Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



No results were found
Details
4,4'-methylene bis(3-chloro-2,6-di-ethylphenylisocyanate)
420-530-1 - No longer Valid NONS Individual No longer valid 15-12-2008 View substance registered dossier
4,4'-methylenediphenyl diisocyanate and its oligomeric reaction products with oxydipropanol and [(methylethylene)bis(oxy)]dipropanol
701-072-2 - Active Full Joint ≥ 1 000 to < 10 000 tonnes 24-08-2022 View substance registered dossier
4,4'-methylenediphenyldiisocyanate and 2,4'-diisocyanatodiphenylmethane and their oligomerisation reaction products with 2,2'-oxydiethanol, propane-1,2-diol and butane-1,3-diol
701-276-1 - Cease Manufacture Full Joint Cease manufacture 13-02-2019 View substance registered dossier
4,4'-Sulfonylbisphenol polymer with 1,1'-oxybis[2-chloroethane]
427-620-8 - Active NONS Joint Tonnage data confidential 05-09-2019 View substance registered dossier
4,4,19,19-tetraethoxy-3,20-dioxa-8,15-dithia-4,19-disiladocosaneand S-(6-{[3-(triethoxysilyl)propyl]thio}hexyl) ethanethioate
951-696-6 - Active Full Joint ≥ 1 to < 10 tonnes 22-02-2021 View substance registered dossier
4,4’-isopropylidenediphenol, reaction products with 1-chloro-2,3-epoxypropane, mono, di and triesters with acrylic acid
948-054-2 - Active Full Joint ≥ 0 to < 10 tonnes 13-01-2023 View substance registered dossier
4,5-di-tert-butyl-6-ethoxy-2,2-dimethyl-3,7-dioxa-4-aza-6-phosphanonan-1-oic acid 6-oxide
449-920-8 - Active NONS Individual Tonnage data confidential 16-12-2010 View substance registered dossier
4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol
443-400-4 - Active Intermediate Joint Intermediate use only 20-08-2018 View substance registered dossier
4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol
443-400-4 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4,5-dihydro-5-oxo-1-(4-sulfophenyl)-4-(4-{2-[1,2,7,8-tetrahydro-7-(4-nitro-2-sulfophenylhydrazono)-1,8-dioxo-3,6-disulfo-2-naphthylidene]hydrazino}-3-sulfophenylhydrazono)pyrazole-3-carboxylic acid, lithium sodium salt
445-080-1 - No longer Valid NONS Individual No longer valid 24-11-2010 View substance registered dossier
4,5-dihydro-5-oxo-1-(4-sulfophenyl)-4-(4-{2-[1,2,7,8-tetrahydro-7-(4-nitro-2-sulfophenylhydrazono)-1,8-dioxo-3,6-disulfo-2-naphthylidene]hydrazino}-3-sulfophenylhydrazono)pyrazole-3-carboxylic acid, lithium sodium salt
445-080-1 - Active NONS Individual Tonnage data confidential 29-04-2021 View substance registered dossier
4,6-bis[2-(4-hydroxyphenyl)isopropylidene]resorcinol
HBPX-1
432-380-2 - Active NONS Joint Tonnage data confidential 27-11-2012 View substance registered dossier
4,6-Dichloro-5-fluoropyrimidine
446-560-3 - Active Intermediate Joint Intermediate use only 30-06-2022 View substance registered dossier
4,7-methanooctahydro-1H-indene-diyldimethyl bis(2-carboxybenzoate)
TCD EMULGATOR
407-410-2 - Active Full Individual ≥ 100 to < 1 000 tonnes 08-12-2016 View substance registered dossier
4,7-methanooctahydro-1H-indene-diyldimethyl bis(2-carboxybenzoate)
TCD EMULGATOR
407-410-2 - Active NONS Joint Tonnage data confidential 09-11-2011 View substance registered dossier
4-(1-((3-((2-(tert-butoxycarbonyl(methyl)amino)acetoxy)methyl)pyridin-2-yl)(methyl)carbamoyloxy)ethyl)-1-((2R,3S)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-1H-1,2,4-triazol-4-ium sulphate
926-418-1 - Active Intermediate Individual Intermediate use only 09-05-2018 View substance registered dossier
4-(2-aminoethyl)indole, fumarate
947-445-5 - Active Intermediate Joint Intermediate use only 07-05-2018 View substance registered dossier
4-(2-Hydroxyethyl)indolin-2-one
925-636-4 - Active Intermediate Individual Intermediate use only 08-03-2021 View substance registered dossier
4-(3,4-dichlorophenyl)tetralin-1-one
406-300-1 - Active Intermediate Joint Intermediate use only 15-02-2018 View substance registered dossier
4-(3,4-dichlorophenyl)tetralin-1-one
406-300-1 - Active Intermediate Joint Intermediate use only 25-07-2021 View substance registered dossier
4-(3,4-dichlorophenyl)tetralin-1-one
406-300-1 - Active NONS Joint Tonnage data confidential 20-08-2010 View substance registered dossier
4-(4'-Trifluoromethylphenyl)benzaldehyde
473-430-3 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butynyl)-α,α-dimethylbenzeneacetic acid
462-560-6 - No longer Valid Intermediate Individual No longer valid 10-05-2011 View substance registered dossier
4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butynyl)-α,α-dimethylbenzeneacetic acid
462-560-6 - Active Intermediate Joint Intermediate use only 06-07-2015 View substance registered dossier
4-(4-Brom-5-ethyl-tetrahydropyran-2-yl)-phenol
919-822-4 - Active Intermediate Joint Intermediate use only 25-05-2018 View substance registered dossier
4-(4-Brom-5-propyl-tetrahydropyran-2-yl)-phenol
917-991-9 - Active Intermediate Joint Intermediate use only 16-02-2018 View substance registered dossier
