Registered substances

Registered substances

Registered substances

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REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation

Registered Substances Factsheets

Substances which have been registered and can be placed on the EEA market by those companies with a valid registration



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Details
(1R,4S)-6-tert-butoxy-4-(tert-butyldimethylsilyloxy)-6-oxo-1-(2-(thiophen-2-yl)acetamido)hexylboronic acid, (+)-pinanediol ester
812-137-0 1681053-97-3 Active Intermediate Joint Intermediate use only 02-05-2018 View substance registered dossier
(1R,5aR,10R,11aS)-1-acetyl-10-[4-(dimethylamino)phenyl]-5a-hydroxy-11a-methyl-3,3a,3b,4,5,6,8,9,10,11-decahydro-2H-spiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolan]-1-yl acetate
615-905-1 730962-28-4 Active Intermediate Joint Intermediate use only 19-06-2018 View substance registered dossier
(1R,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene
232-087-8 7785-70-8 Active Full Joint ≥ 10 to < 100 tonnes 18-12-2019 View substance registered dossier
(1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylic acid
944-682-6 - Active Intermediate Joint Intermediate use only 22-12-2017 View substance registered dossier
(1R,8S)-2,2,7,7-tetramethyltricyclo[6.2.1.0^{1,6}]undec-5-en-4-one
942-035-2 - Active Intermediate Individual Intermediate use only 04-03-2015 View substance registered dossier
(1RS, 2SR) (+/-) Methyl trans 2,6,6,-trimethyl-3-cyclohexene-1-carboxylate
453-570-1 540734-22-3 Active Full Joint ≥ 1 to < 10 tonnes 14-03-2016 View substance registered dossier
(1RS, 2SR) (+/-) Methyl trans 2,6,6,-trimethyl-3-cyclohexene-1-carboxylate
453-570-1 540734-22-3 Active NONS Individual Tonnage data confidential 15-12-2008 View substance registered dossier
(1RS,2RS,3RS,6RS,8SR)-8-methoxytricyclo[5.2.1.0(2,6)]decane-3-carbaldehyde;(1RS,2RS,4SR,6RS,8SR)-8-methoxytricyclo[5.2.1.0(2,6)]decane-4-carbaldehyde;reaction mass of: (1RS,2RS,3SR,6RS,9SR)-9-methoxytricyclo[5.2.1.0(2,6)]decane-3-carbaldehyde
429-860-9 1228804-60-1 Active NONS Joint Tonnage data confidential 24-04-2013 View substance registered dossier
(1RS,2SR,7SR,8SR,Z)-10-ethylidene-3-oxatricyclo[6.2.1.0(2,7)]undecan-4-one;(1RS,2SR,7SR,8SR,Z)-9-ethylidene-3-oxatricyclo[6.2.1.0(2,7)]undecan-4-one;reaction mass of: (1RS,2SR,7SR,8SR,E) 9 and 10-ethylidene-3-oxatricyclo[6.2.1.0(2,7)]undecan-4-one
434-290-9 249630-78-2 Active NONS Joint Tonnage data confidential 11-01-2011 View substance registered dossier
(1RS,4Z,8E,12RS)-13-oxabicyclo[10.1.0]trideca-4,8-diene
951-761-9 55722-64-0 Active Full Joint ≥ 1 to < 10 tonnes 04-09-2020 View substance registered dossier
(1RS,4Z,8E,12RS)-13-oxabicyclo[10.1.0]trideca-4,8-diene
951-761-9 55722-64-0 Active Intermediate Joint Intermediate use only 12-02-2019 View substance registered dossier
(1S)-(+)-2-AZABICYCLO[2.2.1]HEPT-5-EN-3-ONE
627-840-6 130931-83-8 Active Intermediate Joint Intermediate use only 07-12-2017 View substance registered dossier
(1S)-1-cyclopropylethanamine; (2R)-2-hydroxy-2-phenyl-acetic acid
946-290-0 2246580-61-8 Active Intermediate Joint Intermediate use only 01-10-2020 View substance registered dossier
(1S)-1-NAPHTHYLETHYLAMINE
436-100-1 - Active Intermediate Joint Intermediate use only 20-12-2017 View substance registered dossier
(1S)-1-Phenylethanaminium (2S)-2-(2-fluorobiphenyl-4-yl)propanoate
942-079-2 - No longer Valid Intermediate Individual No longer valid 05-03-2020 View substance registered dossier
(1S)-1-{(2R)-3,4-bis[(2-hexyldecanoyl)oxy]-5-oxo-2,5-dihydrofuran-2-yl}ethane-1,2-diyl bis(2-hexyldecanoate)
430-110-8 183476-82-6 Active Full Joint ≥ 1 tonnes 01-09-2011 View substance registered dossier
(1S)-2-chloro-1-methyl-2-oxoethyl acetate;(S)-(-)-2-acetoxypropionylchloride
420-610-4 36394-75-9 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(1S)-2-methyl-2,5-diazobicyclo[2.2.1]heptane dihydrobromide
CP-84,203-4; DFX-5S
411-000-9 125224-62-6 Active NONS Joint Tonnage data confidential 10-05-2013 View substance registered dossier
