Registered substances

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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM. More

Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration

Showing 18,351 - 18,400 of 26,865 results.

Name	EC / List no.	CAS no.	Registration Status	Registration type	Submission type	Total tonnage band	Last Updated	Details
Bottom residues resulting from dimethylformamide regenaration and separation of piperylene and benzene in the synthesis of isoprene from dehyrdogenation of isopentane	700-785-6	-	Active	Intermediate	Individual	Intermediate use only	05-12-2012	View substance registered dossier
Bottom residues resulting from the synthesis of dimethyldioxane and the synthesis of isoprene from dimethyldioxane and trimethylcarbinol	700-775-1	-	Active	Intermediate	Individual	Intermediate use only	05-12-2012	View substance registered dossier
Bottom residues resulting from the synthesis of isoprene and isoamylene by dehydrogenation of isopentane	700-774-6	-	Active	Intermediate	Individual	Intermediate use only	02-11-2015	View substance registered dossier
Bottom residues resulting from the synthesis of propene by propane dehydrogenation	701-004-1	-	Active	Intermediate	Joint	Intermediate use only	22-07-2016	View substance registered dossier
Bottom residues resulting from the synthesis of propylene oxide and styrene from epoxidation of propylene with ethylbenzene hydroperoxide	700-801-1	-	Active	Intermediate	Individual	Intermediate use only	05-12-2012	View substance registered dossier
Branched and linear mono-C20,22,24 and di-C10-13 alkyl benzenesulfonicacids and petroleum sulfonic acids	701-455-4	-	Active	Intermediate	Joint	Intermediate use only	08-07-2022	View substance registered dossier
Bromhexine	222-684-1	3572-43-8	Active	Intermediate	Joint	Intermediate use only	16-03-2018	View substance registered dossier
Bromine	231-778-1	7726-95-6	Active	Intermediate	Joint	Intermediate use only	28-03-2018	View substance registered dossier
Bromo(1-methylethyl)magnesium	213-056-8	920-39-8	Active	Intermediate	Joint	Intermediate use only	18-12-2019	View substance registered dossier
bromo(4-fluorophenyl)magnesium	627-087-3	352-13-6	Active	Intermediate	Joint	Intermediate use only	06-06-2016	View substance registered dossier
Bromo(diphenyl)methane	212-279-8	776-74-9	Active	Intermediate	Joint	Intermediate use only	20-09-2018	View substance registered dossier
Bromo(fluoro)methane	481-800-0	-	Active	Intermediate	Joint	Intermediate use only	21-11-2022	View substance registered dossier
Bromo[4-(dimethylamino)phenyl]magnesium	615-983-7	7353-91-5	Active	Intermediate	Joint	Intermediate use only	22-09-2021	View substance registered dossier
Bromoacetic acid	201-175-8	79-08-3	Active	Intermediate	Joint	Intermediate use only	22-05-2019	View substance registered dossier
Bromoacetyl bromide	209-923-5	598-21-0	Active	Intermediate	Joint	Intermediate use only	10-05-2022	View substance registered dossier
Bromobenzene	203-623-8	108-86-1	Active	Intermediate	Joint	Intermediate use only	12-08-2022	View substance registered dossier
Bromochloromethane	200-826-3	74-97-5	Active	Intermediate	Joint	Intermediate use only	06-04-2018	View substance registered dossier
Bromochloromethane	200-826-3	74-97-5	Active	Intermediate	Individual	Intermediate use only	19-12-2014	View substance registered dossier
Bromocyclohexane	203-622-2	108-85-0	Active	Intermediate	Joint	Intermediate use only	06-06-2018	View substance registered dossier
Bromocyclopentane	205-294-6	137-43-9	Active	Intermediate	Joint	Intermediate use only	12-02-2019	View substance registered dossier
Bromocyclopentylmagnesium	251-420-8	33240-34-5	Active	Intermediate	Joint	Intermediate use only	06-06-2016	View substance registered dossier
Bromoethane	200-825-8	74-96-4	Active	Intermediate	Joint	Intermediate use only	17-05-2019	View substance registered dossier
Bromoethylene	209-800-6	593-60-2	Active	Intermediate	Joint	Intermediate use only	07-07-2022	View substance registered dossier
