Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 16 October 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- no
- Type of method:
- column elution method
- Water solubility:
- < 0.003 mg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 6.5
- Details on results:
- The concentration of the sample was shown to be below the limit of quantification at both flow rates.
- Conclusions:
- The water solubility of the substance is < 0.0025 mg/L.
- Executive summary:
In a column elution test the substance was shown to have a water solubility below the limit of quantification of the analytical method (CC-MS) at flow rates of 1 and 2 ml/min. The water solubility is < 0.0025 mg/L.
Reference
Date/Time |
Temp (oC) |
Column A |
|
|
Column B |
|
|
|
|
Flow Rate (mL/min) |
Time (min) |
Calculated Conc (mg/L) |
Flow rate (mL/min) |
Time (min) |
Calculated Conc (mg/L) |
16/10/17 07:50 |
20+/-0.5oC |
1 |
40 |
< 0.0025 |
2 |
40 |
0.0172 |
16/10/17 08:10 |
20+/-0.5oC |
1 |
No Sample at time point |
2 |
60 |
< 0.0025 |
|
16/10/17 08:30 |
20+/-0.5oC |
1 |
80 |
< 0.0025 |
2 |
80 |
< 0.0025 |
16/10/17 08:50 |
20+/-0.5oC |
1 |
No Sample at time point |
2 |
100 |
< 0.0025 |
|
16/10/17 09:10 |
20+/-0.5oC |
1 |
120 |
< 0.0025 |
2 |
120 |
< 0.0025 |
16/10/17 09:30 |
20+/-0.5oC |
1 |
No Sample at time point |
2 |
140 |
< 0.0025 |
|
16/10/17 09:50 |
20+/-0.5oC |
1 |
160 |
< 0.0025 |
2 |
160 |
< 0.0025 |
16/10/17 10:10 |
20+/-0.5oC |
1 |
No Sample at time point |
2 |
180 |
< 0.0025 |
|
16/10/17 10:30 |
20+/-0.5oC |
1 |
200 |
< 0.0025 |
2 |
200 |
< 0.0025 |
Description of key information
In a column elution test the substance was shown to have a water solubility below the limit of quantification of the analytical method (CC-MS) at flow rates of 1 and 2 ml/min. The water solubility is < 0.0025 mg/L.
Key value for chemical safety assessment
- Water solubility:
- 0.003 mg/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
