Previous Testing Proposals

Previous Testing Proposals

Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

There are currently no ongoing consultations.
 
1,3-diphenylguanidine 203-002-1 102-06-7 Long-term toxicity to fish 15/04/2011 30/05/2011 Details
1,5-Diisocyanatopentane 807-040-5 4538-42-5 Long-term toxicity to fish 30/06/2023 14/08/2023 Details
11-aminoundecanoic acid 219-417-6 2432-99-7 Long-term toxicity to fish 03/10/2023 17/11/2023 Details
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol] 245-509-0 23235-61-2 Long-term toxicity to fish 15/01/2024 29/02/2024 Details
2,2'-isopropylidenebis(p-phenyleneoxy)diethanol 212-985-6 901-44-0 Long-term toxicity to fish 22/09/2022 07/11/2022 Details
2,6-dimethyloct-7-en-2-ol 242-362-4 18479-58-8 Long-term toxicity to fish 03/10/2023 17/11/2023 Details
2-ethylhexyl acrylate 203-080-7 103-11-7 Long-term toxicity to fish 03/10/2023 17/11/2023 Details
2-Hydroxy-5-nonyl(branched)-benzaldehyde oxime 605-717-8 174333-80-3 Long-term toxicity to fish 22/06/2017 07/08/2017 Details
2-methyl-1,3-propanediol 412-350-5 2163-42-0 Long-term toxicity to fish 15/01/2024 29/02/2024 Details
2-methylpentane-2,4-diol 203-489-0 107-41-5 Long-term toxicity to fish 01/04/2022 16/05/2022 Details
2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs. 308-760-8 98246-87-8 Long-term toxicity to fish 22/09/2022 07/11/2022 Details
3-ethyloxetane-3-methanol 221-254-0 3047-32-3 Long-term toxicity to fish 03/10/2023 17/11/2023 Details
3-methoxy-3-methylbutan-1-ol 260-252-4 56539-66-3 Long-term toxicity to fish 26/10/2022 12/12/2022 Details
3-methylpentane-1,5-diol 224-709-1 4457-71-0 Long-term toxicity to fish 01/03/2023 17/04/2023 Details
4,4'-isopropylidenedicyclohexanol 201-244-2 80-04-6 Long-term toxicity to fish 17/06/2014 01/08/2014 Details
4,4'-sulphonyldiphenol 201-250-5 80-09-1 Long-term toxicity to fish 16/06/2022 01/08/2022 Details
4,8-Dimethyl-2,5,7,10-tetraoxaundecane 813-999-0 59039-15-5 Long-term toxicity to fish 30/06/2023 14/08/2023 Details
4-methylpentan-2-one 203-550-1 108-10-1 Long-term toxicity to fish 06/06/2023 21/07/2023 Details
5,5'-dithiodi-1,3,4-thiadiazole-2(3H)-thione 276-763-0 72676-55-2 Long-term toxicity to fish 30/06/2023 14/08/2023 Details
6-tert-butyl-2,4-xylenol 217-533-1 1879-09-0 Long-term toxicity to fish 15/07/2014 29/08/2014 Details
[3aR-(3aα,5aβ,9aα,9bβ)]-dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan 229-861-2 6790-58-5 Long-term toxicity to fish 22/09/2022 07/11/2022 Details
Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide 271-794-6 68608-66-2 Long-term toxicity to fish 18/02/2014 04/04/2014 Details
Androst-4-ene-3,17-dione 200-554-5 63-05-8 Long-term toxicity to fish 21/01/2021 08/03/2021 Details
Aziridine 205-793-9 151-56-4 Long-term toxicity to fish 26/01/2011 14/03/2011 Details
Barium carbonate 208-167-3 513-77-9 Long-term toxicity to fish 29/04/2011 14/06/2011 Details
Barium hydroxide 241-234-5 17194-00-2 Long-term toxicity to fish 29/04/2011 14/06/2011 Details
Barium sulfate 231-784-4 7727-43-7 Long-term toxicity to fish 29/04/2011 14/06/2011 Details
benzenesulfonic acid, 4-c10-13-alkyl derivs.-, salts with amines, c16-c18 (even numbered) alkyl 953-378-2 - Long-term toxicity to fish 30/09/2021 15/11/2021 Details
benzenesulfonic acid, mono- and dialkylation products with c16-20 (even numbered, branched and linear) olefins, calcium salts, calcium carbonate, overbased, including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic c15-c50 701-356-6 - Long-term toxicity to fish 22/04/2021 07/06/2021 Details
Benzyldimethylamine 203-149-1 103-83-3 Long-term toxicity to fish 06/06/2023 21/07/2023 Details
Bis(dibutyldithiocarbamato-S,S')copper 237-695-7 13927-71-4 Long-term toxicity to fish 22/06/2017 07/08/2017 Details
Bisdecanoyl peroxide 212-092-1 762-12-9 Long-term toxicity to fish 27/09/2017 13/11/2017 Details
Carboxymethyldimethyl-3-[[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulphonyl]amino]propylammonium hydroxide 252-046-8 34455-29-3 Long-term toxicity to fish 03/10/2023 17/11/2023 Details
Di-tert-butyl trisulphide 224-226-6 4253-90-1 Long-term toxicity to fish 30/06/2023 14/08/2023 Details
