Fatty acids C16-18 (even numbered) manganese(II) salts

Water solubility

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

transformation / dissolution of metals and inorganic metal compounds

Type of information:

experimental study

Adequacy of study:

key study

Study period:

April to June 2022

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Series on Testing and Assessment No. 29 (23-Jul-2001): Guidance document on transformation/dissolution of metals and metal compounds in aqueous media

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Key result

Type of test:

screening transformation/dissolution test - sparingly soluble metal compounds

Mean dissolved conc.:

> 0 - < 1.7 mg/L

Element analysed:

Manganese

Loading of aqueous phase:

100

Incubation duration:

24 h

Test conditions:

according to OECD TG 29

Details on results:

Awaiting final results from the laboratory

Conclusions:

Water solubility is <1.7mg/L

Reference 2

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

12 to 13 August 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

GLP compliance:

not specified

Type of method:

flask method

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Nitika Pharmaceutical Specialities Pvt. Ltd.
- Expiration date of the lot/batch: no data
- Purity test date: no data

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material:
- Stability under test conditions:
- Solubility and stability of the test substance in the solvent/vehicle:
- Reactivity of the test substance with the solvent/vehicle of the cell culture medium:

TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing:
- Preliminary purification step (if any):
- Final dilution of a dissolved solid, stock liquid or gel:
- Final preparation of a solid:

FORM AS APPLIED IN THE TEST (if different from that of starting material)

TYPE OF BIOCIDE/PESTICIDE FORMULATION (if applicable)

OTHER SPECIFICS:
- measurement of pH, osmolality, and precipitate in the culture medium to which the test chemical is added:
- other information:

Key result

Water solubility:

< 0.17 mg/L

Conc. based on:

test mat.

Temp.:

20 °C

pH:

7.54

Details on results:

The water solubility was estimated as < 0.17 mg/L. This concentration is below the limit of detection of the analytical method available. As a result software estimation was applied.

The prediction software uses SMILES input to calculate the Water Solubility.
In accordance with test guidance the water solubility was estimated using WSKOW v1.42 as: Water Solubility at 25°C = 1.363 x 10-11 mg.L-1 (estimated)

Conclusions:

The prediction software uses SMILES input to calculate the Water Solubility.
In accordance with test guidance the water solubility was estimated using WSKOW v1.42 as: Water Solubility at 25°C = 1.363 x 10-11 mg.L-1 (estimated)

Description of key information

The prediction software uses SMILES input to calculate the Water Solubility.

In accordance with test guidance the water solubility was estimated using WSKOW v1.42 as:

Water Solubility at 25°C = 1.363 x 10^-11mg.L^-1(estimated)

Key value for chemical safety assessment

Water solubility:

0.17 mg/L

at the temperature of:

20 °C