Registered substances

Registered substances

Registered substances

In this table, you will find all public data submitted to ECHA in REACH registration dossiers by substance manufacturers, importers, or their representatives, as laid out by the REACH Regulation (see Understanding REACH regulation).

ECHA makes available this information as REACH registered substance factsheets, which contain the full set of non-confidential information from related registration dossiers for a substance. Depending on the number of registrations that have been made for a substance, one factsheet can thus represent data from anything between hundreds of registration dossiers in a joint submission, to data from just one registration dossier.

As noted in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission. Please also note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).

In the portal results table are presented:

  • Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
  • Registration status – indicating the calculated registration status: Active - being actively manufactured or imported to the EEA; Cease manufacture - is no longer being manufactured or imported, but still considered to have a valid registration under REACH, and capable of resuming manufacture or import at any time; or No longer valid - no longer considered registered under REACH and not currently permitted to be manufactured or imported to the EEA unless and until properly registered again.
  • Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
  • Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
  • Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
  • Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
  • Link to the full factsheet.

A subset of the key chemical properties (physico-chemical, environmental fate, ecotoxicological and toxicological data) of registered substances can be searched and accessed via the OECD eChemPortal.

Please note:
  • The ‘Substance has nanoform’ search filter returns all factsheets containing any data related to nanomaterials. NB: This does not mean that a registration covering nanoforms has been submitted in line with the revised annexes of REACH. Since 1 January 2020, before manufacturing or importing a nanoform of a substance, the operators concerned must submit the required nano-specific information to ECHA in a new or updated registration dossier.
Last updated 06 August 2021. Database contains 23376 unique substances and contains information from 104385 dossiers.
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Details
(1S)-1-cyclopropylethanamine; (2R)-2-hydroxy-2-phenyl-acetic acid
946-290-0 - Active Intermediate Joint Intermediate use only 01-10-2020 View substance registered dossier
(1S)-1-NAPHTHYLETHYLAMINE
436-100-1 - Active Intermediate Joint Intermediate use only 20-12-2017 View substance registered dossier
(1S)-1-Phenylethanaminium (2S)-2-(2-fluorobiphenyl-4-yl)propanoate
942-079-2 - No longer Valid Intermediate Individual No longer valid 05-03-2020 View substance registered dossier
(1S)-1-{(2R)-3,4-bis[(2-hexyldecanoyl)oxy]-5-oxo-2,5-dihydrofuran-2-yl}ethane-1,2-diyl bis(2-hexyldecanoate)
430-110-8 183476-82-6 Active Full Joint ≥ 1 tonnes 01-09-2011 View substance registered dossier
(1S)-2,3,4,6-TETRA-O-ACETYL-1,5-ANHYDRO-1-(3-{[5-(4-FLUOROPHENYL)THIOPHEN-2-YL]METHYL}-4-METHYLPHENYL)-D-GLUCITOL
617-901-5 866607-35-4 Active Full Joint ≥ 1 to < 10 tonnes 23-06-2020 View substance registered dossier
(1S)-2,3,4,6-TETRA-O-ACETYL-1,5-ANHYDRO-1-(3-{[5-(4-FLUOROPHENYL)THIOPHEN-2-YL]METHYL}-4-METHYLPHENYL)-D-GLUCITOL
617-901-5 866607-35-4 Cease Manufacture Intermediate Individual Cease manufacture 10-10-2014 View substance registered dossier
(1S)-2,3,4,6-tetra-O-acetyl-1,5-anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucitol
930-010-9 461432-25-7 Active Full Joint ≥ 10 to < 100 tonnes 04-04-2018 View substance registered dossier
(1S)-2-(benzylamino)-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol
603-316-2 129050-27-7 Active Full Joint ≥ 1 to < 10 tonnes 16-01-2018 View substance registered dossier
(1S)-2-(benzylamino)-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol
603-316-2 129050-27-7 Active Intermediate Individual Intermediate use only 20-11-2014 View substance registered dossier
(1S)-2-(benzyl{(2S)-2-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl}amino)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol hydrochloride (1:1)
807-022-7 1224567-85-4 Active Intermediate Joint Intermediate use only 29-05-2018 View substance registered dossier
(1S)-2-(benzyl{(2S)-2-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl}amino)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol hydrochloride (1:1)