Bromoethylmagnesium	213-127-3	925-90-6	Active	Intermediate	Joint	Intermediate use only	07-09-2022	View substance registered dossier
Bromomethane	200-813-2	74-83-9	Active	Intermediate	Joint	Intermediate use only	22-04-2021	View substance registered dossier
Bromomethyl 2,5-dimethoxyphenyl ketone	214-873-2	1204-21-3	Active	Intermediate	Joint	Intermediate use only	15-03-2021	View substance registered dossier
Bromomethylcyclopropane	230-331-8	7051-34-5	Active	Intermediate	Joint	Intermediate use only	06-03-2019	View substance registered dossier
Bromophenylmagnesium	202-867-2	100-58-3	Active	Intermediate	Individual	Intermediate use only	24-06-2020	View substance registered dossier
Bromotrichloromethane	200-886-0	75-62-7	Active	Intermediate	Joint	Intermediate use only	24-03-2022	View substance registered dossier
Bromotrifluoromethane	200-887-6	75-63-8	Active	Intermediate	Joint	Intermediate use only	20-07-2018	View substance registered dossier
Bromotrimethylsilane	220-672-0	2857-97-8	Active	Intermediate	Joint	Intermediate use only	23-11-2022	View substance registered dossier
Buprenorphine	257-950-6	52485-79-7	Active	Intermediate	Joint	Intermediate use only	05-04-2023	View substance registered dossier
Buprenorphine	257-950-6	52485-79-7	No longer Valid	Intermediate	Individual	No longer valid	11-01-2016	View substance registered dossier
Buspirone	253-072-2	36505-84-7	Active	Intermediate	Joint	Intermediate use only	01-09-2020	View substance registered dossier
But-3-en-3-olide	211-617-1	674-82-8	Active	Intermediate	Joint	Intermediate use only	03-08-2021	View substance registered dossier
But-3-enenitrile	203-701-1	109-75-1	Active	Intermediate	Joint	Intermediate use only	22-12-2022	View substance registered dossier
But-3-yn-1-ol	213-161-9	927-74-2	Active	Intermediate	Joint	Intermediate use only	24-05-2016	View substance registered dossier
But-3-yn-2-ol	217-978-1	2028-63-9	Active	Intermediate	Joint	Intermediate use only	09-06-2016	View substance registered dossier
Butamirate	242-005-2	18109-80-3	Active	Intermediate	Joint	Intermediate use only	28-03-2018	View substance registered dossier
butan-1,4-diyl 4-carboxy-4-{[(1-(diethoxyphosphinyl)-2,2-dimethylpropyl)(1,1-dimethylethyl)amino]oxy}-2,2-dimethylbutanoate.	685-497-8	850348-10-6	Active	Intermediate	Individual	Intermediate use only	22-01-2014	View substance registered dossier
Butan-1-ol	200-751-6	71-36-3	Active	Intermediate	Individual	Intermediate use only	04-03-2015	View substance registered dossier
Butane-1,2-diol	209-527-2	584-03-2	Cease Manufacture	Intermediate	Joint	Cease manufacture	13-11-2019	View substance registered dossier
Butane-1,4-disulfonic acid	700-472-4	27665-39-0	Active	Intermediate	Individual	Intermediate use only	01-02-2011	View substance registered dossier
Butane-1-thiol	203-705-3	109-79-5	Active	Intermediate	Joint	Intermediate use only	06-04-2022	View substance registered dossier
Butanedioic acid, 2,3-bis(benzoyloxy)-, (2R,3R)-, compd. with (2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanone (1:1)	617-656-4	850222-41-2	Active	Intermediate	Joint	Intermediate use only	19-11-2018	View substance registered dossier
Butanedioic acid, 2,3-bis(benzoyloxy)-, (2R,3R)-, compd. with (2S)-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide (1:2)	817-148-4	27262-39-1	Active	Intermediate	Joint	Intermediate use only	30-06-2020	View substance registered dossier
Butanedioic acid, 2,3-bis(benzoyloxy)-, (2R,3R)-, compd. with (2S,3aS,6aS)-phenylmethyl octahydrocyclopenta[b]pyrrole-2-carboxylate (1:1) (9CI)	600-479-1	103728-95-6	Active	Intermediate	Joint	Intermediate use only	10-02-2022	View substance registered dossier
Butanedione	207-069-8	431-03-8	Active	Intermediate	Individual	Intermediate use only	29-05-2018	View substance registered dossier
Butanedione	207-069-8	431-03-8	Active	Intermediate	Joint	Intermediate use only	01-05-2020	View substance registered dossier
Butanone	201-159-0	78-93-3	No longer Valid	Intermediate	Individual	No longer valid	29-10-2012	View substance registered dossier

