Registered substances

Data platform availability banner - registered substances

The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM.  More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.


 

DISSEMINATION
PLATFORM

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
(3-fluoro-4'-pentyl[1,1'-biphenyl]-4-yl)-boronic acid
936-618-0 - Active Full Joint ≥ 0 to < 10 tonnes 12-02-2019 View substance registered dossier
(3-methoxy-2-methylpropyl)benzene
430-150-6 - Active Full Joint ≥ 1 to < 10 tonnes 22-12-2016 View substance registered dossier
(3-methoxy-2-methylpropyl)benzene
430-150-6 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(3AS,4S,6AR)-4-METHOXYTETRAHYDROFURO[3,4- B]FURAN-2(3H)-ONE
443-930-6 - Active Full Joint ≥ 10 to < 100 tonnes 03-05-2018 View substance registered dossier
(3AS,4S,6AR)-4-METHOXYTETRAHYDROFURO[3,4- B]FURAN-2(3H)-ONE
443-930-6 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(3beta)-17-(3-pyridinyl)androsta-5,16-dien-3-yl acetate compound with (2R,3R)-tartaric acid and methanol (1 : 1 : 1.5)
931-336-4 - Cease Manufacture Intermediate Individual Cease manufacture 13-09-2012 View substance registered dossier
(3R)-2,3-dihydro-1,1,3-trimethyl-1H-Inden-4-amine-(2S,3S)-2,3-dihydroxybutanedioate
701-382-8 - Active Intermediate Joint Intermediate use only 09-04-2021 View substance registered dossier
(3R)-4[(4-Methoxyphenyl)methyl]-3-methylpiperazine-2-one
954-618-9 - Active Intermediate Individual Intermediate use only 21-03-2022 View substance registered dossier
(3R,4S,6R,7R,9R,11S,12R,13S,14R)-6-{[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy]-10-(hydroxyimino)-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one
918-279-0 - Active Intermediate Joint Intermediate use only 26-04-2017 View substance registered dossier
(3R,7aR)-3-tert-butyl-7a-{methoxy[(trimethylsilyl)oxy]methyl}dihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione
942-823-6 - Cease Manufacture Intermediate Individual Cease manufacture 03-11-2015 View substance registered dossier
(3RS,3aRS,6SR,7aSR)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone and (3RS,3aSR,6RS,7aRS)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone
429-980-1 - Active NONS Joint Tonnage data confidential 15-12-2008 View substance registered dossier
(3S)-3-{4-[8-(2,4-dichlorophenyl)-3-(methoxycarbonyl)-6,7-dihydro-5H-benzocyclohepten-9-yl]phenoxy}-1-(3-fluoropropyl)pyrrolidinium hydrogen oxalate
950-060-5 - Active Intermediate Joint Intermediate use only 15-01-2020 View substance registered dossier
(3S,3S’)-Dineopentyl 4,4’-disulfanediylbis(3-(benzyloxycarbonylamino)butane-1-sulfonate
954-955-1 - Active Intermediate Joint Intermediate use only 27-09-2021 View substance registered dossier
(3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-1-benzyl-4-(4-fluorophenyl)piperidine
929-011-7 - Active Intermediate Joint Intermediate use only 20-04-2018 View substance registered dossier
(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate
436-150-2 - Active Intermediate Joint Intermediate use only 16-05-2018 View substance registered dossier
(3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate
436-150-2 - Active Intermediate Joint Intermediate use only 12-07-2013 View substance registered dossier
(3S,5S,6R)-3-amino-6-methyl-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-2-one 4-methylbenzoate
939-788-4 - Active Intermediate Joint Intermediate use only 15-05-2023 View substance registered dossier
(3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol
450-320-3 - Active Full Joint ≥ 0 to < 10 tonnes 16-04-2018 View substance registered dossier
(3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol
450-320-3 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(4-(6-diethylamino-2-methylpyridin-3-yl)imino-4,5-dihydro-3-methyl-1-(4-methylphenyl)-1H-pyrazol-5-one
427-070-9 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(4-6) PEPTIDE
427-550-8 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(4-methoxybiphenyl-3-yl)hydrazine hydrochloride
924-885-6 - Active Intermediate Joint Intermediate use only 22-10-2012 View substance registered dossier
(4-Methoxyphenyl)diphenylsulfoniumnonaflate
435-570-3 - Active NONS Joint Tonnage data confidential 24-06-2009 View substance registered dossier
(4-nitrophenyl)methyl [6R,(6α,7β)]-[3-hydroxy-5,8-dioxo-7-(phenoxyacetylamino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate]
ENOL SULFOXIDE ESTER
411-820-7 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(4-vinylphenyl)methyl-2-[(1Z)-1-aza-3-methyl-2-(4-methylthiophenyl)-3-morpholin-4-ylbut-1-enyloxy]acetate
453-050-4 - Active NONS Individual Tonnage data confidential 04-02-2011 View substance registered dossier
(4aR*, 8aR*)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1)
700-867-1 - Active Full Joint ≥ 1 to < 10 tonnes 11-06-2020 View substance registered dossier
(4aR,5S,8R,8aS)-1,2,3,4,4a,5,8,8a-octahydro-1,4:5,8-dimethanonaphthalene
700-678-4 - Active Full Individual ≥ 100 to < 1 000 tonnes 05-05-2020 View substance registered dossier
(4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one
939-401-9 - Active Full Joint ≥ 100 to < 1 000 tonnes 09-05-2023 View substance registered dossier
(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;N,N-diethylethanamine
926-346-0 - Active Intermediate Joint Intermediate use only 10-11-2017 View substance registered dossier
