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Physical & Chemical properties

Partition coefficient

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
09.08. - 10.08.2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient - HPLC Method)
Version / remarks:
Council regulation (EC) No 440/2008
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Version / remarks:
Adopted 13 April 2004
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
other: Quantitative analytical methods are not required and only the determination of retention times is necessary.
Key result
Type:
log Pow
Partition coefficient:
4.38
Temp.:
23 °C
pH:
6.5
Conclusions:
Partition coefficient (log P) of the test substance Pigment Yellow 4 is:log Pow = 4.38 ± 0.71 (pH 6.5, 23°C)  
Executive summary:

The partition coefficient of the test substance, Pigment Yellow 4, was determined.

Based on the results of the preliminary estimation of the partition coefficient by a calculation method, the HPLC method was used for the main experiment.

The procedure was performed according to Method A.8. – Partition Coefficient, Council Regulation (EC) No.440/2008, Published in O.J. L 142, 2008.

Partition coefficient (log P) of the test substance Pigment Yellow 4 is:

log Pow = 4.38 ± 0.71 (pH 6.5, 23°C)  

Description of key information

The procedure was performed according to Method A.8. – Partition Coefficient, Council Regulation (EC) No.440/2008, Published in O.J. L 142, 2008.

Partition coefficient (log P) of the test substance Pigment Yellow 4 is:

log Pow = 4.38 ± 0.71 (pH 6.5, 23°C)  

Key value for chemical safety assessment

Log Kow (Log Pow):
4.38
at the temperature of:
23 °C

Additional information