Registration Dossier
Registration Dossier
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EC number: 249-978-2 | CAS number: 29964-84-9
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
A bioconcentration study study on the structural analogue 2-ethylhexyl methacrylate according
to OECD guideline 305 demonstrates that a rapid metabolism occurs, preventing any significant accumulation (BCF = 37).
Key value for chemical safety assessment
Additional information
The octanol/water partition coefficient of the substance, log Kow > 4, predicts a potential for bioaccumulation. Simple models linking BCF to logKow would give BCF in the range of about > 1000 depending on the model and the logKow used . On the contrary, an experimental study (Fraunhofer, 2006) has been carried out on the structural analogue 2-ethyl hexyl methacrylate (log Kow > 4) to assess the fish bioconcentration of the substance, according to OECD guideline 305. This study demonstrates that a rapid metabolisation occurs, preventing any significant accumulation (BCF = 37).
For read across purposes according to ECHA's RAAF (2017), this study is applicable with a high level of confidence.
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