4-(4-chloro-3-nitro-phenyl)-3-methyl-4-oxo-butanoic acid
918-019-6 - Active Intermediate Joint Intermediate use only 31-05-2018 View substance registered dossier
4-(4-chlorophenyl)-1-imidazol-1-ylbutan-2-ol
925-590-5 - Active Intermediate Joint Intermediate use only 16-01-2017 View substance registered dossier
4-(4-hydroxyphenyl)cyclohexanone
4-(4'-HYDROXYPHENYL)-CYCLOHEXANON
423-920-8 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-(4-trans-propylcylohexyl)phenol
PCH-3-PHENOL
440-740-5 - Active Intermediate Joint Intermediate use only 20-12-2019 View substance registered dossier
4-(4-trans-vinyl-[1,1'-bicyclohexyl]-4'-trans-yl)-1,2-difluorobenzene
430-860-6 - Active NONS Individual Tonnage data confidential 05-11-2019 View substance registered dossier
4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)-N-(2-ethyl-3-oxo-1,2-oxazolidin-4-yl)-2-methylbenzamide
954-921-6 - Active Full Joint ≥ 0 to < 10 tonnes 04-04-2023 View substance registered dossier
4-(5-(5-[1-(4-carboxyphenyl)hexahydro-2,4,6-trioxopyrimidin-5-ylidene]penta-1,3-dienyl)-1,2,3,4-tetrahydro-6-hydroxy-2,4-dioxopyrimidin-1-yl)benzoic acid-triethylamine salt
426-900-7 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-(5-ethoxyheptyl)perhydropentalen-2-one
ETHOCYN
419-880-6 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
4-(5-Ethyl-tetrahydropyran-2-yl)-phenol
921-114-5 - Active Full Joint ≥ 0 to < 10 tonnes 23-10-2020 View substance registered dossier
4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide
VALDECOXIB
448-010-8 - Active Intermediate Joint Intermediate use only 20-08-2018 View substance registered dossier
4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide
VALDECOXIB
448-010-8 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
4-(5-Propyl-tetrahydropyran-2-yl)-phenol
919-949-5 - Active Full Joint ≥ 0 to < 10 tonnes 17-12-2021 View substance registered dossier
4-(6-(3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile bis sulphate
951-814-6 - Active Intermediate Individual Intermediate use only 03-01-2020 View substance registered dossier
4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester)
425-880-7 - Active Full Joint ≥ 1 to < 10 tonnes 21-05-2019 View substance registered dossier
4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester)
425-880-7 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
4-(Difluoro-(3,4,5-trifluoro-phenoxy)-methyl)-3,5-difluoro-benzaldehyde
942-738-4 - Active Full Joint ≥ 0 to < 10 tonnes 18-10-2022 View substance registered dossier
4-(nitromethyl)-1-(2-phenylethyl)piperidin-4-ol;hydrochloride
928-867-9 - Active Intermediate Joint Intermediate use only 14-02-2017 View substance registered dossier
4-(trans-4-Propylcyclohexyl)-1-bromobenzene
485-340-1 - Active Intermediate Joint Intermediate use only 19-11-2019 View substance registered dossier
4-(trans-4-propylcyclohexyl)phenyl acetic acid
PCH-3-ESSIGSÄURE
435-100-7 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
4-({6-AMINO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE
458-850-7 - Active NONS Joint Tonnage data confidential 23-05-2018 View substance registered dossier
4-[(4,6-bis{[3-(diethylamino)propyl]amino}-heteromonocycle-2-yl)amino]-N-[2-(4,5,6,7-tetrachloro-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)quinolin-8-yl]benzenesulfonamide
- - Active Full Individual ≥ 1 to < 10 tonnes 05-10-2011 View substance registered dossier
4-[(4-(aminoiminomethyl)phenyl)amino]-4-oxobutanoic acid hydrochloride
ABAS
430-340-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-[(4-Fluorophenylimino)methyl]phenol
438-950-7 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-[(4-Fluorophenylimino)methyl]phenol
438-950-7 - Active Intermediate Joint Intermediate use only 25-07-2019 View substance registered dossier
4-[(4-{[4-({5-[2-(acryloyloxy) ethoxy]-5-oxoalkanoyl}oxy) benzoyl]oxy}-2-methylaroxy)carbonyl] aryl 2-(acryloyloxy) ethyl alkandioate
- - Active Full Joint Tonnage data confidential 04-12-2017 View substance registered dossier
4-[(6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile
928-806-6 - Active Full Joint ≥ 1 to < 10 tonnes 29-05-2018 View substance registered dossier
4-[({(3R,3aR,6S,6aR)-6-[(4-{[4-({[4-(acryloyloxy)butoxy]carbonyl}oxy)benzoyl]oxy}benzoyl)oxy]hexahydrofuro[3,2-b]furan-3-yl}oxy)carbonyl]phenyl 4-({[4-(acryloyloxy)butoxy]carbonyl}oxy)benzoate
431-360-0 - Active NONS Individual Tonnage data confidential 02-08-2011 View substance registered dossier
4-[2-((6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-ylsulfanyl)thiazole-4-yl]-1-methyl-pyridiniumchloride monohydrochloride
AMPA
447-990-4 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-[2-((6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-ylsulfanyl)thiazole-4-yl]-1-methyl-pyridiniumchloride monohydrochloride
AMPA
447-990-4 - Active Intermediate Joint Intermediate use only 16-10-2019 View substance registered dossier
4-[2-(4-hydroxyphenyl)propan-2-yl]phenol, reaction product with diphenyl carbonate