Showing 18,351 - 18,400 of 26,865 results.

Registrant/Supplier	Address	Country	Registration Status	Name	EC / List no.	CAS no.	Last update year	Details
BD&I_37	rue Omer Lepreux, 92 1081 bruxelles Belgium Belgium	Belgium	Active	Bottom residues resulting from dimethylformamide regenaration and separation of piperylene and benzene in the synthesis of isoprene from dehyrdogenation of isopentane	700-785-6	-	2012	View substance registered dossier
Oy Nizhex Scandinavia Ltd	Wavulinintie 10 00210 HELSINKI Finland	Finland	Active	Bottom residues resulting from the synthesis of dimethyldioxane and the synthesis of isoprene from dimethyldioxane and trimethylcarbinol	700-775-1	-	2012	View substance registered dossier
Oy Nizhex Scandinavia Ltd	Wavulinintie 10 00210 HELSINKI Finland	Finland	Active	Bottom residues resulting from the synthesis of isoprene and isoamylene by dehydrogenation of isopentane	700-774-6	-	2012; 2015	View substance registered dossier
BASF Sonatrach Propanchem S.A.	Carretera Nacional 340, km 1.156 43006 Tarragona Spain	Spain	Active	Bottom residues resulting from the synthesis of propene by propane dehydrogenation	701-004-1	-	2016	View substance registered dossier
Oy Nizhex Scandinavia Ltd	Wavulinintie 10 00210 HELSINKI Finland	Finland	Active	Bottom residues resulting from the synthesis of propylene oxide and styrene from epoxidation of propylene with ethylbenzene hydroperoxide	700-801-1	-	2012	View substance registered dossier
Sonneborn Refined Products BV	Mainhavenweg 6 1043AL Amsterdam Netherlands	Netherlands	Active	Branched and linear mono-C20,22,24 and di-C10-13 alkyl benzenesulfonicacids and petroleum sulfonic acids	701-455-4	-	2011; 2018; 2020; 2022	View substance registered dossier
Chevron Oronite SA M/I	Le Corosa 1, rue Eugène et Armand Peugeot CS10022 92508 Rueil-Malmaison Cedex France	France	Active	Branched and linear mono-C20,22,24 and di-C10-13 alkyl benzenesulfonicacids and petroleum sulfonic acids	701-455-4	-	2012; 2020; 2022	View substance registered dossier
A.M.S.A. Anonima Materie Sintetiche e Affini S.p.A.	Viale del Ghisallo, 20 20151 Milano Italy	Italy	Active	Bromhexine	222-684-1	3572-43-8	-	View substance registered dossier
Arcerion GmbH	Gabrielenstr. 15 80636 München Germany	Germany	Active	Bromine	231-778-1	7726-95-6	-	View substance registered dossier
Albemarle Germany GmbH	Industriepark Höchst Gebäude G 879 65926 Frankfurt Germany	Germany	Active	Bromo(1-methylethyl)magnesium	213-056-8	920-39-8	-	View substance registered dossier
Albemarle Germany GmbH	Industriepark Höchst Gebäude G 879 65926 Frankfurt Germany	Germany	Active	bromo(4-fluorophenyl)magnesium	627-087-3	352-13-6	-	View substance registered dossier
Vynova PPC SAS	95 rue du Général de Gaulle BP 60090 68802 THANN CEDEX France	France	Active	Bromo(diphenyl)methane	212-279-8	776-74-9	-	View substance registered dossier
Chemosyntha BV	Stedestraat 51 B-8530 Harelbeke West Vlaanderen Belgium	Belgium	Active	Bromo(diphenyl)methane	212-279-8	776-74-9	-	View substance registered dossier
RECORDATI SPA	Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy	Italy	Active	Bromo(diphenyl)methane	212-279-8	776-74-9	-	View substance registered dossier
F-Select GmbH	Grosshesseloherstr. 18 81479 Munich Germany	Germany	Active	Bromo(fluoro)methane	481-800-0	-	-	View substance registered dossier
PCAS	21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France	France	Active	Bromo[4-(dimethylamino)phenyl]magnesium	615-983-7	7353-91-5	2021	View substance registered dossier
