Registration Dossier
Registration Dossier
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EC number: 602-927-1 | CAS number: 123312-89-0
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 20 May 1992 to 12 Jun. 1992
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: SOP 433.1.209
- GLP compliance:
- yes
- Other quality assurance:
- other: EPA Good Laboratory Practice Standards; U.S.A., 40 CFR part 160; August 17, 1989
- Medium:
- ethanol
- Solubility:
- 2 400 mg/L
- Temp.:
- 25 °C
- Remarks on result:
- other: Batch No. AMS 522/101
- Medium:
- acetone
- Solubility:
- 940 mg/L
- Temp.:
- 25 °C
- Remarks on result:
- other: Batch No. AMS 522/101
- Medium:
- toluene
- Solubility:
- 34 mg/L
- Temp.:
- 25 °C
- Remarks on result:
- other: Batch No. AMS 522/101
- Medium:
- n-octanol
- Solubility:
- 450 mg/L
- Temp.:
- 25 °C
- Remarks on result:
- other: Batch No. AMS 522/101
- Medium:
- other: n-hexane
- Solubility:
- < 1 mg/L
- Temp.:
- 25 °C
- Remarks on result:
- other: Batch No. AMS 522/101
- Medium:
- ethyl acetate
- Solubility:
- 260 mg/L
- Temp.:
- 25 °C
- Remarks on result:
- other: Batch No. AMS 522/102
- Medium:
- other: dichloromethane
- Solubility:
- 1 200 mg/L
- Temp.:
- 25 °C
- Remarks on result:
- other: Batch No. AMS 522/102
- Test substance stable:
- not determined
- Executive summary:
The test was performed in compliance with GLP. The solubility of test substance in different organic solvents is presented below:
ethanol: 2400 mg/L
acetone: 940 mg/L
toluene: 34 mg/L
n-octanol: 450 mg/L
n-hexane: <1 mg/L
ethyl acetate: 260 mg/L
dichloromethane: 1200 mg/L
Reference
Description of key information
The test was performed in compliance with GLP, (Stulz, 1993). The solubility of test substance in different organic solvents is presented below:
ethanol: 2400 mg/L
acetone: 940 mg/L
toluene: 34 mg/L
n-octanol: 450 mg/L
n-hexane: <1 mg/L
ethyl acetate: 260 mg/L
dichloromethane: 1200 mg/L.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