Dibutyl fumarate 203-327-9 105-75-9 Long-term toxicity to fish 16/05/2011 30/06/2011 Details
Dibutyl hydrogen phosphate 203-509-8 107-66-4 Long-term toxicity to fish 10/05/2022 27/06/2022 Details
Diethylmethylbenzenediamine 270-877-4 68479-98-1 Long-term toxicity to fish 04/12/2023 18/01/2024 Details
Dodecanoic acid, 2,2-dimethyl-3-oxopropyl ester 468-880-2 102985-93-3 Long-term toxicity to fish 30/09/2021 15/11/2021 Details
Esterification products of fatty acids, C18 (unsaturated) alkyl and adipic acid with pentaerythritol 952-795-7 - Long-term toxicity to fish 03/11/2023 18/12/2023 Details
Fatty acids, C16-18 and C18-unsatd., Et esters 285-206-0 85049-36-1 Long-term toxicity to fish 01/07/2011 15/08/2011 Details
Fatty acids, C18-unsatd., reaction products with diethylenetriamine 629-715-1 1226892-43-8 Long-term toxicity to fish 26/10/2022 12/12/2022 Details
Fatty acids, tall-oil, compds. with N-[3-(dimethylamino)propyl]tall-oil amides 295-714-4 92128-22-8 Long-term toxicity to fish 03/10/2023 17/11/2023 Details
Fatty acids, tall-oil, compds. with oleylamine 288-315-1 85711-55-3 Long-term toxicity to fish 04/04/2014 19/05/2014 Details
Fatty acids, tall-oil, reaction products with acrylic acid 939-424-4 - Long-term toxicity to fish 04/04/2014 19/05/2014 Details
Heptanoic acid 203-838-7 111-14-8 Long-term toxicity to fish 31/01/2023 17/03/2023 Details
Hexyl 2-(1-(diethylaminohydroxyphenyl)methanoyl)benzoate 443-860-6 302776-68-7 Long-term toxicity to fish 16/08/2011 30/09/2011 Details
Imidazolidine-2-thione 202-506-9 96-45-7 Long-term toxicity to fish 29/04/2011 14/06/2011 Details
Isononanoic acid, C16-18 (even numbered)-alkyl esters 601-141-6 111937-03-2 Long-term toxicity to fish 01/04/2022 16/05/2022 Details
Mercaptoacetic acid 200-677-4 68-11-1 Long-term toxicity to fish 31/01/2023 17/03/2023 Details
methyl acrylate; methyl propenoate 202-500-6 96-33-3 Long-term toxicity to fish 03/10/2023 17/11/2023 Details
Multi-Wall Carbon Nanotubes, synthetic graphite in tubular shape 231-955-3 7782-42-5 Long-term toxicity to fish 03/11/2011 19/12/2011 Details
N,N-dimethyldecan-1-amide 238-405-1 14433-76-2 Long-term toxicity to fish 15/07/2011 29/08/2011 Details
N-(2-nitrophenyl)phosphoric triamide 477-690-9 - Long-term toxicity to fish 18/03/2021 03/05/2021 Details
N-butyl phenyl ether 214-426-1 1126-79-0 Long-term toxicity to fish 03/04/2023 22/05/2023 Details
Naphthenic acids 215-662-8 1338-24-5 Long-term toxicity to fish 01/07/2011 15/08/2011 Details
Oxydipropyl dibenzoate 248-258-5 27138-31-4 Long-term toxicity to fish 10/08/2018 24/09/2018 Details
p-cresol 203-398-6 106-44-5 Long-term toxicity to fish 10/05/2022 27/06/2022 Details
Pentaerythritol 204-104-9 115-77-5 Long-term toxicity to fish 03/05/2023 19/06/2023 Details
Pentaerythritol tetrakis(3-mercaptopropionate) 231-472-8 7575-23-7 Long-term toxicity to fish 01/07/2021 16/08/2021 Details
Polyamide wax 434-430-9 - Long-term toxicity to fish 07/07/2020 21/08/2020 Details
potassium titanium oxide (K2Ti6O13) 432-240-0 12056-51-8 Long-term toxicity to fish 17/05/2017 03/07/2017 Details
Prop-2-yn-1-ol 203-471-2 107-19-7 Long-term toxicity to fish 22/09/2022 07/11/2022 Details
Reaction mass of 1,3-dioxane-5,5-dimethanol and 1,3-Propanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]- 911-819-6 - Long-term toxicity to fish 31/01/2023 17/03/2023 Details
Reaction mass of 2-ethyl-2-(methoxymethyl)-propane-1,3-diol and 2-ethylpropane-1,3-diol 938-572-7 - Long-term toxicity to fish 22/09/2022 07/11/2022 Details
Reaction mass of ethoxylated (= 3 moles) bisphenol A dimethacrylate and (1-methylethylidene)bis(4,1-phenyleneoxy-2,1-ethanediyl) bismethacrylate 939-702-5 - Long-term toxicity to fish 25/11/2019 09/01/2020 Details
reaction products of 1,4-butanediol with 1,3-chloro-2,3-epoxypropane, esters with prop-2-enoic acid 701-230-0 - Long-term toxicity to fish 10/05/2022 27/06/2022 Details
Reaction products of n-octanol and acrylic acid, first distillation pitch 938-925-5 - Long-term toxicity to fish 15/01/2024 29/02/2024 Details
