Registration Dossier
Registration Dossier
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EC number: 250-284-7 | CAS number: 30674-80-7
Dissociation constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- dissociation constant
- Data waiving:
- other justification
- Justification for data waiving:
- the study does not need to be conducted because the substance is hydrolytically unstable (half-life less than 12 hours)
- Endpoint:
- dissociation constant
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Accepted calculation method
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
- Principles of method if other than guideline:
- Calculation with use of SPARC pKa online calculator v 4.6, chemical reactivity models for estimation of ionisation pKa in water.
- GLP compliance:
- no
- Dissociating properties:
- no
Referenceopen allclose all
For detailed description on the model and its applicability, see "Any other information on materials and methods incl. tables".
Description of key information
not applicable
Key value for chemical safety assessment
Additional information
The substance 2-isocyanatoethyl methacrylate (CAS 30674-80-7) is hydrolytically unstable (half-life less than 12 hours) and has no dissociable groups. QSAR calculations performed with SPARC v4.6 show that the substance does not dissociate in pH range -0.2 to 14.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
