1. ECHA
  2. Consultations
  3. Testing proposals consultation
  4. Previous Testing Proposals

Previous Testing Proposals

Previous Testing Proposals

Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 

Further information

 

For more information on these substances, please go to
Search for chemicals

 

There are currently no ongoing consultations.
Page 26 of 41
50 Items per Page
Showing 1,251 - 1,300 of 2,011 results.
Name
EC Number
CAS Number
Hazard endpoint for which vertebrate testing was proposed
Date of publication to call for available information
Deadline for submitting information
Alternatives to vertebrate testing
 
1,1,4,4-tetramethylbutane-1,4-diyl bis(2-ethylperoxyhexanoate) 235-935-5 13052-09-0 Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates 12/12/2014 26/01/2015 Details
1,10-decanediyl diacrylate 235-922-4 13048-34-5
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Esterification products of acrylic acid with reaction products of 2,2-dimethylpropane-1,3-diol and methyloxirane (EC no. 701-440-2)
Sub-chronic toxicity (90-day): oral||Note: testing proposed with Esterification products of acrylic acid with reaction products of 2,2-dimethylpropane-1,3-diol and methyloxirane (EC no. 701-440-2)
06/06/2023
06/06/2023
06/06/2023
21/07/2023
21/07/2023
21/07/2023
 Details
Phosphoric acid, butyl ester 235-826-2 12788-93-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/04/2015
17/04/2015
04/06/2015
04/06/2015
 Details
Hexaboron dizinc undecaoxide 235-804-2 12767-90-7 Genetic toxicity in vivo

