Registration Dossier
Registration Dossier
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Reaction products of (E)-5-((4-amino-5-methoxy-2-methylphenyl)diazenyl)-3-((phenylsulfonyl)oxy)naphthalene-2,7-disulfonic acid condensate with cyanurchloride, then condensate with (E)-7-amino-4-hydroxy-3-((2-methoxy-5-sulfophenyl)diazenyl)naphthalene-2-sulfonic acid, finally condensate with aniline, potassium salts
EC number: 948-912-6 | CAS number: -
Endpoint summary
Administrative data
Description of key information
LD50 > 3170 mg/kg
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Acute oral toxicity was assessed in rats upon administration of a single oral dose. Doses of 1000, 2150 and 3170 mg/kg were tested and observations were continued up to day 7. No mortality was seen and recovery of dose-related symptoms in terms of sedation, dyspnoea, exophthalmus, curved position and ruffled fur occurred within 6 days.
Justification for classification or non-classification
According to the CLP Regulation (EC 1272/2008), substances can be allocated to one of four toxicity categories based on acute toxicity by oral, dermal or inhalation route according to numeric criteria. Acute toxicity values are expressed as LD50 (oral, dermal) or LC50 (inhalation) values as well as acute toxicity estimates (ATE).
In the available study in rats, oral LD50 value above 2000 mg/kg bw was found. Accordingly, target substance was not classified for acute oral toxicity in the CLP Regulation (EC 1272/2008).
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