Previous Testing Proposals
Previous Testing Proposals
Previous Testing Proposals
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
Further instructions
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
There are currently no ongoing consultations.
| Resin acids and Rosin acids, maleated, calcium salts | 294-402-5 | 91722-01-9 |
Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0) Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0) |
02/07/2013 02/07/2013 |
16/08/2013 16/08/2013 |
Details | |
| Tar, wood | 294-436-0 | 91722-33-7 | Reproductive toxicity (pre-natal developmental toxicity) | 23/02/2022 | 12/04/2022 | Details | |
| Cobalt, borate 2-ethylhexanoate complexes | 295-032-7 | 91782-60-4 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4)
|| Note: Testing proposal is based on concern identified by the registrant Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant |
07/07/2020 07/07/2020 |
21/08/2020 21/08/2020 |
Details | |
| Cobalt, borate propionate complexes | 295-033-2 | 91782-61-5 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4)
|| Note: Testing proposal is based on concern identified by the registrant. Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant. |
21/09/2020 21/09/2020 |
05/11/2020 05/11/2020 |
Details | |
| Extracts (petroleum), deasphalted vacuum residue solvent | 295-332-8 | 91995-70-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): dermal |
28/02/2019 28/02/2019 28/02/2019 |
15/04/2019 15/04/2019 15/04/2019 |
Details | |
| Extracts (petroleum), deasphalted vacuum residue solvent | 295-332-8 | 91995-70-9 | Reproductive toxicity (two-generation reproductive toxicity) | 29/07/2011 | 12/09/2011 | Details | |
| Extracts (petroleum), deasphalted vacuum residue solvent | 295-332-8 | 91995-70-9 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Extracts (petroleum), residual oil solvent (EC no. 265-110-5) | 06/06/2023 | 21/07/2023 | Details | |
| Hydrocarbons, C4, steam-cracker distillate | 295-405-4 | 92045-23-3 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC no. 306-004-1) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC no. 306-004-1) Sub-chronic toxicity (90 day): inhalation||Note: testing proposed with Hydrocarbons, C4, 1,3-butadiene- and isobutene-free (EC no. 306-004-1) |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
| Gas oils (petroleum), hydrotreated light vacuum | 295-407-5 | 92045-24-4 | Reproductive toxicity (two-generation reproductive toxicity) | 15/07/2011 | 29/08/2011 | Details | |
| Residues (petroleum), thermal cracked vacuum | 295-518-9 | 062-05-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Asphalt (CAS 8052-42-4) | 25/06/2019 | 09/08/2019 | Details | |
| Residues (petroleum), thermal cracked vacuum | 295-518-9 | 92062-05-0 |
Genetic toxicity in vivo||Note: testing proposed with Asphalt (EC no. 232-490-9) Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Asphalt (EC no. 232-490-9) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Asphalt (EC no. 232-490-9) Sub-chronic toxicity (90-day): oral||Note: testing proposed with Asphalt (EC no. 232-490-9) |
04/12/2023 04/12/2023 04/12/2023 04/12/2023 |
18/01/2024 18/01/2024 18/01/2024 18/01/2024 |
Details | |
| Residues (petroleum), thermal cracked vacuum | 295-518-9 | 92062-05-0 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
16/08/2011 16/08/2011 |
30/09/2011 30/09/2011 |
Details | |
| dihydro-3-(tripropenyl)furan-2,5-dione | 295-556-6 | 92077-08-2 | Reproductive toxicity (pre-natal developmental toxicity) | 30/09/2015 | 16/11/2015 | Details | |
| Fatty acids, tall-oil, compds. with N-[3-(dimethylamino)propyl]tall-oil amides | 295-714-4 | 92128-22-8 | Long-term toxicity to fish | 03/10/2023 | 17/11/2023 | Details | |
| Fatty acids, tall-oil, compds. with N-[3-(dimethylamino)propyl]tall-oil amides | 295-714-4 | 92128-22-8 | Reproductive toxicity (pre-natal developmental toxicity) | 28/02/2018 | 16/04/2018 | Details | |
| Resin acids and Rosin acids, reaction products with formaldehyde, potassium salt | 295-855-1 | 92129-53-8 | Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin (CAS RN 8050-09-7), Rosin, hydrogenated (CAS RN 65997-06-0), and Rosin, reaction products with formaldehyde (CAS RN 91081-53-7) | 02/07/2013 | 16/08/2013 | Details | |