|| Note: Testing proposal is based on concern identified by the registrant. 		25/11/2019 09/01/2020 Details
Hexaboron dizinc undecaoxide 235-804-2 12767-90-7
Carcinogenicity study
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2011
29/04/2011
29/04/2011
29/04/2011
14/06/2011
14/06/2011
14/06/2011
14/06/2011
 Details
Phosphoric acid, 2-ethylhexyl ester 235-741-0 12645-31-7 Reproductive toxicity (pre-natal developmental toxicity) 25/05/2020 09/07/2020 Details
Cyclohexanone, peroxide 235-527-7 12262-58-7 Genetic toxicity in vivo 19/10/2020 03/12/2020 Details
N-(2,3-dihydro-2-oxo-1H-benzimidazol-5-yl)-3-hydroxy-4-[[2-methoxy-5-[(phenylamino)carbonyl]phenyl]azo]naphthalene-2-carboxamide 235-425-2 12225-06-8
7.5.2 Repeated dose toxicity: inhalation
7.8.2 Developmental toxicity / teratogenicity
08/03/2024
08/03/2024
22/04/2024
22/04/2024
 Details
Cobalt lithium dioxide 235-362-0 12190-79-3
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
Sub-chronic toxicity (90 day): inhalation || Note: testing proposed with Tricobalt tetraoxide (EC 215-157-2) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
 Details
barium titanium trioxide 234-975-0 12047-27-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
17/04/2015
17/04/2015
04/06/2015
04/06/2015
 Details
praseodymium(III,IV) oxide 234-857-9 12037-29-5 Genetic toxicity in vivo 18/09/2014 03/11/2014 Details
Vanadium dioxide 234-841-1 12036-21-4
Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: : testing proposed with Sodium metavanadate (EC no. 237-272-7)
Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Sodium metavanadate (EC no. 237-272-7)
16/06/2022
16/06/2022
01/08/2022
01/08/2022
 Details
Cobalt hydroxide oxide 234-614-7 12016-80-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
Cobalt hydroxide oxide 234-614-7 12016-80-7
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Cobalt sulphide (EC 215-273-3) || Note: Testing proposal is based on concern identified by the registrant.
Sub-chronic toxicity (90 day): inhalation || Note: testing proposed with Tricobalt tetraoxide (EC 215-157-2) || Note: Testing proposal is based on concern identified by the registrant
21/09/2020
21/09/2020
21/09/2020
05/11/2020
05/11/2020
05/11/2020
 Details
Dipotassium bis[μ-[tartrato(4-)-O1,O2:O3,O4]]diantimonate(2-) , stereoisomer 234-293-3 11071-15-1
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
 Details
Zinc bis[bis(tetrapropylenephenyl)] bis(hydrogen dithiophosphate) 234-277-6 11059-65-7
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“
04/10/2018
04/10/2018
04/10/2018
19/11/2018
19/11/2018
19/11/2018
 Details
Methyl trimethyl-3-[(1-oxododecyl)amino]propylammonium sulphate 234-204-8 10595-49-0 Reproductive toxicity (pre-natal developmental toxicity) 16/12/2020 01/02/2021 Details
N,N'-dimethyldiphenylthiuram disulphide 234-196-6 10591-84-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2019
16/08/2019
30/09/2019
30/09/2019
 Details
N,N'-bis(3-aminopropyl)ethylenediamine 234-147-9 10563-26-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/03/2021
18/03/2021
03/05/2021
03/05/2021
 Details
Dirhodium trisulphate 234-014-5 10489-46-0 Genetic toxicity in vivo 19/10/2020 03/12/2020 Details
2-aminoethanol, monoester with boric acid 233-829-3 10377-81-8
Long-term or reproductive toxicity to birds
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
01/07/2011
01/07/2011
01/07/2011
15/08/2011
15/08/2011
15/08/2011
 Details
2-aminoethanol, monoester with boric acid 233-829-3 10377-81-8 Sub-chronic toxicity (90-day): oral 17/11/2011 02/01/2012 Details
Bismuth trinitrate 233-791-8 10361-44-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8)
20/09/2013
20/09/2013
04/11/2013
04/11/2013
 Details
Barium chloride 233-788-1 10361-37-2 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018 Details
Barium chloride 233-788-1 10361-37-2
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
29/04/2011
29/04/2011
29/04/2011
14/06/2011
14/06/2011
14/06/2011
 Details
Ethyl 4-dimethylaminobenzoate 233-634-3 10287-53-3
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
10/05/2022
10/05/2022
27/06/2022
27/06/2022
 Details
2,2'-(octadecylimino)bisethanol 233-520-3 10213-78-2 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,2'-(octadec-9-enylimino)bisethanol EC 246-807-3 16/12/2020 01/02/2021 Details
Cobalt (II) dinitrate 233-402-1 10141-05-6
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
cobalt dinitrate 233-402-1 10141-05-6
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4)
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2)
21/01/2021
21/01/2021
08/03/2021
08/03/2021
 Details
Cobalt (II) sulphate 233-334-2 10124-43-3
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity) ; after obtaining results of the 90-day subchronic toxicity study
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
cobalt sulphate 233-334-2 10124-43-3
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4)
Genetic toxicity in vivo
21/01/2021
21/01/2021
08/03/2021
08/03/2021
 Details
cerium trinitrate 233-297-2 10108-73-3 Reproductive toxicity (pre-natal developmental toxicity) 17/04/2015 04/06/2015 Details
Sodium permanganate 233-251-1 10101-50-5 Reproductive toxicity (pre-natal developmental toxicity) 15/04/2011 30/05/2011 Details
a,a-dimethylphenethyl butyrate 233-221-8 10094-34-5
Reproductive toxicity (pre-natal developmental toxicity)“|| Note: testing proposed 1,1-Dimethyl-2-phenylethyl acetate (EC 205-781-3)”
Sub-chronic toxicity (90-day): oral“|| Note: testing proposed 1,1-Dimethyl-2-phenylethyl acetate (EC 205-781-3)”
22/11/2017
22/11/2017
08/01/2018
08/01/2018
 Details
4-(1-methyl-1-phenylethyl)-N-[4-(1-methyl-1-phenylethyl)phenyl]aniline 233-215-5 10081-67-1 Sub-chronic toxicity (90-day): oral 18/02/2014 04/04/2014 Details
Strontium nitrate 233-131-9 10042-76-9
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
31/05/2011
31/05/2011
31/05/2011
15/07/2011
15/07/2011
15/07/2011
 Details
Dipotassium tetrachloroplatinate 233-050-9 10025-99-7 Genetic toxicity in vivo || Note: "Testing proposal is based on concern identified by the registrant." 18/06/2018 02/08/2018 Details
Resin acids and Rosin acids, calcium salts 232-694-8 9007-13-0 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Resin acids and Rosin acids, calcium salts 232-694-8 9007-13-0
Reproductive toxicity (pre-natal developmental toxicity || Note: Testing proposed with Rosin CAS 8050-09-7
Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposed with Rosin CAS 8050-09-7
Sub-chronic toxicity (90-day): oral || Note: Testing proposed with Rosin CAS 8050-09-7, Rosin hydrogenated CAS 65997-06-0, and Rosin reaction products with formaldehyde CAS 91081-53-7
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
 Details
ASPHALT 232-490-9 8052-42-4
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
31/05/2016
31/05/2016
15/07/2016
15/07/2016
 Details
Asphalt 232-490-9 8052-42-4 Reproductive toxicity (extended one-generation reproductive toxicity study)

