Registration Dossier
Registration Dossier
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EC number: 249-942-6 | CAS number: 29901-62-0
Endpoint summary
Administrative data
Description of key information
No experimental data is available regarding irritating properties. Sulfanilic acid is classified as irritating to skin and eyes (R36/38). For the test substance, this classification is considered adequate.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
No experimental data about skin or eye irritation of the test material are available. But there are several data from study reports, public journals and other literature sources which describe and characterize sulfanilic acid as well as the sodium salt.It is acceptable to derive irritation / corrosive properties from experimental data of sulfanilic acid and the sodium analogue. The potassium salt as well as the sodium salt dissociates in aqueous solution in free sulfanilic acid and the respective ions.
Sulfanilic acid is described to be irritating on eyes and skin. The substance is classified as "irrating" with R36 / 38 and Xi. For the test substance, this classification would be also acceptable. There are no data available about respiratory irritation.
Effects on skin irritation/corrosion: irritating
Effects on eye irritation: irritating
Justification for classification or non-classification
Dangerous Substance Directive (67/548/EEC)
The available studies for read across substances are considered reliable and suitable for classification purposes under 67/548/EEC. It was shown that the read across substances cause irritation to skin and eyes. A
s a result the substance is considered to be classified for skin and eye irritation under Directive 67/548/EEC, as amended for the 28th time in Directive 2001/59/EC.
Classification, Labelling, and Packaging Regulation (EC) No. 1272/2008
The available experimental test data for read across substances are reliable and suitable for classification purposes under Regulation 1272/2008. It was shown that the read across substances cause irritation to skin and eyes.
As a result the substance is considered to be classified for skin and eye irritation under Regulation (EC) No. 1272/2008.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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