(4R)-4-methyl-1,3-dioxolan-2-one
(R)-1,2-PROPYLENE CARBONATE
437-320-9 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one
433-160-9 - Active Full Joint ≥ 1 to < 10 tonnes 18-08-2020 View substance registered dossier
(4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one
433-160-9 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(4R,4aS,7aR,12bS)-4a,9-dihydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one hemi((2R,3R)-2,3-dihydroxysuccinate)
956-466-9 - Active Intermediate Joint Intermediate use only 07-10-2022 View substance registered dossier
(4S)-3-carbamoyl-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-1-ium (2S,3S)-2,3-bis(benzoyloxy)-3-carboxypropanoate
947-346-7 - Active Intermediate Individual Intermediate use only 03-01-2023 View substance registered dossier
(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12aoctahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1)
940-053-5 - Active Intermediate Joint Intermediate use only 19-01-2017 View substance registered dossier
(4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide p-toluenesulfonate
947-931-7 - Active Intermediate Individual Intermediate use only 24-05-2018 View substance registered dossier
(4S,4aS,5aS,6S,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide di(4-chlorobenzenesulfonic acid)
925-915-0 - Active Intermediate Individual Intermediate use only 24-05-2018 View substance registered dossier
(4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid
HYDROXYECTOIN
442-870-8 - Cease Manufacture NONS Joint Cease manufacture 10-11-2008 View substance registered dossier
(4S,6S)-5,6-dihydro-4-[ethylamin-N-(2-nitrobenzenesulfonic)]-6-methyl-4H-thieno(2,3-b)thiopyran-7,7-dioxide
947-800-4 - Active Intermediate Joint Intermediate use only 21-06-2018 View substance registered dossier
(4S,7S,12bR)-7-amino-1,2,3,4,6,7,8,12b-octahydro-6-oxobenzo(c)pyrido(1,2-a)azepin-4-carbonic acid
MDL 28,690
443-440-2 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(5-chloro-2-methoxyphenyl)boronic acid
923-256-3 - Active Intermediate Individual Intermediate use only 27-04-2018 View substance registered dossier
(5E)-9-(dichloromethylidene)-N-hydroxy-2,3,4,6,7,8-hexahydro-1,4-methanonaphthalen-5(1H)-imine
700-700-2 - Active Intermediate Joint Intermediate use only 30-09-2022 View substance registered dossier
(5Z)-5-(2-methylpropylidene)imidazolidine-2,4-dione
700-726-4 - Active Intermediate Joint Intermediate use only 02-02-2022 View substance registered dossier
(6a,8xi,11b,14xi,16a)-6,9-difluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4- dien-21-yl benzoate
938-716-9 - No longer Valid Intermediate Individual No longer valid 04-02-2013 View substance registered dossier
(6R)-6-Dimethylamino-4,4-diphenyl-heptan-3-one; compound with 2-(toluene-4-sulfonylamino)-pentanedioic acid
921-925-4 - Active Intermediate Joint Intermediate use only 14-02-2022 View substance registered dossier
(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)
939-998-6 - Cease Manufacture Intermediate Joint Cease manufacture 24-11-2014 View substance registered dossier
(6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3)
939-998-6 - Active Intermediate Individual Intermediate use only 18-12-2013 View substance registered dossier
(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid, 1-butylammonium salt
439-350-8 - Cease Manufacture NONS Individual Cease manufacture 22-12-2010 View substance registered dossier
(6R,7R,14S)-17-cyano-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethano-17-normorphine
921-415-1 - Active Intermediate Individual Intermediate use only 01-09-2016 View substance registered dossier
(6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethanomorphine
918-453-6 - Active Intermediate Individual Intermediate use only 31-08-2016 View substance registered dossier
(6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-O-methyl-6,14-ethano-17-normorphine
917-585-1 - Active Intermediate Individual Intermediate use only 01-09-2016 View substance registered dossier
(6S)-2,6-dimethyloct-2-ene-8,8-diyl diacetate
949-377-1 - Active Intermediate Joint Intermediate use only 10-05-2019 View substance registered dossier
(6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide
431-140-4 - Active Intermediate Joint Intermediate use only 13-11-2017 View substance registered dossier
(6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide
431-140-4 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(6S,7S)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
435-680-1 - Cease Manufacture Full Individual Cease manufacture 17-05-2018 View substance registered dossier
(6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid
434-320-0 - Cease Manufacture NONS Joint Cease manufacture 15-11-2012 View substance registered dossier
(6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid
434-320-0 - Active Intermediate Joint Intermediate use only 08-10-2021 View substance registered dossier
(6Z)-6-(hydroxyimino)-5,6-dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1H,4H)-dione
695-945-4 - Active Intermediate Joint Intermediate use only 23-06-2022 View substance registered dossier
(7-methoxynaphthalen-1-yl)acetonitrile
461-670-1 - Active Full Individual ≥ 1 to < 10 tonnes 08-06-2010 View substance registered dossier
(7-methoxynaphthalen-1-yl)acetonitrile
