Previous Testing Proposals
Previous Testing Proposals
Previous Testing Proposals
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
Further instructions
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
There are currently no ongoing consultations.
| [4-[p,p'-bis(dimethylamino)benzhydrylidene]cyclohexa-2,5-dien-1-ylidene]dimethylammonium m-[[p-anilinophenyl]azo]benzenesulphonate | 265-449-9 | 65113-55-5 |
Genetic toxicity in vivo Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
18/02/2014 18/02/2014 18/02/2014 18/02/2014 |
04/04/2014 04/04/2014 04/04/2014 04/04/2014 |
Details | |
| [[(phosphonomethyl)imino]bis[ethylenenitrilobis(methylene)]]tetrakisphosphonic acid, ammonium salt | 274-798-6 | 70714-66-8 | Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with Sodium salts of [[(phosphonomethyl)imino]bis[ethane-2,1-diylnitrilobis(methylene)]]tetrakisphosphonic acid (5-7 Na:1) (EC no. 701-216-4) | 01/03/2023 | 17/04/2023 | Details | |
| [[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid | 252-156-6 | 34690-00-1 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90-day): oral || Note: Testing proposal is based on concern identified by the registrant. |
20/05/2015 20/05/2015 |
06/07/2015 06/07/2015 |
Details | |
| [[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid | 252-156-6 | 34690-00-1 |
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP Sub-chronic toxicity (90-day): oral || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP |
31/01/2018 31/01/2018 |
19/03/2018 19/03/2018 |
Details | |
| [hexane-1,6-diylbis[nitrilobis(methylene)]]tetrakisphosphonic acid, potassium salt | 254-135-7 | 38820-59-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 |
Details | |
| [No public or meaningful name is available] | 944-258-0 | 1850357-57-1 | Reproductive toxicity (pre-natal developmental toxicity)||Note: testing proposed with Wax, rice bran, oxidized (Polar modified Rice Bran Wax) | 03/05/2023 | 19/06/2023 | Details | |
| A dried sludge product resulting from the treatment process of domestic wastewater. The exact processes followed for the production of the dried sludge are: Preliminary and secondary treatment of the wastewater stream, thickening, dehydration and drying of the excess sludge. | 943-834-9 | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
03/04/2023 03/04/2023 03/04/2023 |
22/05/2023 22/05/2023 22/05/2023 |
Details | |
| A mixture of cis- and trans-cyclohexadec-8-en-1-one | 401-700-2 | 3100-36-5 |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
28/11/2022 28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 12/01/2023 |
Details | |
| A mixture of isomers of branched tetracosane | 417-060-2 | 151006-61-0 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with 1-decene, dimer (EC 917-709-4), Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9), 1-Dodecene, Dimer (EC 814-509-8 ) and Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-Dodecene, dimer, hydrogenated (EC 604-768-3) |
01/07/2021 01/07/2021 01/07/2021 |
16/08/2021 16/08/2021 16/08/2021 |
Details | |
| A mixture of: bis[4-diphenylsulfoniumphenyl]sulfide-bishexafluoroantimonate; thiophenoxyphenylsulfonium hexafluoroantimonate | 403-500-0 | 159120-95-3 | Genetic toxicity in vivo | 03/10/2023 | 17/11/2023 | Details | |
| A mixture of: cis-tetrahydro-2-isobutyl-4-methylpyran-4-ol; trans-tetrahydro-2-isobutyl-4-methylpyran-4-ol | 405-040-6 | 63500-71-0 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 25/06/2015 | 10/08/2015 | Details | |
| a mixture of: cistetrahydro-2-isobutyl-4-methylpyran-4-ol,transtetrahydro-2-isobutyl-4-methylpyran-4-ol | 405-040-6 | 63500-71-0 |
(90-day): oral Reproductive toxicity (developmental toxicity) Sub-chronic toxicity |
20/10/2010 20/10/2010 20/10/2010 |
06/12/2010 06/12/2010 06/12/2010 |
Details | |
| A mixture of: esters of C14-C15 branched alcohols with 3,5-di-t-butyl-4-hydroxyphenyl propionic acid; C15 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate; C13 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate | 413-750-2 | - | Reproductive toxicity (pre-natal developmental toxicity) | 30/09/2021 | 15/11/2021 | Details | |