(1S)-3,7,7-trimethylbicyclo[4.1.0]hept-3-ene
207-856-6 498-15-7 Active Full Joint ≥ 1 000 to < 10 000 tonnes 29-04-2021 View substance registered dossier
(1S, 5R) – (-)- 2-oxabicyclo(3.3.0.) oct-6-en-3-one
610-106-4 43119-28-4 Active Intermediate Joint Intermediate use only 11-06-2020 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Patheon Austria GmbH & Co KG St. Peterstrasse 25 A-4020 Linz Austria Austria Active (1R,4S)-6-tert-butoxy-4-(tert-butyldimethylsilyloxy)-6-oxo-1-(2-(thiophen-2-yl)acetamido)hexylboronic acid, (+)-pinanediol ester 812-137-0 1681053-97-3 - View substance registered dossier
CURIA SPAIN, S.A.U. Parque Tecnológico de Boecillo, parcela 105 47151 Boecillo Valladolid Spain Spain Active (1R,5aR,10R,11aS)-1-acetyl-10-[4-(dimethylamino)phenyl]-5a-hydroxy-11a-methyl-3,3a,3b,4,5,6,8,9,10,11-decahydro-2H-spiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolan]-1-yl acetate 615-905-1 730962-28-4 2018 View substance registered dossier
Destilerías Muñoz Gálvez, S.A. Avda. Ciudad de Almería, 162 E30010 Murcia Murcia Spain Spain Active (1R,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene 232-087-8 7785-70-8 2019 View substance registered dossier
DESTILACIONES BORDAS CHINCHURRETA, S.A. C/ Acueducto, 4-6 Pol. Ind. Ctra la Isla 41703 Dos Hermanas (Sevilla) Spain Spain Active (1R,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene 232-087-8 7785-70-8 2019 View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Cease Manufacture (1R,5R)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene 232-087-8 7785-70-8 2017 View substance registered dossier
TAKASAGO TICSA-Producer/Importer Avenida de Mazarrón, 49 30120 El Palmar Murcia Spain Spain Active (1R,6S)-2,2,6-trimethylcyclohexane-1-carboxylic acid 944-682-6 - - View substance registered dossier
Symrise AG Mühlenfeldstraße 1 37603 Holzminden Germany Germany Active (1R,8S)-2,2,7,7-tetramethyltricyclo[6.2.1.0^{1,6}]undec-5-en-4-one 942-035-2 - - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (1RS, 2SR) (+/-) Methyl trans 2,6,6,-trimethyl-3-cyclohexene-1-carboxylate 453-570-1 540734-22-3 2016 View substance registered dossier
[Confidential] - - - (1RS, 2SR) (+/-) Methyl trans 2,6,6,-trimethyl-3-cyclohexene-1-carboxylate 453-570-1 540734-22-3 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (1RS, 2SR) (+/-) Methyl trans 2,6,6,-trimethyl-3-cyclohexene-1-carboxylate 453-570-1 540734-22-3 - View substance registered dossier
FIRMENICH GRASSE SAS OR 2 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (1RS,2RS,3RS,6RS,8SR)-8-methoxytricyclo[5.2.1.0(2,6)]decane-3-carbaldehyde;(1RS,2RS,4SR,6RS,8SR)-8-methoxytricyclo[5.2.1.0(2,6)]decane-4-carbaldehyde;reaction mass of: (1RS,2RS,3SR,6RS,9SR)-9-methoxytricyclo[5.2.1.0(2,6)]decane-3-carbaldehyde 429-860-9 1228804-60-1 2013 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (1RS,2RS,3RS,6RS,8SR)-8-methoxytricyclo[5.2.1.0(2,6)]decane-3-carbaldehyde;(1RS,2RS,4SR,6RS,8SR)-8-methoxytricyclo[5.2.1.0(2,6)]decane-4-carbaldehyde;reaction mass of: (1RS,2RS,3SR,6RS,9SR)-9-methoxytricyclo[5.2.1.0(2,6)]decane-3-carbaldehyde 429-860-9 1228804-60-1 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant UK competent national authority. - - Active (1RS,2SR,7SR,8SR,Z)-10-ethylidene-3-oxatricyclo[6.2.1.0(2,7)]undecan-4-one;(1RS,2SR,7SR,8SR,Z)-9-ethylidene-3-oxatricyclo[6.2.1.0(2,7)]undecan-4-one;reaction mass of: (1RS,2SR,7SR,8SR,E) 9 and 10-ethylidene-3-oxatricyclo[6.2.1.0(2,7)]undecan-4-one 434-290-9 249630-78-2 - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (1RS,2SR,7SR,8SR,Z)-10-ethylidene-3-oxatricyclo[6.2.1.0(2,7)]undecan-4-one;(1RS,2SR,7SR,8SR,Z)-9-ethylidene-3-oxatricyclo[6.2.1.0(2,7)]undecan-4-one;reaction mass of: (1RS,2SR,7SR,8SR,E) 9 and 10-ethylidene-3-oxatricyclo[6.2.1.0(2,7)]undecan-4-one 434-290-9 249630-78-2 2011 View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (1RS,4Z,8E,12RS)-13-oxabicyclo[10.1.0]trideca-4,8-diene 951-761-9 55722-64-0 - View substance registered dossier