926-571-4 - Active Full Joint ≥ 100 to < 1 000 tonnes 30-10-2020 View substance registered dossier
4-[2-(Cyclopropylmethoxy)ethyl]phenol
440-910-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-[2-(Cyclopropylmethoxy)ethyl]phenol
440-910-9 - Active Intermediate Joint Intermediate use only 12-10-2018 View substance registered dossier
4-[2-[(E)-2-[(3E)-2-chloro-3-[(2E)-2-[1,1-dimethyl-3-(4-sulfobutyl)benzo[e]indol-2-ylidene]ethylidene]inden-1-yl]vinyl]-1,1-dimethyl-benzo[e]indol-3-ium-3-yl]butane-1-sulfonate
942-705-4 - Active Full Individual ≥ 1 to < 10 tonnes 14-06-2016 View substance registered dossier
4-[4-[4-[(3R, 5R)[5-(2,4-difluorophenyl) tetrahydro-5-(1H-1,2,4-triazol-1-yl-methyl)-furan-3-yl]methyloxy]phenyl]-1-piperazinyl]phenyl-2-[(1S,2S)(1-ethyl-2-phenylmethoxypropyl)]-2,4-dihydro-3Htriazol-3-one
938-153-9 - Active Full Joint ≥ 1 to < 10 tonnes 27-06-2017 View substance registered dossier
4-[bis(2-tert-butyl-4-hydroxy-6-methylphenyl)methyl]phenyl 6-diazo-5-oxo-5,6-dihydronaphthalene-1-sulfonate
451-040-4 - Active NONS Individual Tonnage data confidential 27-11-2012 View substance registered dossier
4-[bis(phenylsubstituted)substituted]phthalic acid
- - Active Full Joint ≥ 1 to < 10 tonnes 02-06-2020 View substance registered dossier
4-[difluoro(3,4,5-trifluorophenoxy)methyl]-2',3,5-trifluoro-4''-pentyl-1,1':4',1''-terphenyl
935-977-0 - Active Full Joint ≥ 0 to < 10 tonnes 16-10-2019 View substance registered dossier
4-acetilammino-N-((1-etil-2pirrolidinil)metil) -5 etilsulfonil-2-metossi benzamide
925-003-2 - Active Intermediate Joint Intermediate use only 27-03-2018 View substance registered dossier
4-acetyloxy-5β,20-epoxy-1,2α,4,7β,10β,13α-hexahydroxy-9-oxotax-11-en-2-yl benzoate
10-DEACETYLBACCATIN III
418-680-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-amino-1-Methyl-3-n-propyl-5-pyrazolecarboxamide hydrochloride
938-723-7 - Active Intermediate Joint Intermediate use only 19-07-2021 View substance registered dossier
4-Amino-2,3-dichlorophenol
464-070-8 - Active Intermediate Joint Intermediate use only 28-09-2021 View substance registered dossier
4-Amino-5-chloro-2,1,3-benzothiodiazole
457-490-8 - Active Intermediate Individual Intermediate use only 01-04-2015 View substance registered dossier
4-amino-5-ethyl-1-(2-methoxyethyl)-1H-Pyrazole-3-carboxamide
438-910-9 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
4-azidobutan-1-amine; (7,7-dimethyl-3-oxo-4-bicyclo[2.2.1]heptanyl)methanesulfonic acid
943-084-2 - Active Intermediate Individual Intermediate use only 10-03-2016 View substance registered dossier
4-bromo-2,3',4',5'-tetrafluoro-1,1'-biphenyl
936-926-5 - Active Intermediate Joint Intermediate use only 19-02-2018 View substance registered dossier
4-butoxy-2,2,6,6-tetramethyl-1-piperidinyloxy
482-430-2 - Active Full Individual ≥ 0 to < 10 tonnes 24-03-2021 View substance registered dossier
4-Butoxy-2,3-difluor-4'-methyl-1,1'-biphenyl
938-422-0 - Active Full Joint ≥ 0 to < 10 tonnes 13-05-2019 View substance registered dossier
4-chloro-6-methoxypyrimidine
435-030-7 - Active Intermediate Individual Intermediate use only 29-09-2022 View substance registered dossier
4-chloromethyl-4''-ethyl-2'-fluoro-[1,1':4',1''-terphenyl]
936-119-8 - Active Full Joint ≥ 1 to < 10 tonnes 05-07-2022 View substance registered dossier
4-cis-ethyl-4'-trans-propyl-[1,1'-bicyclohexyl]
935-545-1 - Active Intermediate Joint Intermediate use only 19-02-2018 View substance registered dossier
4-CPH
428-130-7 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-Cyclohexan-1-ol, dodecyl-, branched
938-702-2 - Active Full Individual ≥ 1 to < 10 tonnes 19-04-2021 View substance registered dossier
4-ethoxy-2,3-difluoro-4'-(trans-4-propylcyclohexyl)-1,1'-biphenyl
921-136-5 - Active Full Joint ≥ 0 to < 10 tonnes 09-12-2022 View substance registered dossier
4-ethoxy-2,6-di(nonyl)-1,3-dioxane
920-431-6 - Active Intermediate Joint Intermediate use only 16-02-2021 View substance registered dossier
4-ethyl-1,3-dioxolan-2-one
JEFFSOL BUTYLENE CARBONATE; TEXACAR F-100
403-780-4 - Active NONS Joint Tonnage data confidential 01-02-2011 View substance registered dossier
4-ethyl-2-fluoro-4'-(2-(trans-4-propylcyclohexyl)ethyl)biphenyl
LICRISTAL I 32 (IS 1156)
433-190-2 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
4-Ethyl-3'-fluorobiphenyl
918-150-9 - Active Intermediate Joint Intermediate use only 31-03-2021 View substance registered dossier
4-Fluoro-3-hydroxybenzoic acid
434-190-5 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
4-Fluoro-3-hydroxybenzoic acid
434-190-5 - Active Intermediate Joint Intermediate use only 28-08-2019 View substance registered dossier
4-fluoro-N-(propan-2-yl)aniline
448-100-7 - Active Intermediate Joint Intermediate use only 13-05-2022 View substance registered dossier
4-hydroxy-3-methyl-5-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]pentan-2-one
949-712-1 - Active Intermediate Joint Intermediate use only 11-02-2019 View substance registered dossier
