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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
3 March 1997 - 10 April 1997
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes
Type of method:
effusion method: vapour pressure balance
Specific details on test material used for the study:
Name: Molyvan® 855 (Oil-Free)
Description: Dark brown paste
Storage conditions: Room temperature in the dark
Temp.:
25 °C
Vapour pressure:
<= 0 Pa

No statistical analyses were performed because the balance readings were too low and variable for a line of best fit to have any meaning. Instead it was considered more appropriate to impose a regression slope on a chosen data point to provide an estimate of the maximum value for the vapour pressure at 25 deg. C.

Run 3 was chosen because the sample had been under vacuum for the longest period prior to this run so degassing would have been most complete. The reading at 85 deg. C (358.15K) was chosen because this is the data point which gives the highest estimated vapour pressure at any given temperature when a slope of -1500 K is imposed upon it.

The value of -1500 K is an in-house value and is the shallowest slope observed whilst determining the vapour pressure on a wide range of samples using the vapour pressure balance method. Extrapolation to 25 deg. C gave a vapour pressure of 4.127x10^-4 Pa which has been taken as a maximum value for the test item.

The test material did not change in appearance under the conditions used in determination, however it did dry out.

Conclusions:
The vapour pressure of the test item has been determined to be less than 4.2E-04 Pa at 25 deg. C.
Executive summary:

In an EU Method A.4 109 study, conducted according to GLP, the vapour pressure of the test item is less than 4.2E-04 Pa at 25 deg.C (SafePharm Laboratories Limited, 1997)

Description of key information

The vapour pressure of the test item has been determined to be less than 4.2E-04 Pa at 25 deg C.

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
25 °C

Additional information

In an EU Method A.4 109 study, conducted according to GLP, the vapour pressure of the test item is less than 4.2E-04 Pa at 25 deg.C (SafePharm Laboratories Limited, 1997).