Reaction products of tetrazotized 5-amino-2-[(E)-2-(4-amino-2-sulfophenyl)ethenyl]benzenesulfonic acid with 6-amino-4-hydroxynaphthalene-2-sulfonic acid and 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid in 2-[bis(2-hydroxyethyl)amino]ethanol 916-899-6 - Long-term toxicity to fish 25/11/2021 10/01/2022 Details
Silsesquioxanes, phenyl - 70131-69-0 Long-term toxicity to fish 18/09/2014 03/11/2014 Details
Strontium carbonate 216-643-7 1633-05-2 Long-term toxicity to fish 31/05/2011 15/07/2011 Details
Strontium chromate 232-142-6 7789-06-2 Long-term toxicity to fish 31/05/2011 15/07/2011 Details
Styrene 202-851-5 100-42-5 Long-term toxicity to fish 30/06/2023 14/08/2023 Details
Styrene 202-851-5 100-42-5 Long-term toxicity to fish 04/09/2023 19/10/2023 Details
SUMILIZER GP 442-450-4 - Long-term toxicity to fish 25/11/2021 10/01/2022 Details
tert-butyl perbenzoate 210-382-2 614-45-9 Long-term toxicity to fish 23/03/2020 07/05/2020 Details
tert-dodecanethiol 246-619-1 25103-58-6 Long-term toxicity to fish 16/06/2022 01/08/2022 Details
Tetramethylammonium hydroxide 200-882-9 75-59-2 Long-term toxicity to fish 30/06/2023 14/08/2023 Details
Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarboxylate 266-442-3 66669-53-2 Long-term toxicity to fish 22/09/2022 07/11/2022 Details
trimethoxy(2,4,4-trimethylpentyl)silane 251-995-5 34396-03-7 Long-term toxicity to fish 26/10/2022 12/12/2022 Details
Trimethylolpropane and its reaction products with methyloxirane 957-630-2 - Long-term toxicity to fish 15/01/2024 29/02/2024 Details
Triphenylphosphine 210-036-0 603-35-0 Long-term toxicity to fish 03/10/2023 17/11/2023 Details
undec-10-enoic acid 203-965-8 112-38-9 Long-term toxicity to fish 16/10/2014 01/12/2014 Details
Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl 905-837-3 - Long-term toxicity to fish || Note: substance forms part of category; testing is also proposed with Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI), Octylamine and Hexamethylenediamine (EC no. 923-615-4) 26/08/2021 11/10/2021 Details
Reaction products of C18 (unsaturated) fatty acids and dimethyl sulfate and triethanolamine 931-216-1 - Long-term toxicity to fish || Note: testing proposed with Fatty acids, C16-18 (even numbered) and C18 unsatd., reaction products with diethylene triamine, di-Me sulfate quaternized (EC 937-237-2) 22/04/2021 07/06/2021 Details
Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (101-68-8), Octylamine (111-86-4) and Cyclohexylamine (108-91-8) 926-119-6 - Long-term toxicity to fish || Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (CAS: 101-68-8), Octylamine (111-86-4) and Hexamethylenediamine (124-09-4) (EC no 924-670-7) 30/09/2021 15/11/2021 Details
1-Dodecanamine, reaction products with 1,1'-methylenebis[4-isocyanatobenzene] and 1-octanamine 812-490-0 1312943-21-7 Long-term toxicity to fish || Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (Octylamine and Hexamethylenediamine (EC no. 924-670-7) 26/08/2021 11/10/2021 Details
1-Octadecanamine, reaction products with 1,1'-methylenebis[4-isocyanatobenzene] and 1-octanamine 812-491-6 1312943-23-9 Long-term toxicity to fish || Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) , Octylamine) and Hexamethylenediamine (EC no. 924-670-7) 26/08/2021 11/10/2021 Details
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-C13 odd-numbered alkyl) derivs. and sodium hydroxide and chloroacetic acid 938-645-3 -
Long-term toxicity to fish Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11 alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 271-794-6)
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0)
Sub-chronic toxicity (90-day): oral Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0)
16/03/2015
16/03/2015
16/03/2015
30/04/2015
30/04/2015
30/04/2015
Details
Reaction mass of 2,4,6,8,10-pentamethyl-2,4,6,8,10-pentavinylcyclopentasiloxane and 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane 911-381-6 - Long-term toxicity to fish || Note: testing proposed with 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane (EC 219-863-1) || Note: Testing proposal is based on concern identified by the registrant 17/06/2020 03/08/2020 Details
