Previous Testing Proposals
Previous Testing Proposals
Previous Testing Proposals
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
1,3-diphenylguanidine | 203-002-1 | 102-06-7 | Long-term toxicity to fish | 15/04/2011 | 30/05/2011 | Details | |
1,5-Diisocyanatopentane | 807-040-5 | 4538-42-5 | Long-term toxicity to fish | 30/06/2023 | 14/08/2023 | Details | |
11-aminoundecanoic acid | 219-417-6 | 2432-99-7 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol] | 245-509-0 | 23235-61-2 | Long-term toxicity to fish | 15/01/2024 | 29/02/2024 | Details | |
2,2'-isopropylidenebis(p-phenyleneoxy)diethanol | 212-985-6 | 901-44-0 | Long-term toxicity to fish | 22/09/2022 | 07/11/2022 | Details | |
2,6-dimethyloct-7-en-2-ol | 242-362-4 | 18479-58-8 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
2-ethylhexyl acrylate | 203-080-7 | 103-11-7 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
2-Hydroxy-5-nonyl(branched)-benzaldehyde oxime | 605-717-8 | 174333-80-3 | Long-term toxicity to fish | 22/06/2017 | 07/08/2017 | Details | |
2-methyl-1,3-propanediol | 412-350-5 | 2163-42-0 | Long-term toxicity to fish | 15/01/2024 | 29/02/2024 | Details | |
2-methylpentane-2,4-diol | 203-489-0 | 107-41-5 | Long-term toxicity to fish | 01/04/2022 | 16/05/2022 | Details | |
2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs. | 308-760-8 | 98246-87-8 | Long-term toxicity to fish | 22/09/2022 | 07/11/2022 | Details | |
3-ethyloxetane-3-methanol | 221-254-0 | 3047-32-3 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
3-methoxy-3-methylbutan-1-ol | 260-252-4 | 56539-66-3 | Long-term toxicity to fish | 26/10/2022 | 12/12/2022 | Details | |
3-methylpentane-1,5-diol | 224-709-1 | 4457-71-0 | Long-term toxicity to fish | 01/03/2023 | 17/04/2023 | Details | |
4,4'-isopropylidenedicyclohexanol | 201-244-2 | 80-04-6 | Long-term toxicity to fish | 17/06/2014 | 01/08/2014 | Details | |
4,4'-sulphonyldiphenol | 201-250-5 | 80-09-1 | Long-term toxicity to fish | 16/06/2022 | 01/08/2022 | Details | |
4,8-Dimethyl-2,5,7,10-tetraoxaundecane | 813-999-0 | 59039-15-5 | Long-term toxicity to fish | 30/06/2023 | 14/08/2023 | Details | |
4-methylpentan-2-one | 203-550-1 | 108-10-1 | Long-term toxicity to fish | 06/06/2023 | 21/07/2023 | Details | |
5,5'-dithiodi-1,3,4-thiadiazole-2(3H)-thione | 276-763-0 | 72676-55-2 | Long-term toxicity to fish | 30/06/2023 | 14/08/2023 | Details | |
6-tert-butyl-2,4-xylenol | 217-533-1 | 1879-09-0 | Long-term toxicity to fish | 15/07/2014 | 29/08/2014 | Details | |
[3aR-(3aα,5aβ,9aα,9bβ)]-dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan | 229-861-2 | 6790-58-5 | Long-term toxicity to fish | 22/09/2022 | 07/11/2022 | Details | |
Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide | 271-794-6 | 68608-66-2 | Long-term toxicity to fish | 18/02/2014 | 04/04/2014 | Details | |
Androst-4-ene-3,17-dione | 200-554-5 | 63-05-8 | Long-term toxicity to fish | 21/01/2021 | 08/03/2021 | Details | |
Aziridine | 205-793-9 | 151-56-4 | Long-term toxicity to fish | 26/01/2011 | 14/03/2011 | Details | |
Barium carbonate | 208-167-3 | 513-77-9 | Long-term toxicity to fish | 29/04/2011 | 14/06/2011 | Details | |
Barium hydroxide | 241-234-5 | 17194-00-2 | Long-term toxicity to fish | 29/04/2011 | 14/06/2011 | Details | |
Barium sulfate | 231-784-4 | 7727-43-7 | Long-term toxicity to fish | 29/04/2011 | 14/06/2011 | Details | |
benzenesulfonic acid, 4-c10-13-alkyl derivs.-, salts with amines, c16-c18 (even numbered) alkyl | 953-378-2 | - | Long-term toxicity to fish | 30/09/2021 | 15/11/2021 | Details | |
benzenesulfonic acid, mono- and dialkylation products with c16-20 (even numbered, branched and linear) olefins, calcium salts, calcium carbonate, overbased, including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic c15-c50 | 701-356-6 | - | Long-term toxicity to fish | 22/04/2021 | 07/06/2021 | Details | |
Benzyldimethylamine | 203-149-1 | 103-83-3 | Long-term toxicity to fish | 06/06/2023 | 21/07/2023 | Details | |
Bis(dibutyldithiocarbamato-S,S')copper | 237-695-7 | 13927-71-4 | Long-term toxicity to fish | 22/06/2017 | 07/08/2017 | Details | |
Bisdecanoyl peroxide | 212-092-1 | 762-12-9 | Long-term toxicity to fish | 27/09/2017 | 13/11/2017 | Details | |
Carboxymethyldimethyl-3-[[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulphonyl]amino]propylammonium hydroxide | 252-046-8 | 34455-29-3 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
Di-tert-butyl trisulphide | 224-226-6 | 4253-90-1 | Long-term toxicity to fish | 30/06/2023 | 14/08/2023 | Details | |
Dibutyl fumarate | 203-327-9 | 105-75-9 | Long-term toxicity to fish | 16/05/2011 | 30/06/2011 | Details | |
Dibutyl hydrogen phosphate | 203-509-8 | 107-66-4 | Long-term toxicity to fish | 10/05/2022 | 27/06/2022 | Details | |
Diethylmethylbenzenediamine | 270-877-4 | 68479-98-1 | Long-term toxicity to fish | 04/12/2023 | 18/01/2024 | Details | |
Dodecanoic acid, 2,2-dimethyl-3-oxopropyl ester | 468-880-2 | 102985-93-3 | Long-term toxicity to fish | 30/09/2021 | 15/11/2021 | Details | |
