Supernatant from the crystallisation of L-threonine from the broth filtrate from the fermentative production of L-threonine

Guidance on Safe Use

First-aid measures

Inhalation:

If aerosol or mists are formed:

If necessary: Provide with fresh air.

Skin contact:

Wash off with plenty of water and soap.

Eye contact:

Rinse thoroughly with plenty of water keeping eyelid open.

In case of persistent discomfort: Consult an ophthalmologist.

Ingestion:

Have the mouth rinsed with water.

After absorbing large amounts of substance / In case of discomfort: Supply with medical care.

Most important symptoms and effects, both acute and delayed:

Indication of any immediate medical attention and special treatment needed:

After absorbing large amounts of substance:

Administration of activated charcoal.

Acceleration of gastrointestinal passage.

Fire-fighting measures

Suitable extinguishing media:

The product itself is not flammable; adapt fire-extinguishing measures to surroundings.

Special hazards arising from the substance or mixture:

In specific combustion conditions traces of the following poisonous substances cannot be ruled out:

Carbon monoxide

Carbon dioxide

Hydrocyanic acid

Nitrogen oxides (NOx).

Special protective equipment for fire-fighters:

May be released in case of fire: toxic gases/vapours.

In the event of fire, wear self-contained breathing apparatus.

Advice for firefighters:

Solution is not flammable.

Fire residues and contaminated fire extinguishing water must be disposed of in accordance with local regulations.

Accidental release measures

Personal precautions, protective equipment and emergency procedures:

Smoking, eating and drinking should be prohibited in the application area.

Do not inhale vapours / aerosols.

Avoid contact with skin, eyes and clothing.

Handle in accordance with good industrial hygiene and safety practices.

Environmental precautions:

Do not allow the product into the following compartments:

Surface water

Groundwater.

Methods and material for containment and cleaning up:

Flush away with water.

Suitable binder: vermiculite, sawdust.

Additional advice:

This product presents a slippery hazard on floors.

Avoid formation of aerosol.

Handling and storage

Handling:

Precautions for safe handling:

Wear personal protective equipment.

Avoid contact with eyes.

Avoid contact with skin.

Wash contact areas after handling.

Advice on protection against fire and explosion:

No special precautions required.

Storage:

Conditions for safe storage, including any incompatibilities:

Do not seal containers gas-tight, but keep them closed.

Packages, containers and tanks should regularly be checked by visual observation for any sign of abnormality, e.g. corrosion, exert pressure (bulging), temperature increase etc.

Storage capability limited; dependent on Storage conditions.

Avoid sun rays and frost.

Avoid temperatures above 25 °C.

German storage class:

12 - Non Combustible Liquids.

Storage stability:

Crystallisation of the product is possible at longer storage under 10 °C.

Use of a gas-tight closure involves a risk of bursting.

Transport information

Land transport (UN RTDG/ADR/RID)

Shipping

Special provisions / remarks

Remarks:

Not dangerous according to transport regulations.

Inland waterway transport (UN RTDG/ADN(R))

Shipping

Special provisions / remarks

Remarks:

Not dangerous according to transport regulations.

Marine transport (UN RTDG/IMDG)

Shipping

Special provisions / remarks

Remarks:

Not dangerous according to transport regulations.

Air transport (UN RTDG/ICAO/IATA)

Shipping

Special provisions / remarks

Remarks:

Not dangerous according to transport regulations.

SpecialProvisions

Exposure controls / personal protection

Control parameters:

No substance-specific limiting value being known.

Engineering measures:

Avoid formation of aerosol.

Store in a receptacle equipped with a vent.

Ensure adequate ventilation, especially in confined areas.

If there is the possibility of skin/eye contact, the indicated hand/eye/body protection should be used.

Personal protective equipment:

Respiratory protection:

In the case of dust or aerosol formation use respirator with an approved filter.

Hand protection:

Selection of protective gloves to meet the requirements of specific workplaces.

Suitability for specific workplaces should be clarified with protective glove manufacturers.

Suitable protective gloves: e.g. rubber gloves, PVC gloves

Eye protection:

Protective goggles in case of splash risk recommended.

Skin and body protection:

When handling larger quantities: light protective clothing, disposable protective suit

Hygiene measures:

No eating, drinking, smoking, or snuffing tobacco at work.

Wash face and/or hands before break and end of work.

Environmental exposure controls:

Stability and reactivity

Conditions to avoid:

Avoid temperatures above 25 °C.

Safety notes:

Store in a receptacle equipped with a vent.

At increased temperatures relevant quantities of CO2 can be released.

Provide appropriate exhaust ventilation.

Disposal considerations

Product:

Where possible recycling is preferred to disposal or incineration.

If recycling is not practicable, dispose of in compliance with local regulations.

With respect to local regulations, e.g. dispose of to waste incineration plant or dispose of to biological sewage treatment plant (after neutralisation and after sufficient dilution).