ALBEMARLE EUROPE SPRL	Parc Scientifique (Einstein) Rue du Bosquet 9 1348 LOUVAIN-LA-NEUVE Belgium	Belgium	Active	Bromoacetic acid	201-175-8	79-08-3	-	View substance registered dossier
B-Lands Consulting (811725-2)	5 Place Robert Schuman - BP 1516 38025 Grenoble France France	France	Active	Bromoacetic acid	201-175-8	79-08-3	-	View substance registered dossier
PALCHEM	Rue du Transvaal BP22 62143 ANGRES France	France	Active	Bromoacetic acid	201-175-8	79-08-3	-	View substance registered dossier
Vynova PPC SAS	95 rue du Général de Gaulle BP 60090 68802 THANN CEDEX France	France	Active	Bromoacetic acid	201-175-8	79-08-3	2019	View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a.	Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy	Italy	Active	Bromoacetyl bromide	209-923-5	598-21-0	-	View substance registered dossier
Patheon Austria GmbH & Co KG	St. Peterstrasse 25 A-4020 Linz Austria	Austria	Active	Bromoacetyl bromide	209-923-5	598-21-0	-	View substance registered dossier
B-Lands Consulting (811725-2)	5 Place Robert Schuman - BP 1516 38025 Grenoble France France	France	Active	Bromoacetyl bromide	209-923-5	598-21-0	-	View substance registered dossier
Contract Chemicals Ltd	Penrhyn Road Knowsley Business Park L34 9HY Prescot Merseyside United Kingdom	United Kingdom	No longer Valid	Bromoacetyl bromide	209-923-5	598-21-0	2021	View substance registered dossier
Evonik Operations GmbH	Rellinghauser Straße 1-11 45128 Essen Germany	Germany	Active	Bromoacetyl bromide	209-923-5	598-21-0	2022	View substance registered dossier
ACS DOBFAR S.p.A	Viale Addetta 4/12 20067 Tribiano Milano Italy	Italy	Active	Bromoacetyl bromide	209-923-5	598-21-0	-	View substance registered dossier
DIPHARMA FRANCIS srl	Bissone, 5 20021 Baranzate Milano Italy	Italy	Active	Bromobenzene	203-623-8	108-86-1	-	View substance registered dossier
ALBEMARLE EUROPE SPRL	Parc Scientifique (Einstein) Rue du Bosquet 9 1348 LOUVAIN-LA-NEUVE Belgium	Belgium	Active	Bromochloromethane	200-826-3	74-97-5	-	View substance registered dossier
ICL Europe Coöperatief U.A. (OR1)	Koningin Wilhelminaplein 30 Prinsenhof 1062 KR Amsterdam Netherlands	Netherlands	Active	Bromochloromethane	200-826-3	74-97-5	-	View substance registered dossier
Saltigo GmbH	HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany	Germany	Active	Bromochloromethane	200-826-3	74-97-5	-	View substance registered dossier
Laboratorios Miret, S.A.	Geminis 4 08228 Terrassa Barcelona Spain	Spain	Active	Bromochloromethane	200-826-3	74-97-5	-	View substance registered dossier
B-Lands Consulting (811725-2)	5 Place Robert Schuman - BP 1516 38025 Grenoble France France	France	Active	Bromocyclohexane	203-622-2	108-85-0	-	View substance registered dossier
Contract Chemicals Ltd	Penrhyn Road Knowsley Business Park L34 9HY Prescot Merseyside United Kingdom	United Kingdom	No longer Valid	Bromocyclohexane	203-622-2	108-85-0	2021	View substance registered dossier
Contract Chemicals Ltd	Penrhyn Road Knowsley Business Park L34 9HY Prescot Merseyside United Kingdom	United Kingdom	No longer Valid	Bromocyclopentane	205-294-6	137-43-9	2021	View substance registered dossier
Arran Chemical Company Ltd	Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland	Ireland	Active	Bromocyclopentane	205-294-6	137-43-9	-	View substance registered dossier
CU Chemie Uetikon GmbH	Raiffeisenstrasse 4 77933 Lahr Baden-Württemberg Germany	Germany	Active	Bromocyclopentane	205-294-6	137-43-9	2016	View substance registered dossier
Albemarle Germany GmbH	Industriepark Höchst Gebäude G 879 65926 Frankfurt Germany	Germany	Active	Bromocyclopentylmagnesium	251-420-8	33240-34-5	-	View substance registered dossier