4-hydroxybutan-2-one + 3-(hydroxymethyl)but-3-en-2-one
908-868-0 - Active Intermediate Joint Intermediate use only 22-01-2020 View substance registered dossier
4-hydroxybutane-1-sulfonic acid
928-903-3 - Active Intermediate Individual Intermediate use only 29-04-2015 View substance registered dossier
4-hydroxyphenyl 4-(allyloxy)benzoate
4-ALLYLOXYBENZOESÄUREHYDROCHINONESTER
433-210-1 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-hydroxystyrene, 4-tbutoxy styrene and styrene copolymer
433-660-7 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-Isobutylbenzaldehyde
464-400-0 - Active NONS Joint Tonnage data confidential 22-07-2014 View substance registered dossier
4-Methoxy-5-(3-morpholin-4-yl-propoxy)-2-nitro-benzonitrile
936-067-6 - Cease Manufacture Intermediate Joint Cease manufacture 24-10-2017 View substance registered dossier
4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
GCLE
403-040-0 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
GCLE
403-040-0 - Active Intermediate Individual Intermediate use only 16-11-2011 View substance registered dossier
4-Methoxycarbonyl-2-methylthiophen-3-yl-ammonium hydrochloride
929-732-7 - Active Intermediate Joint Intermediate use only 21-02-2013 View substance registered dossier
4-methoxycyclohexanone
480-410-8 - Active Intermediate Joint Intermediate use only 11-11-2022 View substance registered dossier
4-Methyl-2-propylbenzimidazole-6-carboxylic acid
424-450-6 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
4-Methyl-2-propylbenzimidazole-6-carboxylic acid
424-450-6 - Active Intermediate Individual Intermediate use only 21-04-2010 View substance registered dossier
4-methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-amine hydrobromide
946-432-1 - Active Intermediate Individual Intermediate use only 09-01-2018 View substance registered dossier
No results were found
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Lonza Biologics PLC The Courtyard, Severn Drive GL20 8GD Tewkesbury Gloucestershire United Kingdom United Kingdom No longer Valid 4,4'-methylene bis(3-chloro-2,6-di-ethylphenylisocyanate) 420-530-1 - 2021 View substance registered dossier
Rohm and Haas Italia Srl Via Trieste 25 22076 Mozzate Como Italy Italy Active 4,4'-methylenediphenyl diisocyanate and its oligomeric reaction products with oxydipropanol and [(methylethylene)bis(oxy)]dipropanol 701-072-2 - 2019; 2022 View substance registered dossier
DOW BENELUX B.V. Postbus 48 4530 AA Terneuzen Netherlands Netherlands Active 4,4'-methylenediphenyl diisocyanate and its oligomeric reaction products with oxydipropanol and [(methylethylene)bis(oxy)]dipropanol 701-072-2 - 2012; 2014; 2016; 2017; 2019; 2021; 2022 View substance registered dossier
DOW DEUTSCHLAND ANLAGENGESELLSCHAFT mbH Buetzflether Sand 2 D-21683 Stade Germany Germany Active 4,4'-methylenediphenyl diisocyanate and its oligomeric reaction products with oxydipropanol and [(methylethylene)bis(oxy)]dipropanol 701-072-2 - 2022 View substance registered dossier
BASF Polyurethanes GmbH Elastogranstr. 60 49448 Lemförde Niedersachsen Germany Germany Cease Manufacture 4,4'-methylenediphenyldiisocyanate and 2,4'-diisocyanatodiphenylmethane and their oligomerisation reaction products with 2,2'-oxydiethanol, propane-1,2-diol and butane-1,3-diol 701-276-1 - 2020 View substance registered dossier
BASF Espanola S.L. Calle Can Ràbia, n. 3-5 8017 Barcelona Spain Spain Cease Manufacture 4,4'-methylenediphenyldiisocyanate and 2,4'-diisocyanatodiphenylmethane and their oligomerisation reaction products with 2,2'-oxydiethanol, propane-1,2-diol and butane-1,3-diol 701-276-1 - 2020 View substance registered dossier
Nisso Chemical Europe GmbH Berliner Allee 42 40212 Düsseldorf Germany Germany Active 4,4'-Sulfonylbisphenol polymer with 1,1'-oxybis[2-chloroethane] 427-620-8 - 2011; 2014 View substance registered dossier
Nisso Chemical Europe Berliner Allee 42 40212 Duesseldorf Germany Germany Active 4,4'-Sulfonylbisphenol polymer with 1,1'-oxybis[2-chloroethane] 427-620-8 - 2011; 2019 View substance registered dossier
[Confidential] - - - 4,4,19,19-tetraethoxy-3,20-dioxa-8,15-dithia-4,19-disiladocosaneand S-(6-{[3-(triethoxysilyl)propyl]thio}hexyl) ethanethioate 951-696-6 - - View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active 4,4,19,19-tetraethoxy-3,20-dioxa-8,15-dithia-4,19-disiladocosaneand S-(6-{[3-(triethoxysilyl)propyl]thio}hexyl) ethanethioate 951-696-6 - - View substance registered dossier
Yordas GmbH Äußere Nürnberger Str. 62, 91301 Forchheim Germany Germany Active 4,4’-isopropylidenediphenol, reaction products with 1-chloro-2,3-epoxypropane, mono, di and triesters with acrylic acid 948-054-2 - 2019; 2023 View substance registered dossier
ARKEMA FRANCE 420 rue d'Estienne d'Orves 92700 COLOMBES France France Active 4,5-di-tert-butyl-6-ethoxy-2,2-dimethyl-3,7-dioxa-4-aza-6-phosphanonan-1-oic acid 6-oxide 449-920-8 - 2010 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol 443-400-4 - 2016 View substance registered dossier
