Registration Dossier
Registration Dossier
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EC number: 926-197-1 | CAS number: -
Vapour pressure
Administrative data
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 24 August 2015-17 November 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP-compliant study in accordance with EC A.4 and OECD 104.
Data source
Referenceopen allclose all
- Reference Type:
- other: study amendment
- Title:
- Unnamed
- Year:
- 2 021
- Report date:
- 2021
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2015
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- (2009)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- (2006)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7950 (Vapor Pressure)
- Version / remarks:
- (1996)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- other: Effusion method: isothermal thermogravimetry
Test material
- Reference substance name:
- 5-[(S)-4-Carboxy-4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-butyrylamino]-2-nitro-benzoic acid
- EC Number:
- 926-197-1
- Cas Number:
- 2561176-48-3
- Molecular formula:
- C20 H15 N3 O9
- IUPAC Name:
- 5-[(S)-4-Carboxy-4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-butyrylamino]-2-nitro-benzoic acid
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- - Name (as cited in study report): P-Glupa-C
- Appearance: yellow powder
- Storage conditions: at room temperature
Constituent 1
Results and discussion
Vapour pressureopen allclose all
- Temp.:
- 25 °C
- Vapour pressure:
- < 7 other: E-03 Pa
- Remarks on result:
- other: (<5.3E-05 mm Hg)
- Temp.:
- 20 °C
- Vapour pressure:
- < 1.5 other: E-03 Pa
- Remarks on result:
- other: (<1.1E-05 mm Hg)
Any other information on results incl. tables
The weight losses of the test substance at 110°C, 120°C, 130°C and 140°C were lower than the weight losses of hexachlorobenzene at the same temperatures. From this it was concluded that vapour pressure of the substance at 20°C (25°C) is lower than the vapour pressure of hexachlorobenzene at 20°C (25°C).
Applicant's summary and conclusion
- Conclusions:
- In a GLP-compliant study in accordance with EC A.4, OECD 104 and EPA OPPTS 830.7950 using the isothermal thermogravimetric effusion method, the vapour pressure of the substance at 25°C has been determined as < 7.06E-03 Pa. The vapour pressure of the substance at 20°C has been determined as < 1.5E-03 Pa.
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