Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Explosiveness

Currently viewing:

Administrative data

Endpoint:
explosive properties of explosives
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Information inssufficient for assessment. No data on substance purity.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.14 (Explosive properties)
Deviations:
yes
Remarks:
1)The weight of the falling hammer is 5 kg and dropped from 0.8 m, however, the energy applied is the same as in the guideline, 40 J or 40 Nm. 2) In contrast to the EC guideline aluminium foil is used to pack the substance. 3) Ten tests are performed.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
(1R,4R,6S,7Z,15R,17R)-17-({7-methoxy-8-methyl-2-[4-(propan-2-yl)-1,3-thiazol-2-yl]quinolin-4-yl}oxy)-13-methyl-2,14-dioxo-3,13-diazatricyclo[13.3.0.0^{4,6}]octadec-7-ene-4-carboxylic acid
EC Number:
618-844-9
Cas Number:
923604-58-4
Molecular formula:
C35H42N4O6S
IUPAC Name:
(1R,4R,6S,7Z,15R,17R)-17-({7-methoxy-8-methyl-2-[4-(propan-2-yl)-1,3-thiazol-2-yl]quinolin-4-yl}oxy)-13-methyl-2,14-dioxo-3,13-diazatricyclo[13.3.0.0^{4,6}]octadec-7-ene-4-carboxylic acid
Test material form:
solid: particulate/powder
Details on test material:
- Name of test material (as cited in study report): JNJ-38940642-AAA (T003010)
- Physical state: solid
- Appearance: white powder

Results and discussion

Small-scale preliminary tests
Parameter:
sensitiveness to impact: impact energy (J)
Remarks on result:
negative (not further specified)
Remarks:
If all tests according to Lütolf method are negative, powder can be considered not shock sensitive as reference substance meta-dinitrobenzene is not shock sensitive in similar conditions (although not tested simultaneously in this study).

Any other information on results incl. tables

10 times negative. Not shock sensitive (sensitivity> 39.2 Nm)

Applicant's summary and conclusion

Conclusions:
The test substance is not shock sensitive.