461-670-1 - Active Intermediate Joint Intermediate use only 14-12-2021 View substance registered dossier
(7-methoxynaphthalen-1-yl)acetonitrile
461-670-1 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate and (7S,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6, 7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
943-624-7 - Active Intermediate Joint Intermediate use only 01-03-2022 View substance registered dossier
(7S,8R,9S,13S,14S,17S)-7-(9-chlorononyl)-3,17-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-6-one
955-019-5 - Active Intermediate Joint Intermediate use only 22-10-2021 View substance registered dossier
(8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione - 2,3,5,6-tetrachlorobenzene-1,4-diol (1:1)
926-987-6 - Active Intermediate Joint Intermediate use only 13-12-2021 View substance registered dossier
(8Z)-16-{[(2R,4S,5S)-6-[(acetyloxy)methyl]-3-{[(2S,4S,5S)-6-[(acetyloxy)methyl]-3,4,5-trihydroxyoxan-2-yl]oxy}-4,5-dihydroxyoxan-2-yl]oxy}heptadec-8-enoic acid; [(1S,4S,5S,8R,17Z,27S,31R)-28-[(acetyloxy)methyl]-4,5,30,31-tetrahydroxy-10-methyl-25-oxo-2,7,9,26,29-pentaoxatricyclo[25.2.2.0³,⁸]hentriacont-17-en-6-yl]methyl acetate
941-809-7 - Active Full Joint ≥ 10 to < 100 tonnes 18-05-2022 View substance registered dossier
(alpha-cyanobenzyl)malonic acid diethyl ester
922-463-6 - Active Intermediate Joint Intermediate use only 17-02-2017 View substance registered dossier
(aminoalkyl) hydrogen thiosulfate
- - Active Full Joint ≥ 1 to < 10 tonnes 05-01-2021 View substance registered dossier
(Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate
442-520-4 - Cease Manufacture NONS Individual Cease manufacture 10-11-2008 View substance registered dossier
(Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate
442-520-4 - Active Full Joint ≥ 1 tonnes 12-02-2020 View substance registered dossier
(C14-C30-alkyl)phenyl-3-tolyliodonium trifluoromethansulfonate
DOW CORNING(R) 2-7103 CATALYST
424-410-8 - No longer Valid NONS Individual No longer valid 10-11-2008 View substance registered dossier
(C14/C16/C18) n-alkyl (of non animal origin)benzyl dimethyl ammonium chloride compound with bentonite
TIXOGEL VZ-V
436-020-5 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(C16 or C18-n-alkyl)(C16 or C18-n-alkyl)ammonium 2-((C16 or C18-n-alkyl)(C16 or C18-n-alkyl)carbamoyl)benzenesulfonate
OA 8523
402-460-1 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(cis)-4-[2-[2-((1S,2S,5S)-6,6-dimethylnorpinan-2-yl)ethoxy]ethyl]morpholine
700-519-9 - Active Intermediate Joint Intermediate use only 13-01-2020 View substance registered dossier
(D)-2-BROM-3-PHENYLPROPIONSÄURE-ETHYLENDIAMINSALZ
447-890-0 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(D)-p-hydroxyphenylglycine-2-hydroxyethylester, hydrochloride
433-310-3 - Active NONS Joint Tonnage data confidential 04-02-2011 View substance registered dossier
(Dimethoxy(methyl)silyl)methyl 2-methacrylate
479-600-3 - Active Full Joint ≥ 1 tonnes 02-12-2016 View substance registered dossier
(E)- 1-(4-Methylsubstitutedphenyl-3-(3,5-dimethylaryl)propenone
- - Active Intermediate Joint Intermediate use only 21-09-2021 View substance registered dossier
(E)-(5,6-dihydro-1,4,2-dioxazin-3-yl)(2-hydroxyphenyl)methanone O-methyloxime
456-110-8 - Active Intermediate Joint Intermediate use only 06-04-2022 View substance registered dossier
(E)-1-(4-methylthiophenyl)-3-(3,5-dimethyl-4-tertbutyloxycarbonyldimethylmethylhydroxyphenyl)prop-2-en-1-one
- - Active Intermediate Joint Intermediate use only 21-09-2021 View substance registered dossier
(E)-2-((4-(ethyl(2-hydroxyethyl)amino)phenyl)diazenyl)-6-methoxy-3-methylbenzo[d]thiazol-3-ium trichlorozincate
944-280-0 - Active Full Joint ≥ 10 to < 100 tonnes 18-03-2020 View substance registered dossier
(E)-2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-ylmethylene)-5,6-dimethoxy-indan-1-one hydrochloride
940-983-1 - Active Intermediate Individual Intermediate use only 03-12-2014 View substance registered dossier
(E)-4-Dimethylamino-but-2-enoic acid [4-(3-chloro-4-fluoro-phenyl-amino)-7-((S)-(tetrahydrofuran-3-yl)oxy)-quinazoline-6-yl]-amide
923-981-5 - Active Intermediate Joint Intermediate use only 17-02-2023 View substance registered dossier
(E)-4-Ethoxy-1,1,1-trifluoro-3-buten-2-one (stabilized with BHT)
475-900-3 - Active Intermediate Individual Intermediate use only 10-12-2019 View substance registered dossier
(E)-ethyl 4-(dimethylamino)but-2-enoate maleate
941-772-7 - Active Intermediate Joint Intermediate use only 02-06-2015 View substance registered dossier
(E)-Ethyl 4-oxo-but-2-enoate
438-470-8 - Active NONS Joint Tonnage data confidential 09-06-2022 View substance registered dossier
(E)-Ethyl 4-oxo-but-2-enoate
438-470-8 - Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(E)-N'-hydroxy-N-(4-hydroxypyrid-2-yl)formimidamide
952-647-1 - Active Intermediate Joint Intermediate use only 01-07-2020 View substance registered dossier
(E)-N- (3-Chloroallyl)-n-Methyl-N-9Naphtalin-1-YL-methyl-amine
449-170-1 - Active NONS Joint Tonnage data confidential 24-09-2010 View substance registered dossier
(E)-N- (3-Chloroallyl)-n-Methyl-N-9Naphtalin-1-YL-methyl-amine
449-170-1 - Active NONS Joint Tonnage data confidential 12-06-2017 View substance registered dossier
(E)-N-((dialkylamino)alkylene)-3,5-bis(polyfluoroalkyl)benzamide
- - Active Intermediate Individual Intermediate use only 08-11-2016 View substance registered dossier
