Reaction mass of (3aR*,5aS*,9aS*,9bR*)-3a,6,6,9a-Tetramethyldodecahydronaphtho[2,1-b]furan and (3aR*,5aS*,9aS*,9bS*)-3a,6,6,9a-Tetramethyldodecahydronaphtho[2,1-b]furan

Surface tension

Link to relevant study record(s)

Reference

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 2012-11-02 to 2012-11-06

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

The study was conducted according to a method recommended in international standards. No deviation was reported. Substance ID is adequately specified with isomers composition. Therefore full validation applies.

Reason / purpose for cross-reference:

reference to other study

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

Qualifier:

according to guideline

Guideline:

other: ISO 304-1985 (E)

GLP compliance:

yes (incl. QA statement)

Remarks:

Inspected on 10 July 2012 / Signed on 30 November 2012

Type of method:

ring method

Key result

Surface tension:

58.2 mN/m

Temp.:

20.7 °C

Remarks on result:

other: expected 90% saturated solution

Water (calibration)

Temperature = 20.6 -20.8°C

Sample 1: calibration factor = 1.001 (mean of 6 measurements)

Sample 2: calibration factor = 1.000 (mean of 8 measurements)

Test item

Temperature = 20.7 ± 0.5 ºC

Sample 1: 58.3 mN/m (mean of 5 measurements) = 58.4 mN/m corrected pH = 7.1

Sample 2:

58.1 mN/m (mean of 5 measurements)

= 58.1 mN/m corrected

pH = 7.1

As each (corrected) surface tension value was within 0.5 mN/m of the mean (corrected) value, the mean (corrected) value (58.2 mN/m) was considered to be acceptable as the endpoint of the test.

Conclusions:

According to EU A5 criteria, as the result is below the threshold value of 60 mN/m, the substance is considered to have surface-active potential under the experimental conditions.

Executive summary:

The surface tension of the test substance was measured under GLP according to OECD 115/EU A5 guidelines, ring method, at expected 90% of the saturation solubility. Two replicates were performed, and the mean value was corrected with calibration factor from water.

The surface tension of the test substance is 58.2 mN/m, at 20.7°C.

Description of key information

Surface tension = 58.2 mN/m, at 90% saturation expected (i.e. ca ca 4.47 and 1.68 mg/L for the two major components), and 20.7°C.

According to EU A5 criteria, as the result is below the threshold value of 60 mN/m, the substance is considered to have surface-active potential under the experimental conditions. However, since the structure is not characteristic of a true surfactant, and it is not the intended use of the substance (i.e. not a desired property), this conclusion should be taken with caution.

Key value for chemical safety assessment

Surface tension:

58.2

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EU/ISO method and under GLP, is available. It is considered as a key study, and the result is retained as key value.

Concentration is not specified as actual concentration was not measured, and water solubility is expressed per individual isomer, as considered more relevant for a multiconstituent.