1. ECHA
  2. Consultations
  3. Testing proposals consultation
  4. Previous Testing Proposals

Previous Testing Proposals

Previous Testing Proposals

Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 

Further information

 

For more information on these substances, please go to
Search for chemicals

 

There are currently no ongoing consultations.
Page 11 of 41
50 Items per Page
Showing 501 - 550 of 2,011 results.
Name
EC Number
CAS Number
Hazard endpoint for which vertebrate testing was proposed
Date of publication to call for available information
Deadline for submitting information
Alternatives to vertebrate testing
 
Zinc O,O,O',O'-tetrakis(1,3-dimethylbutyl) bis(phosphorodithioate) 218-679-9 2215-35-2
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with, zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5), and Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Pr) esters, zinc salts (EC 272-723-1), zinc O,O,O',O'-tetrabutyl bis(phosphorodithioate) (EC 230-257-6), Phosphorodithioic acid, mixed O,O-bis(1,3-dimethylbutyl and iso-Pr) esters, zinc salts (EC 283-392-8), and zinc bis[O,O-bis(2-ethylhexyl)] bis(dithiophosphate) (EC 224-235-5)
21/12/2021
21/12/2021
21/12/2021
04/02/2022
04/02/2022
04/02/2022
 Details
butan-2-one O,O',O''-(vinylsilylidyne)trioxime 218-747-8 2224-33-1 Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with Butan-2-one O,O',O''-(methylsilylidyne)trioxime (CAS 22984-54-9). 		25/06/2015 10/08/2015 Details
4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
 Details
4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl 218-760-9 2226-96-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/02/2015
16/02/2015
02/04/2015
02/04/2015
 Details
N-phenyl-N-[(trichloromethyl)thio]benzenesulphonamide 218-915-0 2280-49-1
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
18/02/2014
18/02/2014
04/04/2014
04/04/2014
 Details
Octyl octanoate 218-980-5 2306-88-9
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
03/04/2023
03/04/2023
03/04/2023
22/05/2023
22/05/2023
22/05/2023
 Details
2,4,6,8-tetramethylcyclotetrasiloxane 219-137-4 2370-88-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
 Details
2,4,6,8-tetramethylcyclotetrasiloxane 219-137-4 2370-88-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/05/2020 09/07/2020 Details
2,4,6,8-tetramethylcyclotetrasiloxane 219-137-4 2370-88-9
Sub-chronic toxicity (90-day): oral
-
22/11/2017
22/11/2017
08/01/2018
08/01/2017
 Details
Benzophenone-3,3':4,4'-tetracarboxylic dianhydride 219-348-1 2421-28-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
 Details
2-Hexyldecan-1-ol 219-370-1 2425-77-6 Reproductive toxicity (two-generation reproductive toxicity) 05/04/2011 20/05/2011 Details
1,4-bis(2,3-epoxypropoxy)butane 219-371-7 2425-79-8
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): most appropriate route
14/02/2011
14/02/2011
14/02/2011
31/03/2011
31/03/2011
31/03/2011
 Details
1,4-bis(2,3-epoxypropoxy)butane 219-371-7 2425-79-8 Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with Reaction products of hexane-1,6-diol with 2-(chloromethyl)oxirane (1:2) (EC 618-939-5) 23/03/2020 07/05/2020 Details
11-aminoundecanoic acid 219-417-6 2432-99-7 Reproductive toxicity (developmental toxicity) 08/04/2010 24/05/2010 Details
11-aminoundecanoic acid 219-417-6 2432-99-7 Long-term toxicity to fish 03/10/2023 17/11/2023 Details
2-(2H-benzotriazol-2-yl)-p-cresol 219-470-5 2440-22-4 Bioaccumulation aquatic / sediment 18/06/2018 02/08/2018 Details
1,3,5-Tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione (TGIC) 219-514-3 2451-62-9 Reproductive toxicity (two-generation reproductive toxicity) 19/11/2010 03/01/2011 Details
Strontium bis(2-ethylhexanoate) 219-536-3 2457-02-5 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with [strontium oxide] (EC 215-219-9) 23/11/2020 07/01/2021 Details
3-(trimethoxysilyl)propiononitrile 219-764-3 2526-62-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
21/03/2014
21/03/2014
05/05/2014
05/05/2014
 Details
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane 219-784-2 2530-83-8 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 17/06/2020 03/08/2020 Details
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane 219-784-2 2530-83-8 Genetic toxicity in vivo 16/02/2015 02/04/2015 Details
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane 219-784-2 2530-83-8 Genetic toxicity in vivo 01/08/2012 17/09/2012 Details
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane 219-784-2 2530-83-8
6.1.2 Long-term toxicity to fish
7.8.1 Toxicity to reproduction
08/03/2024
08/03/2024
22/04/2024
22/04/2024
 Details
3-trimethoxysilylpropyl methacrylate 219-785-8 2530-85-0
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study)
01/09/2017
01/09/2017