807-022-7 1224567-85-4 Active Intermediate Individual Intermediate use only 17-10-2014 View substance registered dossier
(1S)-2-chloro-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol
807-023-2 1315508-95-2 Active Intermediate Joint Intermediate use only 20-02-2017 View substance registered dossier
(1S)-2-chloro-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol
807-024-8 1315508-96-3 Active Intermediate Joint Intermediate use only 20-02-2017 View substance registered dossier
(1S)-2-chloro-1-methyl-2-oxoethyl acetate; (S)-(-)-2-acetoxypropionylchloride
420-610-4 36394-75-9 Active NONS Joint Tonnage data confidential 10-11-2008 View substance registered dossier
(1S)-2-methyl-2,5-diazobicyclo[2.2.1]heptane dihydrobromide
411-000-9 125224-62-6 Active NONS Joint Tonnage data confidential 10-05-2013 View substance registered dossier
(1S)-3,7,7-trimethylbicyclo[4.1.0]hept-3-ene
207-856-6 498-15-7 Active Full Joint ≥ 1 000 to < 10 000 tonnes 29-04-2021 View substance registered dossier
(1S)-3-(dimethylamino)-1-(2-thienyl)propan-1-ol
603-565-7 132335-44-5 Active Intermediate Individual Intermediate use only 18-11-2011 View substance registered dossier
(1S)-3-(dimethylamino)-1-(2-thienyl)propan-1-ol
603-565-7 132335-44-5 Active Intermediate Individual Intermediate use only 19-02-2014 View substance registered dossier
(1S,1'R)-[1-(3',3'-dimethyl-1'-cyclohexyl)ethoxycarbonyl]methyl propanoate
431-700-8 259823-90-0 Active NONS Individual Tonnage data confidential 10-11-2008 View substance registered dossier
(1S,1'R)-[1-(3',3'-dimethyl-1'-cyclohexyl)ethoxycarbonyl]methyl propanoate
431-700-8 259823-90-0 Active Full Joint ≥ 0 tonnes 24-06-2021 View substance registered dossier
Registrant/Supplier Address Country Registration Status Name EC / List no. CAS no. Last update year Details
Boehringer Ingelheim Pharma GmbH & Co. KG Binger Strasse 173 55216 Ingelheim am Rhein Germany Germany Active (1S)-1-cyclopropylethanamine; (2R)-2-hydroxy-2-phenyl-acetic acid 946-290-0 - - View substance registered dossier
Bidachem S.p.A. S.S. 11 Padana Superiore No. 8 24040 Fornovo San Giovanni BG Italy Italy Active (1S)-1-cyclopropylethanamine; (2R)-2-hydroxy-2-phenyl-acetic acid 946-290-0 - - View substance registered dossier
Arran Chemical Company Ltd Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland Ireland Active (1S)-1-NAPHTHYLETHYLAMINE 436-100-1 - 2017 View substance registered dossier
Aesica Pharmaceuticals Limited Windmill Industrial Estate Shotton Lane NE23 3JL Cramlington Northumberland United Kingdom United Kingdom No longer Valid (1S)-1-Phenylethanaminium (2S)-2-(2-fluorobiphenyl-4-yl)propanoate 942-079-2 - 2021 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Dutch competent national authority. - - Active (1S)-1-{(2R)-3,4-bis[(2-hexyldecanoyl)oxy]-5-oxo-2,5-dihydrofuran-2-yl}ethane-1,2-diyl bis(2-hexyldecanoate) 430-110-8 183476-82-6 - View substance registered dossier
Only representative (No publishable name) - - Active (1S)-1-{(2R)-3,4-bis[(2-hexyldecanoyl)oxy]-5-oxo-2,5-dihydrofuran-2-yl}ethane-1,2-diyl bis(2-hexyldecanoate) 430-110-8 183476-82-6 2011 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (1S)-2,3,4,6-TETRA-O-ACETYL-1,5-ANHYDRO-1-(3-{[5-(4-FLUOROPHENYL)THIOPHEN-2-YL]METHYL}-4-METHYLPHENYL)-D-GLUCITOL 617-901-5 866607-35-4 2019; 2020 View substance registered dossier
N.V. Ajinomoto OmniChem S.A. Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium Belgium Cease Manufacture (1S)-2,3,4,6-TETRA-O-ACETYL-1,5-ANHYDRO-1-(3-{[5-(4-FLUOROPHENYL)THIOPHEN-2-YL]METHYL}-4-METHYLPHENYL)-D-GLUCITOL 617-901-5 866607-35-4 2019 View substance registered dossier
SK BIOTEK IRELAND LIMITED Watery Lane Swords K67 AY91 Swords Co. Dublin Ireland Ireland Active (1S)-2,3,4,6-tetra-O-acetyl-1,5-anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucitol 930-010-9 461432-25-7 2011; 2015; 2018 View substance registered dossier
Siegfried St. Vulbas SAS 530, allée de la Luye 01150 SAINT VULBAS France France Active (1S)-2,3,4,6-tetra-O-acetyl-1,5-anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucitol 930-010-9 461432-25-7 2016 View substance registered dossier
Janssen Pharmaceutica N.V. Turnhoutseweg 30 2340 Beerse Belgium Belgium Active (1S)-2-(benzylamino)-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol 603-316-2 129050-27-7 2018 View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active (1S)-2-(benzylamino)-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol 603-316-2 129050-27-7 - View substance registered dossier
