Registration Dossier
Registration Dossier
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EC number: 947-384-4 | CAS number: -
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- October 12, 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Guideline 105
- Principles of method if other than guideline:
- The flask method approach for determining solubility in water was used, but using octanol as the solvent rather than water.
- GLP compliance:
- no
- Medium:
- n-octanol
- Solubility:
- 23.9 g/L
- Temp.:
- 20 °C
- Test substance stable:
- not determined
- Details on results:
- - Other: Additional test substance had to be added as the solubility from the pretest was incorrect due to the slow kinetics of dissolution of the test substance in octanol.
- Conclusions:
- The solubility of the test substance in octanol was 23.9 g/L at 20 °C.
- Executive summary:
The solubility of the test susbtance in octanol was determined. The study was done in a similar methodology as OECD Guideline 105 for determining the solubility of substances in water, only octanol was used as the solvent. The study showed that the test substance dissolves slowly in octanol. The solubility of the test substance in octanol was 23.9 g/L at 20 °C.
Reference
Description of key information
23.9 g/L at 20 °C in n-Octanol (OECD Guideline 105, flask method)
Key value for chemical safety assessment
Additional information
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