Piramal Healthcare UK Ltd Whalton Road NE61 3YA Morpeth Northumberland United Kingdom United Kingdom No longer Valid 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol 443-400-4 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol 443-400-4 - - View substance registered dossier
Fujifilm Imaging Colorants Limited Patricia Way Pysons Road Industrial Estate CT10 2LE Broadstairs Kent United Kingdom United Kingdom No longer Valid 4,5-dihydro-5-oxo-1-(4-sulfophenyl)-4-(4-{2-[1,2,7,8-tetrahydro-7-(4-nitro-2-sulfophenylhydrazono)-1,8-dioxo-3,6-disulfo-2-naphthylidene]hydrazino}-3-sulfophenylhydrazono)pyrazole-3-carboxylic acid, lithium sodium salt 445-080-1 - 2021 View substance registered dossier
Fujifilm Europe GmbH (OR1) Balcke-Dürr-Allee 6 40882 Ratingen Germany Germany Active 4,5-dihydro-5-oxo-1-(4-sulfophenyl)-4-(4-{2-[1,2,7,8-tetrahydro-7-(4-nitro-2-sulfophenylhydrazono)-1,8-dioxo-3,6-disulfo-2-naphthylidene]hydrazino}-3-sulfophenylhydrazono)pyrazole-3-carboxylic acid, lithium sodium salt 445-080-1 - 2021 View substance registered dossier
- - - - 4,6-bis[2-(4-hydroxyphenyl)isopropylidene]resorcinol 432-380-2 - - View substance registered dossier
Labcorp Development SA 151 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain Spain Active 4,6-bis[2-(4-hydroxyphenyl)isopropylidene]resorcinol 432-380-2 - 2011 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active 4,6-Dichloro-5-fluoropyrimidine 446-560-3 - 2010; 2022 View substance registered dossier
ELIX Polymers, S.L. Poligono Industrial s/n Ctra. de Vilaseca - La Pineda 43006 Tarragona Spain Spain Active 4,7-methanooctahydro-1H-indene-diyldimethyl bis(2-carboxybenzoate) 407-410-2 - 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 4,7-methanooctahydro-1H-indene-diyldimethyl bis(2-carboxybenzoate) 407-410-2 - - View substance registered dossier
INEOS Styrolution Köln GmbH Alte Str. 201 50769 Köln NRW Germany Germany Active 4,7-methanooctahydro-1H-indene-diyldimethyl bis(2-carboxybenzoate) 407-410-2 - 2011 View substance registered dossier
[Confidential] - - - 4-(1-((3-((2-(tert-butoxycarbonyl(methyl)amino)acetoxy)methyl)pyridin-2-yl)(methyl)carbamoyloxy)ethyl)-1-((2R,3S)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,5-difluorophenyl)-2-hydroxybutyl)-1H-1,2,4-triazol-4-ium sulphate 926-418-1 - - View substance registered dossier
URQUIMA S.A. AVDA. CAMÍ REIAL, 51 -57 08184 PALAU-SOLITÀ I PLEGAMANS CATALUNYA Spain Spain Active 4-(2-aminoethyl)indole, fumarate 947-445-5 - - View substance registered dossier
Thermofisher Scientific Cork Ltd. Currabinny P43 AY66 Carrigaline Co. Cork Ireland Ireland Active 4-(2-Hydroxyethyl)indolin-2-one 925-636-4 - 2021 View substance registered dossier
Aceto France SAS 3 Rue de Genève CS 50363 BP 50367 Lyon Cedex 06 France France Active 4-(3,4-dichlorophenyl)tetralin-1-one 406-300-1 - 2017 View substance registered dossier
MOEHS CATALANA Cesar Martinell i Brunet 12 A 08191 Rubi Barcelona Spain Spain Active 4-(3,4-dichlorophenyl)tetralin-1-one 406-300-1 - - View substance registered dossier
MOEHS BCN, S.L. C/ Zenc, 12 08755 Castellbisbal Barcelona Spain Spain Active 4-(3,4-dichlorophenyl)tetralin-1-one 406-300-1 - - View substance registered dossier
Alkaloida Chemical Company Zrt. Kabay Janos 29 H-4440 Tiszavasvari Hungary Hungary Active 4-(3,4-dichlorophenyl)tetralin-1-one 406-300-1 - - View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active 4-(3,4-dichlorophenyl)tetralin-1-one 406-300-1 - 2010 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active 4-(3,4-dichlorophenyl)tetralin-1-one 406-300-1 - - View substance registered dossier
- - - - 4-(4'-Trifluoromethylphenyl)benzaldehyde 473-430-3 - - View substance registered dossier
Fine and Performance Chemicals Ltd Skutterskelfe TS15 0JR Hutton Rudby North Yorkshire United Kingdom United Kingdom No longer Valid 4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butynyl)-α,α-dimethylbenzeneacetic acid 462-560-6 - 2021 View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active 4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butynyl)-α,α-dimethylbenzeneacetic acid 462-560-6 - 2013; 2015 View substance registered dossier
Amino Chemicals Ltd Industrial Estate, A61 MRS3000 Marsa Malta Malta Active 4-(4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-1-butynyl)-α,α-dimethylbenzeneacetic acid 462-560-6 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(4-Brom-5-ethyl-tetrahydropyran-2-yl)-phenol 919-822-4 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(4-Brom-5-propyl-tetrahydropyran-2-yl)-phenol 917-991-9 - - View substance registered dossier
All'Chem rue Marceau 03108 MONTLUCON CEDEX France France Active 4-(4-chloro-3-nitro-phenyl)-3-methyl-4-oxo-butanoic acid 918-019-6 - - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active 4-(4-chlorophenyl)-1-imidazol-1-ylbutan-2-ol 925-590-5 - - View substance registered dossier