ICL-IP Terneuzen B.V. (M)	Frankrijkweg 6, Havens/Docks 1205-45308 BJ 4538 BJ Terneuzen Netherlands	Netherlands	Active	Bromoethane	200-825-8	74-96-4	-	View substance registered dossier
CS Regulatory Ireland Ltd. in its legal capacity as Only Representative of LANXESS Corporation	Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland	Ireland	Active	Bromoethane	200-825-8	74-96-4	-	View substance registered dossier
REACH24H CONSULTING GROUP	Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland	Ireland	Active	Bromoethane	200-825-8	74-96-4	-	View substance registered dossier
Aceto France SAS	3 Rue de Genève CS 50363 BP 50367 Lyon Cedex 06 France	France	Active	Bromoethane	200-825-8	74-96-4	-	View substance registered dossier
Klaus F. Meyer GmbH	Leiblstraße 3 67136 Fussgoenheim Germany	Germany	Active	Bromoethane	200-825-8	74-96-4	-	View substance registered dossier
PROCOS SpA	via Matteotti 249 28062 Cameri Piemonte Italy	Italy	Active	Bromoethane	200-825-8	74-96-4	-	View substance registered dossier
ORGAPHARM	Rue du Moulin de la Canne 45300 PITHIVIERS France	France	Active	Bromoethane	200-825-8	74-96-4	-	View substance registered dossier
Vynova PPC SAS	95 rue du Général de Gaulle BP 60090 68802 THANN CEDEX France	France	Active	Bromoethane	200-825-8	74-96-4	2013; 2019	View substance registered dossier
Thomas Swan & Co. Ltd.	Rotary Way DH8 7ND Consett Co. Durham United Kingdom	United Kingdom	No longer Valid	Bromoethane	200-825-8	74-96-4	2021	View substance registered dossier
Chr. Olesen ChemPharm GmbH	Innungsstr. 3 21244 Buchholz Germany	Germany	Active	Bromoethane	200-825-8	74-96-4	-	View substance registered dossier
Biesterfeld Spezialchemie GmbH	Ferdinandstr. 41 20095 Hamburg Germany	Germany	Active	Bromoethane	200-825-8	74-96-4	-	View substance registered dossier
Gedeon Richter Plc.	Gyomroi ut 19-21 1103 Budapest Hungary	Hungary	Active	Bromoethane	200-825-8	74-96-4	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	Bromoethylene	209-800-6	593-60-2	2012; 2016; 2022	View substance registered dossier
Albemarle Germany GmbH	Industriepark Höchst Gebäude G 879 65926 Frankfurt Germany	Germany	Active	Bromoethylmagnesium	213-127-3	925-90-6	2016	View substance registered dossier
Vertellus Specialties Belgium NV	Havenlaan 86C Bus 204 1000 Brussels Belgium	Belgium	Active	Bromoethylmagnesium	213-127-3	925-90-6	-	View substance registered dossier
Chemische Fabrik Karl Bucher GmbH	An der Guenz 1 89367 Waldstetten Germany	Germany	Active	Bromoethylmagnesium	213-127-3	925-90-6	2019; 2020; 2022	View substance registered dossier
ORGAPHARM	Rue du Moulin de la Canne 45300 PITHIVIERS France	France	Active	Bromoethylmagnesium	213-127-3	925-90-6	2018	View substance registered dossier
Mebrom	Antwerpsesteenweg 45 2830 Willebroek Belgium	Belgium	Active	Bromomethane	200-813-2	74-83-9	2013; 2014	View substance registered dossier
ICL Europe Coöperatief U.A. (OR1)	Koningin Wilhelminaplein 30 Prinsenhof 1062 KR Amsterdam Netherlands	Netherlands	Active	Bromomethane	200-813-2	74-83-9	-	View substance registered dossier
Mebrom NV	INDUSTRIELAAN 9 9990 MALDEGEM Belgium	Belgium	Active	Bromomethane	200-813-2	74-83-9	-	View substance registered dossier
CHEMO BIOSYNTHESIS SRL	VIALE ISONZO, 8 20135 MILANO Italy	Italy	Active	Bromomethyl 2,5-dimethoxyphenyl ketone	214-873-2	1204-21-3	-	View substance registered dossier
MINAKEM Beuvry Production SAS	145, Chemin des Lilas 59310 Beuvry-la-Forêt France	France	Active	Bromomethylcyclopropane	230-331-8	7051-34-5	-	View substance registered dossier
Aceto France S.A.S	3 Rue de Genève 69451 Lyon Cedex 06 France	France	Active	Bromomethylcyclopropane	230-331-8	7051-34-5	2019	View substance registered dossier