[note whilst the registrant has selected the drop down of a RaX TPE – it is not a RaX TPE – registered substance is being tested]” 		25/06/2019 09/08/2019 Details
Asphalt 232-490-9 8052-42-4
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
04/12/2023
04/12/2023
04/12/2023
04/12/2023
18/01/2024
18/01/2024
18/01/2024
18/01/2024
 Details
Resin acids and Rosin acids, esters with glycerol 232-482-5 8050-31-5 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Resin acids and Rosin acids, esters with glycerol 232-482-5 8050-31-5
Reproductive toxicity (pre-natal developmental toxicity)|| Note: Testing proposed to be carried out with Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Rosin, ethylene glycol ester (CAS RN 68512-65-2), Rosin, triethylene glycol ester (CAS RN 8050-25-7), Rosin, hydrogenated methyl ester (CAS RN 8050-15-5), Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Rosin, methyl ester (CAS RN 68186-14-1), Rosin, ethylene glycol ester (CAS RN 68512-65-2), Rosin, triethylene glycol ester (CAS RN 8050-25-7)
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
 Details
Rosin, maleated 232-480-4 8050-28-0
Reproductive toxicity (pre-natal developmental toxicity) //Note: to be tested with Rosin, maleated (CAS RN 8050-28-0)
Reproductive toxicity (two-generation reproductive toxicity) //Note: Testing proposed with Rosin, Fumarated (CAS RN 65997-04-7)
Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, fumarated (CAS RN 65997-04-7) and the registered substance
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
 Details
Rosin, maleated 232-480-4 8050-28-0 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Resin acids and Rosin acids, esters with pentaerythritol 232-479-9 8050-26-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (pre-natal developmental toxicity)|| Note: Testing proposed to be carried out with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposed with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5), Rosin, ethylene glycol ester (CAS RN 68512-65-2), Rosin, triethylene glycol ester (CAS RN 8050-25-7) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Sub-chronic toxicity (90-day): oral || Note: Testing proposed with Rosin, methyl ester (CAS RN 68186-14-1), Rosin, ethylene glycol ester (CAS RN 68512-65-2) and Rosin, triethylene glycol ester (CAS RN 8050-25-7)
06/03/2012
02/07/2013
02/07/2013
02/07/2013
20/04/2012
16/08/2013
16/08/2013
16/08/2013
 Details
Resin acids and Rosin acids, esters with triethylene glycol 232-478-3 8050-25-7
Reproductive toxicity (pre-natal developmental toxicity) //Note: Testing proposed with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9)
Reproductive toxicity (two-generation reproductive toxicity) //Note: Testing proposed to be carried out with Rosin, hydrogenated methyl ester (CAS RN 8050-15-5) and Rosin, hydrogenated glycerol ester (CAS RN 65997-13-9) and Rosin, triethylene glycol ester (CAS RN 8050-25-7)
Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, methyl ester (CAS RN 68186-14-1), Rosin, ethylene glycol ester (CAS RN 68512-65-2) and Rosin, triethylene glycol ester (CAS RN 8050-25-7)
02/07/2013
02/07/2013
02/07/2013
16/08/2013
16/08/2013
16/08/2013
 Details
Resin acids and Rosin acids, esters with triethylene glycol 232-478-3 8050-25-7 Reproductive toxicity (pre-natal developmental toxicity) 06/03/2012 20/04/2012 Details
Resin acids and Rosin acids, hydrogenated, Me esters 232-476-2 8050-15-5 Sub-chronic toxicity (90-day): oral //Note: Testing proposed with Rosin, methyl ester (CAS RN 68186-14-1), Rosin, ethylene glycol ester (CAS RN 68512-65-2) and Rosin, triethylene glycol ester (CAS RN 8050-25-7) 02/07/2013 16/08/2013 Details
Page 26 of 41
50 Items per Page
Showing 1,251 - 1,300 of 2,011 results.