04/2023 | 22/05/2023 | Details | |
| Sodium p-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzenesulphonate | 223-989-2 | 4156-21-2 | Reproductive toxicity (pre-natal developmental toxicity) | 03/04/2023 | 22/05/2023 | Details | |
| tert-butyl peracetate | 203-514-5 | 107-71-1 | Genetic toxicity in vivo | 03/04/2023 | 22/05/2023 | Details | |
| Di-tert-butyl trisulphide | 224-226-6 | 4253-90-1 |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
01/03/2023 01/03/2023 01/03/2023 |
17/04/2023 17/04/2023 17/04/2023 |
Details | |
| 1,1'-[oxybis(ethyleneoxy)]diethylene | 212-133-3 | 764-99-8 |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) |
01/03/2023 01/03/2023 |
17/04/2023 17/04/2023 |
Details | |
| Amides, C16-C18 (even) , N,N'-ethylenebis | 931-299-4 | 68390-94-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
01/03/2023 01/03/2023 |
17/04/2023 17/04/2023 |
Details | |
| 3-methylpentane-1,5-diol | 224-709-1 | 4457-71-0 | Long-term toxicity to fish | 01/03/2023 | 17/04/2023 | Details | |
| [[(phosphonomethyl)imino]bis[ethylenenitrilobis(methylene)]]tetrakisphosphonic acid, ammonium salt | 274-798-6 | 70714-66-8 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Sodium salts of [[(phosphonomethyl)imino]bis[ethane-2,1-diylnitrilobis(methylene)]]tetrakisphosphonic acid (5-7 Na:1) (EC no. 701-216-4) | 01/03/2023 | 17/04/2023 | Details | |
| Xylene | 215-535-7 | 1330-20-7 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Reaction mass of ethylbenzene and xylene (EC No 905-588-0) | 01/03/2023 | 17/04/2023 | Details | |
| Zinc methacrylate | 236-144-8 | 13189-00-9 | Genetic toxicity in vivo | 01/03/2023 | 17/04/2023 | Details | |
| 7-hydroxycitronellal | 203-518-7 | 107-75-5 |
Sub-chronic toxicity (90-day): oral Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) |
31/01/2023 31/01/2023 31/01/2023 |
17/03/2023 17/03/2023 17/03/2023 |
Details | |
| Hexanoic acid, 3,5,5-trimethyl-, 2,2,6,6-tetramethyl-1-[2-[(3,5,5-trimethyl-1-oxohexyl)oxy]ethyl]-4-piperidinyl ester | 941-267-1 | 1445870-18-7 |
Long-term toxicity to fish Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) |
31/01/2023 31/01/2023 31/01/2023 |
17/03/2023 17/03/2023 17/03/2023 |
Details | |
| Alcohols, C13-15-branched and linear | 287-625-4 | 85566-16-1 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) |
31/01/2023 31/01/2023 |
17/03/2023 17/03/2023 |
Details | |
| 4,4'-Methylenediphenyl diisocyanate, oligomeric reaction products with 2,4'-diisocyanatodiphenylmethane | 500-297-1 | 109331-54-6 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) | 31/01/2023 | 17/03/2023 | Details | |
| Alkenes, C6-11 (branched), hydroformylation products, distn. residues, heavy cracked fraction | 701-314-7 | - | Reproductive toxicity (extended one-generation reproductive toxicity study) | 31/01/2023 | 17/03/2023 | Details | |
| alkoxy substituted aryl diazo heterocyclic aryl nitrile | - | - | Genetic toxicity in vivo | 31/01/2023 | 17/03/2023 | Details | |
| Dimethyl sulfoxide | 200-664-3 | 67-68-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 31/01/2023 | 17/03/2023 | Details | |
| Heptanoic acid | 203-838-7 | 111-14-8 | Long-term toxicity to fish | 31/01/2023 | 17/03/2023 | Details | |
| Mercaptoacetic acid | 200-677-4 | 68-11-1 | Long-term toxicity to fish | 31/01/2023 | 17/03/2023 | Details | |
| Reaction mass of 1,3-dioxane-5,5-dimethanol and 1,3-Propanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]- | 911-819-6 | - | Long-term toxicity to fish | 31/01/2023 | 17/03/2023 | Details | |
| Xylene | 215-535-7 | 1330-20-7 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Reaction mass of ethylbenzene and xylene (EC no. 905-588-0) | 31/01/2023 | 17/03/2023 | Details | |
| α-methyl-1,3-benzodioxole-5-propionaldehyde | 214-881-6 | 1205-17-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 31/01/2023 | 17/03/2023 | Details | |
| A mixture of cis- and trans-cyclohexadec-8-en-1-one | 401-700-2 | 3100-36-5 |
Long-term toxicity to fish Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) |
28/11/2022 28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 12/01/2023 |
Details | |
| Octanethioic acid, S-[3-(triethoxysilyl)propyl] ester, reaction products with 2-methyl-1,3-propanediol and 3-(triethoxysilyl)-1-propanethiol | 485-270-1 | - |
Long-term toxicity to fish Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) |
28/11/2022 28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 12/01/2023 |