(ethyl-1,2-ethanediyl)]-2-[[[(2-hydroxyethyl)methylamino]acetyl]propyl]ω-(nonylphenoxy)poly[oxy(methyl-1,2-ethanediyl)
TFA-4713
418-960-8 - Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(imidazol-5-yl)ethyl-3-aminopropionamide dihydrochloride
CHLORHYDRATE DE CARCININE
415-470-6 - Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
(isopropyl (1s,3s)-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclobutane-1-carboxylate)
950-860-4 - Active Intermediate Joint Intermediate use only 04-05-2021 View substance registered dossier
(N-phenylcarbamimidoyl)ammonium carbonate hydrate
485-350-6 - Active Intermediate Individual Intermediate use only 19-08-2019 View substance registered dossier
(N-phenylcarbamimidoyl)ammonium carbonate hydrate
485-350-6 - Active Intermediate Individual Intermediate use only 21-12-2018 View substance registered dossier
(n-{(1s,3s)-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide hydrochloride)
952-248-2 - Active Intermediate Joint Intermediate use only 18-12-2020 View substance registered dossier
(NZ)-N-[1-(2,4-dichlorophenyl)-2-imidazol-1-ylethylidene]hydroxylamine
917-661-4 - Active Intermediate Joint Intermediate use only 14-02-2017 View substance registered dossier
(R)-1-(1H-benzo[d]imidazol-4-yl)propan-2-amine dihydrochloride
956-605-3 - Active Intermediate Joint Intermediate use only 27-10-2022 View substance registered dossier
(R)-1-(1H-indazol-4-yl)-N-(2,2,2-trifluoroethyl)propan-2-amine 10-camphorsulfonic acid salt
956-342-4 - Active Intermediate Joint Intermediate use only 01-09-2022 View substance registered dossier
(R)-1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline, compound with (S)-2-(6-methoxy-naphthalen-2-yl)-propionic acid
941-846-9 - Active Intermediate Individual Intermediate use only 17-03-2015 View substance registered dossier
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Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Merck KGaA Frankfurter Strasse 250 64293 Darmstadt Germany Germany Active (3-fluoro-4'-pentyl[1,1'-biphenyl]-4-yl)-boronic acid 936-618-0 - 2019 View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (3-methoxy-2-methylpropyl)benzene 430-150-6 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active (3-methoxy-2-methylpropyl)benzene 430-150-6 - - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (3AS,4S,6AR)-4-METHOXYTETRAHYDROFURO[3,4- B]FURAN-2(3H)-ONE 443-930-6 - 2010; 2018 View substance registered dossier
DSM Pharma Chemicals Venlo B.V. Grubbenvorsterweg 8 Postbox 81 5900 AB Venlo Netherlands Netherlands Active (3AS,4S,6AR)-4-METHOXYTETRAHYDROFURO[3,4- B]FURAN-2(3H)-ONE 443-930-6 - - View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Cease Manufacture (3beta)-17-(3-pyridinyl)androsta-5,16-dien-3-yl acetate compound with (2R,3R)-tartaric acid and methanol (1 : 1 : 1.5) 931-336-4 - 2019 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active (3R)-2,3-dihydro-1,1,3-trimethyl-1H-Inden-4-amine-(2S,3S)-2,3-dihydroxybutanedioate 701-382-8 - - View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active (3R)-4[(4-Methoxyphenyl)methyl]-3-methylpiperazine-2-one 954-618-9 - 2022 View substance registered dossier
Ercros SA Avenida Diagonal 593-595 08014 Barcelona Spain Spain Active (3R,4S,6R,7R,9R,11S,12R,13S,14R)-6-{[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl)oxy]-10-(hydroxyimino)-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecan-2-one 918-279-0 - - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Cease Manufacture (3R,7aR)-3-tert-butyl-7a-{methoxy[(trimethylsilyl)oxy]methyl}dihydro-1H-pyrrolo[1,2-c][1,3]oxazole-1,5(6H)-dione 942-823-6 - 2019 View substance registered dossier
- - - - (3RS,3aRS,6SR,7aSR)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone and (3RS,3aSR,6RS,7aRS)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone 429-980-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (3RS,3aRS,6SR,7aSR)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone and (3RS,3aSR,6RS,7aRS)-hexahydro-3,6-dimethyl-2(3H)-benzofuranone 429-980-1 - - View substance registered dossier
sanofi chimie 82 avenue Raspail 94250 Gentilly France France Active (3S)-3-{4-[8-(2,4-dichlorophenyl)-3-(methoxycarbonyl)-6,7-dihydro-5H-benzocyclohepten-9-yl]phenoxy}-1-(3-fluoropropyl)pyrrolidinium hydrogen oxalate 950-060-5 - - View substance registered dossier
ORGAPHARM Rue du Moulin de la Canne 45300 PITHIVIERS France France Active (3S,3S’)-Dineopentyl 4,4’-disulfanediylbis(3-(benzyloxycarbonylamino)butane-1-sulfonate 954-955-1 - - View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (3S,4R)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-1-benzyl-4-(4-fluorophenyl)piperidine 929-011-7 - - View substance registered dossier
MINAKEM Beuvry Production SAS 145, Chemin des Lilas 59310 Beuvry-la-Forêt France France Active (3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate 436-150-2 - - View substance registered dossier
MSD International GmbH Ballydine - Kilsheelan 0 Clonmel Ireland Ireland Active (3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate 436-150-2 - 2011; 2015 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate 436-150-2 - - View substance registered dossier
[Confidential] - - - (3S,5R)-4-chloro-[5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)furan-3-yl]methylbenzenesulfonate 436-150-2 - - View substance registered dossier