- - - - 4-(4-hydroxyphenyl)cyclohexanone 423-920-8 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(4-trans-propylcylohexyl)phenol 440-740-5 - 2009; 2010; 2013; 2017; 2019 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(4-trans-vinyl-[1,1'-bicyclohexyl]-4'-trans-yl)-1,2-difluorobenzene 430-860-6 - 2019 View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa-Attiki Greece Greece Active 4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)-N-(2-ethyl-3-oxo-1,2-oxazolidin-4-yl)-2-methylbenzamide 954-921-6 - 2023 View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa-Attiki Greece Greece Active 4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl)-N-(2-ethyl-3-oxo-1,2-oxazolidin-4-yl)-2-methylbenzamide 954-921-6 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active 4-(5-(5-[1-(4-carboxyphenyl)hexahydro-2,4,6-trioxopyrimidin-5-ylidene]penta-1,3-dienyl)-1,2,3,4-tetrahydro-6-hydroxy-2,4-dioxopyrimidin-1-yl)benzoic acid-triethylamine salt 426-900-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - No longer Valid 4-(5-ethoxyheptyl)perhydropentalen-2-one 419-880-6 - 2022 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(5-Ethyl-tetrahydropyran-2-yl)-phenol 921-114-5 - 2020 View substance registered dossier
Piramal Healthcare UK Ltd Whalton Road NE61 3YA Morpeth Northumberland United Kingdom United Kingdom No longer Valid 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide 448-010-8 - 2021 View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide 448-010-8 - 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide 448-010-8 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(5-Propyl-tetrahydropyran-2-yl)-phenol 919-949-5 - 2021 View substance registered dossier
Eli Lilly Kinsale Limited Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland Ireland Active 4-(6-(3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)-6-(2-hydroxy-2-methylpropoxy)pyrazolo[1,5-a]pyridine-3-carbonitrile bis sulphate 951-814-6 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester) 425-880-7 - - View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active 4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester) 425-880-7 - 2019 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - No longer Valid 4-(6-acryloyloxyhexyloxy)benzoic acid (4-(trans-4-propylcyclohexyl)phenyl ester) 425-880-7 - 2022 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(Difluoro-(3,4,5-trifluoro-phenoxy)-methyl)-3,5-difluoro-benzaldehyde 942-738-4 - 2018; 2022 View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active 4-(nitromethyl)-1-(2-phenylethyl)piperidin-4-ol;hydrochloride 928-867-9 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-(trans-4-Propylcyclohexyl)-1-bromobenzene 485-340-1 - 2018; 2019 View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active 4-(trans-4-Propylcyclohexyl)-1-bromobenzene 485-340-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - No longer Valid 4-(trans-4-propylcyclohexyl)phenyl acetic acid 435-100-7 - 2022 View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company Little Island County NA Cork Ireland Ireland Active 4-({6-AMINO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE 458-850-7 - 2018 View substance registered dossier
TOYO INK EUROPE SPECIALTY CHEMICALS Boulevard Dambourney 76350 Oissel France France Active 4-[(4,6-bis{[3-(diethylamino)propyl]amino}-heteromonocycle-2-yl)amino]-N-[2-(4,5,6,7-tetrachloro-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)quinolin-8-yl]benzenesulfonamide - - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-[(4-(aminoiminomethyl)phenyl)amino]-4-oxobutanoic acid hydrochloride 430-340-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active 4-[(4-Fluorophenylimino)methyl]phenol 438-950-7 - - View substance registered dossier
Krka, d. d., Novo mesto Smarjeska cesta 6 SI-8501 Novo mesto Slovenia Slovenia Active 4-[(4-Fluorophenylimino)methyl]phenol 438-950-7 - - View substance registered dossier
Rolic Technologies B.V. Luchthavenweg 10 5657 EB Eindhoven Netherlands Netherlands Active 4-[(4-{[4-({5-[2-(acryloyloxy) ethoxy]-5-oxoalkanoyl}oxy) benzoyl]oxy}-2-methylaroxy)carbonyl] aryl 2-(acryloyloxy) ethyl alkandioate - - - View substance registered dossier
Janssen Pharmaceutical Science Unlimited Company Little Island County NA Cork Ireland Ireland Active 4-[(6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile 928-806-6 - - View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 4-[({(3R,3aR,6S,6aR)-6-[(4-{[4-({[4-(acryloyloxy)butoxy]carbonyl}oxy)benzoyl]oxy}benzoyl)oxy]hexahydrofuro[3,2-b]furan-3-yl}oxy)carbonyl]phenyl 4-({[4-(acryloyloxy)butoxy]carbonyl}oxy)benzoate 431-360-0 - 2011 View substance registered dossier