Esterification products of fatty acids, C18 (unsaturated) alkyl and adipic acid with pentaerythritol | 952-795-7 | - | Long-term toxicity to fish | 03/11/2023 | 18/12/2023 | Details | |
Fatty acids, C16-18 and C18-unsatd., Et esters | 285-206-0 | 85049-36-1 | Long-term toxicity to fish | 01/07/2011 | 15/08/2011 | Details | |
Fatty acids, C18-unsatd., reaction products with diethylenetriamine | 629-715-1 | 1226892-43-8 | Long-term toxicity to fish | 26/10/2022 | 12/12/2022 | Details | |
Fatty acids, tall-oil, compds. with N-[3-(dimethylamino)propyl]tall-oil amides | 295-714-4 | 92128-22-8 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
Fatty acids, tall-oil, compds. with oleylamine | 288-315-1 | 85711-55-3 | Long-term toxicity to fish | 04/04/2014 | 19/05/2014 | Details | |
Fatty acids, tall-oil, reaction products with acrylic acid | 939-424-4 | - | Long-term toxicity to fish | 04/04/2014 | 19/05/2014 | Details | |
Heptanoic acid | 203-838-7 | 111-14-8 | Long-term toxicity to fish | 31/01/2023 | 17/03/2023 | Details | |
Hexyl 2-(1-(diethylaminohydroxyphenyl)methanoyl)benzoate | 443-860-6 | 302776-68-7 | Long-term toxicity to fish | 16/08/2011 | 30/09/2011 | Details | |
Imidazolidine-2-thione | 202-506-9 | 96-45-7 | Long-term toxicity to fish | 29/04/2011 | 14/06/2011 | Details | |
Isononanoic acid, C16-18 (even numbered)-alkyl esters | 601-141-6 | 111937-03-2 | Long-term toxicity to fish | 01/04/2022 | 16/05/2022 | Details | |
Mercaptoacetic acid | 200-677-4 | 68-11-1 | Long-term toxicity to fish | 31/01/2023 | 17/03/2023 | Details | |
methyl acrylate; methyl propenoate | 202-500-6 | 96-33-3 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
Multi-Wall Carbon Nanotubes, synthetic graphite in tubular shape | 231-955-3 | 7782-42-5 | Long-term toxicity to fish | 03/11/2011 | 19/12/2011 | Details | |
N,N-dimethyldecan-1-amide | 238-405-1 | 14433-76-2 | Long-term toxicity to fish | 15/07/2011 | 29/08/2011 | Details | |
N-(2-nitrophenyl)phosphoric triamide | 477-690-9 | - | Long-term toxicity to fish | 18/03/2021 | 03/05/2021 | Details | |
N-butyl phenyl ether | 214-426-1 | 1126-79-0 | Long-term toxicity to fish | 03/04/2023 | 22/05/2023 | Details | |
Naphthenic acids | 215-662-8 | 1338-24-5 | Long-term toxicity to fish | 01/07/2011 | 15/08/2011 | Details | |
Oxydipropyl dibenzoate | 248-258-5 | 27138-31-4 | Long-term toxicity to fish | 10/08/2018 | 24/09/2018 | Details | |
p-cresol | 203-398-6 | 106-44-5 | Long-term toxicity to fish | 10/05/2022 | 27/06/2022 | Details | |
Pentaerythritol | 204-104-9 | 115-77-5 | Long-term toxicity to fish | 03/05/2023 | 19/06/2023 | Details | |
Pentaerythritol tetrakis(3-mercaptopropionate) | 231-472-8 | 7575-23-7 | Long-term toxicity to fish | 01/07/2021 | 16/08/2021 | Details | |
Polyamide wax | 434-430-9 | - | Long-term toxicity to fish | 07/07/2020 | 21/08/2020 | Details | |
potassium titanium oxide (K2Ti6O13) | 432-240-0 | 12056-51-8 | Long-term toxicity to fish | 17/05/2017 | 03/07/2017 | Details | |
Prop-2-yn-1-ol | 203-471-2 | 107-19-7 | Long-term toxicity to fish | 22/09/2022 | 07/11/2022 | Details | |
Reaction mass of 1,3-dioxane-5,5-dimethanol and 1,3-Propanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]- | 911-819-6 | - | Long-term toxicity to fish | 31/01/2023 | 17/03/2023 | Details | |
Reaction mass of 2-ethyl-2-(methoxymethyl)-propane-1,3-diol and 2-ethylpropane-1,3-diol | 938-572-7 | - | Long-term toxicity to fish | 22/09/2022 | 07/11/2022 | Details | |
Reaction mass of ethoxylated (= 3 moles) bisphenol A dimethacrylate and (1-methylethylidene)bis(4,1-phenyleneoxy-2,1-ethanediyl) bismethacrylate | 939-702-5 | - | Long-term toxicity to fish | 25/11/2019 | 09/01/2020 | Details | |
reaction products of 1,4-butanediol with 1,3-chloro-2,3-epoxypropane, esters with prop-2-enoic acid | 701-230-0 | - | Long-term toxicity to fish | 10/05/2022 | 27/06/2022 | Details | |
Reaction products of n-octanol and acrylic acid, first distillation pitch | 938-925-5 | - | Long-term toxicity to fish | 15/01/2024 | 29/02/2024 | Details | |
Reaction products of tetrazotized 5-amino-2-[(E)-2-(4-amino-2-sulfophenyl)ethenyl]benzenesulfonic acid with 6-amino-4-hydroxynaphthalene-2-sulfonic acid and 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid in 2-[bis(2-hydroxyethyl)amino]ethanol | 916-899-6 | - | Long-term toxicity to fish | 25/11/2021 | 10/01/2022 | Details | |
Silsesquioxanes, phenyl | - | 70131-69-0 | Long-term toxicity to fish | 18/09/2014 | 03/11/2014 | Details | |
Strontium carbonate | 216-643-7 | 1633-05-2 | Long-term toxicity to fish | 31/05/2011 | 15/07/2011 | Details | |
Strontium chromate | 232-142-6 | 7789-06-2 | Long-term toxicity to fish | 31/05/2011 | 15/07/2011 | Details | |
Styrene | 202-851-5 | 100-42-5 | Long-term toxicity to fish | 30/06/2023 | 14/08/2023 | Details | |
Styrene | 202-851-5 | 100-42-5 | Long-term toxicity to fish | 04/09/2023 | 19/10/2023 | Details | |
SUMILIZER GP | 442-450-4 | - | Long-term toxicity to fish | 25/11/2021 | 10/01/2022 | Details | |