AbbVie Srl S.R. 148 Pontina Km 52 snc 04011 Campoverde di Aprilia (LT) Italy Italy Active (3S,5S,6R)-3-amino-6-methyl-5-phenyl-1-(2,2,2-trifluoroethyl)piperidin-2-one 4-methylbenzoate 939-788-4 - - View substance registered dossier
TAKASAGO TEPL-OR(1) 12 rue Torricelli 75017 Paris France France Active (3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol 450-320-3 - 2018 View substance registered dossier
- - - - (3S,6E)- 3,7,11-trimethyldodeca-6,10-dien-1-ol 450-320-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (4-(6-diethylamino-2-methylpyridin-3-yl)imino-4,5-dihydro-3-methyl-1-(4-methylphenyl)-1H-pyrazol-5-one 427-070-9 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Belgian competent national authority. - - Active (4-6) PEPTIDE 427-550-8 - - View substance registered dossier
Synthesia, a.s. Semtín103 53002 Pardubice Czech Republic Czech Republic Active (4-methoxybiphenyl-3-yl)hydrazine hydrochloride 924-885-6 - - View substance registered dossier
- - - - (4-Methoxyphenyl)diphenylsulfoniumnonaflate 435-570-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (4-Methoxyphenyl)diphenylsulfoniumnonaflate 435-570-3 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (4-nitrophenyl)methyl [6R,(6α,7β)]-[3-hydroxy-5,8-dioxo-7-(phenoxyacetylamino)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate] 411-820-7 - - View substance registered dossier
FujiFilm Manufacturing Europe BV Oudenstaart 1 5047 TK Tilburg Netherlands Netherlands Active (4-vinylphenyl)methyl-2-[(1Z)-1-aza-3-methyl-2-(4-methylthiophenyl)-3-morpholin-4-ylbut-1-enyloxy]acetate 453-050-4 - 2011 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (4aR*, 8aR*)-1-bromo-4a,5,9,10,11,12-hexahydro-3-methoxy-6H-benzofuro[3a,3,2-ef] [2]benzazepin-6-one hydrochloride (1:1) 700-867-1 - 2020 View substance registered dossier
Labcorp Development SA 163 Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 -5 Planta 28050 Madrid Spain Spain Active (4aR,5S,8R,8aS)-1,2,3,4,4a,5,8,8a-octahydro-1,4:5,8-dimethanonaphthalene 700-678-4 - 2019; 2020 View substance registered dossier
Solenis Netherlands B.V. Pesetastraat 62 2991 XT Barendrecht Netherlands Netherlands Active (4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one 939-401-9 - 2022; 2023 View substance registered dossier
Solenis Belgium B.V.B.A. Industrieweg 15 3583 Beringen Belgium Belgium Cease Manufacture (4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one 939-401-9 - 2016 View substance registered dossier
Mare S.p.A. Via Verdi No. 3 20002 Ossona Fraz. Asmonte Italy Italy Active (4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one 939-401-9 - 2020 View substance registered dossier
Red Orchid Consulting Oy Ltd Viherkallionkuja 3 I 59 02710 Espoo Finland Finland Active (4E)-4-(C13-C17)alkylidene-3-(C12-C16)alkyloxetan-2-one 939-401-9 - 2022 View substance registered dossier
DIPHARMA FRANCIS srl Bissone, 5 20021 Baranzate Milano Italy Italy Active (4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid;N,N-diethylethanamine 926-346-0 - - View substance registered dossier
Sterling Pharma Solutions Ltd Dudley NE23 7QG Cramlington Northumberland United Kingdom United Kingdom No longer Valid (4R)-4-methyl-1,3-dioxolan-2-one 437-320-9 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (4R)-4-methyl-1,3-dioxolan-2-one 437-320-9 - - View substance registered dossier
Visolis, B.V. Urmonderbaan 22 6167 RD Geleen Netherlands Netherlands Active (4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one 433-160-9 - - View substance registered dossier
- - - - (4R)-Tetrahydro-4-hydroxy-4-methyl-2H-Pyran-2-one 433-160-9 - - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (4R,4aS,7aR,12bS)-4a,9-dihydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one hemi((2R,3R)-2,3-dihydroxysuccinate) 956-466-9 - - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active (4S)-3-carbamoyl-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-1-ium (2S,3S)-2,3-bis(benzoyloxy)-3-carboxypropanoate 947-346-7 - 2020; 2021; 2023 View substance registered dossier
Hovione FarmaCiencia SA Sete Casas 2674-506 Loures Portugal Portugal Active (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12aoctahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1) 940-053-5 - 2017 View substance registered dossier
Hovione Limited Loughbeg not available Ringaskiddy County Cork Ireland Ireland Active (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12aoctahydrotetracene-2-carboxamide 4-methylbenzenesulfonate (1:1) 940-053-5 - 2017 View substance registered dossier
Cipan - Companhia Industrial Produtora de Antibióticos Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal Portugal Active (4S,4aS,5aR,12aS)-4-(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide p-toluenesulfonate 947-931-7 - - View substance registered dossier
Cipan - Companhia Industrial Produtora de Antibióticos Rua da Estação, 42 Vala do Carregado 2600-726 Castanheira do Ribatejo Lisboa Portugal Portugal Active (4S,4aS,5aS,6S,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide di(4-chlorobenzenesulfonic acid) 925-915-0 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - No longer Valid (4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid 442-870-8 - 2022 View substance registered dossier
- - - - (4S,5S)-5-hydroxy-2-methyl-3,4,5,6-tetrahydropyrimidine-4-carboxylic acid 442-870-8 - - View substance registered dossier