| A mixture of: tetrasodium-phosphonoethane-1,2-dicarboxylate,hexasodium-phosphonobutane-1,2,3,4-tetracarboxylate | 410-800-5 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
06/03/2012 06/03/2012 |
20/04/2012 20/04/2012 |
Details | |
| A mixture of: triphenylthiophosphate and tertiary butylated phenyl derivatives | 421-820-9 | 192268-65-8 | Long-term toxicity to fish||Note: testing proposed with O,O,O-triphenyl phosphorothioate (EC no. 209-909-9) | 04/12/2023 | 18/01/2024 | Details | |
| A mixture of: α-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyl-ω-hydroxypoly(oxyethylene),α-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyl-ω-3-(3-(2H-benzotriazol-2-yl)-5-tert-butyl-4-hydroxyphenyl)propionyloxypoly(oxyethylene) | 400-830-7 | - | Reproductive toxicity (pre-natal developmental toxicity) | 16/12/2011 | 30/01/2012 | Details | |
| a,a-dimethylphenethyl acetate | 205-781-3 | 151-05-3 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
17/05/2017 17/05/2017 |
03/07/2017 03/07/2017 |
Details | |
| a,a-dimethylphenethyl butyrate | 233-221-8 | 10094-34-5 |
Reproductive toxicity (pre-natal developmental toxicity)“|| Note: testing proposed 1,1-Dimethyl-2-phenylethyl acetate (EC 205-781-3)” Sub-chronic toxicity (90-day): oral“|| Note: testing proposed 1,1-Dimethyl-2-phenylethyl acetate (EC 205-781-3)” |
22/11/2017 22/11/2017 |
08/01/2018 08/01/2018 |
Details | |
| Acetalization products between glucose and C16-18(even numbered)- alcohol | 927-870-2 | - | Sub-chronic toxicity (90-day): oral | 15/09/2011 | 31/10/2011 | Details | |
| Acetalization products between glucose and C20-22(even numbered)- alcohol | 923-835-0 | - | Sub-chronic toxicity (90-day): oral | 15/09/2011 | 31/10/2011 | Details | |
| Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide | 271-794-6 | 68608-66-2 | Long-term toxicity to fish Sub-chronic toxicity (90-day): oral || Note: testing proposed with Reaction products of 1H-Imidazole- 1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0) Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid (EC 931-291-0 | 29/02/2016 | 14/04/2016 | Details | |
| Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide | 271-794-6 | 68608-66-2 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Alkylamidoamine glycinate majority C12, 14 (amphoacetate) EC 931-291-0
|| Note: Testing proposal is based on concern identified by the registrant Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Alkylamidoamine glycinate majority C12, 14 (amphoacetate) EC 931-291-0.
|| Note: Testing proposal is based on concern identified by the registrant |
19/10/2020 19/10/2020 |
03/12/2020 03/12/2020 |
Details | |
| Acetic acid, chloro-, sodium salt, reaction products with 4,5-dihydro-2-undecyl-1H-imidazole-1-ethanol and sodium hydroxide | 271-794-6 | 68608-66-2 | Long-term toxicity to fish | 18/02/2014 | 04/04/2014 | Details | |
| Activated Carbon - High Density Skeleton | 931-328-0 | - | Sub-chronic toxicity (90 day): inhalation | 16/06/2011 | 01/08/2011 | Details | |
| Addition products of m-phenylenebis(methylamine) with reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethyl 5-isocyanato-2-methylphenylcarbamate, 2-(2-(2-butoxyethoxy)ethoxy)ethyl 3-isocyanato-4-methylphenylcarbamate and 2-(2-(2-butoxyethoxy)ethoxy)ethyl 3-isocyanato-2-methylphenylcarbamate | - | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) || Note: Testing proposal is based on potential concern identified by the registrant. Sub-chronic toxicity (90 day): oral |
15/07/2014 15/07/2014 15/07/2014 |
29/08/2014 29/08/2014 29/08/2014 |
Details | |
| Adipic acid | 204-673-3 | 124-04-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 18/02/2021 | 05/04/2021 | Details | |
| Adipohydrazide | 213-999-5 | 1071-93-8 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
31/01/2014 31/01/2014 |
17/03/2014 17/03/2014 |
Details | |
| Alcohols, C11-14-iso-, C13-rich | 271-235-6 | 68526-86-3 | Reproductive toxicity (pre-natal developmental toxicity) | 21/12/2021 | 04/02/2022 | Details | |
| ALCOHOLS, C11-14-ISO-, C13-RICH | 271-235-6 | 68526-86-3 | Sub-chronic toxicity (90-day): oral | 31/05/2016 | 15/07/2016 | Details | |
| Alcohols, C11-14-iso-, C13-rich | 271-235-6 | 68526-86-3 | Reproductive toxicity (pre-natal developmental toxicity) | 27/05/2019 | 11/07/2019 | Details | |