tert-butyl perbenzoate | 210-382-2 | 614-45-9 | Long-term toxicity to fish | 23/03/2020 | 07/05/2020 | Details | |
tert-dodecanethiol | 246-619-1 | 25103-58-6 | Long-term toxicity to fish | 16/06/2022 | 01/08/2022 | Details | |
Tetramethylammonium hydroxide | 200-882-9 | 75-59-2 | Long-term toxicity to fish | 30/06/2023 | 14/08/2023 | Details | |
Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarboxylate | 266-442-3 | 66669-53-2 | Long-term toxicity to fish | 22/09/2022 | 07/11/2022 | Details | |
trimethoxy(2,4,4-trimethylpentyl)silane | 251-995-5 | 34396-03-7 | Long-term toxicity to fish | 26/10/2022 | 12/12/2022 | Details | |
Trimethylolpropane and its reaction products with methyloxirane | 957-630-2 | - | Long-term toxicity to fish | 15/01/2024 | 29/02/2024 | Details | |
Triphenylphosphine | 210-036-0 | 603-35-0 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
undec-10-enoic acid | 203-965-8 | 112-38-9 | Long-term toxicity to fish | 16/10/2014 | 01/12/2014 | Details | |
Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl | 905-837-3 | - | Long-term toxicity to fish || Note: substance forms part of category; testing is also proposed with Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI), Octylamine and Hexamethylenediamine (EC no. 923-615-4) | 26/08/2021 | 11/10/2021 | Details | |
Reaction products of C18 (unsaturated) fatty acids and dimethyl sulfate and triethanolamine | 931-216-1 | - | Long-term toxicity to fish || Note: testing proposed with Fatty acids, C16-18 (even numbered) and C18 unsatd., reaction products with diethylene triamine, di-Me sulfate quaternized (EC 937-237-2) | 22/04/2021 | 07/06/2021 | Details | |
Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (101-68-8), Octylamine (111-86-4) and Cyclohexylamine (108-91-8) | 926-119-6 | - | Long-term toxicity to fish || Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (CAS: 101-68-8), Octylamine (111-86-4) and Hexamethylenediamine (124-09-4) (EC no 924-670-7) | 30/09/2021 | 15/11/2021 | Details | |
1-Dodecanamine, reaction products with 1,1'-methylenebis[4-isocyanatobenzene] and 1-octanamine | 812-490-0 | 1312943-21-7 | Long-term toxicity to fish || Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (Octylamine and Hexamethylenediamine (EC no. 924-670-7) | 26/08/2021 | 11/10/2021 | Details | |
1-Octadecanamine, reaction products with 1,1'-methylenebis[4-isocyanatobenzene] and 1-octanamine | 812-491-6 | 1312943-23-9 | Long-term toxicity to fish || Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) , Octylamine) and Hexamethylenediamine (EC no. 924-670-7) | 26/08/2021 | 11/10/2021 | Details | |
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11-C13 odd-numbered alkyl) derivs. and sodium hydroxide and chloroacetic acid | 938-645-3 | - |
Long-term toxicity to fish
Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C11 alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 271-794-6) Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0) Sub-chronic toxicity (90-day): oral
Note: testing proposed with [Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid] (EC 931-291-0) |
16/03/2015 16/03/2015 16/03/2015 |
30/04/2015 30/04/2015 30/04/2015 |
Details | |
Reaction mass of 2,4,6,8,10-pentamethyl-2,4,6,8,10-pentavinylcyclopentasiloxane and 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane | 911-381-6 | - | Long-term toxicity to fish || Note: testing proposed with 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane (EC 219-863-1) || Note: Testing proposal is based on concern identified by the registrant | 17/06/2020 | 03/08/2020 | Details | |
Triethoxyoctylsilane | 220-941-2 | 2943-75-1 | Long-term toxicity to fish || Note: testing proposed with Triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1) | 17/04/2015 | 04/06/2015 | Details | |
2-methylpropan-1-ol | 201-148-0 | 78-83-1 | Long-term toxicity to fish ||Note: testing proposed with Propan-1-ol (EC no. 200-746-9) ||Note: testing proposed with Pentan-1-ol (EC no. 200-752-1) | 26/10/2022 | 12/12/2022 | Details | |
Strontium hydroxide | 242-367-1 | 18480-07-4 |
Long-term toxicity to fish
Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9) Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9) Reproductive toxicity (two-generation reproductive toxicity)
Note: testing proposed with strontium dinitrate (EC: 233-131-9, CAS: 10042-76-9) |
15/04/2014 15/04/2014 15/04/2014 |
30/05/2014 30/05/2014 30/05/2014 |
Details | |
Benzyltoluene | 248-654-8 | 27776-01-8 | Long-term toxicity to fish (OECD 210) | 25/06/2019 | 09/08/2019 | Details | |
Fatty acids, C12-14, α-sulfo, disodium salts | 942-523-5 | - |
Long-term toxicity to fish (OECD 212 – Registrant’s preference) Reproductive toxicity (pre-natal developmental toxicity) on rodents Sub-chronic toxicity (90-day): oral on rodents |
25/06/2019 25/06/2019 25/06/2019 |
09/08/2019 09/08/2019 09/08/2019 |
Details | |
Fatty acids, C16-18, barium salts | 292-883-6 | 91002-07-2 | Long-term toxicity to fish //Note: testing to be done with barium dichloride (CAS number 10361-37-2) | 04/04/2014 | 19/05/2014 | Details | |