DUKE CHEM, S.A. Avgda. Mare de Déu de Montserrat, 93 - 99 Pol. Ind. Sant Pere Molanta 08799 Olèrdola Barcelona Spain Spain Active (4S,6S)-5,6-dihydro-4-[ethylamin-N-(2-nitrobenzenesulfonic)]-6-methyl-4H-thieno(2,3-b)thiopyran-7,7-dioxide 947-800-4 - - View substance registered dossier
Sanofi S.R.L. Viale Luigi Bodio n. 37/b 20158 Milano Italy Italy Active (4S,7S,12bR)-7-amino-1,2,3,4,6,7,8,12b-octahydro-6-oxobenzo(c)pyrido(1,2-a)azepin-4-carbonic acid 443-440-2 - - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (5-chloro-2-methoxyphenyl)boronic acid 923-256-3 - - View substance registered dossier
[Confidential] - - - (5E)-9-(dichloromethylidene)-N-hydroxy-2,3,4,6,7,8-hexahydro-1,4-methanonaphthalen-5(1H)-imine 700-700-2 - - View substance registered dossier
Syngenta Hellas Single Member S.A.C.I. Anthousas Avenue 153 49 Anthousa-Attiki Greece Greece Active (5E)-9-(dichloromethylidene)-N-hydroxy-2,3,4,6,7,8-hexahydro-1,4-methanonaphthalen-5(1H)-imine 700-700-2 - 2014; 2018; 2020; 2022 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany No longer Valid (5Z)-5-(2-methylpropylidene)imidazolidine-2,4-dione 700-726-4 - 2017 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (5Z)-5-(2-methylpropylidene)imidazolidine-2,4-dione 700-726-4 - 2022 View substance registered dossier
Glaxo Operations UK Glaxo Wellcome House Berkeley Avenue UB6 0NN Greenford Middlesex United Kingdom United Kingdom No longer Valid (6a,8xi,11b,14xi,16a)-6,9-difluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4- dien-21-yl benzoate 938-716-9 - 2021 View substance registered dossier
EUROAPI Germany GmbH Brüningstraße 50 65926 Frankfurt am Main Germany Germany Active (6R)-6-Dimethylamino-4,4-diphenyl-heptan-3-one; compound with 2-(toluene-4-sulfonylamino)-pentanedioic acid 921-925-4 - 2022 View substance registered dossier
Corden Pharma Latina S.p.A. Via Murillo, 7 IT04013 Sermoneta (LT) Lazio Italy Italy Cease Manufacture (6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3) 939-998-6 - 2017 View substance registered dossier
ACS DOBFAR S.p.A Viale Addetta 4/12 20067 Tribiano Milano Italy Italy Active (6R,7R)-3-[(5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl]-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate trifluoroacetate (1:3) 939-998-6 - - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid, 1-butylammonium salt 439-350-8 - 2021 View substance registered dossier
Teva Czech Industries s.r.o. Ostravska 29/305 74770 Opava - Komarov Czech Republic Czech Republic Active (6R,7R,14S)-17-cyano-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethano-17-normorphine 921-415-1 - - View substance registered dossier
Teva Czech Industries s.r.o. Ostravska 29/305 74770 Opava - Komarov Czech Republic Czech Republic Active (6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-3,6-O-dimethyl-6,14-ethanomorphine 918-453-6 - - View substance registered dossier
Teva Czech Industries s.r.o. Ostravska 29/305 74770 Opava - Komarov Czech Republic Czech Republic Active (6R,7R,14S)-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-O-methyl-6,14-ethano-17-normorphine 917-585-1 - - View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (6S)-2,6-dimethyloct-2-ene-8,8-diyl diacetate 949-377-1 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide 431-140-4 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (6S)-6-methyl-5,6-Dihydro-4H-thieno[2,3-b]thiopyran4-one-7,7-dioxide 431-140-4 - - View substance registered dossier
Sandoz GmbH Biochemiestr. 10 6250 Kundl Austria Austria Cease Manufacture (6S,7S)-7-Amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 435-680-1 - 2021 View substance registered dossier
[Confidential] - - - (6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid 434-320-0 - - View substance registered dossier
HH Compliance Ltd Rubicon Building CIT Campus T12 Y275 Bishopstown Cork Ireland Ireland Cease Manufacture (6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid 434-320-0 - 2023 View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active (6S,9R,10S,11S,13S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid 434-320-0 - - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (6Z)-6-(hydroxyimino)-5,6-dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1H,4H)-dione 695-945-4 - - View substance registered dossier
EGIS Pharmaceuticals PLC Keresztúri út 30-38 H-1106 Budapest Hungary Hungary Active (7-methoxynaphthalen-1-yl)acetonitrile 461-670-1 - - View substance registered dossier
LABORATORIOS SERVIER S.L. RIO JARAMA 59 45007 TOLEDO Spain Spain Active (7-methoxynaphthalen-1-yl)acetonitrile 461-670-1 - 2011; 2018 View substance registered dossier
EUROAPI Hungary Ltd. Tó utca 1-5. 1045 Budapest Hungary Hungary Active (7-methoxynaphthalen-1-yl)acetonitrile 461-670-1 - 2021 View substance registered dossier
ORIL INDUSTRIE 13 rue Auguste Desgenétais 76210 BOLBEC France France Active (7-methoxynaphthalen-1-yl)acetonitrile 461-670-1 - - View substance registered dossier
Minakem High Potent s.a. Rue Fonds Jean Pâques 8 1435 Mont-Saint-Guibert Belgium Belgium Active (7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate and (7S,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6, 7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate 943-624-7 - - View substance registered dossier
