Registration Dossier
Registration Dossier
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EC number: 430-610-6 | CAS number: 226996-19-6
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
- Year:
- 2 006
- Report date:
- 2006
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 202
- GLP compliance:
- yes
Test material
Constituent 1
Test solutions
- Details on test solutions:
- Identity and concentration of auxiliary solvent for dispersal: - no auxiliary solvent used
- the organic ligand of TN-105 was identified as the only
dissolved residue in water
- test solutions were prepared by stirring the nominal
amounts of test item in 1 L ISO water (200 r.p.m. for
48 hrs at 20 °C) and filtering the eluate by using a
0.22 µm filter (Millipore MCE-MF, cellulose nitrate and
acetyl cellulose, # GSWP04700)
- static test
Test organisms
- Test organisms (species):
- other aquatic crustacea: DM
Test conditions
- Hardness:
- 200 mg CaCO3/L
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 24 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 4.207 mg/L
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 3 mg/L
- Duration:
- 48 h
- Dose descriptor:
- EC100
- Effect conc.:
- > 4.207 mg/L
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.305 mg/L
Applicant's summary and conclusion
- Conclusions:
- TN-105 was tested at nominal concentrations of 12.5, 25, 50, 100 and 200 mg/l (static conditions). The EC50 based on normal concentrations was determined to be 177 mg TN-105/l.
Note: The organic ligand of TN-105 only is dissolved in water (1-2% at 100-200 mg/l).
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