2,4,7,9-tetramethyl-4,7-decanediol | 451-160-7 | 17913-76-7 |
Long-term toxicity to fish "|| Note: testing proposed with 2,4,7,9-tetramethyldec-5-yne-4,7-diol (EC 204-809-1, CAS 126-86-3) Reproductive toxicity (pre-natal developmental toxicity) |
17/09/2019 17/09/2019 |
01/11/2019 01/11/2019 |
Details | |
Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide | 271-794-6 | 68608-66-2 | Long-term toxicity to fish Sub-chronic toxicity (90-day): oral || Note: testing proposed with Reaction products of 1H-Imidazole- 1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0) Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0 | 29/02/2016 | 14/04/2016 | Details | |
benzyl butyl cis-cyclohexane-1,2-dicarboxylate | 701-279-8 | 1931129-39-3 |
Long-term toxicity to fish || Note: Link to the registration dossier not given as the dossier not yet disseminated. || Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5 Reproductive toxicity (pre-natal developmental toxicity) || Note: Link to registration dossier not given as the dossier not yet disseminated. || Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5 Sub-chronic toxicity (90-day): oral || Note: Link to registration dossier not given as the dossier not yet disseminated. || Note: this substance was previously registered, identified and disseminated with EC No. 810-685-5 |
10/12/2018 10/12/2018 10/12/2018 |
24/01/2019 24/01/2019 24/01/2019 |
Details | |
1,1,4,4-tetramethylbutane-1,4-diyl bis(2-ethylperoxyhexanoate) | 235-935-5 | 13052-09-0 | Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates | 12/12/2014 | 26/01/2015 | Details | |
2-ethyl-2-[[(1-oxononyl)oxy]methyl]propane-1,3-diyl dinonan-1-oate | 204-793-6 | 126-57-8 | Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates | 17/04/2015 | 04/06/2015 | Details | |
bis(piperidinothiocarbonyl) hexasulphide | 213-537-2 | 971-15-3 | Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates | 16/02/2015 | 02/04/2015 | Details | |
tert-butyl α,α-dimethylbenzyl peroxide | 222-389-8 | 3457-61-2 | Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates | 16/03/2015 | 30/04/2015 | Details | |
N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan-1-amide) | 204-613-6 | 123-26-2 |
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with: “Octadecanoic acid, 12-hydroxy-, reaction products with ethylenediamine”, CAS 100545-48-0 Sub-chronic toxicity (90 day): oral |
30/09/2015 30/09/2015 30/09/2015 |
16/11/2015 16/11/2015 16/11/2015 |
Details | |
Fats and Glyceridic oils, vegetable, winterized, reaction products with ammonia-ethanolamine reaction products | 800-253-4 | - |
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates. Link to registration dossier not given as the dossier not yet disseminated. |
30/11/2015 | 14/01/2016 | Details | |
Triethoxy(2,4,4-trimethylpentyl)silane | 252-558-1 | 35435-21-3 |
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates. Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1) |
28/02/2018 28/02/2018 |
16/04/2018 16/04/2018 |
Details | |
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-C12-14 acyl derivs., hydroxides, inner salts | 293-878-1 | 91648-19-0 |
Long-term toxicity to fish || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-457-4) Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3) Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts (EC 939-455-3) |
18/06/2018 18/06/2018 18/06/2018 |
02/08/2018 02/08/2018 02/08/2018 |
Details | |
Reaction product of 4,4'-methylenediphenyl diisocyanate, Octylamine and Hexamethylenediamine | 924-670-7 | - | Long-term toxicity to fish || Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC no. 905-837-3) | 16/06/2022 | 01/08/2022 | Details | |
2-Oxetanone, 3-C12-16-alkyl-4-C13-17-alkylidene derivs., (4E)- | 939-401-9 | 1469983-41-2 | Long-term toxicity to fish ||Note: testing proposed with 2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs (EC no. 308-760-8) | 15/07/2022 | 29/08/2022 | Details | |
Heptan-1-ol | 203-897-9 | 111-70-6 |
Long-term toxicity to fish Long-term toxicity to fish Sub-chronic toxicity (90 day): Oral |
04/09/2012 18/02/2014 04/09/2012 |
19/10/2012 04/04/2014 19/10/2012 |
Details | |
Alcohols, C13-15-branched and linear | 287-625-4 | 85566-16-1 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) |
31/01/2023 31/01/2023 |
17/03/2023 17/03/2023 |
Details | |
Bis(2-ethylhexyl) adipate | 203-090-1 | 103-23-1 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) |
01/04/2022 01/04/2022 |
16/05/2022 16/05/2022 |
Details | |
N,N-dimethyl-alkyl-1-amines, reaction products with alkali hydroxide and chloroacetic acid | 939-682-8 | - |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) |
10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 |
Details | |
Octadecanoic acid, 12-hydroxy-, reaction products with decanoic acid and ethylenediamine | 907-495-0 | - |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) |
01/04/2022 01/04/2022 |
16/05/2022 16/05/2022 |
Details | |
N-octadecylstearamide | 236-276-6 | 13276-08-9 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) |
