3-Mercaptopropyl-functionalized silica gel

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2018

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

3-Mercaptopropyl-functionalized silica gel

EC Number:

945-952-6

Molecular formula:

Si-CH2-CH2-CH2-SH

IUPAC Name:

3-Mercaptopropyl-functionalized silica gel

Sampling and analysis

Analytical monitoring:

not specified

Test solutions

Vehicle:

yes

Remarks:

methanol

Details on test solutions:

dissolve 50 mg of the test substance in 10 ml of methanol and the total volume was completed to 500 ml with dilution water, resulting in a concentration of 100 mg/L

Test organisms

Test organisms (species):

Daphnia magna

Study design

Test type:

static

Water media type:

freshwater

Total exposure duration:

48 h

Test conditions

Hardness:

149.1 mg/L CaCO3

Test temperature:

20.2

pH:

7.7-7.8

Dissolved oxygen:

8.0-8.1 mg/L

Reference substance (positive control):

yes

Remarks:

K2Cr2O7

Results and discussion

Effect concentrations

Key result

Duration:

48 h

Dose descriptor:

EC50

Effect conc.:

> 100 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mobility

Results with reference substance (positive control):

24h EC50 = 1.02 mg/L

Applicant's summary and conclusion

Validity criteria fulfilled:

yes