PALCHEM	Rue du Transvaal BP22 62143 ANGRES France	France	Active	Bromomethylcyclopropane	230-331-8	7051-34-5	-	View substance registered dossier
M2I SALIN	112 bureaux de la colline 92213 St Cloud France	France	Active	Bromomethylcyclopropane	230-331-8	7051-34-5	-	View substance registered dossier
H. Lundbeck A/S	Ottiliavej 7-9 2500 Copenhagen Denmark	Denmark	Active	Bromophenylmagnesium	202-867-2	100-58-3	2020	View substance registered dossier
B-Lands Consulting (811725-2)	5 Place Robert Schuman - BP 1516 38025 Grenoble France France	France	Active	Bromotrichloromethane	200-886-0	75-62-7	-	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	Active	Bromotrichloromethane	200-886-0	75-62-7	-	View substance registered dossier
REACH24H CONSULTING GROUP	Suite 1E, Paramount Court, Corrig Road, Sandyford Dublin 18 Dublin Ireland	Ireland	Active	Bromotrifluoromethane	200-887-6	75-63-8	-	View substance registered dossier
ARKEMA FRANCE	420 rue d'Estienne d'Orves 92700 COLOMBES France	France	Active	Bromotrifluoromethane	200-887-6	75-63-8	2017	View substance registered dossier
[Confidential]	-	-	-	Bromotrifluoromethane	200-887-6	75-63-8	-	View substance registered dossier
Merck KGaA	Frankfurter Strasse 250 64293 Darmstadt Germany	Germany	Active	Bromotrimethylsilane	220-672-0	2857-97-8	-	View substance registered dossier
Chemische Fabrik Karl Bucher GmbH	An der Guenz 1 89367 Waldstetten Germany	Germany	Active	Bromotrimethylsilane	220-672-0	2857-97-8	2018; 2021; 2022	View substance registered dossier
Teva Czech Industries s.r.o.	Ostravska 29/305 74770 Opava - Komarov Czech Republic	Czech Republic	Active	Buprenorphine	257-950-6	52485-79-7	-	View substance registered dossier
Macfarlan Smith Limited	Wheatfield Road EH11 2QA Edinburgh United Kingdom	United Kingdom	No longer Valid	Buprenorphine	257-950-6	52485-79-7	2021	View substance registered dossier
Siegfried PharmaChemikalien Minden GmbH	Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany	Germany	Active	Buprenorphine	257-950-6	52485-79-7	-	View substance registered dossier
Indivior UK Ltd	Henry Boot Way HU4 7DY Hull United Kingdom	United Kingdom	No longer Valid	Buprenorphine	257-950-6	52485-79-7	2021	View substance registered dossier
Excella GmbH & Co. KG	Nuernberger Str. 12 90537 Feucht Germany	Germany	Active	Buspirone	253-072-2	36505-84-7	2020	View substance registered dossier
Fareva La Vallée	928 avenue Lavoisier ZI de Blavozy 43700 Saint Germain Laprade Auvergne France	France	Active	Buspirone	253-072-2	36505-84-7	-	View substance registered dossier
Mitsubishi_Chemical_Europe_GmbH	Schiessstraße 47 40549 Düsseldorf Germany	Germany	Active	But-3-en-3-olide	211-617-1	674-82-8	2021	View substance registered dossier
Heubach Colorants Germany GmbH	Brüningstrasse 50 65929 Frankfurt am Main Germany	Germany	Active	But-3-en-3-olide	211-617-1	674-82-8	2016	View substance registered dossier
Chemische Fabrik Karl Bucher GmbH	An der Guenz 1 89367 Waldstetten Germany	Germany	Active	But-3-enenitrile	203-701-1	109-75-1	2019; 2020; 2022	View substance registered dossier
DOW CHEMICAL COMPANY LTD	Diamond House, Lotus Park Kingsbury Crescent Middx UB7 0DQ Staines Middx United Kingdom	United Kingdom	No longer Valid	But-3-enenitrile	203-701-1	109-75-1	2021	View substance registered dossier
Amino Chemicals Ltd	Industrial Estate, A61 MRS3000 Marsa Malta	Malta	Active	But-3-yn-1-ol	213-161-9	927-74-2	-	View substance registered dossier
DIPHARMA FRANCIS srl	Bissone, 5 20021 Baranzate Milano Italy	Italy	Active	But-3-yn-1-ol	213-161-9	927-74-2	-	View substance registered dossier
