Registration Dossier
Registration Dossier
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EC number: 941-188-2 | CAS number: -
Endpoint summary
Administrative data
Description of key information
The key study for acute oral toxicity reports an LD50 value of >5000 mg/kg in rat (Biolab 1990; rel 2). The acute dermal study reports an LD50 value of 6180mg/kg (Lifestream Laboratories, 1966; rel 2) for Alcohols, C14-15, predominantly linear. Alcohols, C14-15-branched and linear and Alcohols, C14-15 are closely related and free read-across is possible.
Key value for chemical safety assessment
Additional information
The most recent and high reliability information weas assigned as key studies. The data for acute inhalation toxicity was waived on the premise that high reliability data were available via the oral and dermal routes, in accordance with current REACH requirements, Section 5.2 in Annex VIII. Furthermore, based on the information on other alcohols across category, the LC50 for inhalation toxicity is expected to be greater than the substantially saturated vapour concentration.
In addition to the exisiting key studies for acute oral and dermal toxicity, high reliability supporting studies are also available which are in accordance with the key findings.
The presence of branched structures does not appear confer aliphatic alcohols different toxicological properties compared to the Alcohols, C14 -15 linears only substance. Therefore the data is freely read-across between Alcohols, C14 -15 -branched and Alcohols, C14 -15 substances.
In some cases the CAS and chemical identity stated refer to SDA nomenclature for this substance. In REACH substance identification it is necessary to be more specific as to the chain lengths present. Full details may be found in the CSR
Justification for classification or non-classification
Acute toxicity tests do not indicate any potential hazard for acute, dermal or inhalation toxicity for Alcohols, C14 -15 -branched. Tests on similar substances included in this category are also supportive of these results; which do not warrant classification for any acute toxicity endpoint under DSD or GHS criteria. The substance is therefore not classified for acute toxicity in accordance with EC regulation 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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