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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods
Justification for type of information:
Experimental result using standard methods of analysis
Qualifier:
according to guideline
Guideline:
other: HPLC Method
Principles of method if other than guideline:
The water solubility determination of test chemical was done as per the HPLC method
GLP compliance:
no
Type of method:
other: HPLC method
Key result
Water solubility:
0.015 mg/L
Conc. based on:
test mat.
Temp.:
25 °C
Remarks on result:
other: Insoluble in water

TABLE-1: TEST DESCRIPTION AND RESULT

 

Sr. no

Sample Concentration

By % Area (mg/l)

Temperature

Dilution Factor

1

0.003

250C

5

2

0.003

250C

5

Mean

0.003

250C

5

CALCULATIONS:              

Water solubility was calculated using the formula:   

Water Solubility(mg/l)=   Mean Sample concentration (mg/l) ×  Dilution factor

Conclusions:
The water solubility determination of test chemical was done by HPLC method. The water solubility was determined to be 0.015 mg/l at 25°C.
Executive summary:

The water solubility determination of test chemical was done by HPLC method. The water solubility was determined to be 0.015 mg/l at 25°C. On the basis of this value, test chemical is considered to be insoluble in water.

Description of key information

Based on the available data from study report, the water solubility determination of test chemical was done by HPLC method. The water solubility was determined to be 0.015 mg/l at 25°C. On the basis of this value, test chemical is considered to be insoluble in water.

Key value for chemical safety assessment

Water solubility:
0.015 mg/L
at the temperature of:
25 °C

Additional information

Based on the available data from study report, the water solubility determination of test chemical was done by HPLC method. The water solubility was determined to be 0.015 mg/l at 25°C. On the basis of this value, test chemical is considered to be insoluble in water.

Another study from secondary source also indicates that the test chemical is insoluble in water.