Triethoxyoctylsilane 220-941-2 2943-75-1 Long-term toxicity to fish || Note: testing proposed with Triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1) 17/04/2015 04/06/2015 Details
2-methylpropan-1-ol 201-148-0 78-83-1 Long-term toxicity to fish ||Note: testing proposed with Propan-1-ol (EC no. 200-746-9) ||Note: testing proposed with Pentan-1-ol (EC no. 200-752-1) 26/10/2022 12/12/2022 Details
Strontium hydroxide 242-367-1 18480-07-4
Long-term toxicity to fish Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9)
Reproductive toxicity (pre-natal developmental toxicity) Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9)
Reproductive toxicity (two-generation reproductive toxicity) Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9)
15/04/2014
15/04/2014
15/04/2014
30/05/2014
30/05/2014
30/05/2014
Details
Benzyltoluene 248-654-8 27776-01-8 Long-term toxicity to fish (OECD 210) 25/06/2019 09/08/2019 Details
Fatty acids, C12-14, α-sulfo, disodium salts 942-523-5 -
Long-term toxicity to fish (OECD 212 – Registrant’s preference)
Reproductive toxicity (pre-natal developmental toxicity) on rodents
Sub-chronic toxicity (90-day): oral on rodents
25/06/2019
25/06/2019
25/06/2019
09/08/2019
09/08/2019
09/08/2019
Details
Fatty acids, C16-18, barium salts 292-883-6 91002-07-2 Long-term toxicity to fish //Note: testing to be done with barium dichloride (CAS number 10361-37-2) 04/04/2014 19/05/2014 Details
2,4,7,9-tetramethyl-4,7-decanediol 451-160-7 17913-76-7
Long-term toxicity to fish
"|| Note: testing proposed with 2,4,7,9-tetramethyldec-5-yne-4,7-diol (EC 204-809-1, CAS 126-86-3)
Reproductive toxicity (pre-natal developmental toxicity)
17/09/2019
17/09/2019
01/11/2019
01/11/2019
Details
Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide 271-794-6 68608-66-2 Long-term toxicity to fish Sub-chronic toxicity (90-day): oral || Note: testing proposed with Reaction products of 1H-Imidazole- 1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0) Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0 29/02/2016 14/04/2016 Details
benzyl butyl cis-cyclohexane-1,2-dicarboxylate 701-279-8 1931129-39-3
Long-term toxicity to fish || Note: Link to the registration dossier not given as the dossier not yet disseminated. || Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5
Reproductive toxicity (pre-natal developmental toxicity) || Note: Link to registration dossier not given as the dossier not yet disseminated. || Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5
Sub-chronic toxicity (90-day): oral || Note: Link to registration dossier not given as the dossier not yet disseminated. || Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5
10/12/2018
10/12/2018
10/12/2018
24/01/2019
24/01/2019
24/01/2019
Details
1,1,4,4-tetramethylbutane-1,4-diyl bis(2-ethylperoxyhexanoate) 235-935-5 13052-09-0 Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates 12/12/2014 26/01/2015 Details
2-ethyl-2-[[(1-oxononyl)oxy]methyl]propane-1,3-diyl dinonan-1-oate 204-793-6 126-57-8 Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates 17/04/2015 04/06/2015 Details
bis(piperidinothiocarbonyl) hexasulphide 213-537-2 971-15-3 Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates 16/02/2015 02/04/2015 Details
tert-butyl α,α-dimethylbenzyl peroxide 222-389-8 3457-61-2 Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates 16/03/2015 30/04/2015 Details
N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan-1-amide) 204-613-6 123-26-2
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with: “Octadecanoic acid, 12-hydroxy-, reaction products with ethylenediamine”, CAS 100545-48-0
Sub-chronic toxicity (90 day): oral
30/09/2015
30/09/2015
30/09/2015
16/11/2015
16/11/2015
16/11/2015
Details
Fats and Glyceridic oils, vegetable, winterized, reaction products with ammonia-ethanolamine reaction products 800-253-4 - Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates.

Link to registration dossier not given as the dossier not yet disseminated.
30/11/2015 14/01/2016 Details
Triethoxy(2,4,4-trimethylpentyl)silane 252-558-1 35435-21-3
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates.
