Registration Dossier
Registration Dossier
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EC number: 258-416-5 | CAS number: 53179-11-6
Auto flammability
Administrative data
- Endpoint:
- relative self-ignition temperature (solids)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Report date:
- 2014
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.16 (Relative Self-Ignition Temperature for Solids)
- GLP compliance:
- no
Test material
- Reference substance name:
- Loperamide
- EC Number:
- 258-416-5
- EC Name:
- Loperamide
- Cas Number:
- 53179-11-6
- Molecular formula:
- C29H33ClN2O2
- IUPAC Name:
- 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- Test item identification : 4-(4-clorofenil)-4-idrossi-N,N-dimetil-a,a-difenil-1--piperidinbutanamide
Purity : 99.7 % w/w
Expiry date : June 01, 2015
Constituent 1
Results and discussion
Relative self-ignition temperature (solids)
- Relative self-ignition temperature:
- > 400 °C
- Remarks on result:
- other:
Any other information on results incl. tables
The test was performed over a period of 14 hours, from 20°C to 400°C.
The test item behaviour didn’t show a variation in comparison with the oven recorded
temperature. No exothermic effect was observed.
Applicant's summary and conclusion
- Conclusions:
- From the experimental data obtained according to A.16 method in Council Regulation (EC)
No 440/2008 of 30 May 2008, it can be concluded that the 4-(4-chlorophenyl)-4-hydroxy-N,Ndimethyl-
a,a-diphenyl sample does not present a relative self-ignition temperature below
400°C.
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