Registration Dossier
Registration Dossier
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EC number: 295-394-6 | CAS number: 92045-12-0
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
Read across justification
Several criteria justify the use of the read across approach to fill data gaps for foots oils using other lubricant base oil analogs. Primarily the basis for the read-across is the similar physical chemical properties shared by the foots oils and other lubricant base oils.
Short-term toxicity to aquatic invertebrates has been filled by read-across of measured data from other lubricant base oils. It is supported in a weight of evidence approach by a calculated value using composition information derived from two dimensional gas chromatography in conjunction with the PETROTOX model.
In a read-across key semi-static 21 -day long-term Daphnia magna toxicity test (OECD 211; KS = 2), 10 animals/loading were exposed to the Water Accommodated Fraction (WAF) of other lubricant base oil LVIN 38 (CAS #64742-53-6) at nominal concentrations of 1, 10, 100 and 1000 mg/L. The NOEL was 10 mg/L based on reproduction. The loss of all daphnids in the 100 mg/L WAF was attributed to a non-treatment related effect, the cause of which was unknown. Further testing would be required to clarify the consequences of exposure to a 100 mg/L WAF of the base oil (Shell, 1995).
Results of computer modelling to estimate aquatic toxicity show no chronic toxicity of foots oil to freshwater aquatic invertebrates at or below its maximum attainable water solubility (Redman et al., 2010b). These results support the applied read across.
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