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1)
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Details
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-C12-14 acyl derivs., hydroxides, inner salts 293-878-1 91648-19-0
Long-term toxicity to fish || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-457-4)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3)
18/06/2018
18/06/2018
18/06/2018
02/08/2018
02/08/2018
02/08/2018
Details
Reaction product of 4,4'-methylenediphenyl diisocyanate, Octylamine and Hexamethylenediamine 924-670-7 - Long-term toxicity to fish || Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) 16/06/2022 01/08/2022 Details
2-Oxetanone, 3-C12-16-alkyl-4-C13-17-alkylidene derivs., (4E)- 939-401-9 1469983-41-2 Long-term toxicity to fish ||Note: testing proposed with 2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs (EC no. 308-760-8) 15/07/2022 29/08/2022 Details
Heptan-1-ol 203-897-9 111-70-6
Long-term toxicity to fish
Long-term toxicity to fish
Sub-chronic toxicity (90 day): Oral
04/09/2012
18/02/2014
04/09/2012
19/10/2012
04/04/2014
19/10/2012
Details
Alcohols, C13-15-branched and linear 287-625-4 85566-16-1
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
31/01/2023
31/01/2023
17/03/2023
17/03/2023
Details
Bis(2-ethylhexyl) adipate 203-090-1 103-23-1
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
01/04/2022
01/04/2022
16/05/2022
16/05/2022
Details
N,N-dimethyl-alkyl-1-amines, reaction products with alkali hydroxide and chloroacetic acid 939-682-8 -
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
10/05/2022
10/05/2022
27/06/2022
27/06/2022
Details
Octadecanoic acid, 12-hydroxy-, reaction products with decanoic acid and ethylenediamine 907-495-0 -
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
01/04/2022
01/04/2022
16/05/2022
16/05/2022
Details
N-octadecylstearamide 236-276-6 13276-08-9
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
17/04/2015
17/04/2015
17/04/2015
04/06/2015
04/06/2015
04/06/2015
Details
Phosphoric acid, octadecyl ester 254-466-7 39471-52-8
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/04/2015
17/04/2015
17/04/2015
17/04/2015
04/06/2015
04/06/2015
04/06/2015
04/06/2015
Details
5-ethyl-1,3-dioxane-5-methanol 225-967-8 5187-23-5
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
03/10/2023
03/10/2023
03/10/2023
17/11/2023
17/11/2023
17/11/2023
Details
Alcohols, C8-10, ethoxylated 615-247-5 71060-57-6
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
22/09/2022
22/09/2022
22/09/2022
07/11/2022
07/11/2022
07/11/2022
Details
Fatty acids, C8-10, C12-18-alkyl esters 306-082-7 95912-86-0
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/04/2022
01/04/2022
01/04/2022
16/05/2022
16/05/2022
16/05/2022
Details
Octyl octanoate 218-980-5 2306-88-9
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
03/04/2023
03/04/2023
03/04/2023
22/05/2023
22/05/2023
22/05/2023
Details
Reaction mass of 2-(1,1-dimethylpropyl)anthraquinone and 2-(1,2-dimethylpropyl)anthraquinonedimethylpropyl)anthraquinone 915-623-1 -
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
27/09/2017
27/09/2017
27/09/2017
13/11/2017
13/11/2017
13/11/2017
Details
12-hydroxystearic acid 203-366-1 106-14-9
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/10/2023
03/10/2023
03/10/2023
03/10/2023
17/11/2023
17/11/2023
17/11/2023
17/11/2023
Details
1,2-dihydroxybenzene,pyrocatechol 204-427-5 120-80-9
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
15/04/2011
15/04/2011
30/05/2011
30/05/2011
Details
6-tert-butyl-2,4-xylenol 217-533-1 1879-09-0
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
18/02/2021
18/02/2021
05/04/2021
05/04/2021
Details
Ethanol, 2,2'-iminobis-, N-(C13-15-branched and linear alkyl) derivs. 308-208-6 97925-95-6
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
29/07/2011
29/07/2011
12/09/2011
12/09/2011
Details
N,N’-di[3-(p-toluene sulfonyl)oxy]phenyl urea 876-151-9 2292123-68-1
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
03/04/2023
03/04/2023
22/05/2023
22/05/2023
Details
Oleic acid, compound with (Z)-N-octadec-9-enylpropane-1,3-diamine (2:1) 251-846-4 34140-91-5
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
10/05/2022
10/05/2022
27/06/2022
27/06/2022
Details
tert-butyl perbenzoate 210-382-2 614-45-9
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
16/06/2011
16/06/2011
01/08/2011
01/08/2011
Details
Thymol 201-944-8 89-83-8
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
16/06/2022
16/06/2022
01/08/2022
01/08/2022
Details
2,4,8,10-tetra(tert-butyl)-6-hydroxy-12H-dibenzo[d,g][1,3,2]dioxaphosphocin 6-oxide, sodium salt 286-344-4 85209-91-2
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/10/2014
16/10/2014
16/10/2014
01/12/2014
01/12/2014
01/12/2014
Details
4-tert-butylpyrocatechol 202-653-9 98-29-3
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
29/04/2011
29/04/2011
29/04/2011
14/06/2011
14/06/2011
14/06/2011
Details
Barium chloride 233-788-1 10361-37-2
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
29/04/2011
29/04/2011
29/04/2011
14/06/2011
14/06/2011
14/06/2011
Details