17/04/2015 17/04/2015 17/04/2015 |
04/06/2015 04/06/2015 04/06/2015 |
Details | |
Phosphoric acid, octadecyl ester | 254-466-7 | 39471-52-8 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/04/2015 17/04/2015 17/04/2015 17/04/2015 |
04/06/2015 04/06/2015 04/06/2015 04/06/2015 |
Details | |
5-ethyl-1,3-dioxane-5-methanol | 225-967-8 | 5187-23-5 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
03/10/2023 03/10/2023 03/10/2023 |
17/11/2023 17/11/2023 17/11/2023 |
Details | |
Alcohols, C8-10, ethoxylated | 615-247-5 | 71060-57-6 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
22/09/2022 22/09/2022 22/09/2022 |
07/11/2022 07/11/2022 07/11/2022 |
Details | |
Fatty acids, C8-10, C12-18-alkyl esters | 306-082-7 | 95912-86-0 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
01/04/2022 01/04/2022 01/04/2022 |
16/05/2022 16/05/2022 16/05/2022 |
Details | |
Octyl octanoate | 218-980-5 | 2306-88-9 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
03/04/2023 03/04/2023 03/04/2023 |
22/05/2023 22/05/2023 22/05/2023 |
Details | |
Reaction mass of 2-(1,1-dimethylpropyl)anthraquinone and 2-(1,2-dimethylpropyl)anthraquinonedimethylpropyl)anthraquinone | 915-623-1 | - |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
27/09/2017 27/09/2017 27/09/2017 |
13/11/2017 13/11/2017 13/11/2017 |
Details | |
12-hydroxystearic acid | 203-366-1 | 106-14-9 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/10/2023 03/10/2023 03/10/2023 03/10/2023 |
17/11/2023 17/11/2023 17/11/2023 17/11/2023 |
Details | |
1,2-dihydroxybenzene,pyrocatechol | 204-427-5 | 120-80-9 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) |
15/04/2011 15/04/2011 |
30/05/2011 30/05/2011 |
Details | |
6-tert-butyl-2,4-xylenol | 217-533-1 | 1879-09-0 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) |
18/02/2021 18/02/2021 |
05/04/2021 05/04/2021 |
Details | |
Ethanol, 2,2'-iminobis-, N-(C13-15-branched and linear alkyl) derivs. | 308-208-6 | 97925-95-6 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) |
29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 |
Details | |
N,N’-di[3-(p-toluene sulfonyl)oxy]phenyl urea | 876-151-9 | 2292123-68-1 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) |
03/04/2023 03/04/2023 |
22/05/2023 22/05/2023 |
Details | |
Oleic acid, compound with (Z)-N-octadec-9-enylpropane-1,3-diamine (2:1) | 251-846-4 | 34140-91-5 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) |
10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 |
Details | |
tert-butyl perbenzoate | 210-382-2 | 614-45-9 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) |
16/06/2011 16/06/2011 |
01/08/2011 01/08/2011 |
Details | |
Thymol | 201-944-8 | 89-83-8 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) |
16/06/2022 16/06/2022 |
01/08/2022 01/08/2022 |
Details | |
2,4,8,10-tetra(tert-butyl)-6-hydroxy-12H-dibenzo[d,g][1,3,2]dioxaphosphocin 6-oxide, sodium salt | 286-344-4 | 85209-91-2 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
16/10/2014 16/10/2014 16/10/2014 |
01/12/2014 01/12/2014 01/12/2014 |
Details | |
4-tert-butylpyrocatechol | 202-653-9 | 98-29-3 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
29/04/2011 29/04/2011 29/04/2011 |
14/06/2011 14/06/2011 14/06/2011 |
Details | |
Barium chloride | 233-788-1 | 10361-37-2 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
29/04/2011 29/04/2011 29/04/2011 |
14/06/2011 14/06/2011 14/06/2011 |
Details | |
Strontium nitrate | 233-131-9 | 10042-76-9 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
31/05/2011 31/05/2011 31/05/2011 |
15/07/2011 15/07/2011 15/07/2011 |
Details | |
Sulphamidic acid | 226-218-8 | 5329-14-6 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
14/02/2011 14/02/2011 14/02/2011 |
31/03/2011 31/03/2011 31/03/2011 |
Details | |
Quaternary ammonium compounds, bis(hydrogenated tallow alkyl)dimethyl, chlorides, reaction products with polyethylenepolyamines and tall-oil fatty acids, humates hydrochlorides | 272-745-1 | 68910-55-4 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): inhalation |
23/01/2015 23/01/2015 23/01/2015 23/01/2015 |
09/03/2015 09/03/2015 09/03/2015 09/03/2015 |
Details | |
2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine | 426-040-2 | 25713-60-4 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/06/2011 16/06/2011 16/06/2011 16/06/2011 |
01/08/2011 01/08/2011 01/08/2011 01/08/2011 |
Details | |
2-Butenedioic acid (Z)-, ester with 1,2-propanediol, compd. with 2-(dibutylamino)ethanol | 286-304-6 | 85204-10-0 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/06/2014 02/06/2014 02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 17/07/2014 17/07/2014 |
Details | |
Fatty acids, tall-oil, reaction products with triethanolamine | 267-053-1 | 67784-78-5 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
29/07/2011 29/07/2011 29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 12/09/2011 12/09/2011 |
Details | |