16/10/2017
16/10/2017
 Details
3-trimethoxysilylpropyl methacrylate 219-785-8 2530-85-0 Reproductive toxicity (pre-natal developmental toxicity) 26/04/2019 10/06/2019 Details
3-trimethoxysilylpropyl methacrylate 219-785-8 2530-85-0
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): inhalation
15/04/2011
15/04/2011
30/05/2011
30/05/2011
 Details
3-chloropropyltrimethoxysilane 219-787-9 2530-87-2
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/08/2021
26/08/2021
11/10/2021
11/10/2021
 Details
2,2'-methylenediphenyl diisocyanate 219-799-4 2536-05-2 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 4,4'-methylenediphenyl diisocyanate (EC no. 202-966-0) 01/04/2022 16/05/2022 Details
Triethoxypropylsilane 219-842-7 2550-02-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): inhalation
03/03/2014
03/03/2014
17/04/2014
17/04/2014
 Details
4-phenylbutan-2-one 219-847-4 2550-26-7 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with a read-across substance having similar formula structure and its carbon chain consists of even number of carbons 22/11/2017 08/01/2018 Details
2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane 219-863-1 2554-06-5
Genetic toxicity in vivo
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): inhalation
03/03/2014
03/03/2014
03/03/2014
03/03/2014
17/04/2014
17/04/2014
17/04/2014
17/04/2014
 Details
Dimethyl 2,2'-azobis(2-methylpropionate) 219-976-6 2589-57-3 Genetic toxicity in vivo 17/06/2020 03/08/2020 Details
[3-(2,3-epoxypropoxy)propyl]triethoxysilane 220-011-6 2602-34-8 Genetic toxicity in vivo 18/03/2021 03/05/2021 Details
1,1,3,3-tetramethyl-1,3-divinyldisiloxane 220-099-6 2627-95-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
25/06/2015
25/06/2015
10/08/2015
10/08/2015
 Details
N-ethyl-2-pyrrolidone (NEP) 220-250-6 2687-91-4
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day) via the inhalatory route
26/01/2011
26/01/2011
14/03/2011
14/03/2011
 Details
Allyl 3-cyclohexylpropionate 220-292-5 2705-87-5 Reproductive toxicity (pre-natal developmental toxicity) 26/10/2022 12/12/2022 Details
Diethyl bis(2-hydroxyethyl)aminomethylphosphonate 220-482-8 2781-11-5 Genetic toxicity in vivo
|| Note: Testing proposal is based on concern identified by the registrant. 		27/01/2020 12/03/2020 Details
4-[[4-(aminocarbonyl)phenyl]azo]-N-(2-ethoxyphenyl)-3-hydroxynaphthalene-2-carboxamide – nano form 220-509-3 2786-76-7 Reproductive toxicity (extended one-generation reproductive toxicity study)||Note: testing proposed with [3-hydroxy-N-(o-tolyl)-4-[(2,4,5-trichlorophenyl)azo]naphthalene-2-carboxamide] (EC no. 229-440-3) 03/10/2023 17/11/2023 Details
N-(1,1-dimethyl-3-oxobutyl)acrylamide 220-713-2 2873-97-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/03/2014
03/03/2014
17/04/2014
17/04/2014
 Details
2,2,6,6-tetramethyl-4-oxopiperidinooxy 220-778-7 2896-70-0 Sub-chronic toxicity (90-day): oral 03/04/2023 22/05/2023 Details
2,2,6,6-tetramethyl-4-oxopiperidinooxy 220-778-7 2896-70-0
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl (CAS No 2226-96-2)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 4-hydroxy-2,2,6,6-tetramethylpiperidinoxyl (CAS No 2226-96-2)
14/08/2014
14/08/2014
28/09/2014
28/09/2014
 Details
[3-(2,3-epoxypropoxy)propyl]diethoxymethylsilane 220-780-8 2897-60-1 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 16/12/2016 30/01/2017 Details
Triethoxyoctylsilane 220-941-2 2943-75-1 Long-term toxicity to fish || Note: testing proposed with Triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1) 17/04/2015 04/06/2015 Details
Triethoxyoctylsilane 220-941-2 2943-75-1
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
27/09/2017
27/09/2017
27/09/2017
13/11/2017
13/11/2017
13/11/2017
 Details
Trimethoxyphenylsilane 221-066-9 2996-92-1 Reproductive toxicity (pre-natal developmental toxicity) 03/03/2014 17/04/2014 Details
2,2'-azobis[2-methylpropionamidine] dihydrochloride 221-070-0 2997-92-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
05/07/2018
05/07/2018
20/08/2018
20/08/2018
 Details
3,9-dimethyl-2,4,8,10-tetraoxa-3,9-diphosphaspiro[5.5]undecane 3,9-dioxide 221-088-9 3001-98-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/12/2020
16/12/2020
01/02/2021
01/02/2021
 Details
tert-butyl 2-ethylperoxyhexanoate 221-110-7 3006-82-4
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2011
15/04/2011
15/04/2011
30/05/2011
30/05/2011
30/05/2011
 Details
Cyclohexylidenebis[tert-butyl] peroxide 221-111-2 3006-86-8 Sub-chronic toxicity (90-day): oral 21/03/2014 05/05/2014 Details
bis(2-dimethylaminoethyl)(methyl)amine 221-201-1 3030-47-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/03/2014
03/03/2014
17/04/2014
17/04/2014
 Details
Page 11 of 41
50 Items per Page
Showing 501 - 550 of 2,011 results.