Strontium nitrate 233-131-9 10042-76-9
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
31/05/2011
31/05/2011
31/05/2011
15/07/2011
15/07/2011
15/07/2011
Details
Sulphamidic acid 226-218-8 5329-14-6
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
14/02/2011
14/02/2011
14/02/2011
31/03/2011
31/03/2011
31/03/2011
Details
Quaternary ammonium compounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, reaction products with polyethylenepolyamines and tall-oil fatty acids, humates hydrochlorides 272-745-1 68910-55-4
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
23/01/2015
23/01/2015
23/01/2015
23/01/2015
09/03/2015
09/03/2015
09/03/2015
09/03/2015
Details
2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine 426-040-2 25713-60-4
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
16/06/2011
16/06/2011
16/06/2011
16/06/2011
01/08/2011
01/08/2011
01/08/2011
01/08/2011
Details
2-Butenedioic acid (Z)-, ester with 1,2-propanediol, compd. with 2-(dibutylamino)ethanol 286-304-6 85204-10-0
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/06/2014
02/06/2014
02/06/2014
02/06/2014
17/07/2014
17/07/2014
17/07/2014
17/07/2014
Details
Fatty acids, tall-oil, reaction products with triethanolamine 267-053-1 67784-78-5
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
29/07/2011
29/07/2011
29/07/2011
29/07/2011
12/09/2011
12/09/2011
12/09/2011
12/09/2011
Details
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts 939-455-3 -
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): oral
18/09/2014
18/09/2014
18/09/2014
03/11/2014
03/11/2014
03/11/2014
Details
(octahydro-4,7-methano-1H-indenediyl)bis(methylene) diacrylate 255-901-3 42594-17-2
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
22/04/2021
22/04/2021
22/04/2021
07/06/2021
07/06/2021
07/06/2021
Details
1,3,5-tris(2,3-dibromopropyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione 257-913-4 52434-90-9
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/04/2023
03/04/2023
03/04/2023
22/05/2023
22/05/2023
22/05/2023
Details
1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)carbamate 411-700-4 140921-24-0
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/05/2022
10/05/2022
10/05/2022
27/06/2022
27/06/2022
27/06/2022
Details
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts 939-457-4 -
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/09/2014
18/09/2014
18/09/2014
03/11/2014
03/11/2014
03/11/2014
Details
3-hydroxy-1,1-dimethylbutyl 2-ethyl-2-methylheptaneperoxoate 413-910-1 95718-78-8
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/04/2012
17/04/2012
17/04/2012
01/06/2012
01/06/2012
01/06/2012
Details
4,4'-oxydi(benzenesulphonohydrazide) 201-286-1 80-51-3
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/03/2014
21/03/2014
21/03/2014
05/05/2014
05/05/2014
05/05/2014
Details
4,4`-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with methacrylic acid 500-089-0 36425-15-7
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
01/07/2011
01/07/2011
01/07/2011
15/08/2011
15/08/2011
15/08/2011
Details
A dried sludge product resulting from the treatment process of domestic wastewater. The exact processes followed for the production of the dried sludge are: Preliminary and secondary treatment of the wastewater stream, thickening, dehydration and drying of the excess sludge. 943-834-9 -
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/04/2023
03/04/2023
03/04/2023
22/05/2023
22/05/2023
22/05/2023
Details
A mixture of cis- and trans-cyclohexadec-8-en-1-one 401-700-2 3100-36-5
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
28/11/2022
28/11/2022
28/11/2022
12/01/2023
12/01/2023
12/01/2023
Details
Condensation products of triethanolamine with addition products of fatty acids, C18 (unsaturated) alkyl with maleic anhydride - -
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/03/2017
10/03/2017
10/03/2017
25/04/2017
25/04/2017
25/04/2017
Details
Di-tert-butyl peroxide 203-733-6 110-05-4
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
01/07/2011
01/07/2011
01/07/2011
15/08/2011
15/08/2011
15/08/2011
Details
Diphosphoric acid, compd. with piperazine (1:1) 457-330-7 66034-17-1
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/05/2022
10/05/2022
10/05/2022
27/06/2022
27/06/2022
27/06/2022
Details
Fatty acids, C12-18 (even numbered)-methyl esters, sulfonated, sodium salts 947-394-9 -
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
19/10/2020
19/10/2020
19/10/2020
03/12/2020
03/12/2020
03/12/2020
Details
Fatty acids, C14-18 and C16-18-unsatd., maleated - 85711-46-2
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
11/11/2016
11/11/2016
11/11/2016
03/01/2017
03/01/2017
03/01/2017
Details
Fatty acids, C16-18, isononyl esters 292-960-4 91031-57-1
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
30/06/2023
30/06/2023
30/06/2023
14/08/2023
14/08/2023
14/08/2023
Details
Hexanoic acid, 3,5,5-trimethyl-, 2,2,6,6-tetramethyl-1-[2-[(3,5,5-trimethyl-1-oxohexyl)oxy]ethyl]-4-piperidinyl ester 941-267-1 1445870-18-7
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2023
31/01/2023
31/01/2023
17/03/2023
17/03/2023
17/03/2023