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C8-18(even numbered) acyl) derivs., hydroxides, inner salts | 939-455-3 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): oral |
18/09/2014 18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 03/11/2014 |
Details | |
(octahydro-4,7-methano-1H-indenediyl)bis(methylene) diacrylate | 255-901-3 | 42594-17-2 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
22/04/2021 22/04/2021 22/04/2021 |
07/06/2021 07/06/2021 07/06/2021 |
Details | |
1,3,5-tris(2,3-dibromopropyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione | 257-913-4 | 52434-90-9 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/04/2023 03/04/2023 03/04/2023 |
22/05/2023 22/05/2023 22/05/2023 |
Details | |
1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)carbamate | 411-700-4 | 140921-24-0 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
10/05/2022 10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 27/06/2022 |
Details | |
1-Propanaminium, N-(3-aminopropyl)-2-hydroxy-N,N-dimethyl-3-sulfo-, N-(C12-18(even numbered) acyl) derivs., hydroxides, inner salts | 939-457-4 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/09/2014 18/09/2014 18/09/2014 |
03/11/2014 03/11/2014 03/11/2014 |
Details | |
3-hydroxy-1,1-dimethylbutyl 2-ethyl-2-methylheptaneperoxoate | 413-910-1 | 95718-78-8 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/04/2012 17/04/2012 17/04/2012 |
01/06/2012 01/06/2012 01/06/2012 |
Details | |
4,4'-oxydi(benzenesulphonohydrazide) | 201-286-1 | 80-51-3 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
21/03/2014 21/03/2014 21/03/2014 |
05/05/2014 05/05/2014 05/05/2014 |
Details | |
4,4`-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with methacrylic acid | 500-089-0 | 36425-15-7 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
01/07/2011 01/07/2011 01/07/2011 |
15/08/2011 15/08/2011 15/08/2011 |
Details | |
A dried sludge product resulting from the treatment process of domestic wastewater. The exact processes followed for the production of the dried sludge are: Preliminary and secondary treatment of the wastewater stream, thickening, dehydration and drying of the excess sludge. | 943-834-9 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/04/2023 03/04/2023 03/04/2023 |
22/05/2023 22/05/2023 22/05/2023 |
Details | |
A mixture of cis- and trans-cyclohexadec-8-en-1-one | 401-700-2 | 3100-36-5 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
28/11/2022 28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 12/01/2023 |
Details | |
Condensation products of triethanolamine with addition products of fatty acids, C18 (unsaturated) alkyl with maleic anhydride | - | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
10/03/2017 10/03/2017 10/03/2017 |
25/04/2017 25/04/2017 25/04/2017 |
Details | |
Di-tert-butyl peroxide | 203-733-6 | 110-05-4 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
01/07/2011 01/07/2011 01/07/2011 |
15/08/2011 15/08/2011 15/08/2011 |
Details | |
Diphosphoric acid, compd. with piperazine (1:1) | 457-330-7 | 66034-17-1 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
10/05/2022 10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 27/06/2022 |
Details | |
Fatty acids, C12-18 (even numbered)-methyl esters, sulfonated, sodium salts | 947-394-9 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
19/10/2020 19/10/2020 19/10/2020 |
03/12/2020 03/12/2020 03/12/2020 |
Details | |
Fatty acids, C14-18 and C16-18-unsatd., maleated | - | 85711-46-2 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
11/11/2016 11/11/2016 11/11/2016 |
03/01/2017 03/01/2017 03/01/2017 |
Details | |
Fatty acids, C16-18, isononyl esters | 292-960-4 | 91031-57-1 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/06/2023 30/06/2023 30/06/2023 |
14/08/2023 14/08/2023 14/08/2023 |
Details | |
Hexanoic acid, 3,5,5-trimethyl-, 2,2,6,6-tetramethyl-1-[2-[(3,5,5-trimethyl-1-oxohexyl)oxy]ethyl]-4-piperidinyl ester | 941-267-1 | 1445870-18-7 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/01/2023 31/01/2023 31/01/2023 |
17/03/2023 17/03/2023 17/03/2023 |
Details | |
N-(2-hydroxypropyl)oleamide | 203-828-2 | 111-05-7 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/08/2014 14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 28/09/2014 |
Details | |
N1,N3‐bis(3‐methylphenyl)‐5‐[(3‐methylphenyl)sulfamoyl]benzene‐1,3‐dicarboxamide | 951-483-8 | 2375645-78-4 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/06/2022 16/06/2022 16/06/2022 |
01/08/2022 01/08/2022 01/08/2022 |
Details | |
O-(2-ethylhexyl) O,O-tert-pentyl peroxycarbonate | 274-919-2 | 70833-40-8 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/10/2023 03/10/2023 03/10/2023 |
17/11/2023 17/11/2023 17/11/2023 |
Details | |
Octanethioic acid, S-[3-(triethoxysilyl)propyl] ester, reaction products with 2-methyl-1,3-propanediol and 3-(triethoxysilyl)-1-propanethiol | 485-270-1 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
28/11/2022 28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 12/01/2023 |
Details | |
