Acetic acid, C11-14-isoalkyl esters, C13-rich

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2016-08-01 to 2016-08-11

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Version / remarks:

23 March 2006

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

Date of inspection: 05/07/2016; Date of issue: 28/10/2016

Type of method:

gas saturation method

Key result

Test no.:

#1

Temp.:

25 °C

Vapour pressure:

0.51 Pa

Typical Chromatography

See attached.

The mean peak areas relating to the standard and sample solutions are shown in the following table:

Table 1 (25°C test)

Solution	Mean Peak Area
Standard at 151 mg/L	1.5780 x 10^7
Standard at 163 mg/L	1.8674 x 10^7
Matrix blank	None Detected
Saturator A Trap 1	1.0045 x 10^7
Saturator A Trap 2	None Detected
Saturator B Trap 1	1.3572 x 10^7
Saturator B Trap 2	None Detected
Saturator C Trap 1	1.6730 x 10^7
Saturator C Trap 2	None Detected

 

The mass of transferred test item and corresponding vapor pressures are shown in the following table:

Table 2 Results of the 25°C main vapour pressure determination

Saturator Column.	Temp. [°C]	Volume* V [mL]	Mass of Test Item in Trap 1 [μg]	Mass of Test Item in Trap 2 [μg] #	Total Mass of Test Item [μg]	Vapour Pressure [Pa]	Average Vapour Pressure [Pa] (Std Dev)
A	25	93489	4.58 x 10^3	0	4.58 x 10^3	0.508	0.510 (4.01 x 10^-3)
B		124652	6.18 x 10^3	0	6.18 x 10^3	0.514
C		155815	7.62 x 10^3	0	7.62 x 10^3	0.507

* Corrected volume at test temperature as calculated under “Volume correction”

# 0 μg refers to none detected within Trap 2

The tabulated results represent rounded-off values obtained by calculations based on the exact raw data.

Validation

The linearity of the detector response with respect to concentration was assessed over the concentration range of 1.01 to 253 mg/L (n = 6). The results were satisfactory with a correlation coefficient (r²) of 1.000 being obtained.

The concentrations in the sample solutions from Trap 1 ranged between 91.5 and 152 mg/L, therefore were within the calibration range. For Trap 2 no test item was detected.

Table 3 Trapping Efficiency

Saturator Column.	Temp. [°C]	Mass of Test Item in Trap 1 [μg]	Mass of Test Item in Trap 2 [μg]	Total Mass of Test Item [μg]	Percentage of Test Item in Trap 1	Percentage of Test Item in Trap 2	Total percentage of trapped Test Item
A		4.58 x 10^3	0	4.58 x 10^3	100	0	100
B		6.18 x 10^3	0	6.18 x 10^3	100	0	100
C		7.62 x 10^3	0	7.62 x 10^3	100	0	100

 

Discussion

To ensure saturation control, three different flow rates were used. From the data in Table 2 it can be clearly seen that higher flow rates did not lead to a lower vapour pressure, which indicates that the nitrogen was saturated with test item under the conditions of the test.

Conclusion

The vapour pressure of the test item has been determined to be 0.510 Pa at 25°C.

 

Conclusions:

A vapour pressure value of 0.510 ± 0.004 Pa at 25°C was determined for the substance using a relevant test method and in compliance with GLP. The result is considered to be reliable.

Description of key information

Vapour pressure: 0.510 ± 0.004 Pa at 25°C (OECD 104)

Key value for chemical safety assessment

Vapour pressure:

0.51 Pa

at the temperature of:

25 °C

Additional information

A measured vapour pressure value of 0.510 ± 0.004 Pa at 25°C was determined for the test substance using a gas saturation method in accordance with OECD Test Guideline 104 and in compliance with GLP. The result is considered to be reliable and is selected as key study.

In a supporting study, vapour pressure value of 0.534 Pa at 20°C was obtained for the substance using a relevant test method.