F.I.S. Fabbrica Italiana Sintetici S.p.a. Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy Italy Active (1S)-2-(benzyl{(2S)-2-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl}amino)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol hydrochloride (1:1) 807-022-7 1224567-85-4 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active (1S)-2-(benzyl{(2S)-2-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]-2-hydroxyethyl}amino)-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol hydrochloride (1:1) 807-022-7 1224567-85-4 - View substance registered dossier
Corden Pharma Bergamo S.p.A. Via Bergamo, 121 IT-24047 Treviglio BG Italy Italy Active (1S)-2-chloro-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol 807-023-2 1315508-95-2 - View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active (1S)-2-chloro-1-[(2R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol 807-023-2 1315508-95-2 2017 View substance registered dossier
cordenpharma chenove 47, rue de Longvic 21300 Chenôve France France Active (1S)-2-chloro-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol 807-024-8 1315508-96-3 2017 View substance registered dossier
Corden Pharma Bergamo S.p.A. Via Bergamo, 121 IT-24047 Treviglio BG Italy Italy Active (1S)-2-chloro-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol 807-024-8 1315508-96-3 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active (1S)-2-chloro-1-methyl-2-oxoethyl acetate; (S)-(-)-2-acetoxypropionylchloride 420-610-4 36394-75-9 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Spanish competent national authority. - - Active (1S)-2-chloro-1-methyl-2-oxoethyl acetate; (S)-(-)-2-acetoxypropionylchloride 420-610-4 36394-75-9 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Italian competent national authority. - - Active (1S)-2-methyl-2,5-diazobicyclo[2.2.1]heptane dihydrobromide 411-000-9 125224-62-6 - View substance registered dossier
Pfizer Ireland Pharmaceuticals n/a P43 X3336 Ringaskiddy Cork Ireland Ireland Active (1S)-2-methyl-2,5-diazobicyclo[2.2.1]heptane dihydrobromide 411-000-9 125224-62-6 2013 View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant German competent national authority. - - Active (1S)-2-methyl-2,5-diazobicyclo[2.2.1]heptane dihydrobromide 411-000-9 125224-62-6 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant Irish competent national authority. - - Active (1S)-2-methyl-2,5-diazobicyclo[2.2.1]heptane dihydrobromide 411-000-9 125224-62-6 - View substance registered dossier
Commentz & Co. GmbH & Co. Billbrookdeich 122 22113 Hamburg Germany Germany Active (1S)-3,7,7-trimethylbicyclo[4.1.0]hept-3-ene 207-856-6 498-15-7 - View substance registered dossier
ERNESTO VENTOS, S.A. Carretera Reial 120B 08960 Sant Just Desvern Spain Spain Active (1S)-3,7,7-trimethylbicyclo[4.1.0]hept-3-ene 207-856-6 498-15-7 - View substance registered dossier
Frey + Lau GmbH Immenhacken 12 DE-24558 Henstedt-Ulzburg Germany Germany Active (1S)-3,7,7-trimethylbicyclo[4.1.0]hept-3-ene 207-856-6 498-15-7 - View substance registered dossier
[Confidential] - - - (1S)-3,7,7-trimethylbicyclo[4.1.0]hept-3-ene 207-856-6 498-15-7 - View substance registered dossier
Destilerías Muñoz Gálvez, S.A. Avda. Ciudad de Almería, 162 E30010 Murcia Murcia Spain Spain Active (1S)-3,7,7-trimethylbicyclo[4.1.0]hept-3-ene 207-856-6 498-15-7 2017; 2018; 2019 View substance registered dossier
LES DERIVES RESINIQUES ET TERPENIQUES 30 rue Gambetta B.P. 206 40105 Dax Cedex France France Active (1S)-3,7,7-trimethylbicyclo[4.1.0]hept-3-ene 207-856-6 498-15-7 2010; 2016; 2017; 2018; 2019; 2021 View substance registered dossier
Weissmeer Baltische Import-Export GmbH Colonnaden 51 20354 Hamburg Germany Germany Active (1S)-3,7,7-trimethylbicyclo[4.1.0]hept-3-ene 207-856-6 498-15-7 2018 View substance registered dossier
SYNTESIA CHEMIE GmbH Martinistr. 13 20251 Hamburg Germany Germany Active (1S)-3-(dimethylamino)-1-(2-thienyl)propan-1-ol 603-565-7 132335-44-5 - View substance registered dossier
Esteve Quimica, S.A. Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain Spain Active (1S)-3-(dimethylamino)-1-(2-thienyl)propan-1-ol 603-565-7 132335-44-5 - View substance registered dossier
Former NONS notifier unknown to ECHA - Contact the relevant French competent national authority. - - Active (1S,1'R)-[1-(3',3'-dimethyl-1'-cyclohexyl)ethoxycarbonyl]methyl propanoate 431-700-8 259823-90-0 - View substance registered dossier
[Confidential] - - - (1S,1'R)-[1-(3',3'-dimethyl-1'-cyclohexyl)ethoxycarbonyl]methyl propanoate 431-700-8 259823-90-0 - View substance registered dossier
FIRMENICH GRASSE SAS OR 1 Parc Industriel Les Bois de Grasse 06130 Grasse France France Active (1S,1'R)-[1-(3',3'-dimethyl-1'-cyclohexyl)ethoxycarbonyl]methyl propanoate 431-700-8 259823-90-0 2011; 2012; 2020; 2021 View substance registered dossier

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