| Alcohols, C12-14, ethoxylated | 500-213-3 | 68439-50-9 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 26/10/2022 | 12/12/2022 | Details | |
| Alcohols, C13-15-branched and linear | 287-625-4 | 85566-16-1 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) |
31/01/2023 31/01/2023 |
17/03/2023 17/03/2023 |
Details | |
| Alcohols, C13-15-branched and linear | 287-625-4 | 85566-16-1 | Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Isotridecan-1-ol (EC 248-469-2) | 16/12/2020 | 01/02/2021 | Details | |
| Alcohols, C16-18 and C18-unsatd., ethoxylated, sulfates, sodium salts | 500-345-1 | 157627-95-7 | Reproductive toxicity (pre-natal developmental toxicity) | 30/06/2023 | 14/08/2023 | Details | |
| Alcohols, C18-22, distn. residues | 641-136-6 | - |
Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/07/2011 15/07/2011 |
29/08/2011 29/08/2011 |
Details | |
| Alcohols, C18-22, distn. residues | 641-136-6 | 1160164-88-4 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |
| Alcohols, C6-8, ethoxylated | 800-182-9 | 1426148-68-6 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
28/11/2022 28/11/2022 |
12/01/2023 12/01/2023 |
Details | |
| ALCOHOLS, C7-9-ISO-, C8-RICH | 271-231-4 | 68526-83-0 | Sub-chronic toxicity (90-day): oral | 31/05/2016 | 15/07/2016 | Details | |
| Alcohols, C8-10, ethoxylated | 615-247-5 | 71060-57-6 |
Long-term toxicity to fish Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) |
22/09/2022 22/09/2022 22/09/2022 |
07/11/2022 07/11/2022 07/11/2022 |
Details | |
| Alcohols, lanolin | 232-430-1 | 8027-33-6 |
Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
| Alkane 6 | 438-390-3 | - |
Reproductive toxicity (extended one-generation reproductive toxicity study
|| Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-decene, dimer (EC 917-709-4) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with 1-Dodecene, Dimer (EC 814-509-8), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with 1-Dodecene, dimer, hydrogenated (EC 604-768-3) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) |
26/08/2021 26/08/2021 26/08/2021 |
11/10/2021 11/10/2021 11/10/2021 |
Details | |
| Alkane-alpha,omega-diyl bis{[(trimethoxysilyl)propyl]carbamate}_M2 | 700-904-1 | 1350725-68-6 | Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Methyl [3-(trimethoxysilyl) propyl]carbamate CAS 23432-62-4 | 02/11/2018 | 17/12/2018 | Details | |
| Alkanes, C10-13, chloro (Short Chain Chlorinated Paraffins) | 287-476-5 | 85535-84-8 | Reproductive toxicity (two-generation reproductive toxicity) | 29/07/2011 | 12/09/2011 | Details | |
| Alkanes, C10-13-iso- | 271-366-9 | 68551-17-7 | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
| Alkanes, C12-14-iso- | 271-369-5 | 68551-19-9 |
Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Hydrocarbons, C7-C9, isoalkanes (EC 921-728-3)
|| Note: testing proposed with Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane (EC 224-506-8) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Hydrocarbons, C7-C9, isoalkanes (EC 921-728-3)
|| Note: testing proposed with Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane (EC 224-506-8) Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Hydrocarbons, C7-C9, isoalkanes (EC 921-728-3)
|| Note: testing proposed with Isohexadecane 2,2,4,4,6,8,8-heptamethylnonane (EC 224-506-8) |
23/11/2020 23/11/2020 23/11/2020 |
07/01/2021 07/01/2021 07/01/2021 |
Details | |
| Alkanes, C12-26-branched and linear | 292-454-3 | 90622-53-0 | Reproductive toxicity (two-generation reproductive toxicity) | 15/09/2011 | 31/10/2011 | Details | |
| Alkanoic acid and polyoxomolybdate borate alkanoate clusters | 944-813-7 | - | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant | 24/08/2020 | 08/10/2020 | Details | |
| Alkenes C20+ | 931-467-7 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 |
Details | |
| Alkenes, C10-13 | 287-479-1 | 85535-87-1 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) |
15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 |
Details | |
| Alkenes, C10-14 | 288-213-7 | 85681-75-0 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
15/09/2011 15/09/2011 25/06/2012 |
31/10/2011 31/10/2011 09/08/2012 |
Details | |