Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 948-406-5 | CAS number: -
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- June to October 2019
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 020
- Report date:
- 2020
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - HPLC Method)
- Version / remarks:
- version May 2008
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Version / remarks:
- version April 2004
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Cyclopentadiene
- EC Number:
- 208-835-4
- EC Name:
- Cyclopentadiene
- Cas Number:
- 542-92-7
- Molecular formula:
- C5H6
- IUPAC Name:
- cyclopenta-1,3-diene
- Reference substance name:
- 4-vinylcyclohexene
- EC Number:
- 202-848-9
- EC Name:
- 4-vinylcyclohexene
- Cas Number:
- 100-40-3
- Molecular formula:
- C8H12
- IUPAC Name:
- 4-vinylcyclohexene
- Reference substance name:
- 5-ethylidene-8,9,10-trinorborn-2-ene
- EC Number:
- 240-347-7
- EC Name:
- 5-ethylidene-8,9,10-trinorborn-2-ene
- Cas Number:
- 16219-75-3
- Molecular formula:
- C9H12
- IUPAC Name:
- 5-ethylidenebicyclo[2.2.1]hept-2-ene
- Reference substance name:
- Cycloocta-1,5-diene
- EC Number:
- 203-907-1
- EC Name:
- Cycloocta-1,5-diene
- Cas Number:
- 111-78-4
- Molecular formula:
- C8H12
- IUPAC Name:
- cycloocta-1,5-diene
- Reference substance name:
- 3a,4,7,7a-tetrahydro-1H-indene
- EC Number:
- 221-260-3
- EC Name:
- 3a,4,7,7a-tetrahydro-1H-indene
- Cas Number:
- 3048-65-5
- Molecular formula:
- C9H12
- IUPAC Name:
- 3a,4,7,7a-tetrahydro-1H-indene
- Reference substance name:
- 5-methylbicyclo[2.2.1]hept-2-ene
- EC Number:
- 212-509-7
- EC Name:
- 5-methylbicyclo[2.2.1]hept-2-ene
- Cas Number:
- 822-96-8
- Molecular formula:
- C8H12
- IUPAC Name:
- 5-methylbicyclo[2.2.1]hept-2-ene
- Reference substance name:
- 3a,4,7,7a-tetrahydro-4,7-methanoindene
- EC Number:
- 201-052-9
- EC Name:
- 3a,4,7,7a-tetrahydro-4,7-methanoindene
- Cas Number:
- 77-73-6
- Molecular formula:
- C10H12
- IUPAC Name:
- 3a,4,7,7a-tetrahydro-4,7-methanoindene,
- Reference substance name:
- 3a,4,7,7a-tetrahydro-4-methyl-1H-indene
- EC Number:
- 231-021-5
- EC Name:
- 3a,4,7,7a-tetrahydro-4-methyl-1H-indene
- Cas Number:
- 7413-02-7
- Molecular formula:
- C10H14
- IUPAC Name:
- 4-methyl-3a,4,7,7a-tetrahydro-1H-indene
- Reference substance name:
- Combination of: 6-(cyclohex-3-en-1-yl)bicyclo[2.2.1]hept-2-ene 2-vinyl-1,2,3,4,4a,5,8,8a-octahydro-1,4-methanonaphthalene 6-vinyl-1,4,4a,5,6,7,8,8a-octahydro-1,4-methanonaphthalene 2-vinyl-1,2,3,4,4a,5,8,8a-octahydro-1,4:5,8-dimethanonaphthalene 2,2'-bi(bicyclo[2.2.1]heptane-5,5'-diene) 3a,4,4a,5,8,8a,9,9a-octahydro-1H-5,8-methanocyclopenta[b]naphthalene 4,4a,4b,5,8,8a,9,9a-octahydro-1H-1,4-methanofluorene
- Molecular formula:
- C13H18 to C14H18
- IUPAC Name:
- Combination of: 6-(cyclohex-3-en-1-yl)bicyclo[2.2.1]hept-2-ene 2-vinyl-1,2,3,4,4a,5,8,8a-octahydro-1,4-methanonaphthalene 6-vinyl-1,4,4a,5,6,7,8,8a-octahydro-1,4-methanonaphthalene 2-vinyl-1,2,3,4,4a,5,8,8a-octahydro-1,4:5,8-dimethanonaphthalene 2,2'-bi(bicyclo[2.2.1]heptane-5,5'-diene) 3a,4,4a,5,8,8a,9,9a-octahydro-1H-5,8-methanocyclopenta[b]naphthalene 4,4a,4b,5,8,8a,9,9a-octahydro-1H-1,4-methanofluorene
- Reference substance name:
- 4,4a,4b,5,8,8a,9,9a-octahydro-1H-1,4-methanofluorene OR 4,4a,4b,5,8,8a,9,9a-octahydro-1H-1,4:5,8-dimethanofluorene
- Molecular formula:
- C14H18 to C15H18
- IUPAC Name:
- 4,4a,4b,5,8,8a,9,9a-octahydro-1H-1,4-methanofluorene OR 4,4a,4b,5,8,8a,9,9a-octahydro-1H-1,4:5,8-dimethanofluorene
- Test material form:
- liquid
- Details on test material:
- Pale yellow liquid. Batch no: 776859. Storage room temperature in the dark.
Constituent 1
Constituent 2
Constituent 3
Constituent 4
Constituent 5
Constituent 6
Constituent 7
Constituent 8
Constituent 9
Constituent 10
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficientopen allclose all
- Type:
- log Pow
- Partition coefficient:
- >= 0.3 - <= 6.5
- Temp.:
- 30 °C
- pH:
- ca. 7.4
- Remarks on result:
- other: range for whole composition
- Type:
- log Pow
- Partition coefficient:
- >= 4.2 - <= 5.6
- Temp.:
- 30 °C
- pH:
- ca. 7.4
- Remarks on result:
- other: range for middle 80% of composition
- Details on results:
- More than 20 peaks were observed in the chromatograms. The first peak had a logPow of <0.3 whiilst the last had a logPow>6.5. The middle 80% (10-90%) eluted with an indicated LogPow range of 4.2 to 5.6. The largest peak accounted for 60% of the composition (likely to be BCND) and this had a logPow of 4.4. ~95% of the components in the composition had a logPow>=3.
Applicant's summary and conclusion
- Executive summary:
In a guideline and GLP study, the partition coefficient of the UVCB substance THI-RF60 was, as expected, found to vary over quite a wide range. The overall range of the logPow of the components present was from <0.3 to >6.5. 96% of the components showed a logPow >=3 and the middle 80% of the composition consistent of components with logPow values in the range >=4.2 to <=5.6.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
