Registration Dossier
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EC number: 271-689-5 | CAS number: 68604-38-6
Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
Description of key information
The chemical safety assessment according to Annex I of Regulation (EC) No. 1907/2006 does not indicate the need to investigate further the toxicity to terrestrial plants.
Key value for chemical safety assessment
Additional information
Experimental data on the toxicity of Fatty acids, C16-18 and C18-unsatd., hexaesters with dipentaerythritol (CAS 68604-38-6) to terrestrial plants are not available. In accordance with Regulation (EC) No. 1907/2006, Annex IX, column 2, 9.4 studies on terrestrial organisms do not need to be conducted when there is no risk indicated by the chemical safety assessment.
Based on the available experimental toxicity data the substance is
expected to be not toxic to soil organisms. The substance is expected to
be largely physically removed in sewage treatment plants and thus a
transfer to the terrestrial environment is not likely. If transferred to
the soil an adsorption to soil particles is probable as indicated by the
high log Koc (C16 FA component: 2.27, C18 unsat. FA component: 46.87,
C18 FA component: 48.16; KOWWIN v1.68; Blum, 2011). Furthermore the
substance has a low water solubility (< 0.15 mg/L, Frischmann, 2012)
indicating that its concentrations in soil pore water are negligible.
Thus, the substance is presumably not available for plants in the soil.
An uptake of the substance by plant roots is also hindered by the high
molecular weight of the substance (1684 – 1853 g/mol) preventing the
substance from crossing biological membranes. However, acute or chronic
toxicity of the substance to terrestrial organisms is generally not
expected. The lack of chronic toxicity of the substance was demonstrated
by a study chronic toxicity on Eisenia fetida (OECD 222). Neither
mortality nor an effect on earthworm reproduction was observed (NOEC ≥
1000 mg/kg soil dw).
In conclusion, the substance is unlikely to pose a risk for terrestrial
plants based on a) the lack of exposure and b) the low toxicity as
expected for this substance for the terrestrial compartment based on the
available experimental data, metabolism considerations and the lack of
adverse effects in aquatic ecotoxicity tests.
In accordance with Regulation (EC) No. 1907/2006, Annex X, Column 2, 9.4
further studies on the effects on terrestrial organisms do not have to
be conducted since the chemical safety assessment indicates that
toxicity to terrestrial plants is not expected to be of concern.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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