Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 600-813-6 | CAS number: 1072-68-0
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Depending on local conditions and existing concentrations, disturbances in the biodegradation process of activated sludge are possible. The nitrification performance of activated sludge during the elimination via sewage treatment plants may be interfered.
Key value for chemical safety assessment
Additional information
In a GLP short-term respiration test according to OECD 209 conducted with 1,4-Dimethyl-1H-pyrazole (CAS 1072-68-0) an EC10 (180 min) of 1.1 mg/L (3h EC50 = 10 mg/L) was obtained for nitrification inhibition (3h values of 1.9 mg/L (EC10) and 110 mg/L (EC50) were determined for total oxygen uptake). The test was performed using domestic activated sludge.
The 3h EC10 value for nitrification inhibition (1.1 mg/L) was used for the derivation of the PNEC-STP.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