Givaudan Iberica SA	Pla d'en Batlle s/n 08470 San Celoni Barcelona Spain	Spain	Active	But-3-yn-2-ol	217-978-1	2028-63-9	-	View substance registered dossier
OLON Spa	Strada Rivoltana Km 6/7 20053 RODANO Milano Italy	Italy	Active	Butamirate	242-005-2	18109-80-3	2017	View substance registered dossier
FARMAK, a.s.	Na vlcinci 16/3 779 00 Olomouc Czech Republic	Czech Republic	Active	Butamirate	242-005-2	18109-80-3	-	View substance registered dossier
ARKEMA FRANCE	420 rue d'Estienne d'Orves 92700 COLOMBES France	France	Active	butan-1,4-diyl 4-carboxy-4-{[(1-(diethoxyphosphinyl)-2,2-dimethylpropyl)(1,1-dimethylethyl)amino]oxy}-2,2-dimethylbutanoate.	685-497-8	850348-10-6	2014	View substance registered dossier
DEZA a.s.	Masarykova 753 75701 Valasske Mezirici Czech Republic	Czech Republic	Active	Butan-1-ol	200-751-6	71-36-3	-	View substance registered dossier
IVICT Europe GmbH	Kennedydamm 19 40476 Düsseldorf Germany	Germany	Cease Manufacture	Butane-1,2-diol	209-527-2	584-03-2	2022	View substance registered dossier
EURO-KEMICAL Srl	via SABBIONCELLI, SNC 24050 COVO (BG) Italy	Italy	Active	Butane-1,4-disulfonic acid	700-472-4	27665-39-0	-	View substance registered dossier
Saltigo GmbH	HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany	Germany	Active	Butane-1-thiol	203-705-3	109-79-5	-	View substance registered dossier
Chevron Phillips Chemicals International NV	Airport Plaza, Stockholm Building, Da Vincilaan 19 B-1831 DIEGEM Belgium	Belgium	Active	Butane-1-thiol	203-705-3	109-79-5	2019	View substance registered dossier
Chevron Phillips Chemicals International N.V. - OR CPC	Airport Plaza, Stockholm Building Da Vincilaan 19 1831 Diegem Belgium	Belgium	Active	Butane-1-thiol	203-705-3	109-79-5	-	View substance registered dossier
Gruenenthal GmbH	Zieglerstrasse 6 52078 Aachen Germany	Germany	Active	Butanedioic acid, 2,3-bis(benzoyloxy)-, (2R,3R)-, compd. with (2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanone (1:1)	617-656-4	850222-41-2	-	View substance registered dossier
Első Vegyi Industria ZRt.	Kartács utca 6. H-1139 BUDAPEST Hungary	Hungary	Active	Butanedioic acid, 2,3-bis(benzoyloxy)-, (2R,3R)-, compd. with (2S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanone (1:1)	617-656-4	850222-41-2	2018	View substance registered dossier
Huvepharma Italia s.r.l.	Via Roberto Lepetit, 142 12075 GARESSIO (CN) Italy	Italy	Active	Butanedioic acid, 2,3-bis(benzoyloxy)-, (2R,3R)-, compd. with (2S)-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide (1:2)	817-148-4	27262-39-1	-	View substance registered dossier
Edmond Pharma s.r.l.	Strada Statale dei Giovi, 131 20037 Paderno Dugnano (MI) Italy	Italy	Active	Butanedioic acid, 2,3-bis(benzoyloxy)-, (2R,3R)-, compd. with (2S)-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide (1:2)	817-148-4	27262-39-1	-	View substance registered dossier
EUROAPI Germany GmbH	Brüningstraße 50 65926 Frankfurt am Main Germany	Germany	Active	Butanedioic acid, 2,3-bis(benzoyloxy)-, (2R,3R)-, compd. with (2S,3aS,6aS)-phenylmethyl octahydrocyclopenta[b]pyrrole-2-carboxylate (1:1) (9CI)	600-479-1	103728-95-6	2022	View substance registered dossier
NC NATURE CHEMICALS Dr. Kruppa GmbH	Marienring 9 22043 Hamburg Germany	Germany	Active	Butanedione	207-069-8	431-03-8	-	View substance registered dossier
[Confidential]	-	-	-	Butanedione	207-069-8	431-03-8	-	View substance registered dossier
BASF SE	Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany	Germany	No longer Valid	Butanone	201-159-0	78-93-3	2019	View substance registered dossier