- - - - 4-[2-((6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-ylsulfanyl)thiazole-4-yl]-1-methyl-pyridiniumchloride monohydrochloride 447-990-4 - - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active 4-[2-((6R,7R)-7-amino-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-ylsulfanyl)thiazole-4-yl]-1-methyl-pyridiniumchloride monohydrochloride 447-990-4 - 2019 View substance registered dossier
Covestro NV Haven 507 Scheldelaan 420 2040 Antwerpen Belgium Belgium Active 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol, reaction product with diphenyl carbonate 926-571-4 - 2020 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active 4-[2-(Cyclopropylmethoxy)ethyl]phenol 440-910-9 - - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active 4-[2-(Cyclopropylmethoxy)ethyl]phenol 440-910-9 - 2017 View substance registered dossier
FINORGA - MOURENX avenue du lac 64150 MOURENX France France Active 4-[2-(Cyclopropylmethoxy)ethyl]phenol 440-910-9 - - View substance registered dossier
Agfa-Gevaert N.V. Septestraat 27 2640 Mortsel Belgium Belgium Active 4-[2-[(E)-2-[(3E)-2-chloro-3-[(2E)-2-[1,1-dimethyl-3-(4-sulfobutyl)benzo[e]indol-2-ylidene]ethylidene]inden-1-yl]vinyl]-1,1-dimethyl-benzo[e]indol-3-ium-3-yl]butane-1-sulfonate 942-705-4 - - View substance registered dossier
Schering-Plough (Ireland) Company Avondale Co Wicklow Avondale Co. Wicklow Ireland Ireland Cease Manufacture 4-[4-[4-[(3R, 5R)[5-(2,4-difluorophenyl) tetrahydro-5-(1H-1,2,4-triazol-1-yl-methyl)-furan-3-yl]methyloxy]phenyl]-1-piperazinyl]phenyl-2-[(1S,2S)(1-ethyl-2-phenylmethoxypropyl)]-2,4-dihydro-3Htriazol-3-one 938-153-9 - 2022 View substance registered dossier
MSD International GmbH (Ballydine Branch) Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active 4-[4-[4-[(3R, 5R)[5-(2,4-difluorophenyl) tetrahydro-5-(1H-1,2,4-triazol-1-yl-methyl)-furan-3-yl]methyloxy]phenyl]-1-piperazinyl]phenyl-2-[(1S,2S)(1-ethyl-2-phenylmethoxypropyl)]-2,4-dihydro-3Htriazol-3-one 938-153-9 - 2015; 2017 View substance registered dossier
- - - - 4-[bis(2-tert-butyl-4-hydroxy-6-methylphenyl)methyl]phenyl 6-diazo-5-oxo-5,6-dihydronaphthalene-1-sulfonate 451-040-4 - - View substance registered dossier
Covance Clinical Development SA 024 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 - 5 Planta 28050 Madrid Spain Spain Active 4-[bis(phenylsubstituted)substituted]phthalic acid - - 2020 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-[difluoro(3,4,5-trifluorophenoxy)methyl]-2',3,5-trifluoro-4''-pentyl-1,1':4',1''-terphenyl 935-977-0 - 2019 View substance registered dossier
ICROM S.r.l Via delle arti, 33 20863 Concorezzo Italy Italy Active 4-acetilammino-N-((1-etil-2pirrolidinil)metil) -5 etilsulfonil-2-metossi benzamide 925-003-2 - - View substance registered dossier
- - - - 4-acetyloxy-5β,20-epoxy-1,2α,4,7β,10β,13α-hexahydroxy-9-oxotax-11-en-2-yl benzoate 418-680-6 - - View substance registered dossier
Upjohn Manufacturing Ireland Unlimited Little Island T45 F627 Co. Cork Ireland Ireland Active 4-amino-1-Methyl-3-n-propyl-5-pyrazolecarboxamide hydrochloride 938-723-7 - 2019; 2021 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 51373 Leverkusen Germany Germany Active 4-Amino-2,3-dichlorophenol 464-070-8 - 2010 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 4-Amino-2,3-dichlorophenol 464-070-8 - 2011; 2021 View substance registered dossier
FARMAK, a.s. Na vlcinci 16/3 779 00 Olomouc Czech Republic Czech Republic Active 4-Amino-5-chloro-2,1,3-benzothiodiazole 457-490-8 - 2009; 2015 View substance registered dossier
- - - - 4-amino-5-ethyl-1-(2-methoxyethyl)-1H-Pyrazole-3-carboxamide 438-910-9 - - View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active 4-azidobutan-1-amine; (7,7-dimethyl-3-oxo-4-bicyclo[2.2.1]heptanyl)methanesulfonic acid 943-084-2 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-bromo-2,3',4',5'-tetrafluoro-1,1'-biphenyl 936-926-5 - - View substance registered dossier
Nufarm GmbH & Co.KG OR St.-Peter-Str.25 4021 Linz Austria Austria Active 4-butoxy-2,2,6,6-tetramethyl-1-piperidinyloxy 482-430-2 - 2014; 2016; 2021 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-Butoxy-2,3-difluor-4'-methyl-1,1'-biphenyl 938-422-0 - - View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa-Attiki Greece Greece Active 4-chloro-6-methoxypyrimidine 435-030-7 - 2014; 2015; 2020; 2022 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-chloromethyl-4''-ethyl-2'-fluoro-[1,1':4',1''-terphenyl] 936-119-8 - 2018; 2022 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-cis-ethyl-4'-trans-propyl-[1,1'-bicyclohexyl] 935-545-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-CPH 428-130-7 - - View substance registered dossier
Sasol Germany GmbH Anckelmannsplatz 1 D-20537 Hamburg Germany Germany Active 4-Cyclohexan-1-ol, dodecyl-, branched 938-702-2 - 2021 View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-ethoxy-2,3-difluoro-4'-(trans-4-propylcyclohexyl)-1,1'-biphenyl 921-136-5 - 2022 View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active 4-ethoxy-2,6-di(nonyl)-1,3-dioxane 920-431-6 - 2021 View substance registered dossier