STERLING CHEMICAL MALTA LTD. HF51, Hal-Far Industrial Estate BBG 3000 Birżebbuġa Malta Malta Active (7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate and (7S,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6, 7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate 943-624-7 - - View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Active (7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate and (7S,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6, 7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate 943-624-7 - 2018 View substance registered dossier
AstraZeneca Alderley Park AZ SHE Chemical Registration SK10 4TF Macclesfield Cheshire United Kingdom United Kingdom No longer Valid (7R,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6,7,8,9,10,11,12,13,14,15,16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate and (7S,13S,17S)-13-methyl-3-oxo-7-(9-((4,4,5,5,5-pentafluoropentyl)thio)nonyl)-2,3,6, 7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate 943-624-7 - 2021 View substance registered dossier
Industriale Chimica s.r.l. via E.H. Grieg, 13 21074 Saronno (VA) Italy Italy Active (7S,8R,9S,13S,14S,17S)-7-(9-chlorononyl)-3,17-dihydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-6-one 955-019-5 - - View substance registered dossier
Gedeon Richter Plc. Gyomroi ut 19-21 1103 Budapest Hungary Hungary Active (8R,9S,10R,13S,14S,17R)-10,13-Dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione - 2,3,5,6-tetrachlorobenzene-1,4-diol (1:1) 926-987-6 - 2021 View substance registered dossier
Evonik Operations GmbH Rellinghauser Straße 1-11 45128 Essen Germany Germany Active (8Z)-16-{[(2R,4S,5S)-6-[(acetyloxy)methyl]-3-{[(2S,4S,5S)-6-[(acetyloxy)methyl]-3,4,5-trihydroxyoxan-2-yl]oxy}-4,5-dihydroxyoxan-2-yl]oxy}heptadec-8-enoic acid; [(1S,4S,5S,8R,17Z,27S,31R)-28-[(acetyloxy)methyl]-4,5,30,31-tetrahydroxy-10-methyl-25-oxo-2,7,9,26,29-pentaoxatricyclo[25.2.2.0³,⁸]hentriacont-17-en-6-yl]methyl acetate 941-809-7 - 2022 View substance registered dossier
Evonik Fermas s.r.o. Slovenská Ľupča 938 976 13 Slovenská Ľupča Slovakia Slovakia Active (8Z)-16-{[(2R,4S,5S)-6-[(acetyloxy)methyl]-3-{[(2S,4S,5S)-6-[(acetyloxy)methyl]-3,4,5-trihydroxyoxan-2-yl]oxy}-4,5-dihydroxyoxan-2-yl]oxy}heptadec-8-enoic acid; [(1S,4S,5S,8R,17Z,27S,31R)-28-[(acetyloxy)methyl]-4,5,30,31-tetrahydroxy-10-methyl-25-oxo-2,7,9,26,29-pentaoxatricyclo[25.2.2.0³,⁸]hentriacont-17-en-6-yl]methyl acetate 941-809-7 - 2016; 2019; 2021; 2022 View substance registered dossier
JSC "Olainfarm" Rupnicu str. 5 LV-2114 Olaine Latvia Latvia Active (alpha-cyanobenzyl)malonic acid diethyl ester 922-463-6 - - View substance registered dossier
RSI ChemRep Europe Ltd (S001) 27-30 Merchants Quay Merchants House 8 Dublin Ireland Ireland Active (aminoalkyl) hydrogen thiosulfate - - 2017; 2021 View substance registered dossier
Archroma Italy, S.r.l. - OR Via Manzoni 37 20030 Palazzolo Milanese Italy Italy Cease Manufacture (Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate 442-520-4 - 2017 View substance registered dossier
ARCHROMA IBÉRICA, S.L. ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain Spain Active (Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate 442-520-4 - 2020 View substance registered dossier
Archroma Ibérica, S.L. - OR ZAL-Prat c/Cal Coracero, 46-56 08820 El Prat de Llobregat Spain Spain Cease Manufacture (Benzyloxycarbonyl)methyl 4-(1-Butyl-5-cyano-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridylazo)-benzoate 442-520-4 - 2020 View substance registered dossier
- - - - (C14-C30-alkyl)phenyl-3-tolyliodonium trifluoromethansulfonate 424-410-8 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (C14/C16/C18) n-alkyl (of non animal origin)benzyl dimethyl ammonium chloride compound with bentonite 436-020-5 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (C16 or C18-n-alkyl)(C16 or C18-n-alkyl)ammonium 2-((C16 or C18-n-alkyl)(C16 or C18-n-alkyl)carbamoyl)benzenesulfonate 402-460-1 - - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (C16 or C18-n-alkyl)(C16 or C18-n-alkyl)ammonium 2-((C16 or C18-n-alkyl)(C16 or C18-n-alkyl)carbamoyl)benzenesulfonate 402-460-1 - - View substance registered dossier
OLON Spa Strada Rivoltana Km 6/7 20053 RODANO Milano Italy Italy Active (cis)-4-[2-[2-((1S,2S,5S)-6,6-dimethylnorpinan-2-yl)ethoxy]ethyl]morpholine 700-519-9 - 2017 View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active (cis)-4-[2-[2-((1S,2S,5S)-6,6-dimethylnorpinan-2-yl)ethoxy]ethyl]morpholine 700-519-9 - - View substance registered dossier
- - - - (D)-2-BROM-3-PHENYLPROPIONSÄURE-ETHYLENDIAMINSALZ 447-890-0 - - View substance registered dossier
Deretil S.A.U. Villaricos, s/n 04618 Cuevas del Almanzora Almeria Spain Spain Cease Manufacture (D)-p-hydroxyphenylglycine-2-hydroxyethylester, hydrochloride 433-310-3 - 2023 View substance registered dossier
Bristol Myers Squibb Srl Via del Murillo., km 2, 8 004013 Sermoneta Lazio Italy Italy Active (D)-p-hydroxyphenylglycine-2-hydroxyethylester, hydrochloride 433-310-3 - - View substance registered dossier
ABCR Laboratorios, S.L. Poligono Industrial de Vilapouca 36555 Forcarei Galicia Spain Spain Active (Dimethoxy(methyl)silyl)methyl 2-methacrylate 479-600-3 - - View substance registered dossier
Wacker Chemie AG Hanns-Seidel-Platz 4 81737 Muenchen Germany Germany Active (Dimethoxy(methyl)silyl)methyl 2-methacrylate 479-600-3 - 2016 View substance registered dossier
