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EC number: 276-882-8 | CAS number: 72828-69-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 11 October 1994 to 16 June 1995
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- yes
- Remarks:
- Limit test: 3 concentrations tested
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Swiss GLP
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch number of test material: 1
- Expiration date of the lot/batch: Oct 1998
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: room temperature
- Solubility of the test substance in the solvent/dispersant/vehicle/test medium: miscible - Analytical monitoring:
- yes
- Details on sampling:
- All test medium samples for the analytical determinations were taken from the approximate center of the test vessels (without mixing the medium) and kept at -18 °C to -25 °C until analysis.
The concentrations of the test substance at the beginning and at the end of the test were analysed by the PE Analytical Services K, Textile Dyes Division. - Vehicle:
- yes
- Details on test solutions:
- Stock solution
0.09 g test substance were mixed with 200 ml test medium in a beaker, was homogenized for 25 minutes by ultrasonic treatment and filled up to 500 ml with test medium.
Since the test substance was insoluble in the test medium, most of the test substance settled down and built a sediment at the bottom of the flask.
Test concentrations
The nominal test concentrations were chosen as 58 /100 and 180 mg test article/I. For the preparation of the test concentrations only the supernatant of the stock solution was taken.
All test concentrations contained the vehicle Tween 80 (Polyoxyethylensorbitanmonooleat) in a concentration of 5 ppm. - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- The organism used in this test system is the species Daphnia magna. The Daphnia were bred in the laboratories of the Product Ecology TF, Textile Dyes Division under standardised conditions.
Breeding:
- Cultures of Daphnia magna are held in glass vessels containing approx. 3.0 litre of reconstituted water at 18 - 22 °C. The water was renewed partially three times per week. The daphnids were fed with a suspension of green algae (Scenedesmus subspicatus) supplemented by a TETRAMIN-extract in such quantities that the food was consumed within 24 h.
Pretreatment:
- 24 hours before the start of the exposure reproductive daphnids were separated from the young daphnids by sieving all individuals through a 1000 µrn sieve. For each test concentration, 20 daphnids divided in two groups of 10 animals were used. - Test type:
- not specified
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Remarks on exposure duration:
- None
- Post exposure observation period:
- None
- Hardness:
- 232 mg/l CaCO3
- Test temperature:
- 48 h at 21 ± 1 °C, 12 h light/12 hours dark.
- pH:
- None
- Conductivity:
- None
- Nominal and measured concentrations:
- The nominal test concentrations were chosen as 58 /100 and 180 mg test article/I. For the preparation of the test concentrations only the supernatant of the stock solution was taken.
All test concentrations contained the vehicle Tween 80 (Polyoxyethylensorbitanmonooleat) in a concentration of 5 ppm. - Details on test conditions:
- None
- Reference substance (positive control):
- yes
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 51.1 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Key result
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 25.4 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Details on results:
- The test concentrations were prepared from a 0.18 g/l stock solution. Although, the test substance is miscible in pure (deionised) water, most of the test substance in the stock solution settled down and build a sediment at the bottom of the flask. This effect was possibly caused by a reaction of the test substance with the water hardness compounds in the test water. For the preparation of the test concentrations only the supernatant of the stock solution was taken ( limit of the solubility). The nominal concentrations tested were 58 / 100 and 180 mg test article/I, a blank and a vehicle control without any additions. In the two highest test concentrations again a small sediment at the bottom of the test vessel was observed after 48 hours. Because of the low solubility of the test article in the test media the actual test conentrations in the analysed test media were in the range of 18.5 - 36.3 % of the nominal values. Therefore, the reported results are related to the actual mean values of the analysed test concentrations of the test article measured after beginning and at the end of the test. No immobilization and abnormal behaviour of the Daphnia was observed in the controls. The NOEC and EC0 value after 48 h were determined to be 25.4 mg/l, the EC50 and the EC100 value could not be calculated, but are clearly higher than 51.1 mg/l.
- Validity criteria fulfilled:
- yes
- Conclusions:
- The NOEC and EC0 of FAT 21015/B after 48 h were determined to be 25.4 mg/l.
- Executive summary:
The acute toxicity of FAT 21015/B to Daphnia magna was determined in a 48-h static test according to the OECD Guideline for Testing of Chemicals, No. 202, adopted 4 April 1984 and EEC-Directive , L 251, C. 2. The study was performed under Good Laboratory Practice (GLP) conditions. The test concentrations were prepared from a 0.18 g/l stock solution. Although the test substance is miscible in pure (deionised) water, most of the test substance in the stock solution settled down and build a sediment at the bottom of the flask. This effect was possibly caused by a reaction of the test substance with the water hardness compounds in the test water. For the preparation of the test concentrations only the supernatant of the stock solution was taken ( limit of the solubility). The nominal concentrations tested were 58/100 and 180 mg test article/l, a vehicle and a blank control without any addtions. In the two highest test concentrations again a small sediment at the bottom of the test vessel was observed after 48 h. Because of the low solubility of the test article in the test media, the actual test concentrations in the analysed test media were in the range of 18.5 - 36.3 % of the nominal values. Therefore, the reported results are related to the actual mean values of the analysed conentrations of the test article measured at the beginning and at the end of the test.
No immobilization and abnormal behaviour of the Daphnia was observed in the controls. The NOEC and EC0 value after 48 h were determined to be 25.4 mg/l, the EC50 and the EC100 value could not be calculated, but are clearly higher than 51.1 mg/l.
Reference
Description of key information
The acute toxicity of FAT 21015/B to Daphnia magna was determined in a 48-h static test according to the OECD Guideline 202 1984 and EU method C. 2. The study was performed under Good Laboratory Practice (GLP) conditions. The test concentrations were prepared from a 0.18 g/l stock solution. Although the test substance is miscible in pure (deionised) water, most of the test substance in the stock solution settled down and build a sediment at the bottom of the flask. This effect was possibly caused by a reaction of the test substance with the water hardness compounds in the test water. For the preparation of the test concentrations only the supernatant of the stock solution was taken (limit of the solubility). The nominal concentrations tested were 58/100 and 180 mg test article/l, a vehicle and a blank control without any addtions. In the two highest test concentrations again a small sediment at the bottom of the test vessel was observed after 48 h. Because of the low solubility of the test article in the test media, the actual test concentrations in the analysed test media were in the range of 18.5 - 36.3 % of the nominal values. Therefore, the reported results are related to the actual mean values of the analysed conentrations of the test article measured at the beginning and at the end of the test. No immobilization and abnormal behaviour of the Daphnia was observed in the controls. The NOEC and EC0 value after 48 h were determined to be 25.4 mg/l, the EC50 and the EC100 value could not be calculated, but are clearly higher than 51.1 mg/l.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 51.1 mg/L
Additional information
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