Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Acute dermal irritation on an analogue of the substance has been assessed in the rabbit using OECD/EU test methods. The irritation observed was not of sufficient severity or persistence for the substance to require classification as a skin irritant. This is supported by in-vitro studies on the substance itself and a number of analogues.

Acute eye irritation of an analogue of the substance has been assessed in the rabbit using OECD/EU test methods. The severity and persistence of ocular response was sufficient for the substance to require classification as an eye irritant.

Justification for selection of skin irritation / corrosion endpoint:

Several studies available for evaluation

Justification for selection of eye irritation endpoint:

Single study available for evaluation

Effects on eye irritation: highly irritating

Justification for classification or non-classification

Skin:

Based on the results of the available data the substance does not require to be classified and labelled according to Regulation 1272/2008/EC (CLP) or Directive 67/548/EEC (DSD).

Eyes:

The information available is regarded as sufficient to be able to draw conclusions regarding the need for classification. Classification as serious eye damage Category 1 - H318 according to CLP (1272/2008/EC) and risk of serious damage to eyes - R41 according to 67/548/EEC is indicated.