Details
N-(2-hydroxypropyl)oleamide 203-828-2 111-05-7
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
14/08/2014
28/09/2014
28/09/2014
28/09/2014
Details
N1,N3‐bis(3‐methylphenyl)‐5‐[(3‐methylphenyl)sulfamoyl]benzene‐1,3‐dicarboxamide 951-483-8 2375645-78-4
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/06/2022
16/06/2022
16/06/2022
01/08/2022
01/08/2022
01/08/2022
Details
O-(2-ethylhexyl) O,O-tert-pentyl peroxycarbonate 274-919-2 70833-40-8
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/10/2023
03/10/2023
03/10/2023
17/11/2023
17/11/2023
17/11/2023
Details
Octanethioic acid, S-[3-(triethoxysilyl)propyl] ester, reaction products with 2-methyl-1,3-propanediol and 3-(triethoxysilyl)-1-propanethiol 485-270-1 -
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
28/11/2022
28/11/2022
28/11/2022
12/01/2023
12/01/2023
12/01/2023
Details
Reaction mass of [[(2-hydroxyethyl)imino]bis(methylene)]bisphosphonic acid and Phosphonic acid, P-[(tetrahydro-2-hydroxy-2-oxido-4H-1,4,2-oxazaphosphorin-4-yl)methyl]- 911-811-2 -
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/04/2015
17/04/2015
17/04/2015
04/06/2015
04/06/2015
04/06/2015
Details
Sodium hydroxymethanesulphinate 205-739-4 149-44-0
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2011
15/04/2011
15/04/2011
30/05/2011
30/05/2011
30/05/2011
Details
Tetrakis(phenylmethyl)thioperoxydi(carbothioamide) 404-310-0 10591-85-2
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
30/09/2021
30/09/2021
30/09/2021
15/11/2021
15/11/2021
15/11/2021
Details
Aluminum triformate 230-898-1 7360-53-4
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity study (90-day): oral
21/01/2011
21/01/2011
21/01/2011
07/03/2011
07/03/2011
07/03/2011
Details
1,10-decanediyl diacrylate 235-922-4 13048-34-5
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Esterification products of acrylic acid with reaction products of 2,2-dimethylpropane-1,3-diol and methyloxirane (EC no. 701-440-2)
Sub-chronic toxicity (90-day): oral||Note: testing proposed with Esterification products of acrylic acid with reaction products of 2,2-dimethylpropane-1,3-diol and methyloxirane (EC no. 701-440-2)
06/06/2023
06/06/2023
06/06/2023
21/07/2023
21/07/2023
21/07/2023
Details
Pentane-2,4-dione 204-634-0 123-54-6
Long-term toxicity to fish
Reproductive toxicity (two-generation reproductive toxicity)
15/07/2011
15/07/2011
29/08/2011
29/08/2011
Details
di(morpholin-4-yl) disulphide 203-103-0 103-34-4
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
29/04/2011
29/04/2011
14/06/2011
14/06/2011
Details
Ethyl 4-dimethylaminobenzoate 233-634-3 10287-53-3
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
10/05/2022
10/05/2022
27/06/2022
27/06/2022
Details
Isodecyl methacrylate 249-978-2 29964-84-9
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
03/10/2023
03/10/2023
17/11/2023
17/11/2023
Details
Reaction mass of Amides, rape-oil, N-(hydroxyethyl), ethoxylated and Glycerol, ethoxylated 932-164-2 -
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
29/07/2011
29/07/2011
12/09/2011
12/09/2011
Details
N,N'-(methylenedi-p-phenylene)bis[hexahydro-2-oxo-1H-azepine-1-carboxamide] 258-981-8 54112-23-1 Long-term toxicity to fish
Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates.
31/08/2015 15/10/2015 Details
m-cresol 203-577-9 108-39-4 Long-term toxicity to fish|| Note: testing proposed with p-cresol (EC no. 203-398-6) 10/05/2022 27/06/2022 Details
Diisononyl adipate 251-646-7 33703-08-1
Long-term toxicity to fish||Note: Read across testing proposed with Bis(2-ethylhexyl) adipate (EC no. 203-090-1)
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: Read across testing proposed with Bis(2-ethylhexyl) adipate (EC no. 203-090-1)
03/05/2023
03/05/2023
19/06/2023
19/06/2023
Details
3-trimethoxysilylpropane-1-thiol 224-588-5 4420-74-0 Long-term toxicity to fish||Note: testing proposed with 3-Triethoxysilylpropane-1-thiol (EC no. 238-883-1) 22/09/2022 07/11/2022 Details
Benzenesulfonic acid, mono- and dialkylation products with C16-20 (even numbered, branched and linear) olefins, magnesium salts, magnesium carbonate, overbased, including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic C15-C50 701-469-0 - Long-term toxicity to fish||Note: testing proposed with Benzenesulfonic acid, mono- and dialkylation products with C16-20 (even numbered, branched and linear) olefins, calcium salts, calcium carbonate, overbased, including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic C15-C50 (EC no. 701-356-6) 04/09/2023 19/10/2023 Details
C18 unsaturated fatty acids, reaction products with 1-aminopropan-2-ol, maleic anhydride and sodium bisulfite 947-655-7 - Long-term toxicity to fish||Note: testing proposed with disodium 4-[1-methyl-2-[(1-oxooctadec-9-enyl)amino]ethyl] 2-sulphonatosuccinate (EC no. 267-199-6) 15/01/2024 29/02/2024 Details
A mixture of: triphenylthiophosphate and tertiary butylated phenyl derivatives 421-820-9 192268-65-8 Long-term toxicity to fish||Note: testing proposed with O,O,O-triphenyl phosphorothioate (EC no. 209-909-9) 04/12/2023 18/01/2024 Details
