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Physical & Chemical properties

Vapour pressure

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
yes
Remarks:
Results taken by direct measurement not linear regression
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
yes
Remarks:
As above
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: vapour pressure balance
Specific details on test material used for the study:
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: room temperature, in the dark
Key result
Temp.:
25 °C
Vapour pressure:
0.021 Pa
Key result
Temp.:
65 °C
Vapour pressure:
0.65 Pa
Transition / decomposition:
no
Conclusions:
The vapour pressure of the test material was assessed in accordance with OECD Guideline 104 and was determined to be 2.1E-02 Pa at 25°C and 0.65 Pa at 65°C.
Executive summary:

Test Guidance

The vapour pressure was determined using a vapour pressure balance. Testing was conducted using a procedure designed to be

compatible with Method A4 Vapour Pressure of Commissions Regulation (EC) No. 440/2208 of 30 May 2008 and Method 104

of the OECD Guidelines for Testing of Chemicals, 23 March 2006

 

Method

The vapour pressure was determined using a vapour pressure balance, the temperature of the sample was controlled electronically. The mass and temperature reading were recorded automatically as a computer file.

A preliminary run was undertaken, in two runs due to an instrument error, that covered the temperature range 20 to 158°C to provide information for the definitive determinations.

Two definitive sequences of runs were started after the sample of test item had been under vacuum for approximately 87¾ and 215¼ hours for the determinations at 25°C and 65°C respectively. Temperature and pressure readings were taken between 20 to 30 °C and 60 to 70°C both in 1°C steps with a one hour dwell at the lower temperature for direct measurements at 25°C and 65°C respectively.

The study results were taken from direct measurements at 25°C and 65°C and not via linear regression. This approach had no impact on the study outcome.

Result

The vapour pressure was found to be 2.1E- 02 Pa at 25°C and 0.65Pa at 65°C

Description of key information

 The vapour pressure of the test material was assessed in accordance with OECD Guideline 104 and was determined to be 2.1E-02 Pa at 25°C and 0.65 Pa at 65°C.

Key value for chemical safety assessment

Vapour pressure:
0.021 Pa
at the temperature of:
25 °C

Additional information