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EC number: 500-344-6 | CAS number: 157627-94-6 1 - 2.5 moles ethoxylated
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 02 Sep - 01 Oct 2004
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): activated sludge from the municipal wastewater treatment plant Breisgauer Bucht was used as inoculum with a concentration corresponding to 30 mg dry solids per litre. The treatment plant clarifies predominantly domestic wastewater of the region Freiburg and has a capacity of 600000 inhabitant equivalents.
- Preparation of inoculum for exposure: the activated sludge was washed twice by settling the sludge, decanting the supernatant and resuspending the sludge in aerated tap water.
- Concentration of sludge: to 1484.8 mL mineral medium 15.2 mL activated sludge was added, corresponding to 30 mg/L dry solids. - Duration of test (contact time):
- 28 d
- Initial conc.:
- 20 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium: Solution A: KH2PO4: 8.50 g, K2HPO4: 21.75 g, Na2HPO4 x 2H2O: 33.40 g, NH4Cl: 0.50 g; Solution B: CaCl2 x 2H2O: 36.4 g; Solution C: MgSO4 x 7H2O: 22.50 g; Solution D: FeCl3 x 6H2O: 0.25 g. For preparation of the mineral medium 10 mL of solution A is mixed with 800 mL demineralised water, 1 mL of solutions B, C and D are added and made up to 1 litre each.
- Test temperature: 21.0 °C - 22.1 °C
- Aeration of dilution water: aeration with CO2-free air at a rate of 50 - 100 mL/min
- Suspended solids concentration: dry solids of the acitvated sludge was determined as 2.96 g/L by weight measurements after 2 h drying at 105 °C (mean of triplicate measurements)
TEST SYSTEM
- Culturing apparatus: gas wash bottles (2000 mL volume) with lateral connecting pieces for butyl rubber septums were used as reactors.
- Number of culture flasks/concentration: 3
- Measuring equipment:
- Details of trap for CO2 and volatile organics if used: CO2-absorption medium: 72 g NaOH were dissolved in 9000 mL deionised water in closed recipients (0.2 M NaOH).
- Other: the CO2-free air production system consists of an air compressor, two 1000 mL gas wash bottles filled with dry soda lime, followed by one bottle filled with 0.1 M NaOH. At the end of the system was one gas wash bottle filled with demineralised water, followed by an empty one to catch any drops of condensation water. A colour range of the soda lime from white to blue indicates, that CO2 absorption capacity is depeted. The CO2-free air is passed on to an air distributer with two imput and 22 output channels and through PE-tubes.
SAMPLING
- Sampling frequency: 4, 7, 11, 14, 21 and 28 days
- Sampling method: sampling was performed through the lateral connecting pieces through the butyl rubber septum using 5 mL PE syrings.
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes - 3 replicates
- Toxicity control: yes - 1 replicate containing test item and reference compound - Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 78.4 - 100.9
- Sampling time:
- 28 d
- Results with reference substance:
- The reference compound reached the pass levels for ready biodegradability within 7 days
- Interpretation of results:
- readily biodegradable
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 04 Jun - 22 Jul 1993
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-A (Determination of the "Ready" Biodegradability - Dissolved Organic Carbon (DOC) Die-Away Test)
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): sewage plant: Marl-Ost
- Preparation of inoculum for exposure: centrifugation at 3000 rpm for 15 min. The supernatant was discarded and the sludge resuspended with mineral medium. After another centrifugation step 15 min at 3000 rpm, the sludge was resuspended.
- Concentration of sludge: 25.2 mg/L
- Water filtered: yes - Duration of test (contact time):
- 28 d
- Initial conc.:
- 10.5 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- TEST CONDITIONS
- Composition of medium: solution A: 8.5 g KH2PO4, 21.75 g K2HPO4, 33.3 g NaHPO4 x 2 H2O and 20.0 g (NH4)Cl; solution B: 22.5 g MgSO4 x 7 H2O; solution C: 27.5 g CaCl2; solution D: 0.25 g FeCl3 x 6 H2O
- Test temperature: 20.0 °C - 22.2 °C
- Continuous darkness: yes
SAMPLING
- Sampling frequency: 0, 7, 14, 21, 27 and 28 days
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
- Toxicity control: yes - Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (DOC removal)
- Value:
- 100
- Sampling time:
- 28 d
- Results with reference substance:
- DOC removal: 100% after 28 days
- Interpretation of results:
- readily biodegradable
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Please refer to the Category Approach Justification provided in Section 13
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- GLP compliance:
- yes
- Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 78.4 - 100.9
- Sampling time:
- 28 d
- Remarks on result:
- other:
- Remarks:
- Source, key, 1187742-72-8, 2004
- Results with reference substance:
- The reference compound reached the pass levels for ready biodegradability within 7 days
- Interpretation of results:
- readily biodegradable
Referenceopen allclose all
|
% of ThCO2 |
|||||||
Day |
0 |
4 |
7 |
11 |
14 |
21 |
28 |
28 (after acidification) |
Test substance |
0 |
59.1 |
74.8 |
89.8 |
99.4 |
98.5 |
95.6 |
100.7 |
|
% DOC-removal after x days |
|||||
Day |
0 |
7 |
14 |
21 |
27 |
28 |
Test substance |
0 |
95 |
100 |
98 |
101 |
100 |
|
% of ThCO2 |
|||||||
Day |
0 |
4 |
7 |
11 |
14 |
21 |
28 |
28 (after acidification) |
Test substance |
0 |
59.1 |
74.8 |
89.8 |
99.4 |
98.5 |
95.6 |
100.7 |
Description of key information
Readily biodegradable: 78-100% (ThCO2) in 28 days (OECD 301B)
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Comparing all available biodegradation studies, the members of the AES category can generally be considered as readily biodegradable.
Since no biodegradability tests are available for AES (C12-14, 1-2.5 EO) TEA (CAS 157627-94-6), a read-across approach from the two structurally similar substances AES (C12-14, 1-2.5EO) MIPA (CAS 1187742-72-8) and AES (C12-14, 1-2.5EO) Na (CAS 68891-38-3) was applied.
Both studies were conducted with non-adapted domestic sludge under GLP conditions. The test with AES (C12-14, 1-2.5EO) MIPA (CAS 1187742-72-8) was performed according to OECD guideline 301B (Sasol, 2004). After 28 days a biodegradation rate between 78 - 100% (CO2 evolution) was reported for the MIPA salt.
The test with AES (C12-14, 1-2.5EO) Na (CAS 68891-38-3) was performed according to EU-guidelines (C.4-A) (Sasol, 1993a). This test shows a biodegradation rate of 100% (DOC removal) after 28 days.
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