5-(Acetyl-(3-(acetyl-(3,5-bis(2,3-dihydroxypropylcarbamoyl)-2,4,6-triiodophenyl)amino)-2- hydroxypropyl)amino)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide; 5,5'-((2-Hydroxytrimethylene)bis(acetylimino))bis(N,N'-bis(2,3-dihydroxypropyl)-2,4,6- triiodoisophthalamide);

Density

Administrative data

Endpoint:

density

Remarks:

density

Type of information:

experimental study

Adequacy of study:

weight of evidence

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: This study was conducted in accordance with Good Laboratory Practices and Good Manufacturing Practices.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1992

Materials and methods

Test guideline

Guideline:

other: Technical Assistance Document 3.07, Environmental Assessment Technical Assistance Handbook issued by Food and Drug Administration, 1987

Principles of method if other than guideline:

The density of the Iodixanol was determined by wide-mouth pycnometer technique. This technique consist of placing Iodixanol in a containing of which the capacity is accurately known and which may be completely filled with liquid. The difference in weight when filled and when empty , along with the known volume of liquid, gives the density. For this experiment, hexane (20C) was used as the immersion liquid since Iodixanol is freely soluble in water.

GLP compliance:

yes

Type of method:

pycnometer method

Test material

Reference

Name:

Unnamed

Type:

Constituent

Results and discussion

Density

Key result

Type:

density

Density:

2.08 g/cm³

Temp.:

20 °C