6-fluoro-3-(piperidin-4-yl)-1,2-benzoxazole hydrochloride

Explosiveness

Administrative data

Endpoint:

explosive properties of explosives

Type of information:

experimental study

Adequacy of study:

key study

Study period:

11 August 2017 - 25 September 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2017

Report date:

2017

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method A.14 (Explosive properties)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

other: EC 440/2008

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

6-FLUORO-3-(PIPERIDIN-4-YL)-1,2-BENZOXAZOLE HYDROCHLORIDE

EC Number:

700-303-4

Cas Number:

84163-13-3

Molecular formula:

C12H13FN2O.HCl

IUPAC Name:

6-FLUORO-3-(PIPERIDIN-4-YL)-1,2-BENZOXAZOLE HYDROCHLORIDE

Test material form:

solid: particulate/powder

Specific details on test material used for the study:

- Batch n°: I16KC4116
- Analytical purity: not reported
- Expiration date: not reported
- Storage condition: at room temperature

Results and discussion

Results of test series for explosives

Results of test series for explosives 1

Test series:

UN Test series 3

Method:

UN Test 3 (a) (ii): BAM Fallhammer

Parameter:

limiting impact energy (J)

Result:

result is considered "-" (negative)

Remarks on result:

other: See "Remarks"

Remarks:

The test sample was observed to exhibit no reaction at 40 J, which is considered to be negative

Results of test series for explosives 2

Test series:

UN Test series 3

Method:

UN Test 3 (b) (i): BAM friction apparatus

Parameter:

limiting load (N)

Result:

result is considered "-" (negative)

Remarks on result:

other: See "Remarks"

Remarks:

The test sample was observed to exhibit no reaction at 360 N which is a negative result

Results of test series for explosives 3

Test series:

UN Test series 2

Method:

UN Test 2 (b): Koenen test

Parameter:

limiting diameter (mm)

Result:

result is considered "-" (negative)

Remarks on result:

other: See "Remarks"

Remarks:

The sample did not exhibit an explosion during any of the tests hence it is considered negative

Any other information on results incl. tables

- The results for BAM Fallhammer test were as follows:

Mass (kg)	Height (m)	Test number and result						Comments
		1	2	3	4	5	6
10	0.4	40	x	x	x	x	x	No reaction observed

x - denotes no reaction or decomposition (change in colour).

The test sample was observed to exhibit no reaction at 40 J. The test result is therefore considered Negative (-) (according to the EC Classification, Packaging & Labelling of Dangerous Substances in the European Union Part 2, Testing Methods, Jan 97).

- The results for BAM friction test were as follows:

Mass (kg)	Height (m)	Test number and result						Comments
		1	2	3	4	5	6
8.34	360	x	x	x	x	x	x	No reaction observed

x - denotes no reaction or decomposition (change in colour)

The test sample was observed to exhibit no reaction at 360 N. The test result is therefore considered Negative (-) (according to the EC Classification, Packaging & Labelling of Dangerous Substances in the European Union Part 2, Testing Methods, Jan 97).

- The results for Koenen tube test were as follows:

Mass of Sample (g)	Orifice Diameter (mm)	Time to First Ignition (s)	Explosion
22.2	6	18	x
22.2	6	21	x
22.2	6	19	x
22.2	2	45	x
22.2	2	48	x
22.2	2	54	x

x - denotes fewer than 3 fragments.

The sample did not exhibit an explosion during any of the tests. The test result is therefore considered Negative.

Applicant's summary and conclusion

Interpretation of results:

GHS criteria not met

Conclusions:

The results of all the three tests namely, BAM Fallhammer, BAM Friction and Koenen Tube were negative which is sufficient to conclude that the test item is not explosive.