Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 946-155-6 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
In aquatic invertebrates (D. Magna) the 48-h EC50 value is > 5 mg/L (nominal).
Key value for chemical safety assessment
Additional information
The acute toxicity to aquatic invertebrates was determined in a study according to OECD guideline No 202 and in compliance with GLP criteria (BASF SE, 2015). In this study daphnids (D. magna, 20 per concentration) were exposed to nominal concentrations of 0 (control) and 5 mg/L for 48 hours under semi-static conditions (test medium renewal after 24 hours). The test concentration of 5 mg/L is the experimentally confirmed critical micelle concentration (CMC). Nominal concentrations were analytically verified via analysis of total organic carbon (TOC), measured as NPOC (Non Purgeable Organic Carbon) at the start of the exposure intervals (0 and 24 hours) and at the end of the exposure intervals (24 and 48 hours). The measured TOC concentrations remained within ± 20 % of the nominal. Therefore, effect values are expressed as nominal. Immobilisation was determined in all groups after 24 and 48 h. No immobilization or other signs of toxicity were observed throughout the test. Based on these findings the 48-h EC50 value is determined at > 5 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