Details | |
| 1-acetyl-4-(3-dodecyl-2,5-dioxo-1-pyrrolidinyl)-2,2,6,6-tetramethylpiperidine | 411-930-5 | - |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) |
28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 |
Details | |
| 2,4,8,10-Tetraoxaspiro[5.5]undecane-3,9-diethanol, .beta.3,.beta.3,.beta.9,.beta.9-tetramethyl- | 485-230-3 | - |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) |
28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 |
Details | |
| Alcohols, C6-8, ethoxylated | 800-182-9 | 1426148-68-6 |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) |
28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 |
Details | |
| dimethoxydimethylsilane | 214-189-4 | 1112-39-6 |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) |
28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 |
Details | |
| Neodecanoic acid, cobalt salt | 248-373-0 | 27253-31-2 | Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Neodecanoic acid, cobalt salt (EC no. 248-373-0) | 28/11/2022 | 12/01/2023 | Details | |
| Resin acids and Rosin acids, cobalt salts | 273-321-9 | 68956-82-1 | Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Neodecanoic acid, cobalt salt (EC no. 248-373-0) | 28/11/2022 | 12/01/2023 | Details | |
| Stearic acid, cobalt salt | 237-016-4 | 13586-84-0 | Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Neodecanoic acid, cobalt salt (EC no. 248-373-0) | 28/11/2022 | 12/01/2023 | Details | |
| Tris(2,4-ditert-butylphenyl) phosphite | 250-709-6 | 31570-04-4 | Reproductive toxicity (pre-natal developmental toxicity) | 28/11/2022 | 12/01/2023 | Details | |
| 1,4-diazabicyclooctane | 205-999-9 | 280-57-9 |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/10/2022 26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 12/12/2022 |
Details | |
| Petroleum diesel/gas oil fraction, co-processed with renewable hydrocarbons derived from thermally cracked plastics | 941-803-4 | - |
Sub-chronic toxicity (90-day): oral||Note: testing proposed with Gas oils (petroleum), light vacuum (EC no. 265-059-9) Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Gas oils (petroleum), light vacuum (EC no. 265-059-9) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Gas oils (petroleum), light vacuum (EC no. 265-059-9)
||Note: testing proposed with Fuels, diesel (EC no. 269-822-7)
||Note: testing proposed with Fuel oil, no. 4 (EC no. 270-673-5)
||Note: testing proposed with Distillates (petroleum), light hydrocracked (EC no. 265-078-2) |
26/10/2022 26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 12/12/2022 |
Details | |
| (2E)-2-ethyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)but-2-en-1-ol | 701-122-3 | 106185-75-5 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 |
Details | |
| (3-chloropropyl)triethoxysilane | 225-805-6 | 5089-70-3 |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) |
26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 |
Details | |
| 2-phosphonobutane-1,2,4-tricarboxylic acid | 253-733-5 | 37971-36-1 |
Long-term toxicity to fish||Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3) |
26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 |
Details | |
| Hexamethylcyclotrisiloxane | 208-765-4 | 541-05-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 |
Details | |
| Methyl benzoylformate | 239-263-3 | 15206-55-0 |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) |
26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 |
Details | |
| Poly[oxy(methyl-1,2-ethanediyl)], .alapha.,α'-(2,2-dimethyl-1,3-propanediyl)bis[ω-[(1-oxo-2-propenyl)oxy | 701-440-2 | - |
Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) |
26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 |
Details | |
| (2-ethyl-2-methyl-1,3-dioxolan-4-yl)methyl prop-2-enoate | 807-159-2 | 69701-99-1 | Genetic toxicity in vivo | 26/10/2022 | 12/12/2022 | Details | |
| 2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate | 239-701-3 | 15625-89-5 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/10/2022 | 12/12/2022 | Details | |
| 2-methylpropan-1-ol | 201-148-0 | 78-83-1 | Long-term toxicity to fish ||Note: testing proposed with Propan-1-ol (EC no. 200-746-9) ||Note: testing proposed with Pentan-1-ol (EC no. 200-752-1) | 26/10/2022 | 12/12/2022 | Details | |
| 3-(diethylamino)-7-oxo-7H-[1]benzopyrano[3',2':3,4]pyrido[1,2-a]benzimidazole-6-carbonitrile | 257-884-8 | 52372-36-8 | Genetic toxicity in vivo | 26/10/2022 | 12/12/2022 | Details | |