Showing 18,351 - 18,400 of 26,865 results.

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
Link to the full factsheet.

Chemical Property Data Search

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

RELATED INFORMATION

Welcome to the REACH Registered Substance Factsheets

Here you will find details from REACH registrations submitted to ECHA. Registrations under REACH can be submitted either jointly – where a group of legal entities pool their data – or individually. The set of details from each published joint or individual submission is presented as a row in the results table. For each row there is also an ‘eye’ icon leading to the detailed factsheet which contains the entire public dataset, following the IUCLID format.

Note that there can be more than one joint or individual submission for the same substance, thus there can be cases where one substance is covered by many REACH registered substance factsheets.

Note too, that as mentioned in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission.

Finally, please note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

All substances table

The “All substances” table gives an overview of all the REACH registered substance factsheets on file at ECHA. Since this covers all data ever submitted since the entry into force of the REACH Regulation, there are some substances which are no longer considered registered under REACH in the EU / EEA. These can be for example substances that were registered only in the UK; since Brexit they are no longer registered in the EU / EEA.

The following columns are presented in the “All substances” table:

Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
‘Eye’ icon linking to the full factsheet.

Searching

The search for REACH registered substance factsheets is divided into logically separated blocks of related search filters. Note that the search works so that if you provide filters in different blocks, then the results returned must match the filters in block 1 AND those in block 2 etc. Searches are conducted on all the public data included in all published REACH registrations.

Substance identity

In this block you can search by substance identifiers, under filters for Name, EC / List number, and CAS number. Full or partial identifiers can be used. And under the Name filter you can search by any substance name of any kind from any source. Other numerical identifiers such as Harmonised C&L Index number, or PIC CN code can also optionally be used.

Administrative data

In this block you can search by administrative information relating to REACH registered substance factsheets:

Registration type – picklist of Full, Intermediate, NONS
Registration status – picklist of Active, Cease Manufacture, No longer valid
Submission type – Individual or Joint
Country in which registered – picklist of current and former EU / EEA member states from which REACH registrations were received
First published date – the date when a REACH registration factsheet was first published
Last update date – the last date when any registrant / supplier submission contributing to a given REACH registration factsheet was submitted
Last update year – the year in which any registrant / supplier last made an update submission included in a given REACH registration factsheet
Registrant / supplier name – where available and not claimed confidential
Registration number – where available and not claimed confidential
Registrant address – where available and not claimed confidential

Substance data

In this block you can search by substance related data from REACH registered substance factsheets:

Tonnage band – picklist of Tonnage range, Tonnage Confidential, Intermediate use only
Selected total tonnage band range – available only if Tonnage range is selected, and allows to filter REACH registered substance factsheets within any selected min and max value
Substance has nanoform – picklist of Yes, No
PBT assessment outcome – picklist of all possible PBT assessment outcomes
CSA performed – picklist of Yes, No

Use and exposure

In this block you can search by elements relating to how use and exposure are encoded in REACH registrations.

Under the Life cycle option you can select one or more life cycle stages. The search results returned will include only factsheets containing uses reported under the selected life cycle stages.

Under the Category option there are modal popups for each of the use descriptor categories – Product, Sector of use, Process, Environmental release, and Article categories. In each of these are multi select picklists for all the related descriptor codes. The search results returned will include only factsheets containing uses which include the selected descriptor codes.

Note that the Life cycle and Category options work together, so that if a life cycle stage and Category options are both selected the search results will include factsheets containing specific uses in the selected life cycle stage, and where the use includes the selected descriptor codes.

With the search operator option you can select to refine how the search works. AND refines results and returns only those factsheets where ALL the search filter criteria are met. OR broadens the results and returns factsheets where ANY of the selected search filter criteria are met.

The factsheets

There is always a detailed factsheet per joint or individual submission, and it is generated based primarily on the IUCLID format.

The factsheet header begins with the identity of the substance in question, to which the factsheet is linked. The substance identity should always be aligned with that shown in the related substance Infocard. Note that since the Infocard refreshes daily, whereas the factsheet sometimes refreshes on a slower pace, sometimes the data may be out of alignment. In such cases it will always realign as quickly as possible.

The substance identification is enriched with the data provided in the relevant IUCLID section of the primary submitted dossier – either the joint submission lead, or the single individual submission.

In this section are also provided the type of substance, all other identifiers such as trade names, common names, other names etc, as well as all distinct submitted compositions for the substance.

Next is a page covering administrative type information from the data submitted, including:

Registration details, on the total tonnage band informed to ECHA, the registration type, first published and last updated dates, and whether a chemical safety assessment has been performed.

Registrant / supplier details, giving the identity and status of registrants / suppliers, except where the identity has been claimed confidential.

Registration numbers, giving again the identity and status of registration numbers, except where claimed confidential.

Contact persons responsible for the SDS, giving the non-confidential SDS contacts provided to ECHA.

The remainder of the factsheet faithfully follows the IUCLID structure, covering the C&L and PBT, Manufacture, use, and exposure, Physical and chemical properties, Environmental fate and pathways, Ecotoxicological information, Toxicological information, Analytical methods (if available), Guidance on safe use, Assessment reports, and Reference substances.