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EC number: 303-773-5 | CAS number: 94213-67-9
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Daphnia 48-h EC50: 2.6 mg/L
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 2.6 mg/L
Additional information
In the Klimisch 1 GLP study from Kimmel (2013) the acute toxicity of Sulfosuccinic (FA C16-18/18:1)E, Na/NH4 on Daphnia magna was determined in an 48 hour static test according to OECD 202 and EU method C.2. The test was performed with concentrations of control and 0.625, 1.25, 2.5, 5.0 and 10 mg/L, The measured concentrations of test item in the test media of the biologically relevant test concentrations of 2.5 to 10 mg/L were between 82 and 87% of the nominal values at the start of the test and between 62 and 66% at the end of the test. Thus, the correct dosage of the test item was confirmed. The test item concentration declined in the test media over the test period of 48 hours. The biological results were related to the mean measured test item concentrations calculated as the geometric means of the concentrations measured at the start and end of the test, i.e. 1.8, 3.7 and 7.4 mg/L for nominal 2.5, 5 and 10 mg/L respectively. Four replicates with 5 daphnids each were set up. After 48 hours 0, 0, 0, 0, 100 and 100 % immobilization was observed in the control and at test concentrations of nominal ontrol and 0.625, 1.25, 2.5, 5.0 and 10 mg/L, respectively. The data were evaluated based on mean measured concentrations. The EC50 is 2.6 mg/L.
Read across is made from CAS 147993-66 -6 (source) to the substance related to CAS 94213-67-9 (target). Both substances have a similar C-chain distribution. Assessment factors are not needed.
The results are considered relevant and reliable for the risk assessment.
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