Reaction mass of [[(2-hydroxyethyl)imino]bis(methylene)]bisphosphonic acid and Phosphonic acid, P-[(tetrahydro-2-hydroxy-2-oxido-4H-1,4,2-oxazaphosphorin-4-yl)methyl]- | 911-811-2 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/04/2015 17/04/2015 17/04/2015 |
04/06/2015 04/06/2015 04/06/2015 |
Details | |
Sodium hydroxymethanesulphinate | 205-739-4 | 149-44-0 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/04/2011 15/04/2011 15/04/2011 |
30/05/2011 30/05/2011 30/05/2011 |
Details | |
Tetrakis(phenylmethyl)thioperoxydi(carbothioamide) | 404-310-0 | 10591-85-2 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/09/2021 30/09/2021 30/09/2021 |
15/11/2021 15/11/2021 15/11/2021 |
Details | |
Aluminum triformate | 230-898-1 | 7360-53-4 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity study (90-day): oral |
21/01/2011 21/01/2011 21/01/2011 |
07/03/2011 07/03/2011 07/03/2011 |
Details | |
1,10-decanediyl diacrylate | 235-922-4 | 13048-34-5 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Esterification products of acrylic acid with reaction products of 2,2-dimethylpropane-1,3-diol and methyloxirane (EC no. 701-440-2) Sub-chronic toxicity (90-day): oral||Note: testing proposed with Esterification products of acrylic acid with reaction products of 2,2-dimethylpropane-1,3-diol and methyloxirane (EC no. 701-440-2) |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
Pentane-2,4-dione | 204-634-0 | 123-54-6 |
Long-term toxicity to fish Reproductive toxicity (two-generation reproductive toxicity) |
15/07/2011 15/07/2011 |
29/08/2011 29/08/2011 |
Details | |
di(morpholin-4-yl) disulphide | 203-103-0 | 103-34-4 |
Long-term toxicity to fish Sub-chronic toxicity (90-day): oral |
29/04/2011 29/04/2011 |
14/06/2011 14/06/2011 |
Details | |
Ethyl 4-dimethylaminobenzoate | 233-634-3 | 10287-53-3 |
Long-term toxicity to fish Sub-chronic toxicity (90-day): oral |
10/05/2022 10/05/2022 |
27/06/2022 27/06/2022 |
Details | |
Isodecyl methacrylate | 249-978-2 | 29964-84-9 |
Long-term toxicity to fish Sub-chronic toxicity (90-day): oral |
03/10/2023 03/10/2023 |
17/11/2023 17/11/2023 |
Details | |
Reaction mass of Amides, rape-oil, N-(hydroxyethyl), ethoxylated and Glycerol, ethoxylated | 932-164-2 | - |
Long-term toxicity to fish Sub-chronic toxicity (90-day): oral |
29/07/2011 29/07/2011 |
12/09/2011 12/09/2011 |
Details | |
N,N'-(methylenedi-p-phenylene)bis[hexahydro-2-oxo-1H-azepine-1-carboxamide] | 258-981-8 | 54112-23-1 |
Long-term toxicity to fish Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates. |
31/08/2015 | 15/10/2015 | Details | |
m-cresol | 203-577-9 | 108-39-4 | Long-term toxicity to fish|| Note: testing proposed with p-cresol (EC no. 203-398-6) | 10/05/2022 | 27/06/2022 | Details | |
Diisononyl adipate | 251-646-7 | 33703-08-1 |
Long-term toxicity to fish||Note: Read across testing proposed with Bis(2-ethylhexyl) adipate (EC no. 203-090-1) Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: Read across testing proposed with Bis(2-ethylhexyl) adipate (EC no. 203-090-1) |
03/05/2023 03/05/2023 |
19/06/2023 19/06/2023 |
Details | |
3-trimethoxysilylpropane-1-thiol | 224-588-5 | 4420-74-0 | Long-term toxicity to fish||Note: testing proposed with 3-Triethoxysilylpropane-1-thiol (EC no. 238-883-1) | 22/09/2022 | 07/11/2022 | Details | |
Benzenesulfonic acid, mono- and dialkylation products with C16-20 (even numbered, branched and linear) olefins, magnesium salts, magnesium carbonate, overbased, including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic C15-C50 | 701-469-0 | - | Long-term toxicity to fish||Note: testing proposed with Benzenesulfonic acid, mono- and dialkylation products with C16-20 (even numbered, branched and linear) olefins, calcium salts, calcium carbonate, overbased, including distillates (petroleum), hydrotreated, solvent-refined, solvent-dewaxed, or catalytic dewaxed, light or heavy paraffinic C15-C50 (EC no. 701-356-6) | 04/09/2023 | 19/10/2023 | Details | |
C18 unsaturated fatty acids, reaction products with 1-aminopropan-2-ol, maleic anhydride and sodium bisulfite | 947-655-7 | - | Long-term toxicity to fish||Note: testing proposed with disodium 4-[1-methyl-2-[(1-oxooctadec-9-enyl)amino]ethyl] 2-sulphonatosuccinate (EC no. 267-199-6) | 15/01/2024 | 29/02/2024 | Details | |
A mixture of: triphenylthiophosphate and tertiary butylated phenyl derivatives | 421-820-9 | 192268-65-8 | Long-term toxicity to fish||Note: testing proposed with O,O,O-triphenyl phosphorothioate (EC no. 209-909-9) | 04/12/2023 | 18/01/2024 | Details | |
o-cresol | 202-423-8 | 95-48-7 | Long-term toxicity to fish||Note: testing proposed with p-cresol (EC no. 203-398-6) | 10/05/2022 | 27/06/2022 | Details | |
3-methylbutan-1-ol | 204-633-5 | 123-51-3 | Long-term toxicity to fish||Note: testing proposed with Pentan-1-ol (EC no. 200-752-1) | 22/09/2022 | 07/11/2022 | Details | |
2-phosphonobutane-1,2,4-tricarboxylic acid | 253-733-5 | 37971-36-1 |
Long-term toxicity to fish||Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3) |
26/10/2022 26/10/2022 |
12/12/2022 12/12/2022 |
Details | |