o-cresol 202-423-8 95-48-7 Long-term toxicity to fish||Note: testing proposed with p-cresol (EC no. 203-398-6) 10/05/2022 27/06/2022 Details
3-methylbutan-1-ol 204-633-5 123-51-3 Long-term toxicity to fish||Note: testing proposed with Pentan-1-ol (EC no. 200-752-1) 22/09/2022 07/11/2022 Details
2-phosphonobutane-1,2,4-tricarboxylic acid 253-733-5 37971-36-1
Long-term toxicity to fish||Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3)
26/10/2022
26/10/2022
12/12/2022
12/12/2022
Details
Cyclohexane-1,4-diyldimethanol 203-268-9 105-08-8 OECD Guideline 414 (Prenatal Developmental Toxicity Study) 19/11/2010 03/01/2011 Details
Reaction mass of resin acids and rosin acids, hydrogenated, potassium salts and potassium [1R-(1a,4aß,10aa)]-1,2,3,4,4a,9,10,10a-octahydro-7-isopropyl-1,4a-dimethylphenanthren-1-carboxylate 915-657-7 -
Pre-natal developmental toxicity, //Note: Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8)
Two-generation reproductive toxicity, //Note: Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8)
19/07/2013
19/07/2013
02/09/2013
02/09/2013
Details
Reaction mass of resin acids and rosin acids, hydrogenated, sodium salts and sodium [1R-(1a,4aß,10aa)]-1,2,3,4,4a,9,10,10a-octahydro-7- -isopropyl-1,4a-dimethylphenanthren-1-carboxylate 915-568-3 -
Pre-natal developmental toxicity, //Note: Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8)
Two-generation reproductive toxicity, //Note: Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8)
19/07/2013
19/07/2013
02/09/2013
02/08/2013
Details
Orthoboric acid, compound with 2-aminoethanol 247-421-8 26038-87-9 Repeated dose toxicity (90-day): oral 17/11/2011 02/01/2012 Details
12-hydroxyoctadecanoic acid, reaction products with 1,3-benzenedimethanamine and hexamethylenediamine 432-840-2 220926-97-6 Repeated dose toxicity: Inhalation 04/05/2010 18/06/2010 Details
4,4'-methylenebis[N,N-bis(2,3-epoxypropyl)aniline] 249-204-3 28768-32-3
Reproduction toxicity (two generation reproductive toxicity)
Reproductive toxicity (developmental toxicity)
Sub-chronic toxicity (90-day): dermal
26/01/2011
26/01/2011
26/01/2011
14/03/2011
14/03/2011
14/03/2011
Details
1,6-Bis((dibenzylthiocarbamoyl)disulfanyl)hexane 429-280-6 151900-44-6 Reproductive toxicity (developmental toxicity) 01/09/2010 15/10/2010 Details
11-aminoundecanoic acid 219-417-6 2432-99-7 Reproductive toxicity (developmental toxicity) 08/04/2010 24/05/2010 Details
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol] 245-509-0 23235-61-2 Reproductive toxicity (developmental toxicity) 26/01/2011 14/03/2011 Details
3-amino-4-octanol  482-070-6 1001354-72-8 Reproductive toxicity (developmental toxicity) 19/11/2010 03/01/2011 Details
Sodium phosphinate 231-669-9 7681-53-0 Reproductive toxicity (developmental toxicity) 26/01/2011 14/03/2011 Details
Hydrogenated oligomerisation product, including dimers and trimers, of tetradec-1-ene and alkene - -
Reproductive toxicity (developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
10/08/2009
10/08/2009
24/09/2009
24/09/2009
Details
2,3-epoxypropyl neodecanoate 247-979-2 26761-45-5
Reproductive toxicity (developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day)
26/05/2010
26/05/2010
26/05/2010
12/07/2010
12/07/2010
12/07/2010
Details
4-((Triethoxysilyl)methyl) morpholine 480-370-1 21743-27-1
Reproductive toxicity (developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day)
27/11/2009
27/11/2009
27/11/2009
11/01/2010
11/01/2010
11/01/2010
Details
3-Sulfanylpropanoic acid 203-537-0 107-96-0
Reproductive toxicity (developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
05/04/2011
05/04/2011
05/04/2011
20/05/2011
20/05/2011
20/05/2011
Details
Mono- and/or di- and/or tri(1-phenylethyl)-m-cresol and p-cresol 700-427-9 -
Reproductive toxicity (developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
01/12/2010
01/12/2010
01/12/2010
17/01/2011
17/01/2011
17/01/2011
Details
Dimethylpropane-1,3-diol 204-781-0 126-30-7
Reproductive toxicity (developmental toxicity)
Sub-chronic toxicity (90-day)
26/01/2011
26/01/2011
14/03/2011
14/03/2011
Details
1,5-bis[1,2-bis(ethoxycarbonyl)ethylamino]-2-methylpentane 433-260-2 168253-59-6
Reproductive toxicity (developmental toxicity)
Sub-chronic toxicity (90-day): oral
06/09/2010
06/09/2010
20/10/2010
20/10/2010
Details
Reaction mass of 1,3-Propanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]- and 1,3-dioxane-5,5-dimethanol 911-819-6 -
Reproductive toxicity (developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/02/2011
14/02/2011
31/03/2011
31/03/2011
Details
Tri-C18-22 (even numbered)-alkyl 2-hydroxypropane-1,2,3-tricarboxylate 700-316-5 -
Reproductive toxicity (developmental toxicity)
Sub-chronic toxicity (90-days): oral
11/01/2011
11/01/2011
25/02/2011
25/02/2011
Details
Reaction mass of disodium hydroxysulfinatoacetate and disodium hydroxysulfonatoacetate - -
Reproductive toxicity (developmental toxicity)
Sub-chronic toxicity study (90-day): oral
13/12/2010
13/12/2010
27/01/2011
27/01/2011
Details
Dodecamethylcyclohexasiloxane 208-762-8 540-97-6 Reproductive toxicity (extended one-generation reproductive toxicity study 23/04/2018 07/06/2018 Details