[Confidential] - - - (E)- 1-(4-Methylsubstitutedphenyl-3-(3,5-dimethylaryl)propenone - - - View substance registered dossier
Bayer AG Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany Germany Active (E)-(5,6-dihydro-1,4,2-dioxazin-3-yl)(2-hydroxyphenyl)methanone O-methyloxime 456-110-8 - 2017; 2022 View substance registered dossier
Saltigo GmbH HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany Germany Active (E)-(5,6-dihydro-1,4,2-dioxazin-3-yl)(2-hydroxyphenyl)methanone O-methyloxime 456-110-8 - 2011; 2014; 2015 View substance registered dossier
[Confidential] - - - (E)-1-(4-methylthiophenyl)-3-(3,5-dimethyl-4-tertbutyloxycarbonyldimethylmethylhydroxyphenyl)prop-2-en-1-one - - - View substance registered dossier
Only representative (No publishable name) - - Active (E)-2-((4-(ethyl(2-hydroxyethyl)amino)phenyl)diazenyl)-6-methoxy-3-methylbenzo[d]thiazol-3-ium trichlorozincate 944-280-0 - - View substance registered dossier
Reach & Colours Trade Kft Levente u. 14/a 2161 Csomád Hungary Hungary Active (E)-2-((4-(ethyl(2-hydroxyethyl)amino)phenyl)diazenyl)-6-methoxy-3-methylbenzo[d]thiazol-3-ium trichlorozincate 944-280-0 - - View substance registered dossier
REACH&Colours Kft Petofi Sandor utca 11 I Em. 4 1052 Budapest Hungary Hungary Active (E)-2-((4-(ethyl(2-hydroxyethyl)amino)phenyl)diazenyl)-6-methoxy-3-methylbenzo[d]thiazol-3-ium trichlorozincate 944-280-0 - 2020 View substance registered dossier
Pliva Hrvatska doo Prilaz baruna Filipovića 25 10000 Zagreb Croatia Croatia Active (E)-2-(1-Benzyl-1,2,3,6-tetrahydro-pyridin-4-ylmethylene)-5,6-dimethoxy-indan-1-one hydrochloride 940-983-1 - - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (E)-4-Dimethylamino-but-2-enoic acid [4-(3-chloro-4-fluoro-phenyl-amino)-7-((S)-(tetrahydrofuran-3-yl)oxy)-quinazoline-6-yl]-amide 923-981-5 - 2015; 2023 View substance registered dossier
Solvay Fluor GmbH Hans-Boeckler-Allee 20 30173 HANNOVER Germany Germany Active (E)-4-Ethoxy-1,1,1-trifluoro-3-buten-2-one (stabilized with BHT) 475-900-3 - 2010; 2014; 2019 View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active (E)-ethyl 4-(dimethylamino)but-2-enoate maleate 941-772-7 - 2015 View substance registered dossier
WeylChem Lamotte S.A.S Rue du Flottage B.P. 1 60350 Trosly Breuil France France Active (E)-Ethyl 4-oxo-but-2-enoate 438-470-8 - 2021; 2022 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active (E)-Ethyl 4-oxo-but-2-enoate 438-470-8 - - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active (E)-N'-hydroxy-N-(4-hydroxypyrid-2-yl)formimidamide 952-647-1 - - View substance registered dossier
Novartis Integrated Services Limited Ringaskiddy P43 FR63 Ringaskiddy Co. Cork Ireland Ireland Active (E)-N- (3-Chloroallyl)-n-Methyl-N-9Naphtalin-1-YL-methyl-amine 449-170-1 - 2010 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (E)-N- (3-Chloroallyl)-n-Methyl-N-9Naphtalin-1-YL-methyl-amine 449-170-1 - - View substance registered dossier
Derivados Químicos S.A. Camino de Pliego, 150 30820 Alcantarilla Murcia Spain Spain Active (E)-N- (3-Chloroallyl)-n-Methyl-N-9Naphtalin-1-YL-methyl-amine 449-170-1 - 2017 View substance registered dossier
FINORGA SAS 497 route de Givors 38670 CHASSE SUR RHONE France France Active (E)-N-((dialkylamino)alkylene)-3,5-bis(polyfluoroalkyl)benzamide - - 2016 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (ethyl-1,2-ethanediyl)]-2-[[[(2-hydroxyethyl)methylamino]acetyl]propyl]ω-(nonylphenoxy)poly[oxy(methyl-1,2-ethanediyl) 418-960-8 - - View substance registered dossier
- - - - (imidazol-5-yl)ethyl-3-aminopropionamide dihydrochloride 415-470-6 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (isopropyl (1s,3s)-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclobutane-1-carboxylate) 950-860-4 - 2020 View substance registered dossier
Curia France SAS ZI de Laville 47240 BON-ENCONTRE France France Active (isopropyl (1s,3s)-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclobutane-1-carboxylate) 950-860-4 - - View substance registered dossier
Alzchem Trostberg GmbH Dr.-Albert-Frank-Straße 32 83308 Trostberg Bayern Germany Germany Active (N-phenylcarbamimidoyl)ammonium carbonate hydrate 485-350-6 - 2009; 2019 View substance registered dossier
[Confidential] - - - (N-phenylcarbamimidoyl)ammonium carbonate hydrate 485-350-6 - - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X336 Ringaskiddy Cork Ireland Ireland Active (n-{(1s,3s)-3-[methyl(7h-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide hydrochloride) 952-248-2 - 2020 View substance registered dossier
ERREGIERRE SPA Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy Italy Active (NZ)-N-[1-(2,4-dichlorophenyl)-2-imidazol-1-ylethylidene]hydroxylamine 917-661-4 - - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (R)-1-(1H-benzo[d]imidazol-4-yl)propan-2-amine dihydrochloride 956-605-3 - - View substance registered dossier
Cambrex Karlskoga AB Bjorkborns Industriomrade 69185 Karlskoga Sweden Sweden Active (R)-1-(1H-indazol-4-yl)-N-(2,2,2-trifluoroethyl)propan-2-amine 10-camphorsulfonic acid salt 956-342-4 - - View substance registered dossier
RECORDATI SPA Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy Italy Active (R)-1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline, compound with (S)-2-(6-methoxy-naphthalen-2-yl)-propionic acid 941-846-9 - - View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.