Cyclohexane-1,4-diyldimethanol | 203-268-9 | 105-08-8 | OECD Guideline 414 (Prenatal Developmental Toxicity Study) | 19/11/2010 | 03/01/2011 | Details | |
Reaction mass of resin acids and rosin acids, hydrogenated, potassium salts and potassium [1R-(1a,4aß,10aa)]-1,2,3,4,4a,9,10,10a-octahydro-7-isopropyl-1,4a-dimethylphenanthren-1-carboxylate | 915-657-7 | - |
Pre-natal developmental toxicity, //Note:
Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8) Two-generation reproductive toxicity, //Note:
Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8) |
19/07/2013 19/07/2013 |
02/09/2013 02/09/2013 |
Details | |
Reaction mass of resin acids and rosin acids, hydrogenated, sodium salts and sodium [1R-(1a,4aß,10aa)]-1,2,3,4,4a,9,10,10a-octahydro-7- -isopropyl-1,4a-dimethylphenanthren-1-carboxylate | 915-568-3 | - |
Pre-natal developmental toxicity, //Note:
Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8) Two-generation reproductive toxicity, //Note:
Testing proposed with Rosin (CAS RN 8050-09-7) and Reaction mass of hydrogenated and dehydrogenated rosin (CAS RN 911-238-8) |
19/07/2013 19/07/2013 |
02/09/2013 02/08/2013 |
Details | |
Orthoboric acid, compound with 2-aminoethanol | 247-421-8 | 26038-87-9 | Repeated dose toxicity (90-day): oral | 17/11/2011 | 02/01/2012 | Details | |
12-hydroxyoctadecanoic acid, reaction products with 1,3-benzenedimethanamine and hexamethylenediamine | 432-840-2 | 220926-97-6 | Repeated dose toxicity: Inhalation | 04/05/2010 | 18/06/2010 | Details | |
4,4'-methylenebis[N,N-bis(2,3-epoxypropyl)aniline] | 249-204-3 | 28768-32-3 |
Reproduction toxicity (two generation reproductive toxicity) Reproductive toxicity (developmental toxicity) Sub-chronic toxicity (90-day): dermal |
26/01/2011 26/01/2011 26/01/2011 |
14/03/2011 14/03/2011 14/03/2011 |
Details | |
1,6-Bis((dibenzylthiocarbamoyl)disulfanyl)hexane | 429-280-6 | 151900-44-6 | Reproductive toxicity (developmental toxicity) | 01/09/2010 | 15/10/2010 | Details | |
11-aminoundecanoic acid | 219-417-6 | 2432-99-7 | Reproductive toxicity (developmental toxicity) | 08/04/2010 | 24/05/2010 | Details | |
2,2'-[oxybis(methylene)]-bis[2-ethylpropane-1,3-diol] | 245-509-0 | 23235-61-2 | Reproductive toxicity (developmental toxicity) | 26/01/2011 | 14/03/2011 | Details | |
3-amino-4-octanol | 482-070-6 | 1001354-72-8 | Reproductive toxicity (developmental toxicity) | 19/11/2010 | 03/01/2011 | Details | |
Sodium phosphinate | 231-669-9 | 7681-53-0 | Reproductive toxicity (developmental toxicity) | 26/01/2011 | 14/03/2011 | Details | |
Hydrogenated oligomerisation product, including dimers and trimers, of tetradec-1-ene and alkene | - | - |
Reproductive toxicity (developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
10/08/2009 10/08/2009 |
24/09/2009 24/09/2009 |
Details | |
2,3-epoxypropyl neodecanoate | 247-979-2 | 26761-45-5 |
Reproductive toxicity (developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day) |
26/05/2010 26/05/2010 26/05/2010 |
12/07/2010 12/07/2010 12/07/2010 |
Details | |
4-((Triethoxysilyl)methyl) morpholine | 480-370-1 | 21743-27-1 |
Reproductive toxicity (developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day) |
27/11/2009 27/11/2009 27/11/2009 |
11/01/2010 11/01/2010 11/01/2010 |
Details | |
3-Sulfanylpropanoic acid | 203-537-0 | 107-96-0 |
Reproductive toxicity (developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
05/04/2011 05/04/2011 05/04/2011 |
20/05/2011 20/05/2011 20/05/2011 |
Details | |
Mono- and/or di- and/or tri(1-phenylethyl)-m-cresol and p-cresol | 700-427-9 | - |
Reproductive toxicity (developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
01/12/2010 01/12/2010 01/12/2010 |
17/01/2011 17/01/2011 17/01/2011 |
Details | |
Dimethylpropane-1,3-diol | 204-781-0 | 126-30-7 |
Reproductive toxicity (developmental toxicity) Sub-chronic toxicity (90-day) |
26/01/2011 26/01/2011 |
14/03/2011 14/03/2011 |
Details | |
1,5-bis[1,2-bis(ethoxycarbonyl)ethylamino]-2-methylpentane | 433-260-2 | 168253-59-6 |
Reproductive toxicity (developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/09/2010 06/09/2010 |
20/10/2010 20/10/2010 |
Details | |
Reaction mass of 1,3-Propanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]- and 1,3-dioxane-5,5-dimethanol | 911-819-6 | - |
Reproductive toxicity (developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/02/2011 14/02/2011 |
31/03/2011 31/03/2011 |
Details | |
Tri-C18-22 (even numbered)-alkyl 2-hydroxypropane-1,2,3-tricarboxylate | 700-316-5 | - |
Reproductive toxicity (developmental toxicity) Sub-chronic toxicity (90-days): oral |
11/01/2011 11/01/2011 |
25/02/2011 25/02/2011 |
Details | |
Reaction mass of disodium hydroxysulfinatoacetate and disodium hydroxysulfonatoacetate | - | - |
Reproductive toxicity (developmental toxicity) Sub-chronic toxicity study (90-day): oral |
13/12/2010 13/12/2010 |
27/01/2011 27/01/2011 |
Details | |
Dodecamethylcyclohexasiloxane | 208-762-8 | 540-97-6 | Reproductive toxicity (extended one-generation reproductive toxicity study | 23/04/2018 | 07/06/2018 | Details | |