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Diss Factsheets
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EC number: 916-899-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Dissociation constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- dissociation constant
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Remarks:
- Method no.: SOP 00288 Version 1 This SOP corresponds to OECD Guidelines for Testing of Chemicals, Section 1 – Physical-Chemical Properties No: 112 “Dissociation Constants in Water”.
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 112 (Dissociation Constants in Water)
- Version / remarks:
- Method no.: SOP 00288 Version 1
This SOP corresponds to OECD Guidelines for Testing of Chemicals, Section 1 – Physical-Chemical Properties No: 112 “Dissociation Constants in Water”. - GLP compliance:
- yes
- Dissociating properties:
- yes
- pKa:
- 8.2
- Temp.:
- 20 °C
- Conclusions:
- Bayscript Blaukomponente TEA-Salz has a pKa value of 8.2 at 20°C.
- Executive summary:
The dissociation constant of Bayscript Blaukomponente TEA-Salz was investigated in accordance with the Guidline OECD 121. The determination of the dissociation constant was performed by titration. A defined amount of hydrochloric acid (0.1 mol/L) was added to convert the molecule completely into the acid form (nonionic form) and the solution was titrated with sodium hydroxide solution (0.1 mol/L). From the pH value of complete neutralization of the acid, the pH of half the neutralization (= pKa value) was calculated by the software of the titroprocessor. A pKa value of 8.2 was determined at 20°C by potentiometric titration (Currenta 2016).
As the UVCB substance Bayscript Blaukomponente TEA is a complex mixture composed of three main components and unknown impurities, no clear conclusion on dissociation state can be received. Effects of impurities and the ammonium counterion on the measured result can be assumed. In accordance with ECHA Guidance R.7a, for complex mixtures (e.g. UVCBs) containing ionisable components the assessment of pKa is clearly complicated. Estimation of the representative constituent’s pKa values, if applicable, should be considered.
Reference
Description of key information
The dissociation constant of Bayscripot Blaukomponente TEA-Salz was investigated in accordance with the Guidline OECD 121. A pKa value of 8.2 was determined at 20°C by potentiometric titration (Currenta 2016).
Key value for chemical safety assessment
- pKa at 20°C:
- 8.2
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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