FIRMENICH PRODUCTION S.A.S. BP 23 766, route Roger Firmenich 40260 Castets France France Active (1RS,4Z,8E,12RS)-13-oxabicyclo[10.1.0]trideca-4,8-diene 951-761-9 55722-64-0 - View substance registered dossier
[Confidential] - - - (1RS,4Z,8E,12RS)-13-oxabicyclo[10.1.0]trideca-4,8-diene 951-761-9 55722-64-0 - View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active (1S)-(+)-2-AZABICYCLO[2.2.1]HEPT-5-EN-3-ONE 627-840-6 130931-83-8 - View substance registered dossier
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (1S)-1-cyclopropylethanamine; (2R)-2-hydroxy-2-phenyl-acetic acid 946-290-0 2246580-61-8 - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active (1S)-1-cyclopropylethanamine; (2R)-2-hydroxy-2-phenyl-acetic acid 946-290-0 2246580-61-8 - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (1S)-1-NAPHTHYLETHYLAMINE 436-100-1 - 2017 View substance registered dossier
Aesica Pharmaceuticals Limited Windmill Industrial Estate Shotton Lane NE23 3JL Cramlington Northumberland United Kingdom United Kingdom No longer Valid (1S)-1-Phenylethanaminium (2S)-2-(2-fluorobiphenyl-4-yl)propanoate 942-079-2 - 2021 View substance registered dossier
Only representative (No publishable name) - - Active (1S)-1-{(2R)-3,4-bis[(2-hexyldecanoyl)oxy]-5-oxo-2,5-dihydrofuran-2-yl}ethane-1,2-diyl bis(2-hexyldecanoate) 430-110-8 183476-82-6 2011 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active (1S)-1-{(2R)-3,4-bis[(2-hexyldecanoyl)oxy]-5-oxo-2,5-dihydrofuran-2-yl}ethane-1,2-diyl bis(2-hexyldecanoate) 430-110-8 183476-82-6 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. - - Active (1S)-2-chloro-1-methyl-2-oxoethyl acetate;(S)-(-)-2-acetoxypropionylchloride 420-610-4 36394-75-9 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active (1S)-2-chloro-1-methyl-2-oxoethyl acetate;(S)-(-)-2-acetoxypropionylchloride 420-610-4 36394-75-9 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active (1S)-2-methyl-2,5-diazobicyclo[2.2.1]heptane dihydrobromide 411-000-9 125224-62-6 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (1S)-2-methyl-2,5-diazobicyclo[2.2.1]heptane dihydrobromide 411-000-9 125224-62-6 2013 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (1S)-2-methyl-2,5-diazobicyclo[2.2.1]heptane dihydrobromide 411-000-9 125224-62-6 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (1S)-2-methyl-2,5-diazobicyclo[2.2.1]heptane dihydrobromide 411-000-9 125224-62-6 - View substance registered dossier
Commentz & Co. GmbH & Co. Billbrookdeich 122 22113 Hamburg Germany Germany Active (1S)-3,7,7-trimethylbicyclo[4.1.0]hept-3-ene 207-856-6 498-15-7 - View substance registered dossier
ERNESTO VENTOS, S.A. Carretera Reial 120B 08960 Sant Just Desvern Spain Spain Active (1S)-3,7,7-trimethylbicyclo[4.1.0]hept-3-ene 207-856-6 498-15-7 - View substance registered dossier
Frey + Lau GmbH Immenhacken 12 DE-24558 Henstedt-Ulzburg Germany Germany Active (1S)-3,7,7-trimethylbicyclo[4.1.0]hept-3-ene 207-856-6 498-15-7 - View substance registered dossier
[Confidential] - - - (1S)-3,7,7-trimethylbicyclo[4.1.0]hept-3-ene 207-856-6 498-15-7 - View substance registered dossier
Destilerías Muñoz Gálvez, S.A. Avda. Ciudad de Almería, 162 E30010 Murcia Murcia Spain Spain Active (1S)-3,7,7-trimethylbicyclo[4.1.0]hept-3-ene 207-856-6 498-15-7 2017; 2018; 2019 View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Active (1S)-3,7,7-trimethylbicyclo[4.1.0]hept-3-ene 207-856-6 498-15-7 2010; 2016; 2017; 2018; 2019; 2021 View substance registered dossier
Weissmeer Baltische Import-Export GmbH Colonnaden 51 20354 Hamburg Germany Germany Active (1S)-3,7,7-trimethylbicyclo[4.1.0]hept-3-ene 207-856-6 498-15-7 2018 View substance registered dossier
SONEAS Chemicals Ltd. Banyaleg Str. 47-59. H-1225 Budapest Hungary Hungary Active (1S, 5R) – (-)- 2-oxabicyclo(3.3.0.) oct-6-en-3-one 610-106-4 43119-28-4 2020 View substance registered dossier

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

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