Reaction mass of N-[(5-methyl-1H-pyrazol-1-yl)methyl]acetamide AND N-[(3-methyl-1H-pyrazol-1-yl)methyl]acetamide

Oxidising properties

Link to relevant study record(s)

Reference

Endpoint:

oxidising solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2009-01-13 - 2009-02-10

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: The GLP study was conducted according to an internationally accepted guideline. All study parameters are based on the specific guideline.

Qualifier:

according to guideline

Guideline:

EU Method A.17 (Oxidising Properties (Solids))

Deviations:

yes

Remarks:

Instead of five different mixtures reference item/cellulose, only three mixtures (60 / 70 / 80% reference item) were prepared and tested.

GLP compliance:

yes (incl. QA statement)

Contact with:

powdered cellulose

Sample tested:

test mixture (not specified)

Remarks:

migrated information

Parameter:

maximum burning rate

Result:

393 s

Sample tested:

reference mixture (not specified)

Remarks:

migrated information

Parameter:

maximum burning rate

Result:

229 s

%Ba(N03)2	Burning Time (s)	Burning Rate (mm/s)
60	229	0.87
70	206	0.97
80	225	0.89
In the following table, the measured data of the test item mixtures are presented.
Table 7.3-d: Burning Rate of Test Item Mixtures
%Test Item	Burning Time (s)	Burning Rate (mm/s)
10	192	1.04
20	195	1.02
30	248	0.81
40	194	1.03
50	113	1.77
60	139	1.44
70	147	1.36
80	177	1.13
90	393	0.51

The mixture with 50 % test item shows the highest burning rate. All mixtures with test item showed no vigorous reaction. Only the surface of the pile burned, below, a brown layer was found; beneath this layer, the unchanged mixture was visible. Melting of the test item was observed. It was suspected, that a false positive result was obtained due to the faster propagation of the flame along the powder train with the melted test item.

7.3.5 Additional Experiment under Air

In order to exclude a false positive result, the test was repeated in an atmosphere with less than 2% 0₂(under argon). In this experiment, ignition was attempted using an electric wire.

No ignition with propagating flame was observed. Only in direct contact with the electric wire, melting of the test item and smouldering of the mixture was observed, but ignition did not propagate further. Therefore, the study was terminated.

Interpretation of results:

other: no oxidising properties

Remarks:

Migrated information

Conclusions:

The oxidising properties of N-[(3(5)-Methyl-1 H-pyrazol-1 -yl)-methyl]acetamide was determined according to EU Method A.17 (Oxidising Properties (Solids).The test item should be considered as not oxidising.
Although the burning rate of the test item mixtures were higher than the burning rate of the reference item mixtures, no vigorous reaction was observed. In inert atmosphere, no propagating flame was seen. Therefore, the result from the main study was considered as false positive. Taking into account the molecular structure of the test item, oxidising properties are not probable, either.
Therefore, the test item is considered to have no oxidising properties.

Executive summary:

The oxidising properties of N-[(3(5)-Methyl-1 H-pyrazol-1 -yl)-methyl]acetamide was determined according to EU Method A.17 (Oxidising Properties (Solids).The test item should be considered as not oxidising. Although the burning rate of the test item mixtures were higher than the burning rate of the reference item mixtures, no vigorous reaction was observed. In inert atmosphere, no propagating flame was seen. Therefore, the result from the main study was considered as false positive. Taking into account the molecular structure of the test item, oxidising properties are not probable, either. Therefore, the test item is considered to have no oxidising properties.

Description of key information

The oxidising properties of N-[(3(5)-Methyl-1 H-pyrazol-1 -yl)-methyl]acetamide was determined according to EU Method A.17 (Oxidising Properties (Solids).The test item should be considered as not oxidising. Although the burning rate of the test item mixtures were higher than the burning rate of the reference item mixtures, no vigorous reaction was observed. In inert atmosphere, no propagating flame was seen. Therefore, the result from the main study was considered as false positive. Taking into account the molecular structure of the test item, oxidising properties are not probable, either. Therefore, the test item is considered to have no oxidising properties.

Key value for chemical safety assessment

Oxidising properties:

no

Additional information

Therefore, the test item is considered to have no oxidising properties.

Justification for classification or non-classification

No classification of N-[(3(5)-Methyl-1 H-pyrazol-1 -yl)-methyl]acetamide is required.