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Previous Testing Proposals

Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
Phosphorodithioic acid, mixed O,O-bis(2-ethylhexyl and iso-Bu and iso-Pr) esters, zinc salts 288-917-4 85940-28-9
"Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) ""Testing proposed according to a plan for the ZDDP category.“ "
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category"
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“
04/10/2018
04/10/2018
04/10/2018
19/11/2018
19/11/2018
19/11/2018
a mixture of: cistetrahydro-2-isobutyl-4-methylpyran-4-ol,transtetrahydro-2-isobutyl-4-methylpyran-4-ol 405-040-6 63500-71-0
(90-day): oral
Reproductive toxicity (developmental toxicity)
Sub-chronic toxicity
20/10/2010
20/10/2010
20/10/2010
06/12/2010
06/12/2010
06/12/2010
Coupling reaction products of diazotized 2-amino-6-[(2-substituted ethyl)sulfonyl]naphthalene-1-subsituted acid with 4-({4-chloro-6-[ethyl(3-{[2-(substituted oxy)ethyl]sulfonyl}phenyl)amino]-heteromonocycl-2-yl}amino)-5-hydroxynaphthalene-2,7-disubstituted acid and their sodium and potassium salts - - 7.6.2 Mammalian erythrocyte micronucleus test according to OECD 474 03/12/2010 17/01/2011
1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-nortall-oil alkyl derivs. 263-171-2 61791-39-7 Bioaccumulation aquatic / sediment 16/05/2014 30/06/2014
2,6,10,15,19,23-hexamethyltetracosane 203-825-6 111-01-3 Bioaccumulation aquatic / sediment 14/08/2014 28/09/2014
2-(2H-benzotriazol-2-yl)-4,6-bis(1-methyl-1-phenylethyl)phenol 274-570-6 70321-86-7 Bioaccumulation aquatic / sediment 15/07/2014 29/08/2014
2-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol 221-573-5 3147-75-9 Bioaccumulation aquatic / sediment 15/07/2014 29/08/2014
2-(2H-benzotriazol-2-yl)-p-cresol 219-470-5 2440-22-4 Bioaccumulation aquatic / sediment 18/06/2018 02/08/2018
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2 Bioaccumulation aquatic / sediment 12/06/2015 27/07/2015
Bumetrizole 223-445-4 3896-11-5 Bioaccumulation aquatic / sediment 18/06/2018 02/08/2018
C8-C26 branched and linear hydrocarbons - Distillates 481-740-5 848301-67-7 Bioaccumulation aquatic / sediment 11/05/2010 25/06/2010
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide 229-782-3 6731-36-8 Bioaccumulation aquatic / sediment 25/06/2019 09/08/2019
Hexafluoropropene, oxidized, oligomers, reduced, fluorinated 500-537-5 161075-00-9 Bioaccumulation aquatic / sediment 16/10/2014 01/12/2014
Isodecyl diphenyl phosphate 249-828-6 29761-21-5 Bioaccumulation aquatic / sediment 15/07/2011 29/08/2011
Methylene-bis-4,1-(N-phenylene-N'-butylurea) 416-600-4 - Bioaccumulation aquatic / sediment 17/05/2016 01/07/2016
Polysulfides, di-tert-Bu 273-103-3 68937-96-2 Bioaccumulation aquatic / sediment 01/07/2011 15/08/2011
Polysulfides, di-tert-dodecyl 270-335-7 68425-15-0 Bioaccumulation aquatic / sediment 16/02/2015 02/04/2015
Polysulfides, di-tert-dodecyl 270-335-7 68425-15-0 Bioaccumulation aquatic / sediment 01/07/2011 15/08/2011
Trixylyl phosphate 246-677-8 25155-23-1 Bioaccumulation aquatic / sediment 02/09/2011 17/10/2011
hexamolybdenum(3+) tris((dioctylcarbamothioyl)sulfanide) tris((ditridecylcarbamothioyl)sulfanide) hexahydrate hexasulfanediide 441-570-4 -
Bioaccumulation aquatic / sediment || Note: Link to registration dossier not given as the dossier not yet disseminated.
Reproductive toxicity (pre-natal developmental toxicity) || Note: Link to registration dossier not given as the dossier not yet disseminated.
Sub-chronic toxicity (90-day): oral || Note: Link to registration dossier not given as the dossier not yet disseminated.
10/12/2018
10/12/2018
10/12/2018
24/01/2019
24/01/2019
24/01/2019
4,4'-(9H-fluoren-9-ylidene)bis(2-chloroaniline) 407-560-9 107934-68-9 Bioaccumulation aquatic / sediment || Note: Testing proposal is based on concern identified by the registrant. 16/10/2014 01/12/2014
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated 941-216-3 -
Bioaccumulation aquatic / sediment || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated, Distillation Residue 941-212-1 -
Bioaccumulation aquatic / sediment || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade).
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade).
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade). Testing proposal is based on concern identified by the registrant.
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Cashew Nutshell Extract, Decarboxylated, Distilled (Distilled Grade).
