Registration Dossier
Registration Dossier
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EC number: 405-290-6 | CAS number: 12036-37-2
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Description of key information
In accordance with REACH Annex XI it is considered appropriate to omit the Screening for reproductive/developmental toxicity study due to the substance's apparent lack of bioavailability and thus testing does not appear scientifically necessary. The substance displayed no signs of toxicity in acute toxicity tests via the oral route at levels of 5000mg/kg bw or the inhalation route at the highest achievable concentration and has been shown to be unreactive, insoluble in the various texts conducted and there is no evidence of toxicity in a 28 day "limit test" via the oral route.
Link to relevant study records
- Endpoint:
- toxicity to reproduction
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Reproductive effects observed:
- not specified
Reference
Effect on fertility: via oral route
- Endpoint conclusion:
- no study available
Effect on fertility: via inhalation route
- Endpoint conclusion:
- no study available
Effect on fertility: via dermal route
- Endpoint conclusion:
- no study available
Effects on developmental toxicity
Description of key information
In accordance with REACH Annex XI it is considered appropriate to omit the Screening for reproductive/developmental toxicity study due to the substance's apparent lack of bioavailability and thus testing does not appear scientifically necessary. The substance displayed no signs of toxicity in acute toxicity tests via the oral route at levels of 5000mg/kg bw or the inhalation route at the highest achievable concentration and has been shown to be unreactive, insoluble in the various texts conducted and there is no evidence of toxicity in a 28 day "limit test" via the oral route.
Link to relevant study records
- Endpoint:
- developmental toxicity
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Abnormalities:
- not specified
- Developmental effects observed:
- not specified
Reference
Effect on developmental toxicity: via oral route
- Endpoint conclusion:
- no study available
Effect on developmental toxicity: via inhalation route
- Endpoint conclusion:
- no study available
Effect on developmental toxicity: via dermal route
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