Huntsman (Europe) BV - OR1 Everslaan 45 B-3078 Everberg Belgium Belgium Active 4-ethyl-1,3-dioxolan-2-one 403-780-4 - 2011 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active 4-ethyl-1,3-dioxolan-2-one 403-780-4 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active 4-ethyl-2-fluoro-4'-(2-(trans-4-propylcyclohexyl)ethyl)biphenyl 433-190-2 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active 4-Ethyl-3'-fluorobiphenyl 918-150-9 - 2021 View substance registered dossier
- - - - 4-Fluoro-3-hydroxybenzoic acid 434-190-5 - - View substance registered dossier
Fareva La Vallée 928 avenue Lavoisier ZI de Blavozy 43700 Saint Germain Laprade Auvergne France France Active 4-Fluoro-3-hydroxybenzoic acid 434-190-5 - - View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 4-fluoro-N-(propan-2-yl)aniline 448-100-7 - 2010; 2022 View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active 4-fluoro-N-(propan-2-yl)aniline 448-100-7 - 2010; 2014; 2020; 2021 View substance registered dossier
ACETO GmbH Hans-Henny-Jahnn-Weg 53 22085 Hamburg Germany Germany Active 4-fluoro-N-(propan-2-yl)aniline 448-100-7 - - View substance registered dossier
[Confidential] - - - 4-fluoro-N-(propan-2-yl)aniline 448-100-7 - - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active 4-hydroxy-3-methyl-5-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]pentan-2-one 949-712-1 - - View substance registered dossier
DSM Nutritional Products GmbH - OR1 Emil-Barell-Str. 3 79639 Grenzach-Wyhlen Germany Germany Active 4-hydroxybutan-2-one + 3-(hydroxymethyl)but-3-en-2-one 908-868-0 - 2020 View substance registered dossier
ORGANICA Feinchemie GmbH Wolfen Ortsteil Wolfen Kunstseidestraße 5 06766 Bitterfeld-Wolfen Germany Germany Active 4-hydroxybutane-1-sulfonic acid 928-903-3 - - View substance registered dossier
- - - - 4-hydroxyphenyl 4-(allyloxy)benzoate 433-210-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - No longer Valid 4-hydroxyphenyl 4-(allyloxy)benzoate 433-210-1 - 2022 View substance registered dossier
- - - - 4-hydroxystyrene, 4-tbutoxy styrene and styrene copolymer 433-660-7 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active 4-hydroxystyrene, 4-tbutoxy styrene and styrene copolymer 433-660-7 - - View substance registered dossier
MITSUBISHI GAS CHEMICAL EUROPE GMBH Immermannstr.13 40210 Duesseldorf Germany Germany Active 4-Isobutylbenzaldehyde 464-400-0 - 2014 View substance registered dossier
MITSUBISHI GAS CHEMICAL EUROPE GMBH Immermannstr. 13 40210 Duesseldorf Germany Germany Active 4-Isobutylbenzaldehyde 464-400-0 - 2014 View substance registered dossier
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Cease Manufacture 4-Methoxy-5-(3-morpholin-4-yl-propoxy)-2-nitro-benzonitrile 936-067-6 - 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. - - No longer Valid 4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 403-040-0 - 2022 View substance registered dossier
Bristol Myers Squibb Srl Via del Murillo., km 2, 8 004013 Sermoneta Lazio Italy Italy Active 4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 403-040-0 - - View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active 4-methoxybenzyl 3-chloromethyl-5-oxo-6-phenylacetamido-(2H)5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 403-040-0 - - View substance registered dossier
CBW Chemie GmbH Bitterfeld-Wolfen Kühlturmstrasse 3 06803 Bitterfeld-Wolfen / OT Greppin Germany Germany Active 4-Methoxycarbonyl-2-methylthiophen-3-yl-ammonium hydrochloride 929-732-7 - 2013 View substance registered dossier
AllessaProduktion GmbH Alt-Fechenheim 34 60386 Frankfurt am Main Germany Germany Cease Manufacture 4-methoxycyclohexanone 480-410-8 - 2019 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active 4-methoxycyclohexanone 480-410-8 - 2008; 2011; 2017 View substance registered dossier
BASF SE Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany Germany Active 4-methoxycyclohexanone 480-410-8 - - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active 4-methoxycyclohexanone 480-410-8 - 2011; 2022 View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Cease Manufacture 4-Methyl-2-propylbenzimidazole-6-carboxylic acid 424-450-6 - 2015 View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active 4-Methyl-2-propylbenzimidazole-6-carboxylic acid 424-450-6 - - View substance registered dossier
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Cease Manufacture 4-Methyl-2-propylbenzimidazole-6-carboxylic acid 424-450-6 - 2019 View substance registered dossier
AGC Pharma Chemicals Europe, S.L.U. Camí de la Pomereda, 13 08380 Malgrat de Mar (Barcelona) Spain Spain Active 4-Methyl-2-propylbenzimidazole-6-carboxylic acid 424-450-6 - - View substance registered dossier
Lek Pharmaceuticals d.d. Verovskova 57 1526 Ljubljana Slovenia Slovenia Active 4-methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-amine hydrobromide 946-432-1 - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.