| Rosin, fumarated, reaction products with glycerol and pentaerythritol | 296-047-1 | 92202-14-7 |
Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7) Reproductive toxicity (two-generation reproductive toxicity) //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4) Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS 94581-15-4) Sub-chronic toxicity (90-day): oral //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6) Sub-chronic toxicity (90-day): oral || Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS 97489-11-7); Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS 94581-15-4); and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS 94581-17-6) |
19/07/2013 19/07/2013 02/07/2013 19/07/2013 02/07/2013 |
02/09/2013 02/09/2013 16/08/2013 02/09/2013 16/08/2013 |
Details | |
| Rosin, fumarated, reaction products with glycerol and pentaerythritol | 296-047-1 | 92202-14-7 | Reproductive toxicity (pre-natal developmental toxicity) | 16/07/2012 | 30/08/2012 | Details | |
| 2-Naphthalenol, 1-[[4-(phenylazo)phenyl]azo]-, ar-heptyl ar',ar''-Me derivs. | 296-120-8 | 92257-31-3 | Genetic toxicity in vivo | 16/12/2020 | 01/02/2021 | Details | |
| Ashes (residues), plant | 297-049-5 | 93333-79-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
| Ashes (residues), plant | 297-049-5 | 93333-79-0 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/05/2011 16/05/2011 16/05/2011 |
30/06/2011 30/06/2011 30/06/2011 |
Details | |
| Hydrocarbons, C4, 1,3-butadiene-free, polymd., tetraisobutylene fraction, hydrogenated | 297-628-2 | - | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
| Hydrocarbons, C4, 1,3-butadiene-free, polymd., triisobutylene fraction, hydrogenated | 297-629-8 | 93685-81-5 | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
| Phosphorous acid, tri-C12-14-alkyl esters | 297-701-9 | 93686-48-7 |
Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) |
16/02/2015 16/02/2015 |
02/04/2015 02/04/2015 |
Details | |
| Alkenes, C15-18 | 297-797-2 | 93762-80-2 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/08/2011 16/08/2011 25/06/2012 |
30/09/2011 30/09/2011 09/08/2012 |
Details | |
| Zinc bis[O-(6-methylheptyl)] bis[O-(sec-butyl)] bis(dithiophosphate) | 298-577-9 | 93819-94-4 |
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0); CAS 68547-79-4) "Testing Proposed according to a plan for the ZDDP category" |
04/10/2018 04/10/2018 04/10/2018 |
19/11/2018 19/11/2018 19/11/2018 |
Details | |
| tripotassium propylsilanetriolate | 299-135-8 | 93857-00-2 |
Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with [trimethoxypropylsilane] (EC 213-926-7) Sub-chronic toxicity (90 day): inhalation
Note: testing proposed with [trimethoxypropylsilane] (EC 213-926-7) |
16/03/2015 16/03/2015 |
30/04/2015 30/04/2015 |
Details | |
| Reaction mass of (E)-3-methyl-5-phenylpent-2-enenitrile and (Z)-3-methyl-5-phenylpent-2-enenitrile | 299-682-2 | 93893-89-1 | Reproductive toxicity (pre-natal developmental toxicity) | 16/12/2020 | 01/02/2021 | Details | |
| Alkenes, C20-24 α- | 300-202-1 | 93924-10-8 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 25/06/2012 |
15/07/2011 15/07/2011 09/08/2012 |
Details | |
| Alkenes, C24-28 α- | 300-203-7 | 93924-11-9 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 25/06/2012 |
15/07/2011 15/07/2011 09/08/2012 |
Details | |
| Gas oils, paraffinic | 300-227-8 | 93924-33-5 | Reproductive toxicity (two-generation reproductive toxicity) | 02/09/2011 | 17/10/2011 | Details | |
| Silicic acid (H4SiO4), tetraethyl ester, reaction products with bis(acetyloxy)dibutylstannane | 300-344-4 | 93925-42-9 | Genetic toxicity in vivo | 21/01/2021 | 08/03/2021 | Details | |
| 3-[[3-[[(2-cyanoethyl)amino]methyl]-3,5,5-trimethylcyclohexyl]amino]propiononitrile | 300-496-1 | 93940-97-7 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
27/01/2020 27/01/2020 |
12/03/2020 12/03/2020 |
Details | |
| (octahydro-4,7-methano-1H-indenyl)methyl acrylate | 300-723-4 | 93962-84-6 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 23/11/2020 | 07/01/2021 | Details | |
| Boric acid (H3BO3), reaction products with ethanolamine | 302-207-4 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/01/2012 16/01/2012 16/01/2012 |
01/03/2012 01/03/2012 01/03/2012 |
