Reaction mass of 1,4-dichlorobut-2-ene; 3,4-dichlorobut-1-ene

Short-term toxicity to fish

Administrative data

Endpoint:

short-term toxicity to fish

Type of information:

other: Migrated dataset

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Adopted according to OECD SIDS. The original source is not available and has not been reviewed.

Data source

Reference

Reference 1

Reference Type:

secondary source

Title:

1,4-Dichlorobut-2-ene - CAS No: 764-41-0

Author:

OECD SIDS

Year:

2006

Bibliographic source:

SIDS Initial Assessment Report for 22th SIAM, UNEP Publications

Reference 2

Reference Type:

review article or handbook

Title:

Handbook of Environmental Data on Organic Chemicals (3rd ed.)

Author:

Verschueren (as cited in OECD SIDS)

Year:

1996

Bibliographic source:

Van Nostrand Reinhold, New York

Reference 3

Reference Type:

publication

Title:

Joint Toxicity of Mixtures of Groups of Organic Aquatic Pollutants to the Guppy (Poecilia reticulata).

Author:

Hermens, J, Busser, F. Leeuwangh, P., Musch, A. (as cited in OECD SIDS)

Year:

1985

Bibliographic source:

Ecotoxicology and Environmental Safety 9, 321-326

Reference 4

Reference Type:

publication

Title:

Quantitative structure-activity relationships and mixture toxicity of organic chemicals in Photobacterium phosphoreum. The microtox Test.

Author:

Hermens, J, Busser, F. Leeuwangh, P., Musch, A. (as cited in OECD SIDS)

Year:

1985

Bibliographic source:

Ecotoxicology and Environmental Safety 9, 17-25

Reference 5

Reference Type:

publication

Title:

Theoretical descriptors for the correlation of aquatic quantitative structure-toxicity relationships.

Author:

Katritzky A R, Tatham DB, Maran U (as cited in OECD SIDS)

Year:

2001

Bibliographic source:

J. Chem. Inf. Sci. 41 (5), 1162-1176

Materials and methods

Principles of method if other than guideline:

other: test procedure according to Koenemann H (1981). Toxicology 19, 209-221.

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

trans-2,3-dichlorobut-2-ene

EC Number:

203-779-7

EC Name:

trans-2,3-dichlorobut-2-ene

Cas Number:

110-57-6

IUPAC Name:

2,3-dichlorobut-2-ene

Details on test material:

- Name of test material (as cited in study report): trans-1,4-dichlorobut-2-ene
- purity > 95 %

Sampling and analysis

Analytical monitoring:

yes

Test organisms

Test organisms (species):

Poecilia reticulata

Study design

Test type:

semi-static

Results and discussion

Effect concentrations

Duration:

14 d

Dose descriptor:

LC50

Effect conc.:

0.086 mg/L

Any other information on results incl. tables

Sublethal observations / clinical signs:

RS-Freetext:
LC50 values were calculated according to Litchfield and Wilcoxon ((1949).  A simplified method of evaluating dose-effect experiments. J. Pharmacol.  Exp. Ther. 96, 99-113, ) or in case of a steep concentration-effect  relationship by estimating using a log/probit plot.
Experimentally determined log LC50 value (14d): -0.16 µmol/l  (corresponding to LC50 (14d): 0.0864 mg/l)