Registration Dossier
Registration Dossier
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EC number: 603-689-1 | CAS number: 132961-05-8
Auto flammability
Administrative data
- Endpoint:
- relative self-ignition temperature (solids)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1991-10-22 to 1991-11-05
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 991
- Report date:
- 1991
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.16 (Relative Self-Ignition Temperature for Solids)
- Deviations:
- yes
- Remarks:
- A heating rate of 0.6 °C/min is used instead of 0.5 °C/min due to the technical restriction of the apparatus used.
- Principles of method if other than guideline:
- Modifications to the EU A.16 Method: A heating rate of 0.6 deg C/min is used instead of 0.5 deg C/min due to the technical restriction of the apparatus used. A special temperature-programmed oven, known as Grewer oven and comercially available at Kuhner AG, Switzerland, is used. The oven is equipped with thermocopules and may contain 6 cylindric open top wire baskets with 0.2 mm openings. The temperature of the oven and of the samples can be monitored. One wire basket is fillde with the substance, a second wire basket with graphite as a temperature reference.
- GLP compliance:
- yes
Test material
- Reference substance name:
- 3-(2-{4-[(Z)-(2,4-DIFLUOROPHENYL)(HYDROXYIMINO)METHYL]PIPERIDIN-1-YL}ETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE
- EC Number:
- 603-689-1
- Cas Number:
- 132961-05-8
- Molecular formula:
- C23H28F2N4O2
- IUPAC Name:
- 3-(2-{4-[(Z)-(2,4-DIFLUOROPHENYL)(HYDROXYIMINO)METHYL]PIPERIDIN-1-YL}ETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE
- Test material form:
- solid: particulate/powder
Constituent 1
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): T001624
- Physical state: powder
- Analytical purity: >97% (HPLC)
- Impurities (identity and concentrations): sum impiurities: 3% maximum
- Lot/batch No.: 00096264
- Storage condition of test material: the sample was stored at room temperature
Results and discussion
Relative self-ignition temperature (solids)
- Key result
- Remarks on result:
- no self-ignition observed up to the melting point
Any other information on results incl. tables
-The sample is heated from room temperature (about 20 °C) to about 215 °C. The sample shows endothermic melting behaviour in the range of 170 to 180 °C.
After the endothermic signal the sample temperature slightly surpass the reference temperature but the sample temperature does not reach 400°C.
-The substance T001624 is not auto-flammable up to the melting point
Applicant's summary and conclusion
- Conclusions:
- In conclusion, the tested substance T001624 is not auto-flammable up to the melting point.
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