Details | |
| Aluminum, benzoate C16-18-fatty acids complexes | 303-385-6 | 94166-87-7 | Reproductive toxicity (pre-natal developmental toxicity) | 25/06/2015 | 10/08/2015 | Details | |
| Trimethyl-3-[(1-oxo-10-undecenyl)amino]propylammonium methyl sulphate | 304-990-8 | 94313-91-4 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Methyl trimethyl-3-[(1-oxododecyl)amino]propylammonium sulphate EC 234-204-8 || Note: Testing proposal is based on concern identified by the registrant | 16/12/2020 | 01/02/2021 | Details | |
| Saccharomyces cerevisiae, lysate | 305-230-8 | 94350-12-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
30/09/2021 30/09/2021 |
15/11/2021 15/11/2021 |
Details | |
| Sodium N-(2-carboxyethyl)-N-(2-ethylhexyl)-β-alaninate | 305-318-6 | 94441-92-6 | Reproductive toxicity (pre-natal developmental toxicity) | 02/06/2014 | 17/07/2014 | Details | |
| Resin acids and Rosin acids, fumarated, esters with pentaerythritol | 305-514-1 | 94581-15-4 | Reproductive toxicity (pre-natal developmental toxicity) | 16/07/2012 | 30/08/2012 | Details | |
| Resin acids and Rosin acids, fumarated, esters with pentaerythritol | 305-514-1 | 94581-15-4 |
Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7) Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7) Reproductive toxicity (two-generation reproductive toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6) Sub-chronic toxicity (90-day): oral || Note: Testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6) |
19/07/2013 02/07/2013 02/07/2013 19/07/2013 19/07/2013 02/07/2013 |
02/09/2013 16/08/2013 16/08/2013 02/09/2013 02/09/2013 16/08/2013 |
Details | |
| Resin acids and Rosin acids, maleated, esters with pentaerythritol | 305-516-2 | 94581-17-6 |
Reproductive toxicity (pre-natal developmental toxicity) //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7) Sub-chronic toxicity (90-day): oral //Note: testing proposed with Resin acids and Rosin acids, fumarated, esters with glycerol (CAS RN 97489-11-7), Resin acids and Rosin acids, fumarated, esters with pentaerythritol (CAS RN 94581-15-4), and Rosin acids and resin acids, maleated, esters with pentaerythritol (CAS RN 94581-17-6) |
19/07/2013 19/07/2013 |
02/09/2013 02/09/2013 |
Details | |
| Rosin, fumarated, reaction products with formaldehyde | 305-795-0 | 95009-65-7 | Reproductive toxicity (pre-natal developmental toxicity) | 06/03/2012 | 20/04/2012 | Details | |
| Rosin, fumarated, reaction products with formaldehyde | 305-795-0 | 95009-65-7 |
Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0). Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and Rosin, maleated (CAS RN 8050-28-0) |
02/07/2013 02/07/2013 |
16/08/2013 16/08/2013 |
Details | |
| Hydrocarbons, C4, 1,3-butadiene- and isobutene-free | 306-004-1 | 95465-89-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
| Fatty acids, C8-10, C12-18-alkyl esters | 306-082-7 | 95912-86-0 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
01/04/2022 01/04/2022 01/04/2022 |
16/05/2022 16/05/2022 16/05/2022 |
Details | |
| Amines, C12-14-tert-alkyl, mixed sec-Bu and iso-Bu phosphates | 306-227-4 | 96690-34-5 | Sub-chronic toxicity (90-day): oral || Note: testing proposed with Amines, C11-14-branched alkyl, monohexyl and dihexyl phosphates (EC 279-632-6) || Note: Testing proposal is based on concern identified by the registrant. | 23/11/2020 | 07/01/2021 | Details | |
| Soybean oil, epoxidized, Me ester, reaction products with propylene glycol | 306-246-8 | 96690-51-6 | Genetic toxicity in vivo | 18/03/2021 | 03/05/2021 | Details | |
| Dodecene, branched | 306-479-5 | 97280-83-6 |
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene), branched (EC no. 500-004-7) Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene), branched (EC no. 500-004-7) Sub-chronic toxicity (90-day): oral||Note: testing proposed with Butene, homopolymer (products derived from either/or But-1-ene/But-2-ene), branched (EC no. 500-004-7) |
06/06/2023 06/06/2023 06/06/2023 |
21/07/2023 21/07/2023 21/07/2023 |
Details | |
| 1,1'-(isopropylidene)bis[3,5-dibromo-4-(2,3-dibromo-2-methylpropoxy)benzene] | 306-832-3 | 97416-84-7 |
Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
01/07/2021 01/07/2021 |
16/08/2021 16/08/2021 |
Details | |