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
1,4-phenylene bis[(4-phenoxyphenyl)-methanone] 620-097-9 54299-17-1
Bioaccumulation aquatic / sediment
Long-term toxicity to fish
22/11/2017
22/11/2017
08/01/2018
08/01/2018
Tall oil, maleated 268-859-6 68152-93-2
Bioaccumulation aquatic / sediment
Long-term toxicity to fish
04/10/2018
04/10/2018
19/11/2018
19/11/2018
Phenol, isopropylated, phosphate (3:1) 273-066-3 68937-41-7
Bioaccumulation aquatic / sediment
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
29/07/2011
29/07/2011
29/07/2011
29/07/2011
29/07/2011
12/09/2011
12/09/2011
12/09/2011
12/09/2011
12/09/2011
Bis(2-ethylhexyl) fumarate 205-448-2 141-02-6
Bioaccumulation aquatic / sediment
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
14/02/2011
14/02/2011
14/02/2011
31/03/2011
31/03/2011
31/03/2011
Phosphorous acid, tri-C12-14-alkyl esters 297-701-9 93686-48-7
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
16/02/2015
16/02/2015
02/04/2015
02/04/2015
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 218-664-7 2212-81-9
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant
20/10/2016
20/10/2016
05/12/2016
05/12/2016
Cashew (Anacardium occidentale) Nutshell Extract, Decarboxylated, Distilled - -
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
Cashew, nutshell liq. 232-355-4 8007-24-7
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
15/09/2011
15/09/2011
15/09/2011
15/09/2011
31/10/2011
31/10/2011
31/10/2011
31/10/2011
2,3-Epoxypropyl neodecanoate, oligomeric reaction products with toluene-4-sulfonic acid 500-281-4 98362-33-5
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
6'-(dibutylamino)-3'-methyl-2'-(phenylamino)spiro[isobenzofuran-1(3H),9-(9H)-xanthen]-3-one 403-830-5 89331-94-2
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
23/04/2018
23/04/2018
23/04/2018
07/06/2018
07/06/2018
07/06/2018
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 246-678-3 25155-25-3
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
06/03/2012
06/03/2012
06/03/2012
20/04/2012
20/04/2012
20/04/2012
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 218-664-7 2212-81-9
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2012
16/05/2012
16/05/2012
02/07/2012
02/07/2012
02/07/2012
Alcohols, lanolin 232-430-1 8027-33-6
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Condensation product of N-C12-C18- alkylpropane-1,3-diamine, N-(3- aminopropyl)-N'-C12-C18- alkylpropane-1,3-diamine and formic acid 641-088-6 -
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2011
16/08/2011
16/08/2011
30/09/2011
30/09/2011
30/09/2011
N-[2-(piperazin-1-yl)ethyl]C18-unsatured-alkylamide 629-767-5 -
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/07/2011
15/07/2011
15/07/2011
29/08/2011
29/08/2011
29/08/2011
tetradecahydro-7-isopropyl-1,4a-dimethylphenanthren-1-methanol 236-476-3 13393-93-6
Bioaccumulation aquatic / sediment
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
18/02/2014
04/04/2014
04/04/2014
04/04/2014
N-(cyclohexylthio)phthalimide 241-774-1 17796-82-6
Bioaccumulation: aquatic / sediment
Long-term or reproductive toxicity to birds
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
01/07/2011
01/07/2011
01/07/2011
01/07/2011
17/12/2012
15/08/2011
15/08/2011
15/08/2011
15/08/2011
31/01/2013
Tris(methylphenyl) phosphate 215-548-8 1330-78-5
Bioaccumulation: aquatic / sediment;
Long-term toxicity to fish
02/09/2011
02/09/2011
17/10/2011
17/10/2011
bis(4-chlorophenyl) sulphone 201-247-9 80-07-9
Bioaccumulation: terrestrial
Reproductive toxicity (pre-natal developmental toxicity)
15/04/2011
15/04/2011
30/05/2011
30/05/2011
Hexaboron dizinc undecaoxide 235-804-2 12767-90-7
Carcinogenicity study
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2011
29/04/2011
29/04/2011
29/04/2011
14/06/2011
14/06/2011
14/06/2011
14/06/2011
Oxalaldehyde 203-474-9 107-22-2
Chronic toxicity / carcinogenicity
Reproductive toxicity (two-generation reproductive toxicity)
05/04/2011
05/04/2011
20/05/2011
20/05/2011
2-piperazin-1-ylethylamine 205-411-0 140-31-8
Chronic toxicity/carcinogenicity
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
14/02/2011
14/02/2011
14/02/2011
31/03/2011
31/03/2011
31/03/2011
Ethylene dibenzoate 202-338-6 94-49-5
Developmental neurotoxicity
Reproductive toxicity (pre-natal developmental toxicity 
21/05/2018
21/05/2018
05/07/2018
05/07/2018
3-[(diisoalkyloxyphosphorothioyl)thio]-2-methylalkanoic acid - - Developmental toxicity (pre-natal developmental toxicity) 15/03/2011 29/04/2011
Hexahydro-1,3,5-trimethyl-1,3,5-triazine 203-612-8 108-74-7 Genetic toxicity - EU Method B.12 11/01/2011 25/02/2011
(chloromethyl)triethoxysilane 239-311-3 15267-95-5 Genetic toxicity in vivo 16/10/2014 01/12/2014
1-bromopropane (n-propyl bromide) 203-445-0 106-94-5 Genetic toxicity in vivo 15/04/2011 30/05/2011



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